| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ke Yan, Run Zhang, Chengmei Sun, Lei Chen, Peng Li, Yi Liu, Lingmei Peng, Haitao Sun, Kun Qin, Fanfan Chen, Weiyi Huang, Yuxin Chen, Bingke Lv, Mouxuan Du, Yuxi Zou, Yingqian Cai, Lingsha Qin, Yanping Tang, Xiaodan Jian. Bone marrow-derived mesenchymal stem cells maintain the resting phenotype of microglia and inhibit microglial activation. PloS one. vol 8. issue 12. 2014-09-18. PMID:24391898. |
we found that bmsc-cm significantly induced apoptosis of microglia, while no apoptosis was apparent in the lps-stimulated microglia. |
2014-09-18 |
2023-08-12 |
Not clear |
| Zhengwei Li, Jincao Chen, Ting Lei, Huaqiu Zhan. Tamoxifen induces apoptosis of mouse microglia cell line BV-2 cells via both mitochondrial and death receptor pathways. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 32. issue 2. 2014-09-11. PMID:22528224. |
tamoxifen induces apoptosis of mouse microglia cell line bv-2 cells via both mitochondrial and death receptor pathways. |
2014-09-11 |
2023-08-12 |
mouse |
| Zhengwei Li, Jincao Chen, Ting Lei, Huaqiu Zhan. Tamoxifen induces apoptosis of mouse microglia cell line BV-2 cells via both mitochondrial and death receptor pathways. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 32. issue 2. 2014-09-11. PMID:22528224. |
little is known about whether tamoxifen (tam) can affect resting state microglia apoptosis and about the cellular mechanism that may account for this. |
2014-09-11 |
2023-08-12 |
mouse |
| Xiaochun Yang, Xuanchu Dua. Minocycline inhibits the production of the precursor form of nerve growth factor by retinal microglial cells. Neural regeneration research. vol 8. issue 4. 2014-09-10. PMID:25206672. |
these results suggested that minocycline inhibited the increased expression of the precursor form of nerve growth factor in microglia, the p75 neurotrophin receptor in astroglia, and protected cells from apoptosis. |
2014-09-10 |
2023-08-13 |
rat |
| Lining Ke, Wei Guo, Jianwen Xu, Guodong Zhang, Wei Wang, Wenhua Huan. Ginsenoside Rb1 attenuates activated microglia-induced neuronal damage. Neural regeneration research. vol 9. issue 3. 2014-09-10. PMID:25206809. |
ginsenoside rb1 protected neuronal morphology and structure in a single hypoxic culture system and in a hypoxic co-culture system with microglia, and reduced neuronal apoptosis and caspase-3 production. |
2014-09-10 |
2023-08-13 |
Not clear |
| Debora Cutuli, Paola De Bartolo, Paola Caporali, Daniela Laricchiuta, Francesca Foti, Maurizio Ronci, Claudia Rossi, Cristina Neri, Gianfranco Spalletta, Carlo Caltagirone, Stefano Farioli-Vecchioli, Laura Petrosin. n-3 polyunsaturated fatty acids supplementation enhances hippocampal functionality in aged mice. Frontiers in aging neuroscience. vol 6. 2014-09-09. PMID:25202271. |
in fact, n-3 pufa supplementation increased hippocampal neurogenesis and dendritic arborization of newborn neurons, volume, neuronal density and microglial cell number, while it decreased apoptosis, astrocytosis and lipofuscin accumulation in the hippocampus. |
2014-09-09 |
2023-08-13 |
mouse |
| H C Hoyos, M Rinaldi, S P Mendez-Huergo, M Marder, G A Rabinovich, J M Pasquini, L A Pasquin. Galectin-3 controls the response of microglial cells to limit cuprizone-induced demyelination. Neurobiology of disease. vol 62. 2014-09-03. PMID:24184798. |
cuprizone (cpz)-induced demyelination is characterized by the loss of mature oligodendrocytes (olg) by apoptosis, myelin sheath degeneration and recruitment of microglia and astrocytes to the lesioned area. |
2014-09-03 |
2023-08-12 |
mouse |
| Geetha Parthasarathy, Mario T Philip. The MEK/ERK pathway is the primary conduit for Borrelia burgdorferi-induced inflammation and P53-mediated apoptosis in oligodendrocytes. Apoptosis : an international journal on programmed cell death. vol 19. issue 1. 2014-09-02. PMID:24114360. |
in vitro analysis of this phenomenon indicated that while b. burgdorferi can induce inflammation and apoptosis of oligodendrocytes per se, microglia are required for neuronal apoptosis. |
2014-09-02 |
2023-08-12 |
human |
| Geetha Parthasarathy, Mario T Philip. The MEK/ERK pathway is the primary conduit for Borrelia burgdorferi-induced inflammation and P53-mediated apoptosis in oligodendrocytes. Apoptosis : an international journal on programmed cell death. vol 19. issue 1. 2014-09-02. PMID:24114360. |
we hypothesized that the inflammatory milieu elicited by the bacterium in microglia or oligodendrocytes contributes to the apoptosis of neurons and glial cells, respectively, and that downstream signaling events in nfkb and/or mapk pathways play a role in these phenotypes. |
2014-09-02 |
2023-08-12 |
human |
| N Xie, C Wang, Y Lian, C Wu, H Zhang, Q Zhan. Inhibition of mitochondrial fission attenuates Aβ-induced microglia apoptosis. Neuroscience. vol 256. 2014-08-27. PMID:24144623. |
inhibition of mitochondrial fission attenuates aβ-induced microglia apoptosis. |
