| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yuan Yang, Meikui Zhang, Xiaoni Kang, Chen Jiang, Huan Zhang, Pei Wang, Jingjing L. Impaired adult hippocampal neurogenesis and cognitive ability in a mouse model of intrastriatal hemorrhage. Neuroscience letters. vol 599. 2015-10-16. PMID:26021875. |
after 1 u thrombin injection, cell apoptosis was found at the dentate gyrus of hippocampus at 3-24 h, but not 5 d post-injury. |
2015-10-16 |
2023-08-13 |
mouse |
| R-H Yang, J Lin, X-H Hou, R Cao, F Yu, H-Q Liu, A-L Ji, X-N Xu, L Zhang, F Wan. Effect of docosahexaenoic acid on hippocampal neurons in high-glucose condition: involvement of PI3K/AKT/nuclear factor-κB-mediated inflammatory pathways. Neuroscience. vol 274. 2015-10-15. PMID:24881575. |
the present study investigated the effects of dha on the lipid peroxidation, the level of inflammatory cytokines and neuron apoptosis in the hippocampal neurons in high-glucose condition. |
2015-10-15 |
2023-08-13 |
Not clear |
| R-H Yang, J Lin, X-H Hou, R Cao, F Yu, H-Q Liu, A-L Ji, X-N Xu, L Zhang, F Wan. Effect of docosahexaenoic acid on hippocampal neurons in high-glucose condition: involvement of PI3K/AKT/nuclear factor-κB-mediated inflammatory pathways. Neuroscience. vol 274. 2015-10-15. PMID:24881575. |
high-glucose administration increased the level of tumor necrosis factor α (tnf-α) and il-6, induced oxidative stress and apoptosis of hippocampal neurons in vitro. |
2015-10-15 |
2023-08-13 |
Not clear |
| Sooyong Kim, Il-Hwan Kang, Jung-Bum Nam, Yoonchul Cho, Doo-Young Chung, Seung-Hwan Kim, Jeong-Soo Kim, Yong-Deok Cho, Eun-Ki Hong, Nak-Won Sohn, Jung-Won Shi. Ameliorating the effect of astragaloside IV on learning and memory deficit after chronic cerebral hypoperfusion in rats. Molecules (Basel, Switzerland). vol 20. issue 2. 2015-10-13. PMID:25625683. |
as-iv significantly attenuated neuronal apoptosis as well as the levels of superoxide dismutase and lipid peroxidation markers, including malondialdehyde and 4-hydroxy-2-nonenal, in the hippocampus. |
2015-10-13 |
2023-08-13 |
rat |
| Sooyong Kim, Il-Hwan Kang, Jung-Bum Nam, Yoonchul Cho, Doo-Young Chung, Seung-Hwan Kim, Jeong-Soo Kim, Yong-Deok Cho, Eun-Ki Hong, Nak-Won Sohn, Jung-Won Shi. Ameliorating the effect of astragaloside IV on learning and memory deficit after chronic cerebral hypoperfusion in rats. Molecules (Basel, Switzerland). vol 20. issue 2. 2015-10-13. PMID:25625683. |
the results indicate that as-iv has therapeutic potential for the prevention of dementia caused by cerebral hypoperfusion and suggest that the ameliorating effect of as-iv on learning and memory deficits might be the result of suppressing neuronal apoptosis and oxidative damage in the hippocampus. |
2015-10-13 |
2023-08-13 |
rat |
| Hong Xu, Thomas W Rösler, Thomas Carlsson, Anderson de Andrade, Ondrej Fiala, Matthias Hollerhage, Wolfgang H Oertel, Michel Goedert, Achim Aigner, Gunter U Höglinge. Tau silencing by siRNA in the P301S mouse model of tauopathy. Current gene therapy. vol 14. issue 5. 2015-10-13. PMID:25687501. |
neun, gfap, iba-1, mhc ii immunoreactivities and the terminal deoxynucleotidyl transferase dutp nick end labeling (tunel) assay showed neither signs of neurotoxicity or neuroinflammation nor apoptosis when mapt sirna is present in the hippocampus. |
2015-10-13 |
2023-08-13 |
mouse |
| Yuling Zhong, Yubing Liang, Jing Chen, Li Li, Yi Qin, Enjian Guan, Dan He, Yi Wei, Yubo Xie, Qiang Xia. Propofol inhibits proliferation and induces neuroapoptosis of hippocampal neurons in vitro via downregulation of NF-κB p65 and Bcl-2 and upregulation of caspase-3. Cell biochemistry and function. vol 32. issue 8. 2015-10-05. PMID:25431245. |
