| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yong-Ping Zhang, Hao-Yin Wang, Cai Zhang, Bai-Ping Liu, Zhi-Lan Peng, Yu-Yu Li, Feng-Ming Liu, Cai Son. Mifepristone attenuates depression-like changes induced by chronic central administration of interleukin-1β in rats. Behavioural brain research. vol 347. 2018-11-13. PMID:29580890. |
sustained increase in gc may activate microglia to induce neuroinflammation, and suppress astrocytes to produce neurotrophins, which lead to neuronal apoptosis. |
2018-11-13 |
2023-08-13 |
rat |
| Miao Cai, Yan-Wen Wang, Shan-Hu Xu, Song Qiao, Qin-Fen Shu, Jian-Zong Du, Ya-Guo Li, Xiao-Li Li. Regulatory effects of the long non‑coding RNA RP11‑543N12.1 and microRNA‑324‑3p axis on the neuronal apoptosis induced by the inflammatory reactions of microglia. International journal of molecular medicine. vol 42. issue 3. 2018-10-29. PMID:29956723. |
regulatory effects of the long non‑coding rna rp11‑543n12.1 and microrna‑324‑3p axis on the neuronal apoptosis induced by the inflammatory reactions of microglia. |
2018-10-29 |
2023-08-13 |
Not clear |
| Ye Ji Jeong, Yeonghoon Son, Na-Kyung Han, Hyung-Do Choi, Jeong-Ki Pack, Nam Kim, Yun-Sil Lee, Hae-June Le. Impact of Long-Term RF-EMF on Oxidative Stress and Neuroinflammation in Aging Brains of C57BL/6 Mice. International journal of molecular sciences. vol 19. issue 7. 2018-10-29. PMID:30029554. |
in addition, levels of markers for dna damage (8-hydroxy-2'-deoxyguanosine, p53, p21, γh2ax, and bax), apoptosis (cleaved caspase-3 and cleaved poly(adp-ribose) polymerase 1 (parp-1)), astrocyte (gfap), and microglia (iba-1) were significantly elevated in the brains of aged mice. |
2018-10-29 |
2023-08-13 |
mouse |
| Ye Ji Jeong, Yeonghoon Son, Na-Kyung Han, Hyung-Do Choi, Jeong-Ki Pack, Nam Kim, Yun-Sil Lee, Hae-June Le. Impact of Long-Term RF-EMF on Oxidative Stress and Neuroinflammation in Aging Brains of C57BL/6 Mice. International journal of molecular sciences. vol 19. issue 7. 2018-10-29. PMID:30029554. |
however, long-term rf-emf exposure did not change the levels of oxidative stress, dna damage, apoptosis, astrocyte, or microglia markers in the aged mouse brains. |
2018-10-29 |
2023-08-13 |
mouse |
| Wenwen Dong, Bei Yang, Linlin Wang, Bingxuan Li, Xiangshen Guo, Miao Zhang, Zhenfei Jiang, Jingqi Fu, Jingbo Pi, Dawei Guan, Rui Zha. Curcumin plays neuroprotective roles against traumatic brain injury partly via Nrf2 signaling. Toxicology and applied pharmacology. vol 346. 2018-10-11. PMID:29571711. |
in wild type mice, curcumin treatment resulted in reduced ipsilateral cortex injury, neutrophil infiltration, and microglia activation, improving neuron survival against tbi-induced apoptosis and degeneration. |
2018-10-11 |
2023-08-13 |
mouse |
| Johanna Wiedemann, Khalid Rashid, Thomas Langman. Resveratrol induces dynamic changes to the microglia transcriptome, inhibiting inflammatory pathways and protecting against microglia-mediated photoreceptor apoptosis. Biochemical and biophysical research communications. vol 501. issue 1. 2018-10-09. PMID:29723528. |
resveratrol induces dynamic changes to the microglia transcriptome, inhibiting inflammatory pathways and protecting against microglia-mediated photoreceptor apoptosis. |
2018-10-09 |
2023-08-13 |
Not clear |
| Shuting Wu, Rongtao Xue, Shaoli Hassan, Thi My Linh Nguyen, Tienan Wang, Hongru Pan, Jin Xu, Qifa Liu, Wenqing Zhang, Zilong We. Il34-Csf1r Pathway Regulates the Migration and Colonization of Microglial Precursors. Developmental cell. vol 46. issue 5. 2018-09-28. PMID:30205037. |
