| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bo Liu, Fei Li, Jingshan Shi, Danli Yang, Yuanyuan Deng, Qihai Gon. Gastrodin ameliorates subacute phase cerebral ischemia‑reperfusion injury by inhibiting inflammation and apoptosis in rats. Molecular medicine reports. vol 14. issue 5. 2017-04-10. PMID:27748849. |
2,3,5‑triphenyltetrazolium chloride staining was using to measure the infarct volume; morphological alterations were observed by hematoxylin and eosin staining under an optical microscope; apoptosis in the hippocampus and cortex was observed by terminal deoxynucleotidyl transferase dutp nick end labeling staining; and the level of mrna and protein expression was tested by reverse transcription‑quantitative polymerase chain reation and western blot analysis, respectively. |
2017-04-10 |
2023-08-13 |
rat |
| Zhi-Bin Zhou, Xiao-Yu Yang, Ying Tang, Xue Zhou, Li-Hua Zhou, Xia Fen. Subclinical concentrations of sevoflurane reduce oxidative stress but do not prevent hippocampal apoptosis. Molecular medicine reports. vol 14. issue 1. 2017-04-06. PMID:27222114. |
subclinical concentrations of sevoflurane reduce oxidative stress but do not prevent hippocampal apoptosis. |
2017-04-06 |
2023-08-13 |
rat |
| Zhi-Bin Zhou, Xiao-Yu Yang, Ying Tang, Xue Zhou, Li-Hua Zhou, Xia Fen. Subclinical concentrations of sevoflurane reduce oxidative stress but do not prevent hippocampal apoptosis. Molecular medicine reports. vol 14. issue 1. 2017-04-06. PMID:27222114. |
terminal deoxynucleotidyl-transferase dutp nick-end labeling staining was used to observe hippocampal neuronal apoptosis. |
2017-04-06 |
2023-08-13 |
rat |
| Zhi-Bin Zhou, Xiao-Yu Yang, Ying Tang, Xue Zhou, Li-Hua Zhou, Xia Fen. Subclinical concentrations of sevoflurane reduce oxidative stress but do not prevent hippocampal apoptosis. Molecular medicine reports. vol 14. issue 1. 2017-04-06. PMID:27222114. |
sevoflurane induced hippocampal apoptosis in a dose‑dependent manner and altered recognition memory testing indicated no differences among the groups. |
2017-04-06 |
2023-08-13 |
rat |
| Zhi-Bin Zhou, Xiao-Yu Yang, Ying Tang, Xue Zhou, Li-Hua Zhou, Xia Fen. Subclinical concentrations of sevoflurane reduce oxidative stress but do not prevent hippocampal apoptosis. Molecular medicine reports. vol 14. issue 1. 2017-04-06. PMID:27222114. |
although early exposure to a subclinical concentration of sevoflurane reduced oxidative stress, it did not prevent the process of sevoflurane-induced hippocampal apoptosis. |
2017-04-06 |
2023-08-13 |
rat |
| Yujie Wang, Changyi Wu, Bin Han, Fei Xu, Mingfeng Mao, Xiangyang Guo, Jun Wan. Dexmedetomidine attenuates repeated propofol exposure-induced hippocampal apoptosis, PI3K/Akt/Gsk-3β signaling disruption, and juvenile cognitive deficits in neonatal rats. Molecular medicine reports. vol 14. issue 1. 2017-04-06. PMID:27222147. |
dexmedetomidine attenuates repeated propofol exposure-induced hippocampal apoptosis, pi3k/akt/gsk-3β signaling disruption, and juvenile cognitive deficits in neonatal rats. |
2017-04-06 |
2023-08-13 |
rat |
| Yaqiong Zhang, Zhihua Cheng, Changli Wang, Hongda Ma, Weihong Meng, Qingchun Zha. Neuroprotective Effects of Kukoamine a against Radiation-induced Rat Brain Injury through Inhibition of Oxidative Stress and Neuronal Apoptosis. Neurochemical research. vol 41. issue 10. 2017-04-04. PMID:27241194. |
tunel staining was performed to detect the level of apoptosis in hippocampal neurons. |
2017-04-04 |
2023-08-13 |
rat |
