| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tim Clarner, Katharina Janssen, Lara Nellessen, Martin Stangel, Thomas Skripuletz, Barbara Krauspe, Franz-Martin Hess, Bernd Denecke, Clara Beutner, Bettina Linnartz-Gerlach, Harald Neumann, Luc Vallières, Sandra Amor, Kim Ohl, Klaus Tenbrock, Cordian Beyer, Markus Kip. CXCL10 triggers early microglial activation in the cuprizone model. Journal of immunology (Baltimore, Md. : 1950). vol 194. issue 7. 2015-06-08. PMID:25725102. |
in this study, we used the cuprizone model to investigate the temporal and causal relationship of oligodendrocyte apoptosis and early microglia activation. |
2015-06-08 |
2023-08-13 |
mouse |
| G Cantarella, G Pignataro, G Di Benedetto, S Anzilotti, A Vinciguerra, O Cuomo, G F Di Renzo, C Parenti, L Annunziato, R Bernardin. Ischemic tolerance modulates TRAIL expression and its receptors and generates a neuroprotected phenotype. Cell death & disease. vol 5. 2015-06-04. PMID:25032854. |
tnf-related apoptosis inducing ligand (trail), a member of the tnf superfamily released by microglia, appears to be involved in the induction of apoptosis following focal brain ischemia. |
2015-06-04 |
2023-08-13 |
rat |
| Lucy G Chastain, Dipak K Sarka. Role of microglia in regulation of ethanol neurotoxic action. International review of neurobiology. vol 118. 2015-05-12. PMID:25175862. |
particularly, microglia are implicated in alcohol-induced neuroinflammation and in alcohol-induced increases in oxidative stress, which can lead to neuronal apoptosis. |
2015-05-12 |
2023-08-13 |
Not clear |
| Candice Contet, Airee Kim, David Le, Siddharth K Iyengar, Roxanne W Kotzebue, Clara J Yuan, Brigitte L Kieffer, Chitra D Mandya. μ-Opioid receptors mediate the effects of chronic ethanol binge drinking on the hippocampal neurogenic niche. Addiction biology. vol 19. issue 5. 2015-05-11. PMID:23461397. |
mor deficiency did not alter progenitor proliferation, neuronal differentiation and maturation, apoptosis or microglia in ethanol-naïve mice. |
2015-05-11 |
2023-08-12 |
mouse |
| Yi-hua Zhang, He Chen, Ying Chen, Lu Wang, Yi-hong Cai, Min Li, Hui-qin Wen, Jian Du, Ran An, Qing-li Luo, Xue-long Wang, Zhao-Rong Lun, Yuan-hong Xu, Ji-long She. Activated microglia contribute to neuronal apoptosis in Toxoplasmic encephalitis. Parasites & vectors. vol 7. 2015-04-15. PMID:25128410. |
activated microglia contribute to neuronal apoptosis in toxoplasmic encephalitis. |
2015-04-15 |
2023-08-13 |
Not clear |
| Patricia Rivera, Laura Bindila, Antoni Pastor, Margarita Pérez-Martín, Francisco J Pavón, Antonia Serrano, Rafael de la Torre, Beat Lutz, Fernando Rodríguez de Fonseca, Juan Suáre. Pharmacological blockade of the fatty acid amide hydrolase (FAAH) alters neural proliferation, apoptosis and gliosis in the rat hippocampus, hypothalamus and striatum in a negative energy context. Frontiers in cellular neuroscience. vol 9. 2015-04-14. PMID:25870539. |
cell proliferation (phospho-h3(+) or brdu(+) cells) of the main adult neurogenic zones as well as apoptosis (cleaved caspase-3(+)), astroglia (gfap(+)), and microglia (iba1(+) cells) were analyzed in the hippocampus, hypothalamus and striatum of rats intraperitoneally treated with urb597 (0.3 mg/kg/day) at one dose/4-days resting or 5 doses (1 dose/day). |
2015-04-14 |
2023-08-13 |
rat |
