| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Boris Görg, Hans-Jürgen Bidmon, Dieter Häussinge. Gene expression profiling in the cerebral cortex of patients with cirrhosis with and without hepatic encephalopathy. Hepatology (Baltimore, Md.). vol 57. issue 6. 2013-08-16. PMID:23325665. |
genes with altered expression pattern in he were related to oxidative stress, microglia activation, receptor signaling, inflammatory pathways, cell proliferation, and apoptosis. |
2013-08-16 |
2023-08-12 |
human |
| Xuqing Liu, Huanxing Su, Tak-Ho Chu, Anchen Guo, Wutian W. Minocycline inhibited the pro-apoptotic effect of microglia on neural progenitor cells and protected their neuronal differentiation in vitro. Neuroscience letters. vol 542. 2013-08-15. PMID:23518153. |
then microglia were activated with lipopolysaccharide (lps) or treated with lps plus minocycline (lpsmc), and the effects of conditioned media on npc apoptosis and differentiation were studied. |
2013-08-15 |
2023-08-12 |
Not clear |
| Li Zhang, Lian-Yan Dong, Ya-Jian Li, Zhen Hong, Wen-Shi We. miR-21 represses FasL in microglia and protects against microglia-mediated neuronal cell death following hypoxia/ischemia. Glia. vol 60. issue 12. 2013-08-05. PMID:22907769. |
the overproduction of fasl following hypoxic microglial activation induced neuronal apoptosis, whereas the ectopic expression of mir-21 partially protected neurons from cell death caused by hypoxia-activated microglia. |
2013-08-05 |
2023-08-12 |
human |
| Ya-Fang He, Hui-Jin Chen, Long-Hua Qian, Liu-Fang He, Jeffrey S Buzb. Diphenyleneiodonium protects preoligodendrocytes against endotoxin-activated microglial NADPH oxidase-generated peroxynitrite in a neonatal rat model of periventricular leukomalacia. Brain research. vol 1492. 2013-07-22. PMID:23174417. |
in vitro, preols co-cultured with microglia exhibited increased preol apoptosis, accompanied by overproduction of superoxide anion (o(2)(-)) and the formation of peroxynitrite (onoo(-)) after lps exposure. |
2013-07-22 |
2023-08-12 |
rat |
| Jingnan Pu, Wei Shi, Zizhang Wang, Ruizhi Wang, Zhenyu Guo, Chongxiao Liu, Jianjun Sun, Ligui Gao, Ren Zho. Effects of minocycline on the expression of NGF and HSP70 and its neuroprotection role following intracerebral hemorrhage in rats. Journal of biomedical research. vol 25. issue 4. 2013-07-04. PMID:23554704. |
mc may inhibit the activation of microglia, the inflammatory reaction and factors, matrix metalloproteinases and apoptosis, thus protecting neurons. |
2013-07-04 |
2023-08-12 |
rat |
| Xiaoshuang Jiang, Yingqin Ni, Tianjin Liu, Meng Zhang, Hui Ren, Gezhi X. Inhibition of LPS-induced retinal microglia activation by naloxone does not prevent photoreceptor death. Inflammation. vol 36. issue 1. 2013-07-03. PMID:22869199. |
flow cytometry analysis of annexin v/propidium iodide staining showed that lps-activated microglia promoted the apoptosis of co-cultured 661 w photoreceptor cells. |
2013-07-03 |
2023-08-12 |
Not clear |
| Masaki Ueno, Yuki Fujita, Tatsuhide Tanaka, Yuka Nakamura, Junichi Kikuta, Masaru Ishii, Toshihide Yamashit. Layer V cortical neurons require microglial support for survival during postnatal development. Nature neuroscience. vol 16. issue 5. 2013-06-27. PMID:23525041. |
inactivation of microglia by minocycline treatment or transient ablation of microglia in cd11b-dtr transgenic mice led to increased apoptosis, specifically in layer v subcerebral and callosal projection neurons. |
2013-06-27 |
2023-08-12 |
mouse |
| Yiying Wu, Leisi Bian, Xiushi Ni, Min Ning, Yanling Zhao, Rujing Lin. A mechanistic investigation into non-infarcted brain injury induced by cerebral artery microemboli. Molecular biology reports. vol 40. issue 2. 2013-06-17. PMID:23129315. |
injection of 25-50 μm microemboli at a dose of 100 microemboli in 300 μl into the carotid artery of rats did not result in cerebral infarction, but led to neuronal apoptosis, hyperplasia and activation of microglia and astrocytes. |
2013-06-17 |
2023-08-12 |
rat |
| Yee Andy Yeo, Julia M Martínez Gómez, J Ludovic Croxford, Stephan Gasser, Eng-Ang Ling, Herbert Schwar. CD137 ligand activated microglia induces oligodendrocyte apoptosis via reactive oxygen species. Journal of neuroinflammation. vol 9. 2013-06-10. PMID:22799524. |
cd137 ligand activated microglia induces oligodendrocyte apoptosis via reactive oxygen species. |
2013-06-10 |
2023-08-12 |
mouse |
| Yee Andy Yeo, Julia M Martínez Gómez, J Ludovic Croxford, Stephan Gasser, Eng-Ang Ling, Herbert Schwar. CD137 ligand activated microglia induces oligodendrocyte apoptosis via reactive oxygen species. Journal of neuroinflammation. vol 9. 2013-06-10. PMID:22799524. |
in vitro co-culture confirmed that cd137l-activated microglia induces apoptosis in oligodendrocytes, and identified reactive oxygen species as the mechanism of apoptosis induction. |
