Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Minmin Zhu, Jiawei Chen, Meilin Wen, Zhirong Sun, Xia Sun, Jing Wang, Changhong Mia. Propofol protects against angiotensin II-induced mouse hippocampal HT22 cells apoptosis via inhibition of p66Shc mitochondrial translocation. Neuromolecular medicine. vol 16. issue 4. 2015-07-20. PMID:25151272. |
in this study, we investigated the mechanism how propofol protected mouse hippocampal ht22 cells against angiotensin ii-induced oxidative stress and apoptosis. |
2015-07-20 |
2023-08-13 |
mouse |
Minmin Zhu, Jiawei Chen, Meilin Wen, Zhirong Sun, Xia Sun, Jing Wang, Changhong Mia. Propofol protects against angiotensin II-induced mouse hippocampal HT22 cells apoptosis via inhibition of p66Shc mitochondrial translocation. Neuromolecular medicine. vol 16. issue 4. 2015-07-20. PMID:25151272. |
by these mechanisms, it protects mouse hippocampal ht22 cells against angiotensin ii-induced apoptosis. |
2015-07-20 |
2023-08-13 |
mouse |
Chunhong Liang, Shimei Tan, Quanfang Huang, Jun Lin, Zhongpeng Lu, Xing Li. Pratensein ameliorates β-amyloid-induced cognitive impairment in rats via reducing oxidative damage and restoring synapse and BDNF levels. Neuroscience letters. vol 592. 2015-07-15. PMID:25748315. |
pratensein treatment significantly attenuated neuronal degeneration and apoptosis in hippocampus. |
2015-07-15 |
2023-08-13 |
rat |
P K Multani, R Hodge, M A Estévez, T Abel, H Kung, M Alter, B Brookshire, I Lucki, A H Nall, K Talbot, G A Doyle, F W Lohof. VMAT1 deletion causes neuronal loss in the hippocampus and neurocognitive deficits in spatial discrimination. Neuroscience. vol 232. 2015-07-14. PMID:23201251. |
deletion of vmat1 leads to increased hippocampal apoptosis and reduced neurogenesis as assessed by caspase-3-labeling and 5-bromo-deoxy-uridine-labeling. |
2015-07-14 |
2023-08-12 |
mouse |
Haiquan Wang, Zhengbu Liao, Xiaochuan Sun, Quanhong Shi, Gang Huo, Yanfeng Xie, Xiaolan Tang, Xinggang Zhi, Zhaohua Tan. Intravenous administration of Honokiol provides neuroprotection and improves functional recovery after traumatic brain injury through cell cycle inhibition. Neuropharmacology. vol 86. 2015-07-14. PMID:24973706. |
the neuronal degeneration and apoptosis in the cortex and hippocampus were further significantly attenuated by honokiol treatment. |
2015-07-14 |
2023-08-13 |
rat |
Eun-Sang Ji, You-Mi Kim, Mal-Soon Shin, Chang-Ju Kim, Kwang-Sik Lee, Kijeong Kim, Jonglin Ha, Yong-Rak Chun. Treadmill exercise enhances spatial learning ability through suppressing hippocampal apoptosis in Huntington's disease rats. Journal of exercise rehabilitation. vol 11. issue 3. 2015-07-14. PMID:26171378. |
treadmill exercise enhances spatial learning ability through suppressing hippocampal apoptosis in huntington's disease rats. |
2015-07-14 |
2023-08-13 |
rat |
Eun-Sang Ji, You-Mi Kim, Mal-Soon Shin, Chang-Ju Kim, Kwang-Sik Lee, Kijeong Kim, Jonglin Ha, Yong-Rak Chun. Treadmill exercise enhances spatial learning ability through suppressing hippocampal apoptosis in Huntington's disease rats. Journal of exercise rehabilitation. vol 11. issue 3. 2015-07-14. PMID:26171378. |
in the present study, the effect of treadmill exercise on spatial-learning ability and motor coordination focusing on the apoptosis in the hippocampus was investigated using quinolinic acid-induced huntington's disease rats. |
2015-07-14 |
2023-08-13 |
rat |