| Yanan Zhang, Dongliang Li, Haiou Li, Dailiang Hou, Jingdong Ho. Taurine Pretreatment Prevents Isoflurane-Induced Cognitive Impairment by Inhibiting ER Stress-Mediated Activation of Apoptosis Pathways in the Hippocampus in Aged Rats. Neurochemical research. vol 41. issue 10. 2017-04-04. PMID:27255599. |
taurine pretreatment prevents isoflurane-induced cognitive impairment by inhibiting er stress-mediated activation of apoptosis pathways in the hippocampus in aged rats. |
2017-04-04 |
2023-08-13 |
rat |
| Yanan Zhang, Dongliang Li, Haiou Li, Dailiang Hou, Jingdong Ho. Taurine Pretreatment Prevents Isoflurane-Induced Cognitive Impairment by Inhibiting ER Stress-Mediated Activation of Apoptosis Pathways in the Hippocampus in Aged Rats. Neurochemical research. vol 41. issue 10. 2017-04-04. PMID:27255599. |
compared with control, isoflurane increased expression of hippocampal er stress biomarkers including glucose-regulated protein 78, phosphorylated (p-) inositol-requiring enzyme 1, p-eukaryotic initiation factor 2-α (eif2α), activating transcription factor 4 (atf-4), cleaved atf-6 and c/ebp homologous protein, along with activation of apoptosis pathways as indicated by decreased b cell lymphoma 2 (bcl-2)/bcl2-associated x protein, increased expressions of cytochrome-c and cleaved caspase-3. |
2017-04-04 |
2023-08-13 |
rat |
| Yanan Zhang, Dongliang Li, Haiou Li, Dailiang Hou, Jingdong Ho. Taurine Pretreatment Prevents Isoflurane-Induced Cognitive Impairment by Inhibiting ER Stress-Mediated Activation of Apoptosis Pathways in the Hippocampus in Aged Rats. Neurochemical research. vol 41. issue 10. 2017-04-04. PMID:27255599. |
the results indicate that taurine pretreatment prevents anesthetic isoflurane-induced cognitive impairment by inhibiting er stress-mediated activation of apoptosis pathways in the hippocampus in aged rats. |
2017-04-04 |
2023-08-13 |
rat |
| Zhenwei Li, Qi Liu, Chang Liu, Chunna Li, Yachen Li, Shuangyue Li, Xiaohui Liu, Jing Sha. Evaluation of PFOS-mediated neurotoxicity in rat primary neurons and astrocytes cultured separately or in co-culture. Toxicology in vitro : an international journal published in association with BIBRA. vol 38. 2017-03-29. PMID:27825932. |
exposure of rat primary hippocampal neurons to pfos has led to oxidation-antioxidation imbalance, increased apoptosis and abnormal autophagy. |
2017-03-29 |
2023-08-13 |
rat |
| b' Milo\\xc5\\xa1 Stanojlovi\\xc4\\x87, Ivana Gu\\xc5\\xa1evac, Ivana Grkovi\\xc4\\x87, Nata\\xc5\\xa1a Mitrovi\\xc4\\x87, Jelena Zlatkovi\\xc4\\x87, Anica Horvat, Dunja Drakuli\\xc4\\x8. Repeated Estradiol Treatment Attenuates Chronic Cerebral Hypoperfusion-Induced Neurodegeneration in Rat Hippocampus. Cellular and molecular neurobiology. vol 36. issue 6. 2017-03-22. PMID:26689702.' |
the present study attempted to verify whether post-ischemic estradiol treatment (33.3 μg/kg for seven consecutive days) affects previously reported number of hippocampal apoptotic cells and amount of dna fragmentation characteristic for apoptosis as well as the expression of key elements within synaptosomal akt and erk signal transduction pathways (nf-κb, bax, bcl-2, cytochrome c, caspase 3, and parp). |
2017-03-22 |
2023-08-13 |
rat |
| Hong-Yan Gong, Fang Zheng, Chao Zhang, Xi-Yan Chen, Jing-Jing Liu, Xiu-Qin Yu. Propofol protects hippocampal neurons from apoptosis in ischemic brain injury by increasing GLT-1 expression and inhibiting the activation of NMDAR via the JNK/Akt signaling pathway. International journal of molecular medicine. vol 38. issue 3. 2017-03-21. PMID:27430327. |
propofol protects hippocampal neurons from apoptosis in ischemic brain injury by increasing glt-1 expression and inhibiting the activation of nmdar via the jnk/akt signaling pathway. |
