| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Takeshi Tanaka, Hajime Abe, Masayuki Kimura, Nobuhiko Onda, Sayaka Mizukami, Toshinori Yoshida, Makoto Shibutan. Developmental exposure to T-2 toxin reversibly affects postnatal hippocampal neurogenesis and reduces neural stem cells and progenitor cells in mice. Archives of toxicology. vol 90. issue 8. 2017-03-02. PMID:26314264. |
in the hippocampal dentate gyrus of male pnd 21 offspring, gfap(+) and blbp(+) type-1 stem cells and pax6(+) and tbr2(+) type-2 progenitor cells decreased in the subgranular zone (sgz) at 9 and ≥3 ppm, respectively, in parallel with increased apoptosis at ≥3 ppm. |
2017-03-02 |
2023-08-13 |
mouse |
| You-Fa Zhou, Qing-Xia Wang, Hai-Yan Zhou, Gang Che. Autophagy activation prevents sevoflurane-induced neurotoxicity in H4 human neuroglioma cells. Acta pharmacologica Sinica. vol 37. issue 5. 2017-02-28. PMID:27041458. |
previous study has shown that sevoflurane triggers er stress and may lead to apoptosis in rat hippocampal neurons. |
2017-02-28 |
2023-08-13 |
human |
| Bodo C Melni. Apoptosis May Explain the Pharmacological Mode of Action and Adverse Effects of Isotretinoin, Including Teratogenicity. Acta dermato-venereologica. vol 97. issue 2. 2017-02-28. PMID:27671426. |
furthermore, apoptosis may be the underlying and unifying mechanism of the adverse effects of isotretinoin on neural crest cells (teratogenicity), hippocampal neurones (depression), epidermal keratinocytes and mucosa cells (mucocutaneous side-effects), hair follicle cells (telogen effluvium), intestinal epithelial cells (inflammatory bowel disease), skeletal muscle cells (myalgia and release of creatine kinase), and hepatocytes (release of transaminases and very low-density lipoproteins). |
2017-02-28 |
2023-08-13 |
Not clear |
| Yang Zhao, Ying Han, Ding-Fang Bu, Jing Zhang, Qin-Rui Li, Hong-Fang Jin, Jun-Bao Du, Jiong Qi. Reduced AKT phosphorylation contributes to endoplasmic reticulum stress-mediated hippocampal neuronal apoptosis in rat recurrent febrile seizure. Life sciences. vol 153. 2017-02-27. PMID:27084529. |
reduced akt phosphorylation contributes to endoplasmic reticulum stress-mediated hippocampal neuronal apoptosis in rat recurrent febrile seizure. |
2017-02-27 |
2023-08-13 |
rat |
| Xiaoming Zhang, Youfa Zhou, Mingmin Xu, Gang Che. Autophagy Is Involved in the Sevoflurane Anesthesia-Induced Cognitive Dysfunction of Aged Rats. PloS one. vol 11. issue 4. 2017-02-21. PMID:27111854. |
similar effects have been found in aged rats under sevoflurane anesthesia; however, the role of autophagy in sevoflurane anesthesia-induced hippocampal neuron apoptosis of older rats remains elusive. |
2017-02-21 |
2023-08-13 |
rat |
| Xiaoming Zhang, Youfa Zhou, Mingmin Xu, Gang Che. Autophagy Is Involved in the Sevoflurane Anesthesia-Induced Cognitive Dysfunction of Aged Rats. PloS one. vol 11. issue 4. 2017-02-21. PMID:27111854. |
the results demonstrated that sevoflurane anesthesia significantly impaired memory performance and induced hippocampal neuron apoptosis. |
2017-02-21 |
2023-08-13 |
rat |
| Leonie von Elsner, Sandra Hagemann, Ingo Just, Astrid Rohrbec. C3 exoenzyme impairs cell proliferation and apoptosis by altering the activity of transcription factors. Naunyn-Schmiedeberg's archives of pharmacology. vol 389. issue 9. 2017-02-21. PMID:27351882. |