a significant decrease in neuronal proliferation and a remarkable increase in neuroapoptosis were observed in div 7 hippocampal neurons as measured by 3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromide assay and apoptosis assay respectively. |
2015-10-05 |
2023-08-13 |
Not clear |
| H Xie, G-M She, C Wang, L-Y Zhang, C-F Li. The gender difference in effect of sevoflurane exposure on cognitive function and hippocampus neuronal apoptosis in rats. European review for medical and pharmacological sciences. vol 19. issue 4. 2015-10-01. PMID:25753883. |
the gender difference in effect of sevoflurane exposure on cognitive function and hippocampus neuronal apoptosis in rats. |
2015-10-01 |
2023-08-13 |
rat |
| b' Mustafa Naz\\xc4\\xb1ro\\xc4\\x9flu, Fatma Feyza \\xc3\\x96zkan, Seher Rabia Hapil, Vahid Ghazizadeh, Bilal \\xc3\\x87i\\xc4\\x9. Epilepsy but not mobile phone frequency (900 MHz) induces apoptosis and calcium entry in hippocampus of epileptic rat: involvement of TRPV1 channels. The Journal of membrane biology. vol 248. issue 1. 2015-09-28. PMID:25381485.' |
epilepsy but not mobile phone frequency (900 mhz) induces apoptosis and calcium entry in hippocampus of epileptic rat: involvement of trpv1 channels. |
2015-09-28 |
2023-08-13 |
rat |
| b' Mustafa Naz\\xc4\\xb1ro\\xc4\\x9flu, Fatma Feyza \\xc3\\x96zkan, Seher Rabia Hapil, Vahid Ghazizadeh, Bilal \\xc3\\x87i\\xc4\\x9. Epilepsy but not mobile phone frequency (900 MHz) induces apoptosis and calcium entry in hippocampus of epileptic rat: involvement of TRPV1 channels. The Journal of membrane biology. vol 248. issue 1. 2015-09-28. PMID:25381485.' |
we investigated the effects of mobile phone (900 mhz) emr exposure on ca(2+) influx, apoptosis, oxidative stress, and trpv1 channel activations in the hippocampus of pentylenetetrazol (ptz)-induced epileptic rats. |
2015-09-28 |
2023-08-13 |
rat |
| b' Mustafa Naz\\xc4\\xb1ro\\xc4\\x9flu, Fatma Feyza \\xc3\\x96zkan, Seher Rabia Hapil, Vahid Ghazizadeh, Bilal \\xc3\\x87i\\xc4\\x9. Epilepsy but not mobile phone frequency (900 MHz) induces apoptosis and calcium entry in hippocampus of epileptic rat: involvement of TRPV1 channels. The Journal of membrane biology. vol 248. issue 1. 2015-09-28. PMID:25381485.' |
in conclusion, apoptosis, mitochondrial, ros, and ca(2+) influx via trpv1 channel were increased in the hippocampal neurons by epilepsy induction although the mobile phone did not change the values. |
2015-09-28 |
2023-08-13 |
rat |
| N Çabuş, E O Oğuz, A Ç Tufan, E Adıgüze. A histological study of toxic effects of aluminium sulfate on rat hippocampus. Biotechnic & histochemistry : official publication of the Biological Stain Commission. vol 90. issue 2. 2015-09-25. PMID:25314162. |
we investigated changes in numbers of hippocampal neurons in rats exposed to aluminium using an optical fractionator and we investigated aluminium-induced apoptosis using the transferase mediated dutp nick end labeling (tunel) assay. |
2015-09-25 |
2023-08-13 |
human |
| N Çabuş, E O Oğuz, A Ç Tufan, E Adıgüze. A histological study of toxic effects of aluminium sulfate on rat hippocampus. Biotechnic & histochemistry : official publication of the Biological Stain Commission. vol 90. issue 2. 2015-09-25. PMID:25314162. |
we quantified the toxic effects of aluminium on the rat hippocampus and determined that apoptosis was the mechanism of aluminium-induced neuron death in the hippocampus. |