Eun-Sang Ji, You-Mi Kim, Mal-Soon Shin, Chang-Ju Kim, Kwang-Sik Lee, Kijeong Kim, Jonglin Ha, Yong-Rak Chun. Treadmill exercise enhances spatial learning ability through suppressing hippocampal apoptosis in Huntington's disease rats. Journal of exercise rehabilitation. vol 11. issue 3. 2015-07-14. PMID:26171378. |
the present results showed that treadmill exercise might ameliorate quinolinic acid-induced loss of spatial learning ability and motor coordination by suppressing apoptosis in the hippocampus. |
2015-07-14 |
2023-08-13 |
rat |
Shao-hua Wang, Yan Huang, Yang Yuan, Wen-qing Xia, Pin Wang, Rong Huan. LDL receptor knock-out mice show impaired spatial cognition with hippocampal vulnerability to apoptosis and deficits in synapses. Lipids in health and disease. vol 13. 2015-07-13. PMID:25413784. |
ldl receptor knock-out mice show impaired spatial cognition with hippocampal vulnerability to apoptosis and deficits in synapses. |
2015-07-13 |
2023-08-13 |
mouse |
Weina Yang, Lili Shi, Lianji Chen, Bingyi Zhang, Kaige Ma, Yong Liu, Yihua Qia. Protective effects of perindopril on d-galactose and aluminum trichloride induced neurotoxicity via the apoptosis of mitochondria-mediated intrinsic pathway in the hippocampus of mice. Brain research bulletin. vol 109. 2015-07-10. PMID:25290208. |
protective effects of perindopril on d-galactose and aluminum trichloride induced neurotoxicity via the apoptosis of mitochondria-mediated intrinsic pathway in the hippocampus of mice. |
2015-07-10 |
2023-08-13 |
mouse |
Weina Yang, Lili Shi, Lianji Chen, Bingyi Zhang, Kaige Ma, Yong Liu, Yihua Qia. Protective effects of perindopril on d-galactose and aluminum trichloride induced neurotoxicity via the apoptosis of mitochondria-mediated intrinsic pathway in the hippocampus of mice. Brain research bulletin. vol 109. 2015-07-10. PMID:25290208. |
taken together, the above findings indicated that perindopril inhibited apoptosis in the hippocampus may be another mechanism by which perindopril improves learning and memory functions in d-gal and alcl₃ treated mice. |
2015-07-10 |
2023-08-13 |
mouse |
Qianfa Long, Cairui Fan, Wang Kai, Qiang Luo, Weichuan Xin, Ping Wang, Ansheng Wang, Zhanyao Wang, Rui Han, Zhou Fei, Bensheng Qiu, Weiping Li. Hypoxia inducible factor-1α expression is associated with hippocampal apoptosis during epileptogenesis. Brain research. vol 1590. 2015-07-09. PMID:25242614. |
hypoxia inducible factor-1α expression is associated with hippocampal apoptosis during epileptogenesis. |
2015-07-09 |
2023-08-13 |
rat |
Qianfa Long, Cairui Fan, Wang Kai, Qiang Luo, Weichuan Xin, Ping Wang, Ansheng Wang, Zhanyao Wang, Rui Han, Zhou Fei, Bensheng Qiu, Weiping Li. Hypoxia inducible factor-1α expression is associated with hippocampal apoptosis during epileptogenesis. Brain research. vol 1590. 2015-07-09. PMID:25242614. |
cell apoptosis can cause hippocampal neuronal loss after epileptic seizures. |
2015-07-09 |
2023-08-13 |
rat |
Qianfa Long, Cairui Fan, Wang Kai, Qiang Luo, Weichuan Xin, Ping Wang, Ansheng Wang, Zhanyao Wang, Rui Han, Zhou Fei, Bensheng Qiu, Weiping Li. Hypoxia inducible factor-1α expression is associated with hippocampal apoptosis during epileptogenesis. Brain research. vol 1590. 2015-07-09. PMID:25242614. |
here, we used a rat model of pilocarpine-induced status epilepticus (se) to investigate hif-1α expression and apoptosis in the hippocampus, and to explore their relationship during epileptogenesis. |
2015-07-09 |