previous studies of our group with the murine hippocampal cell line ht22 revealed a c3-mediated inhibition of cell proliferation after 48 h and a prevention of serum-starved cells from apoptosis. |
2017-02-21 |
2023-08-13 |
Not clear |
| Chun-Mei Wang, Xiao-Lan Cai, Qing-Ping We. Astaxanthin reduces isoflurane-induced neuroapoptosis via the PI3K/Akt pathway. Molecular medicine reports. vol 13. issue 5. 2017-02-17. PMID:27035665. |
furthermore, isoflurane suppressed cell growth, induced cell apoptosis, enhanced caspase‑3 activity and downregulated the pi3k/akt pathway in organotypic hippocampal slice culture. |
2017-02-17 |
2023-08-13 |
rat |
| Bin Chen, Ying Teng, Xingguang Zhang, Xiaofeng Lv, Yanling Yi. Metformin Alleviated Aβ-Induced Apoptosis via the Suppression of JNK MAPK Signaling Pathway in Cultured Hippocampal Neurons. BioMed research international. vol 2016. 2017-02-14. PMID:27403417. |
metformin alleviated aβ-induced apoptosis via the suppression of jnk mapk signaling pathway in cultured hippocampal neurons. |
2017-02-14 |
2023-08-13 |
Not clear |
| Mohsen Alipour, Fatemeh Adineh, Hossein Mosatafavi, Azam Aminabadi, Hananeh Monirinasab, Mohammad Reza Jafar. Effect of chronic intraperitoneal aminoguanidine on memory and expression of Bcl-2 family genes in diabetic rats. Canadian journal of physiology and pharmacology. vol 94. issue 6. 2017-02-13. PMID:27210113. |
injections of ag on passive avoidance learning (pal) and hippocampal apoptosis in rat. |
2017-02-13 |
2023-08-13 |
rat |
| J C Zhang, W Lu, X M Xie, H Pan, Z Q Wu, G T Yan. Mild hypothermia attenuates post-resuscitation brain injury through a V-ATPase mechanism in a rat model of cardiac arrest. Genetics and molecular research : GMR. vol 15. issue 2. 2017-02-10. PMID:27323115. |
these findings suggested that mild hypothermia inhibits ca-induced apoptosis in the hippocampus, which may be associated with reduced v-atpase impairment. |
2017-02-10 |
2023-08-13 |
rat |
| Shaojun Wang, Jun Zhou, Weijie Kang, Zhaoni Dong, Hezuo Wan. Tocilizumab inhibits neuronal cell apoptosis and activates STAT3 in cerebral infarction rat model. Bosnian journal of basic medical sciences. vol 16. issue 2. 2017-02-09. PMID:26773188. |
cell apoptosis in hippocampus and cortex of the brain was examined with tunel method. |
2017-02-09 |
2023-08-13 |
rat |
| Xiangren Zheng, Yan Sun, Lulu Ke, Wei Ouyang, Zigui Zhan. Molecular mechanism of brain impairment caused by drinking-acquired fluorosis and selenium intervention. Environmental toxicology and pharmacology. vol 43. 2017-02-09. PMID:26991847. |
thus, the mitochondrial cytc-caspase-9-caspase-3 apoptosis pathway in the hippocampus was one of the mechanisms leading to fluorosis-induced brain damage. |
2017-02-09 |
2023-08-13 |
rat |
| Enrica Bianchi, Lorenzo Di Cesare Mannelli, Laura Micheli, Mersedez Farzad, Margherita Aglianò, Carla Ghelardin. Apoptotic Process Induced by Oxaliplatin in Rat Hippocampus Causes Memory Impairment. Basic & clinical pharmacology & toxicology. vol 120. issue 1. 2017-02-08. PMID:27273873. |
apoptosis rate significantly increased in cultured hippocampal cells exposed to ox at increasing doses, and this effect was dose-dependent. |
2017-02-08 |
2023-08-13 |
rat |
