| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ying Huang, Xiangping Liao, Huaiwei Wang, Jianghong Luo, Shanquan Zhong, Ziliang Zhang, Fang Zhang, Jianping Chen, Fuhua Xi. Effects of imperatorin on apoptosis and synaptic plasticity in vascular dementia rats. Scientific reports. vol 11. issue 1. 2021-11-12. PMID:33883654. |
we revealed that 2vo-induced cognitive impairment, hippocampus ca1 neuron damage, apoptosis and synaptic damage. |
2021-11-12 |
2023-08-13 |
rat |
| Golshad Kowsari, Soraya Mehrabi, Sara Soleimani Asl, Mahsa Pourhamzeh, Kazem Mousavizadeh, Mehdi Mehdizade. Nicotine and modafinil combination protects against the neurotoxicity induced by 3,4-Methylenedioxymethamphetamine in hippocampal neurons of male rats. Journal of chemical neuroanatomy. vol 116. 2021-11-10. PMID:34119664. |
by tunel test and cresyl violet staining we evaluated neuronal loss and apoptosis in the hippocampal ca1 and found increased neuronal viability in the nmc group. |
2021-11-10 |
2023-08-13 |
rat |
| Caitlin A Finney, Artur Shvetcov, R Frederick Westbrook, Margaret J Morris, Nicole M Jone. The selective estrogen receptor modulator tamoxifen protects against subtle cognitive decline and early markers of injury 24 h after hippocampal silent infarct in male Sprague-Dawley rats. Hormones and behavior. vol 134. 2021-11-01. PMID:34242875. |
we induced si in the dorsal hippocampal ca1 of rats and assessed whether tamoxifen is protective 24 h later against cognitive deficits and injury responses including gliosis, apoptosis, inflammation and changes in estrogen receptors (ers). |
2021-11-01 |
2023-08-13 |
rat |
| Caitlin A Finney, Artur Shvetcov, R Frederick Westbrook, Margaret J Morris, Nicole M Jone. The selective estrogen receptor modulator tamoxifen protects against subtle cognitive decline and early markers of injury 24 h after hippocampal silent infarct in male Sprague-Dawley rats. Hormones and behavior. vol 134. 2021-11-01. PMID:34242875. |
tamoxifen mitigates apoptosis, gliosis, and inflammation and normalization of er levels in the ca1, leading to improved cognitive outcomes after hippocampal si. |
2021-11-01 |
2023-08-13 |
rat |
| Jie Shen, Ping Zhang, Ye Li, Cuiqin Fan, Tian Lan, Wenjing Wang, Shu Yan Y. Neuroprotective effects of microRNA-211-5p on chronic stress-induced neuronal apoptosis and depression-like behaviours. Journal of cellular and molecular medicine. vol 25. issue 14. 2021-10-05. PMID:34121317. |
when mir-211-5p was up-regulated in these rats, neuronal apoptosis within the ca1 area was suppressed, effects which were accompanied with an amelioration of depression-like behaviours in these rats. |
2021-10-05 |
2023-08-13 |
rat |
| Jie Shen, Ping Zhang, Ye Li, Cuiqin Fan, Tian Lan, Wenjing Wang, Shu Yan Y. Neuroprotective effects of microRNA-211-5p on chronic stress-induced neuronal apoptosis and depression-like behaviours. Journal of cellular and molecular medicine. vol 25. issue 14. 2021-10-05. PMID:34121317. |
in further support of this proposal are the findings that knock-down of mir-211-5p within the ca1 area of normal rats activated the dyrk1a/ask1/jnk pathway, resulting in the promotion of neuronal apoptosis and display of depression-like behaviours in these rats. |
2021-10-05 |
2023-08-13 |
rat |
| Manish Shukla, Kumar Vyonkesh Mani, Deepshikha, Sangeeta Shukla, Neeru Kapoo. Moderate noise associated oxidative stress with concomitant memory impairment, neuro-inflammation and neurodegeneration. Brain, behavior, & immunity - health. vol 5. 2021-10-01. PMID:34589861. |