2014-08-27 |
2023-08-12 |
Not clear |
| Shuxian Hu, Wen S Sheng, R Bryan Roc. CB2 receptor agonists protect human dopaminergic neurons against damage from HIV-1 gp120. PloS one. vol 8. issue 10. 2014-08-05. PMID:24147028. |
using a human mesencephalic neuronal/glial culture model, which contains dopaminergic neurons, microglia, and astrocytes, we were able to show that the cb1/cb2 agonist win55,212-2 blunts gp120-induced neuronal damage as measured by dopamine transporter function, apoptosis and lipid peroxidation; these actions were mediated principally by the cb2 receptor. |
2014-08-05 |
2023-08-12 |
human |
| Bo Peng, Jia Xiao, Ke Wang, Kwok-Fai So, George L Tipoe, Bin Li. Suppression of microglial activation is neuroprotective in a mouse model of human retinitis pigmentosa. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 24. 2014-08-04. PMID:24920619. |
inhibition of microglia activation by minocycline reduced photoreceptor apoptosis and significantly improved retinal structure and function and visual behavior in rd10 mice. |
2014-08-04 |
2023-08-13 |
mouse |
| Yoshihiro Seki, Takahiro A Kato, Akira Monji, Yoshito Mizoguchi, Hideki Horikawa, Mina Sato-Kasai, Daigo Yoshiga, Shigenobu Kanb. Pretreatment of aripiprazole and minocycline, but not haloperidol, suppresses oligodendrocyte damage from interferon-γ-stimulated microglia in co-culture model. Schizophrenia research. vol 151. issue 1-3. 2014-07-29. PMID:24100191. |
pretreatment of aripiprazole and minocycline suppressed apoptosis of oligodendrocytes in the co-culture model with interferon-γ (ifn-γ)-activated microglia, while haloperidol, a traditional antipsychotic drug, did not. |
2014-07-29 |
2023-08-12 |
Not clear |
| Yongzhi Fan, Jingli Chen, Jun Ye, Hong Yan, Yi Ca. Proteinase-activated receptor 2 modulates corticotropin releasing hormone-induced brain-derived neurotrophic factor release from microglial cells. Cell biology international. vol 38. issue 1. 2014-07-24. PMID:24174309. |
apoptosis was evident in microglia after activation by crh. |
2014-07-24 |
2023-08-12 |
Not clear |
| Yongzhi Fan, Jingli Chen, Jun Ye, Hong Yan, Yi Ca. Proteinase-activated receptor 2 modulates corticotropin releasing hormone-induced brain-derived neurotrophic factor release from microglial cells. Cell biology international. vol 38. issue 1. 2014-07-24. PMID:24174309. |
tryptase-induced par2 activation reduced the frequency of apoptosis of microglia, but enhanced the bdnf levels in the culture medium, which was partially blocked by par2 antagonists. |
2014-07-24 |
2023-08-12 |
Not clear |
| Xia Qin, Zhen-Quan Sun, Xue-Wei Zhang, Xiao-Jing Dai, Shan-Shan Mao, Yong-Mei Zhan. TLR4 signaling is involved in the protective effect of propofol in BV2 microglia against OGD/reoxygenation. Journal of physiology and biochemistry. vol 69. issue 4. 2014-07-17. PMID:23512249. |
bv2 microglia apoptosis was determined by flow cytometry. |
2014-07-17 |
2023-08-12 |
Not clear |
| Xia Qin, Zhen-Quan Sun, Xue-Wei Zhang, Xiao-Jing Dai, Shan-Shan Mao, Yong-Mei Zhan. TLR4 signaling is involved in the protective effect of propofol in BV2 microglia against OGD/reoxygenation. Journal of physiology and biochemistry. vol 69. issue 4. 2014-07-17. PMID:23512249. |
propofol pretreatment also significantly reduced the production of tnf-α and apoptosis in ogd/reoxygenation bv2 microglia. |
2014-07-17 |
2023-08-12 |
Not clear |
| Jingjing Zhuang, Haikun Zhang, Rong Zhou, Lili Chen, Jing Chen, Xu She. Regulation of prostaglandin F2α against β amyloid clearance and its inflammation induction through LXR/RXR heterodimer antagonism in microglia. Prostaglandins & other lipid mediators. vol 106. 2014-07-10. PMID:24076168. |
cell based assays indicated that pgf2α effectively antagonized the activation of lxr agonist (t0901317) on aβ clearance via inhibiting apolipoprotein e (apoe) expression, and cell apoptosis alleviation by accelerating inflammatory response to aβ or lipopolysaccharide (lps) in microglia. |
2014-07-10 |
2023-08-12 |
Not clear |
| Kun-Che Chang, Jessica Ponder, Daniel V Labarbera, J Mark Petras. Aldose reductase inhibition prevents endotoxin-induced inflammatory responses in retinal microglia. Investigative ophthalmology & visual science. vol 55. issue 5. 2014-06-23. PMID:24677107. |
retinal microglia become activated in diabetes and produce pro-inflammatory molecules associated with changes in retinal vasculature and increased apoptosis of retinal neurons and glial cells. |
2014-06-23 |
2023-08-12 |
Not clear |
| Yang Yu, Jin Liu, Shu-Qin Li, Lei Peng, Richard D Y. Serum amyloid a differentially activates microglia and astrocytes via the PI3K pathway. Journal of Alzheimer's disease : JAD. vol 38. issue 1. 2014-06-17. PMID:23948927. |
the viability of cultured primary microglia and astrocytes was measured by mtt; cell cycle and apoptosis analysis was also conducted. |
2014-06-17 |
2023-08-12 |
Not clear |