2017-03-21 |
2023-08-13 |
Not clear |
| Hong-Yan Gong, Fang Zheng, Chao Zhang, Xi-Yan Chen, Jing-Jing Liu, Xiu-Qin Yu. Propofol protects hippocampal neurons from apoptosis in ischemic brain injury by increasing GLT-1 expression and inhibiting the activation of NMDAR via the JNK/Akt signaling pathway. International journal of molecular medicine. vol 38. issue 3. 2017-03-21. PMID:27430327. |
cell viability assay and apoptosis assay were performed to examine the neuroprotective effects of propofol on hippocampal neurons in ibi. |
2017-03-21 |
2023-08-13 |
Not clear |
| Hong-Yan Gong, Fang Zheng, Chao Zhang, Xi-Yan Chen, Jing-Jing Liu, Xiu-Qin Yu. Propofol protects hippocampal neurons from apoptosis in ischemic brain injury by increasing GLT-1 expression and inhibiting the activation of NMDAR via the JNK/Akt signaling pathway. International journal of molecular medicine. vol 38. issue 3. 2017-03-21. PMID:27430327. |
the sirna-mediated knockdown of glt‑1 in the hypoxia-exposed hippocampal neuronal cells led to an increase in cell apoptosis, jun n-terminal kinase (jnk) activation and n-methyl-d‑aspartate (nmda) receptor (nr1 and nr2b) activation, as well as to a decrease in cell viability and a decrease in akt activation. |
2017-03-21 |
2023-08-13 |
Not clear |
| Hong-Yan Gong, Fang Zheng, Chao Zhang, Xi-Yan Chen, Jing-Jing Liu, Xiu-Qin Yu. Propofol protects hippocampal neurons from apoptosis in ischemic brain injury by increasing GLT-1 expression and inhibiting the activation of NMDAR via the JNK/Akt signaling pathway. International journal of molecular medicine. vol 38. issue 3. 2017-03-21. PMID:27430327. |
the effects of rna interference-mediated glt‑1 gene silencing on cell viability, jnk activation, nmdar activation, cell apoptosis and akt activation in the hippocampal neuronal cells were slightly reversed by propofol treatment. |
2017-03-21 |
2023-08-13 |
Not clear |
| Hong-Yan Gong, Fang Zheng, Chao Zhang, Xi-Yan Chen, Jing-Jing Liu, Xiu-Qin Yu. Propofol protects hippocampal neurons from apoptosis in ischemic brain injury by increasing GLT-1 expression and inhibiting the activation of NMDAR via the JNK/Akt signaling pathway. International journal of molecular medicine. vol 38. issue 3. 2017-03-21. PMID:27430327. |
the jnk agonist, anisomycin, and the akt inhibitor, ly294002, both significantly blocked the effects of propofol on hippocampal neuronal cell viability and apoptosis in ibi. |
2017-03-21 |
2023-08-13 |
Not clear |
| Yu-Qing Li, Zoey Cheng, Shun Won. Differential Apoptosis Radiosensitivity of Neural Progenitors in Adult Mouse Hippocampus. International journal of molecular sciences. vol 17. issue 5. 2017-03-16. PMID:27331809. |
differential apoptosis radiosensitivity of neural progenitors in adult mouse hippocampus. |
2017-03-16 |
2023-08-13 |
mouse |
| Yu-Qing Li, Zoey Cheng, Shun Won. Differential Apoptosis Radiosensitivity of Neural Progenitors in Adult Mouse Hippocampus. International journal of molecular sciences. vol 17. issue 5. 2017-03-16. PMID:27331809. |
neural progenitors in dentate gyrus of the hippocampus are known to undergo apoptosis after irradiation. |
2017-03-16 |
2023-08-13 |
mouse |
| Yu-Qing Li, Zoey Cheng, Shun Won. Differential Apoptosis Radiosensitivity of Neural Progenitors in Adult Mouse Hippocampus. International journal of molecular sciences. vol 17. issue 5. 2017-03-16. PMID:27331809. |
using a mouse model of hippocampal neuronal development, we characterized the apoptosis sensitivity of the different neural progenitor subpopulations in adult mouse dentate gyrus after irradiation. |
2017-03-16 |
2023-08-13 |
mouse |