| Miriam Hernangómez, Francisco J Carrillo-Salinas, Miriam Mecha, Fernando Correa, Leyre Mestre, Frida Loría, Ana Feliú, Fabian Docagne, Carmen Guaz. Brain innate immunity in the regulation of neuroinflammation: therapeutic strategies by modulating CD200-CD200R interaction involve the cannabinoid system. Current pharmaceutical design. vol 20. issue 29. 2015-04-13. PMID:24588829. |
in the absence of these regulators, when neurons die by apoptosis, become infected or damaged, microglia and infiltrating immune cells are free to cause injury as well as an adverse inflammatory response in acute and chronic settings. |
2015-04-13 |
2023-08-12 |
Not clear |
| Clara Quintas, Diana Pinho, Clara Pereira, Lucília Saraiva, Jorge Gonçalves, Glória Queiro. Microglia P2Y₆ receptors mediate nitric oxide release and astrocyte apoptosis. Journal of neuroinflammation. vol 11. 2015-03-30. PMID:25178395. |
microglia p2y₆ receptors mediate nitric oxide release and astrocyte apoptosis. |
2015-03-30 |
2023-08-13 |
Not clear |
| Maria Nikodemova, Rebecca S Kimyon, Ishani De, Alissa L Small, Lara S Collier, Jyoti J Watter. Microglial numbers attain adult levels after undergoing a rapid decrease in cell number in the third postnatal week. Journal of neuroimmunology. vol 278. 2015-03-23. PMID:25468773. |
during postnatal development, microglia, cns resident innate immune cells, are essential for synaptic pruning, neuronal apoptosis and remodeling. |
2015-03-23 |
2023-08-13 |
mouse |
| Jinbo Yin, Hong Li, Chenzhuo Feng, Zhiyi Zu. Inhibition of brain ischemia-caused notch activation in microglia may contribute to isoflurane postconditioning-induced neuroprotection in male rats. CNS & neurological disorders drug targets. vol 13. issue 4. 2015-02-23. PMID:24938773. |
our results suggest that notch activation in microglia contributes to the cell apoptosis in the ischemic brain tissues. |
2015-02-23 |
2023-08-13 |
rat |
| Wei Wang, Tao Wang, Wan-Yu Feng, Zhan-You Wang, Mao-Sheng Cheng, Yun-Jie Wan. Ecdysterone protects gerbil brain from temporal global cerebral ischemia/reperfusion injury via preventing neuron apoptosis and deactivating astrocytes and microglia cells. Neuroscience research. vol 81-82. 2015-02-21. PMID:24480536. |
ecdysterone protects gerbil brain from temporal global cerebral ischemia/reperfusion injury via preventing neuron apoptosis and deactivating astrocytes and microglia cells. |
2015-02-21 |
2023-08-12 |
Not clear |
| T Kreisel, M G Frank, T Licht, R Reshef, O Ben-Menachem-Zidon, M V Baratta, S F Maier, R Yirmiy. Dynamic microglial alterations underlie stress-induced depressive-like behavior and suppressed neurogenesis. Molecular psychiatry. vol 19. issue 6. 2015-01-09. PMID:24342992. |
we report that following an initial period (2-3 days) of stress-induced microglial proliferation and activation, some microglia underwent apoptosis, leading to reductions in their numbers within the hippocampus, but not in other brain regions, following 5 weeks of cus exposure. |
2015-01-09 |
2023-08-12 |
mouse |
| Qun Zhang, Lin Yuan, Dexiang Liu, Jianmei Wang, Shuanglian Wang, Qingrui Zhang, Yanfen Gong, Hongda Liu, Aijun Hao, Zhen Wan. Hydrogen sulfide attenuates hypoxia-induced neurotoxicity through inhibiting microglial activation. Pharmacological research. vol 84. 2015-01-05. PMID:24788079. |
in addition, treating murine primary cortical neurons with conditioned medium (cm) from hypoxia-stimulated microglia induced neuronal apoptosis, an effect that was reversed by cm treated with nahs. |
2015-01-05 |
2023-08-13 |
mouse |