further, the underlying mechanism pertaining to apoptosis was investigated by immuno-histological studies through assessment of caspase-3 and tunel assay as well as morphological parameters, namely nissl bodies in ca1, ca3 and dg regions of hippocampus. |
2021-10-01 |
2023-08-13 |
rat |
| Raheleh Rafaiee, Hosein Khastar, Behzad Garmabi, Malihe Taleb, Pirasteh Norouzi, Mehdi Khaksar. Hydrogen sulfide protects hippocampal CA1 neurons against lead mediated neuronal damage via reduction oxidative stress in male rats. Journal of chemical neuroanatomy. vol 112. 2021-09-30. PMID:33444772. |
h2s treatment suppressed pb-related apoptosis in the hippocampal ca1 subfield (p<0.01). |
2021-09-30 |
2023-08-13 |
rat |
| Qingtong Zhang, Jiangwen Yin, Feng Xu, Jingwen Zhai, Jieting Yin, Mingyue Ge, Wenyi Zhou, Nian Li, Xinlei Qin, Yan Li, Sheng Wan. Isoflurane post-conditioning contributes to anti-apoptotic effect after cerebral ischaemia in rats through the ERK5/MEF2D signaling pathway. Journal of cellular and molecular medicine. vol 25. issue 8. 2021-09-22. PMID:33621420. |
we measured the expression of mef2d, erk5, gfap and caspase-3 by immunofluorescent staining and western blotting, and tunel staining to assess the severity of apoptosis in hippocampal ca1 area. |
2021-09-22 |
2023-08-13 |
rat |
| Serpil Ünver Saraydin, Berna Özdenoglu Kutlu, Dursun Saraydı. Effects of diabetes on apoptosis and mitosis in rat hippocampus. Biotechnic & histochemistry : official publication of the Biological Stain Commission. vol 96. issue 6. 2021-09-17. PMID:32938250. |
we investigated the effects of diabetes on apoptosis and mitosis in the hippocampal ca1 region. |
2021-09-17 |
2023-08-13 |
rat |
| Serpil Ünver Saraydin, Berna Özdenoglu Kutlu, Dursun Saraydı. Effects of diabetes on apoptosis and mitosis in rat hippocampus. Biotechnic & histochemistry : official publication of the Biological Stain Commission. vol 96. issue 6. 2021-09-17. PMID:32938250. |
we investigated caspase-3, caspase-7 and ki 67 levels immunohistochemically for mitotic activity, the tunel method for apoptosis and gfap for astrocyte cell density in the hippocampal ca1 region. |
2021-09-17 |
2023-08-13 |
rat |
| Serpil Ünver Saraydin, Berna Özdenoglu Kutlu, Dursun Saraydı. Effects of diabetes on apoptosis and mitosis in rat hippocampus. Biotechnic & histochemistry : official publication of the Biological Stain Commission. vol 96. issue 6. 2021-09-17. PMID:32938250. |
diabetes stimulates apoptosis and promotes cell proliferation in the hippocampal ca1 region, which may impair its homeostasis and function. |
2021-09-17 |
2023-08-13 |
rat |
| Alireza Torfeh, Zohreh Abdolmaleki, Sepideh Nazarian, Seyed Hamed Shirazi Beheshtih. Modafinil-coated nanoparticle increases expressions of brain-derived neurotrophic factor, glial cell line-derived neurotrophic factor and neuronal nuclear protein, and protects against middle cerebral artery occlusion-induced neuron apoptosis in the rat hippocampus. Anatomical record (Hoboken, N.J. : 2007). vol 304. issue 9. 2021-09-03. PMID:33345406. |
this study's results showed that the use of modafinil-coated nanoparticle has neuroprotective effects by increasing neurotrophic factors and reducing apoptosis after mcao in the ca1 area of the hippocampus. |
2021-09-03 |
2023-08-13 |
human |
| Shabnam Movassaghi, Zeinab Khazaei Koohpar, Mehrdad Hashemi, Sourena Jafari Semnani, Zahra Nadia Sharif. Neuroprotective Effect of Pentoxifylline on 3,4-Methylenedioxymethamphetamine-Induced Apoptosis in CA1 Cells of Wistar Rat Hippocampus. Galen medical journal. vol 8. 2021-09-03. PMID:34466455. |