2015-09-25 |
2023-08-13 |
human |
| Huan Zhang, Rui Xu, Fei Xie, Wei Xu, Meng-Fei Zeng, Xin Wang, Ji Zh. Protective effects of perfluorooctyl-bromide nanoparticles on early brain injuries following subarachnoid hemorrhage in rats. American journal of translational research. vol 7. issue 8. 2015-09-23. PMID:26396671. |
electron microscopy revealed reduction of neuronal apoptosis, alleviation of glial cell swelling, and mitigation of perivascular edema in the hippocampal region. |
2015-09-23 |
2023-08-13 |
rat |
| Zhi-Guo Zhang, Xin Sun, Qing-Zhu Zhang, Hua Yan. Neuroprotective effects of ultra-low-molecular-weight heparin on cerebral ischemia/reperfusion injury in rats: involvement of apoptosis, inflammatory reaction and energy metabolism. International journal of molecular sciences. vol 14. issue 1. 2015-09-16. PMID:23344063. |
at the same time, ulmwh inhibited the neural apoptosis and decreased the expressions of icam-1 and caspase-3 mrna in hippocampus. |
2015-09-16 |
2023-08-12 |
rat |
| N Hettiarachchi, M Dallas, M Al-Owais, H Griffiths, N Hooper, J Scragg, J Boyle, C Peer. Heme oxygenase-1 protects against Alzheimer's amyloid-β(1-42)-induced toxicity via carbon monoxide production. Cell death & disease. vol 5. 2015-09-11. PMID:25501830. |
since apoptosis contributes to the neuronal loss associated with amyloid β peptide (aβ) toxicity in ad, we investigated the protective effects of ho-1 and co against aβ(1-42) toxicity in sh-sy5y cells, employing cells stably transfected with empty vector or expressing the cellular prion protein, prp(c), and rat primary hippocampal neurons. |
2015-09-11 |
2023-08-13 |
rat |
| Shu-e Cao, Jianmin Tian, Shengyang Chen, Xiaoran Zhang, Yongqiang Zhan. Role of miR-34c in ketamine-induced neurotoxicity in neonatal mice hippocampus. Cell biology international. vol 39. issue 2. 2015-09-10. PMID:25052764. |
functional assay of silencing mir-34c demonstrated that downregulation of mir-34c activated pkc-erk pathway, upregulated anti-apoptotic protein bcl2, and ameliorated ketamine-induced apoptosis in the hippocampus. |
2015-09-10 |
2023-08-13 |
mouse |
| Farzaneh Bagheri-Abassi, Hassan Alavi, Abbas Mohammadipour, Fatemeh Motejaded, Alireza Ebrahimzadeh-Bideska. The effect of silver nanoparticles on apoptosis and dark neuron production in rat hippocampus. Iranian journal of basic medical sciences. vol 18. issue 7. 2015-09-09. PMID:26351553. |
the effect of silver nanoparticles on apoptosis and dark neuron production in rat hippocampus. |
2015-09-09 |
2023-08-13 |
rat |
| Zhu-Xin Sui, Hao Liu, Hai-Tao Wang, Zhan-Ling Yang, Ji-Gang Liu, Ai-Jun Xu, He-Xiang L. [Alteration of apoptosis and Akt/mTOR signal pathway in hippocampal neurons of rat with post-traumatic stress]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition. vol 45. issue 2. 2015-09-08. PMID:24749344. |
[alteration of apoptosis and akt/mtor signal pathway in hippocampal neurons of rat with post-traumatic stress]. |
2015-09-08 |
2023-08-13 |
rat |
| Zhu-Xin Sui, Hao Liu, Hai-Tao Wang, Zhan-Ling Yang, Ji-Gang Liu, Ai-Jun Xu, He-Xiang L. [Alteration of apoptosis and Akt/mTOR signal pathway in hippocampal neurons of rat with post-traumatic stress]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition. vol 45. issue 2. 2015-09-08. PMID:24749344. |
to observe the changes of apoptosis and protein kinase b/the mammalian target of rapamycin (akt/mtor) signal pathway in hippocampal neurons of rat with post-straumatic stress disorder (ptsd), and to investigate the mechanism of ptsd. |
2015-09-08 |
2023-08-13 |
rat |