| Takuji Ito, Kenji Yoshida, Takayuki Negishi, Masayasu Miyajima, Hyota Takamatsu, Hitoshi Kikutani, Atsushi Kumanogoh, Kazunori Yukaw. Plexin-A1 is required for Toll-like receptor-mediated microglial activation in the development of lipopolysaccharide-induced encephalopathy. International journal of molecular medicine. vol 33. issue 5. 2014-11-26. PMID:24604454. |
sema3a, secreted in higher amounts from injured neurons, is considered to suppress excessive inflammatory responses by inducing microglial apoptosis through its binding to plexin-a1 receptors on activated microglia. |
2014-11-26 |
2023-08-12 |
mouse |
| Lingfeng Wu, Kunnan Zhang, Guozhu Hu, Haiyu Yan, Chen Xie, Xiaomu W. Inflammatory response and neuronal necrosis in rats with cerebral ischemia. Neural regeneration research. vol 9. issue 19. 2014-11-25. PMID:25422636. |
in the ischemic zone, neurons undergo necrosis and apoptosis, and a large number of reactive microglia are present. |
2014-11-25 |
2023-08-13 |
rat |
| Xuqing Liu, Tak-Ho Chu, Huanxing Su, Anchen Guo, Wutian W. Neural progenitor cell apoptosis and differentiation were affected by activated microglia in spinal cord slice culture. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 35. issue 3. 2014-10-22. PMID:24052449. |
neural progenitor cell apoptosis and differentiation were affected by activated microglia in spinal cord slice culture. |
2014-10-22 |
2023-08-12 |
Not clear |
| Jee Youn Lee, Tae Young Yun. Ghrelin inhibits oligodendrocyte cell death by attenuating microglial activation. Endocrinology and metabolism (Seoul, Korea). vol 29. issue 3. 2014-10-13. PMID:25309797. |
therefore, in the present study, we examined whether ghrelin inhibits microglia activation and thereby inhibits oligodendrocyte apoptosis. |
2014-10-13 |
2023-08-13 |
Not clear |
| Mia Kim, Mal Soon Shin, Jae Min Lee, Han Sam Cho, Chang Ju Kim, Young Joon Kim, Hey Ran Choi, Jung Won Jeo. Inhibitory Effects of Isoquinoline Alkaloid Berberine on Ischemia-Induced Apoptosis via Activation of Phosphoinositide 3-Kinase/Protein Kinase B Signaling Pathway. International neurourology journal. vol 18. issue 3. 2014-10-03. PMID:25279238. |
a neuroprotective effect of berberine against cerebral ischemia has been reported; however, the effects of berberine on apoptosis in relation to reactive astrogliosis and microglia activation under ischemic conditions have not yet been fully evaluated. |
2014-10-03 |
2023-08-13 |
Not clear |
| Elisabet Frande-Cabanes, Lorena Fernandez-Prieto, Ricardo Calderon-Gonzalez, Estela Rodríguez-Del Río, Sonsoles Yañez-Diaz, Monica López-Fanarraga, Carmen Alvarez-Domíngue. Dissociation of innate immune responses in microglia infected with Listeria monocytogenes. Glia. vol 62. issue 2. 2014-09-26. PMID:24311463. |
these cytokines and toxic microglial products are also released by primary microglia, and this cytokine and chemokine cocktail display a low potential to trigger neuronal apoptosis. |
2014-09-26 |
2023-08-12 |
Not clear |
| Charanjit Kaur, Viswanathan Sivakumar, Zhirong Zou, Eng-Ang Lin. Microglia-derived proinflammatory cytokines tumor necrosis factor-alpha and interleukin-1beta induce Purkinje neuronal apoptosis via their receptors in hypoxic neonatal rat brain. Brain structure & function. vol 219. issue 1. 2014-09-19. PMID:23262920. |
moreover, cultured purkinje neurons treated with conditioned medium derived from hypoxic microglia underwent apoptosis but the incidence was significantly reduced when the cells were treated with the same medium that was neutralized with tnf-α/il-1β antibody. |
2014-09-19 |
2023-08-12 |
rat |