2013-06-10 |
2023-08-12 |
mouse |
| Michael Fricker, Anna Vilalta, Aviva M Tolkovsky, Guy C Brow. Caspase inhibitors protect neurons by enabling selective necroptosis of inflamed microglia. The Journal of biological chemistry. vol 288. issue 13. 2013-05-30. PMID:23386613. |
we found that inflammatory stimuli (lps, lipoteichoic acid, or tnf-α) caused an increase in caspase-8 ietdase activity in primary rat microglia without inducing apoptosis. |
2013-05-30 |
2023-08-12 |
rat |
| Vikramjeet Singh, Elke Verena Voss, Karelle Bénardais, Martin Stange. Effects of 2-chlorodeoxyadenosine (Cladribine) on primary rat microglia. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 7. issue 4. 2013-05-24. PMID:22821377. |
treatment of microglia with cda inhibited their proliferation and induced apoptosis. |
2013-05-24 |
2023-08-12 |
rat |
| Vikramjeet Singh, Elke Verena Voss, Karelle Bénardais, Martin Stange. Effects of 2-chlorodeoxyadenosine (Cladribine) on primary rat microglia. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 7. issue 4. 2013-05-24. PMID:22821377. |
these data suggest a potential of cda treatment to induce not only leukopenia but also apoptosis in microglia in the cns. |
2013-05-24 |
2023-08-12 |
rat |
| Lihong Li, Jinqian Zhang, Yang Yang, Qiang Wang, Li Gao, Yanlong Yang, Tao Chang, Xingye Zhang, Guoan Xiang, Yongmei Cao, Zujin Shi, Ming Zhao, Guodong Ga. Single-wall carbon nanohorns inhibited activation of microglia induced by lipopolysaccharide through blocking of Sirt3. Nanoscale research letters. vol 8. issue 1. 2013-03-19. PMID:23432919. |
to address this question, the research about direct role of swnhs on the growth, proliferation, and apoptosis of microglia cell lines in mice (n9 and bv2) pre-treated with or without lps had been performed. |
2013-03-19 |
2023-08-12 |
mouse |
| Lihong Li, Jinqian Zhang, Yang Yang, Qiang Wang, Li Gao, Yanlong Yang, Tao Chang, Xingye Zhang, Guoan Xiang, Yongmei Cao, Zujin Shi, Ming Zhao, Guodong Ga. Single-wall carbon nanohorns inhibited activation of microglia induced by lipopolysaccharide through blocking of Sirt3. Nanoscale research letters. vol 8. issue 1. 2013-03-19. PMID:23432919. |
lps induced activation of mice microglia, promoted its growth and proliferation, and inhibited its apoptosis. |
2013-03-19 |
2023-08-12 |
mouse |
| Lihong Li, Jinqian Zhang, Yang Yang, Qiang Wang, Li Gao, Yanlong Yang, Tao Chang, Xingye Zhang, Guoan Xiang, Yongmei Cao, Zujin Shi, Ming Zhao, Guodong Ga. Single-wall carbon nanohorns inhibited activation of microglia induced by lipopolysaccharide through blocking of Sirt3. Nanoscale research letters. vol 8. issue 1. 2013-03-19. PMID:23432919. |
swnhs inhibited proliferation, delayed mitotic entry, and promoted apoptosis of mice microglia cells. |
2013-03-19 |
2023-08-12 |
mouse |
| Lihong Li, Jinqian Zhang, Yang Yang, Qiang Wang, Li Gao, Yanlong Yang, Tao Chang, Xingye Zhang, Guoan Xiang, Yongmei Cao, Zujin Shi, Ming Zhao, Guodong Ga. Single-wall carbon nanohorns inhibited activation of microglia induced by lipopolysaccharide through blocking of Sirt3. Nanoscale research letters. vol 8. issue 1. 2013-03-19. PMID:23432919. |
swnhs inhibited mitotic entry, growth and proliferation of mice microglia cells, and promoted its apoptosis, especially in cells pre-treated with lps. |
2013-03-19 |
2023-08-12 |
mouse |
| Xichao Wang, Qun Chen, Da Xin. Focal adhesion kinase activates NF-κB via the ERK1/2 and p38MAPK Pathways in amyloid-β25-35-induced apoptosis in PC12 cells. Journal of Alzheimer's disease : JAD. vol 32. issue 1. 2013-02-20. PMID:22776966. |
previous studies have demonstrated that in aβ-induced apoptosis of nerve cells, differentiated rat pheochromocytoma (pc12) cells, and microglia, nucleus factor kappa b (nf-κb) is activated. |
2013-02-20 |
2023-08-12 |
rat |
| Claudia A McCarthy, Antony Vinh, Brad R S Broughton, Christopher G Sobey, Jennifer K Callaway, Robert E Widdo. Angiotensin II type 2 receptor stimulation initiated after stroke causes neuroprotection in conscious rats. Hypertension (Dallas, Tex. : 1979). vol 60. issue 6. 2013-02-07. PMID:23090772. |
furthermore, we have demonstrated that at(2)r stimulation after stroke increased neuronal survival, decreased apoptosis, and caused an increase in the number of activated microglia in the core region of damage. |
2013-02-07 |
2023-08-12 |
rat |
| Congrong Guo, Atsushi Otani, Akio Oishi, Hiroshi Kojima, Yukiko Makiyama, Satoko Nakagawa, Nagahisa Yoshimur. Knockout of ccr2 alleviates photoreceptor cell death in a model of retinitis pigmentosa. Experimental eye research. vol 104. 2013-01-25. PMID:23022404. |
photoreceptor apoptosis (tunel staining) and the number of microglia (positive for the f4/80 antibody) in the retina were examined. |
2013-01-25 |
2023-08-12 |
mouse |