neuroprotective effect of pentoxifylline on 3,4-methylenedioxymethamphetamine-induced apoptosis in ca1 cells of wistar rat hippocampus. |
2021-09-03 |
2023-08-13 |
rat |
| I V Kastyro, I V Reshetov, G V Khamidulin, S S Shilin, V I Torshin, M G Kostyaeva, V I Popadyuk, T Y Yunusov, P E Shmaevsky, K P Shalamov, A D Kupryakova, E S Doroginskaya, A D Sedelnikov. Influence of Surgical Trauma in the Nasal Cavity on the Expression of p53 Protein in the Hippocampus of Rats. Doklady. Biochemistry and biophysics. vol 497. issue 1. 2021-08-13. PMID:33895923. |
a quantitative assessment of the apoptosis of neurons in the pyramidal layer of the hippocampus in the subfields ca1, ca2, ca3, and dentate gyrus (dg) on days 2, 4, and 6 after surgery was carried out. |
2021-08-13 |
2023-08-13 |
rat |
| Duk-Shin Lee, Ji-Eun Ki. Regional specific activations of ERK1/2 and CDK5 differently regulate astroglial responses to ER stress in the rat hippocampus following status epilepticus. Brain research. vol 1753. 2021-07-22. PMID:33422538. |
salubrinal (an er stress inhibitor) abrogated activations of erk1/2 and cdk5, and attenuated reactive astrogliosis in the ca1 region and astroglial apoptosis in the molecular layer of the dentate gyrus following status epilepticus (se, a prolonged seizure activity). |
2021-07-22 |
2023-08-13 |
rat |
| Libo Chuan, Xin Huang, Chuming Fan, Shiyuan Wen, Xiaohua Yang, Jingrong Wang, Jingyu Ren, Jin Ru, Li Din. Metformin ameliorates brain damage caused by cardiopulmonary resuscitation via targeting endoplasmic reticulum stress-related proteins GRP78 and XBP1. European journal of pharmacology. vol 891. 2021-05-19. PMID:33197442. |
moreover, our results showed that the rats treated with metformin had increased neurological deficit scores (nds), an improved seven-day survival rate, decreased cell apoptosis within the hippocampus ca1 area, and less oxidative stress compared with the ca/cpr group. |
2021-05-19 |
2023-08-13 |
rat |
| Ji-Eun Kim, Hana Park, Tae-Hyun Kim, Tae-Cheon Kan. LONP1 Regulates Mitochondrial Accumulations of HMGB1 and Caspase-3 in CA1 and PV Neurons Following Status Epilepticus. International journal of molecular sciences. vol 22. issue 5. 2021-04-16. PMID:33668863. |
on the other hand, translocation of high mobility group box 1 (hmgb1) and active caspase-3 into mitochondria is involved in apoptosis of parvalbumin (pv) cells (one of the gabaergic interneurons) and necrosis of ca1 neurons in the rat hippocampus, respectively, following status epilepticus (se). |
2021-04-16 |
2023-08-13 |
rat |
| A González-Maciel, R M Romero-Velázquez, A Alfaro-Rodríguez, P Sanchez Aparicio, R Reynoso-Roble. Prenatal exposure to oxcarbazepine increases hippocampal apoptosis in rat offspring. Journal of chemical neuroanatomy. vol 103. 2021-03-23. PMID:31794794. |
apoptosis was detected at three postnatal ages using the tunel technique in the ca1, and ca3 regions of the hippocampus and in the dentate gyrus (dg); neurogenesis was assessed in the dg using an antibody against doublecortin. |
2021-03-23 |
2023-08-13 |
rat |
| Tsong-Hai Lee, Jen-Tsung Yang, Jr-Rung Lin, Chaur-Jong Hu, Wen-Hai Chou, Ching-Po Lin, Nai-Fang Ch. Protective effects of ischemic preconditioning against neuronal apoptosis and dendritic injury in the hippocampus are age-dependent. Journal of neurochemistry. vol 155. issue 4. 2021-03-10. PMID:32314365. |
the 15-min ischemia-induced significant delayed neuronal apoptosis and early dendritic injury evidenced by dti and map2 studies in both ca1 and dg areas with more severe injury in middle-aged gerbils than adult gerbils. |
2021-03-10 |
2023-08-13 |
Not clear |