we have recently demonstrated that neuronal apoptosis contributes to microglia colonization in zebrafish. |
2018-09-28 |
2023-08-13 |
zebrafish |
| Shuting Wu, Rongtao Xue, Shaoli Hassan, Thi My Linh Nguyen, Tienan Wang, Hongru Pan, Jin Xu, Qifa Liu, Wenqing Zhang, Zilong We. Il34-Csf1r Pathway Regulates the Migration and Colonization of Microglial Precursors. Developmental cell. vol 46. issue 5. 2018-09-28. PMID:30205037. |
our study shows that cytokine signaling and neuronal apoptosis synergistically orchestrate the colonization of microglia in early zebrafish development. |
2018-09-28 |
2023-08-13 |
zebrafish |
| Anssi Lipponen, Assam El-Osta, Antony Kaspi, Mark Ziemann, Ishant Khurana, Harikrishnan Kn, Vicente Navarro-Ferrandis, Noora Puhakka, Jussi Paananen, Asla Pitkäne. Transcription factors Tp73, Cebpd, Pax6, and Spi1 rather than DNA methylation regulate chronic transcriptomics changes after experimental traumatic brain injury. Acta neuropathologica communications. vol 6. issue 1. 2018-09-18. PMID:29482641. |
transcription regulatory network analysis revealed that these transcription factors regulate apoptosis, inflammation, and microglia, which are well-known contributors to secondary damage after tbi. library of integrated network-based cellular signatures (lincs) analysis identified 118 pharmacotherapies that regulate the expression of cebpd, pax6, spi1, and tp73. |
2018-09-18 |
2023-08-13 |
rat |
| Deqing Sun, Aiying Xue, Xia Xue, Manru Ren, Jing Wu, Rongmei Wan. Acetylpuerarin protects against OGD-induced cell injury in BV2 microglia by inhibiting HMGB1 release. Die Pharmazie. vol 73. issue 2. 2018-08-29. PMID:29442011. |
bv2 microglia viability after ogd with or without ap was measured by cck-8 assay, apoptosis of bv2 microglia was determined by hoechst 33258 staining and fitc-annexin v/7-aad staining. |
2018-08-29 |
2023-08-13 |
rat |
| Yu Zhang, Weida Gao, Kongbin Yang, Haiquan Tao, Haicheng Yan. Salt-Inducible Kinase 1 (SIK1) is Induced by Alcohol and Suppresses Microglia Inflammation via NF-κB Signaling. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 47. issue 4. 2018-08-15. PMID:29929190. |
microglia are a crucial part of alcohol-induced neuroinflammation and undergo apoptosis. |
2018-08-15 |
2023-08-13 |
Not clear |
| Yu Zhang, Weida Gao, Kongbin Yang, Haiquan Tao, Haicheng Yan. Salt-Inducible Kinase 1 (SIK1) is Induced by Alcohol and Suppresses Microglia Inflammation via NF-κB Signaling. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 47. issue 4. 2018-08-15. PMID:29929190. |
even though the importance of these inflammatory processes in the effects of alcohol-related neurodegeneration have been established, the mechanism of alcohol-induced microglia apoptosis is unknown. |
2018-08-15 |
2023-08-13 |
Not clear |
| Yu Zhang, Weida Gao, Kongbin Yang, Haiquan Tao, Haicheng Yan. Salt-Inducible Kinase 1 (SIK1) is Induced by Alcohol and Suppresses Microglia Inflammation via NF-κB Signaling. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 47. issue 4. 2018-08-15. PMID:29929190. |
in this study, we sought to determine what role sik1 expression plays in alcohol-induced neuroinflammation as well as whether and by what mechanism it regulates microglia apoptosis. |
2018-08-15 |
2023-08-13 |
Not clear |
| Lalita Subedi, Oh Wook Kwon, Chaeho Pak, Goeun Lee, Kangwoo Lee, Hakwon Kim, Sun Yeou Ki. N,N-disubstituted azines attenuate LPS-mediated neuroinflammation in microglia and neuronal apoptosis via inhibiting MAPK signaling pathways. BMC neuroscience. vol 18. issue 1. 2018-08-13. PMID:29281977. |