2023-08-13 |
rat |
Qianfa Long, Cairui Fan, Wang Kai, Qiang Luo, Weichuan Xin, Ping Wang, Ansheng Wang, Zhanyao Wang, Rui Han, Zhou Fei, Bensheng Qiu, Weiping Li. Hypoxia inducible factor-1α expression is associated with hippocampal apoptosis during epileptogenesis. Brain research. vol 1590. 2015-07-09. PMID:25242614. |
then the hif-1α expression and hippocampal apoptosis were investigated by histological confirmation and western blotting at 24h, 3d, 7d and 14d, respectively. |
2015-07-09 |
2023-08-13 |
rat |
Qianfa Long, Cairui Fan, Wang Kai, Qiang Luo, Weichuan Xin, Ping Wang, Ansheng Wang, Zhanyao Wang, Rui Han, Zhou Fei, Bensheng Qiu, Weiping Li. Hypoxia inducible factor-1α expression is associated with hippocampal apoptosis during epileptogenesis. Brain research. vol 1590. 2015-07-09. PMID:25242614. |
the results showed that the administration of mk-801 significantly reduced (p<0.05) hif-1α expression and hippocampal apoptosis during epileptogenesis in comparison with the positive control. |
2015-07-09 |
2023-08-13 |
rat |
Qianfa Long, Cairui Fan, Wang Kai, Qiang Luo, Weichuan Xin, Ping Wang, Ansheng Wang, Zhanyao Wang, Rui Han, Zhou Fei, Bensheng Qiu, Weiping Li. Hypoxia inducible factor-1α expression is associated with hippocampal apoptosis during epileptogenesis. Brain research. vol 1590. 2015-07-09. PMID:25242614. |
moreover, the expression of hif-1α and hippocampal apoptosis presented significant time-dependent changes (p<0.01) within 2 weeks, and their positive correlation (p<0.05) analyzed by pearson׳s correlation analysis. |
2015-07-09 |
2023-08-13 |
rat |
Qianfa Long, Cairui Fan, Wang Kai, Qiang Luo, Weichuan Xin, Ping Wang, Ansheng Wang, Zhanyao Wang, Rui Han, Zhou Fei, Bensheng Qiu, Weiping Li. Hypoxia inducible factor-1α expression is associated with hippocampal apoptosis during epileptogenesis. Brain research. vol 1590. 2015-07-09. PMID:25242614. |
these results indicate that the hif-1α expression is associated with hippocampal apoptosis, and suggest that hif-1α is an important factor during epileptogenesis. |
2015-07-09 |
2023-08-13 |
rat |
Xiu-Li Jiang, Bo-Xiang Du, Jie Chen, Lin Liu, Wei-Bin Shao, Jie Son. MicroRNA-34a negatively regulates anesthesia-induced hippocampal apoptosis and memory impairment through FGFR1. International journal of clinical and experimental pathology. vol 7. issue 10. 2015-07-09. PMID:25400756. |
microrna-34a negatively regulates anesthesia-induced hippocampal apoptosis and memory impairment through fgfr1. |
2015-07-09 |
2023-08-13 |
mouse |
MuHuo Ji, Lin Dong, Min Jia, WenXue Liu, MingQiang Zhang, LinSha Ju, JiaoJiao Yang, Zhongcong Xie, JianJun Yan. Epigenetic enhancement of brain-derived neurotrophic factor signaling pathway improves cognitive impairments induced by isoflurane exposure in aged rats. Molecular neurobiology. vol 50. issue 3. 2015-07-08. PMID:24553857. |
our data showed that repeated isoflurane exposure significantly decreased the freezing time to context and the freezing time to tone in the fear conditioning test, which was associated with upregulated histone deacetylase 2, reduced histone acetylation, and increased inflammation and apoptosis in the hippocampus, and impairments of brain-derived neurotrophic factor (bdnf)-tyrosine kinase receptor b (trkb) and the downstream signaling pathway phospho-calmodulin-dependent protein kinase and phospho-camp response element-binding protein. |
2015-07-08 |
2023-08-12 |
rat |