| Enrica Bianchi, Lorenzo Di Cesare Mannelli, Laura Micheli, Mersedez Farzad, Margherita Aglianò, Carla Ghelardin. Apoptotic Process Induced by Oxaliplatin in Rat Hippocampus Causes Memory Impairment. Basic & clinical pharmacology & toxicology. vol 120. issue 1. 2017-02-08. PMID:27273873. |
ex vivo experiments showed that cell damage and apoptosis were blocked in the hippocampus from ox rats cotreated with copper sulphate (cs) which precludes ox transport inside the cell. |
2017-02-08 |
2023-08-13 |
rat |
| A Molahosseini, M M Taghavi, Z Taghipour, A Shabanizadeh, F Fatehi, M Kazemi Arababadi, S H Eftekhar Vaghef. The effect of the ginger on the apoptosis of hippochampal cells according to the expression of BAX and Cyclin D1 genes and histological characteristics of brain in streptozotocin male diabetic rats. Cellular and molecular biology (Noisy-le-Grand, France). vol 62. issue 12. 2017-02-08. PMID:27894393. |
the aim of the present study was to determine the effect of ginger extract on apoptosis of the neurons of hippocampus, via evaluation of bax and cyclin d1 and also histological analysis, in male diabetic rats. |
2017-02-08 |
2023-08-13 |
rat |
| A Molahosseini, M M Taghavi, Z Taghipour, A Shabanizadeh, F Fatehi, M Kazemi Arababadi, S H Eftekhar Vaghef. The effect of the ginger on the apoptosis of hippochampal cells according to the expression of BAX and Cyclin D1 genes and histological characteristics of brain in streptozotocin male diabetic rats. Cellular and molecular biology (Noisy-le-Grand, France). vol 62. issue 12. 2017-02-08. PMID:27894393. |
this means that the ginger may protects neurons of the hippocampus from apoptosis in diabetic patients. |
2017-02-08 |
2023-08-13 |
rat |
| Chunchun Yin, Xiaoping Luo, Yuqing Duan, Wenyi Duan, Haihui Zhang, Yuanqing He, Guibo Sun, Xiaobo Su. Neuroprotective effects of lotus seedpod procyanidins on extremely low frequency electromagnetic field-induced neurotoxicity in primary cultured hippocampal neurons. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 82. 2017-02-07. PMID:27470406. |
in addition, supplementation with lspcs could alleviate dna damage, block cell cycle arrest at s phase, and inhibit apoptosis and necrosis of hippocampal neurons under elf-emf exposure. |
2017-02-07 |
2023-08-13 |
rat |
| Arpita Sharma, Nisha Patro, Ishan K Patr. Lipopolysaccharide-Induced Apoptosis of Astrocytes: Therapeutic Intervention by Minocycline. Cellular and molecular neurobiology. vol 36. issue 4. 2017-02-06. PMID:26188416. |
the present study suggests that the lipopolysaccharide (lps)-induced inflammation results in significant astrocytic apoptosis compared to other cell types in hippocampus and minocycline could not efficiently restrict the glutamate-mediated toxicity and apoptosis of astrocytes. |
2017-02-06 |
2023-08-13 |
rat |
| Chaonan Fan, Wenfei Sun, Huicong Fu, Hua Dong, Lulu Xia, Yuanyuan Lu, Richard J Deckelbaum, Kemin Q. DIETARY RATIOS OF N-6/N-3 POLYUNSATURATED FATTY ACIDS DURING MATERNAL PREGNANCY AFFECT HIPPOCAMPAL NEUROGENESIS AND APOPTOSIS IN MOUSE OFFSPRING. Nutricion hospitalaria. vol 32. issue 3. 2017-02-06. PMID:26319835. |
dietary ratios of n-6/n-3 polyunsaturated fatty acids during maternal pregnancy affect hippocampal neurogenesis and apoptosis in mouse offspring. |
2017-02-06 |
2023-08-13 |
mouse |