n,n-disubstituted azines attenuate lps-mediated neuroinflammation in microglia and neuronal apoptosis via inhibiting mapk signaling pathways. |
2018-08-13 |
2023-08-13 |
Not clear |
| Caixia Wang, Heyu Chen, Weihai Yin. Cytosolic aspartate aminotransferase mediates the mitochondrial membrane potential and cell survival by maintaining the calcium homeostasis of BV2 microglia. Neuroreport. vol 29. issue 2. 2018-08-06. PMID:29215467. |
our study found that decreased cast by cast sirna can lead to significant increases in the [ca]i, mitochondrial depolarization and apoptosis of bv2 microglia. |
2018-08-06 |
2023-08-13 |
Not clear |
| Christine Altmann, Mirko H H Schmid. The Role of Microglia in Diabetic Retinopathy: Inflammation, Microvasculature Defects and Neurodegeneration. International journal of molecular sciences. vol 19. issue 1. 2018-08-01. PMID:29301251. |
among other consequences, these changes in microglia severely affected retinal neurons, causing increased apoptosis and subsequent thinning of the nerve fiber layer, resulting in visual loss. |
2018-08-01 |
2023-08-13 |
Not clear |
| Xue Fang, Dingya Sun, Zhihong Wang, Zhongwang Yu, Weili Liu, Yingyan Pu, Dan Wang, Aijun Huang, Mingdong Liu, Zhenghua Xiang, Cheng He, Li Ca. MiR-30a Positively Regulates the Inflammatory Response of Microglia in Experimental Autoimmune Encephalomyelitis. Neuroscience bulletin. vol 33. issue 6. 2018-07-24. PMID:28717866. |
in vitro, the conditioned supernatant of mouse microglia overexpressing mir-30a promoted the apoptosis of oligodendrocyte precursor cells (opcs), and inhibited opc differentiation. |
2018-07-24 |
2023-08-13 |
mouse |
| Zhang Mengying, Xu Yiyue, Pan Tong, Hu Yue, Yanin Limpanont, Huang Ping, Kamolnetr Okanurak, Wu Yanqi, Paron Dekumyoy, Zhou Hongli, Dorn Watthanakulpanich, Wu Zhongdao, Wang Zhi, Lv Zhiyu. Apoptosis and necroptosis of mouse hippocampal and parenchymal astrocytes, microglia and neurons caused by Angiostrongylus cantonensis infection. Parasites & vectors. vol 10. issue 1. 2018-07-16. PMID:29258580. |
apoptosis and necroptosis of mouse hippocampal and parenchymal astrocytes, microglia and neurons caused by angiostrongylus cantonensis infection. |
2018-07-16 |
2023-08-13 |
mouse |
| Nanchang Xie, Chuanjie Wu, Cui Wang, Xuan Cheng, Lu Zhang, Haifeng Zhang, Yajun Lia. Inhibition of the mitochondrial calcium uniporter inhibits Aβ-induced apoptosis by reducing reactive oxygen species-mediated endoplasmic reticulum stress in cultured microglia. Brain research. vol 1676. 2018-06-12. PMID:28939404. |
inhibition of the mitochondrial calcium uniporter inhibits aβ-induced apoptosis by reducing reactive oxygen species-mediated endoplasmic reticulum stress in cultured microglia. |
2018-06-12 |
2023-08-13 |
Not clear |
| Jianping Wang, Xiaojie Fu, Di Zhang, Lie Yu, Zhengfang Lu, Yufeng Gao, Xianliang Liu, Jiang Man, Sijia Li, Nan Li, Menghan Wang, Xi Liu, Xuemei Chen, Weidong Zang, Qingwu Yang, Jian Wan. Effects of crenolanib, a nonselective inhibitor of PDGFR, in a mouse model of transient middle cerebral artery occlusion. Neuroscience. vol 364. 2018-06-08. PMID:28943249. |
downregulation of the pdgfr signaling pathway on days 7-9 with crenolanib significantly increased apoptosis of the neuroblasts that had migrated to the peri-infarct region, increased the number of activated microglia, and decreased the expression of brain-derived neurotrophic factor, neurotrophin-3, and interleukin-10. |
2018-06-08 |
2023-08-13 |
mouse |