| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaoyu Wang, Susan V McLennan, Terri J Allen, Tatiana Tsoutsman, Christopher Semsarian, Stephen M Twig. Adverse effects of high glucose and free fatty acid on cardiomyocytes are mediated by connective tissue growth factor. American journal of physiology. Cell physiology. vol 297. issue 6. 2009-12-29. PMID:19625611. |
in addition, these ctgf effects were through the tyrosine kinase a (trka) receptor with tyrosine kinase activity, which has previously been implicated in ctgf signaling: trka was phosphorylated by ctgf, and a specific trka blocker abrogated ctgf-induced effects on hypertrophy and apoptosis. |
2009-12-29 |
2023-08-12 |
mouse |
| Mikhail A Kolpakov, Rachid Seqqat, Khadija Rafiq, Hang Xi, Kennneth B Margulies, Joseph R Libonati, Pamela Powel, Steven R Houser, Louis J Dell'italia, Abdelkarim Sabr. Pleiotropic effects of neutrophils on myocyte apoptosis and left ventricular remodeling during early volume overload. Journal of molecular and cellular cardiology. vol 47. issue 5. 2009-12-24. PMID:19716828. |
neutrophil infiltration blockade attenuated mmp activation, ecm degradation, and myocyte apoptosis induced by acf at 24 hours and attenuated the development of eccentric hypertrophy induced by acf at 2 and 3 weeks, suggesting a causal relationship between neutrophils and the acf-induced cardiac remodeling. |
2009-12-24 |
2023-08-12 |
rat |
| Mikhail A Kolpakov, Rachid Seqqat, Khadija Rafiq, Hang Xi, Kennneth B Margulies, Joseph R Libonati, Pamela Powel, Steven R Houser, Louis J Dell'italia, Abdelkarim Sabr. Pleiotropic effects of neutrophils on myocyte apoptosis and left ventricular remodeling during early volume overload. Journal of molecular and cellular cardiology. vol 47. issue 5. 2009-12-24. PMID:19716828. |
these data support a functional role for neutrophils in mmp activation, ecm degradation, and myocyte apoptosis during eccentric cardiac hypertrophy and underscore the adverse effects of chronic anti-neutrophil therapy on cardiac remodeling induced by early volume overload. |
2009-12-24 |
2023-08-12 |
rat |
| Olebogeng H I Majane, Leanda Vengethasamy, Eugene F du Toit, Siyanda Makaula, Angela J Woodiwiss, Gavin R Norto. Dietary-induced obesity hastens the progression from concentric cardiac hypertrophy to pump dysfunction in spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979). vol 54. issue 6. 2009-12-17. PMID:19841294. |
this effect may be mediated through a proclivity of shrs to developing both obesity-induced effects on cardiomyocyte apoptosis and activation of myocardial collagenases through leptin resistance and obesity-induced hypertrophy. |
2009-12-17 |
2023-08-12 |
rat |
| Long-yun Peng, Hong M. [Role of glycogen synthase kinase-3beta in cardiac hypertrophy and cardiocyte apoptosis]. Zhonghua xin xue guan bing za zhi. vol 33. issue 8. 2009-12-15. PMID:16188080. |
[role of glycogen synthase kinase-3beta in cardiac hypertrophy and cardiocyte apoptosis]. |
2009-12-15 |
2023-08-12 |
Not clear |
| Marcin Bujak, Nikolaos G Frangogianni. The role of IL-1 in the pathogenesis of heart disease. Archivum immunologiae et therapiae experimentalis. vol 57. issue 3. 2009-12-09. PMID:19479203. |
il-1 signaling may also be an essential mediator in the pathogenesis of heart failure by suppressing cardiac contractility, promoting myocardial hypertrophy, and inducing cardiomyocyte apoptosis. |
2009-12-09 |
2023-08-12 |
human |
| Farida Djouad, Claire Bony, François Canovas, Olivia Fromigué, Thierry Rème, Christian Jorgensen, Danièle Noë. Transcriptomic analysis identifies Foxo3A as a novel transcription factor regulating mesenchymal stem cell chrondrogenic differentiation. Cloning and stem cells. vol 11. issue 3. 2009-12-08. PMID:19751111. |
therefore, our findings suggest that upregulation of foxo3a over the course of chondrogenic differentiation plays a dual role, mainly inhibiting the differentiation process toward hypertrophy and promoting cell apoptosis. |
2009-12-08 |
2023-08-12 |
human |
| Alena A Zalutskaya, Megan K Cox, Marie B Dema. Phosphate regulates embryonic endochondral bone development. Journal of cellular biochemistry. vol 108. issue 3. 2009-11-24. PMID:19681042. |
by 8 days in culture, an increase caspase-9 activation and apoptosis of hypertrophic chondrocytes was observed in the metatarsals cultured in 7 mm phosphate. |
2009-11-24 |
2023-08-12 |
mouse |
| Shoufeng Wang, Yong Qiu, Zezhang Zhu, Zhaolong Ma, Caiwei Xia, Feng Zh. Histomorphological study of the spinal growth plates from the convex side and the concave side in adolescent idiopathic scoliosis. Journal of orthopaedic surgery and research. vol 2. 2009-11-10. PMID:17996118. |
the proliferative potential indexes and apoptosis indexes of chondrocytes in the proliferative and hypertrophic zone in the convex side were significantly higher than that in the concave side in the apex vertebral growth plate (p < 0.05). |
2009-11-10 |
2023-08-12 |
Not clear |
| Erin Stitt-Cavanagh, Laura MacLeod, Chris Kenned. The podocyte in diabetic kidney disease. TheScientificWorldJournal. vol 9. 2009-11-04. PMID:19838599. |
injury to these epithelial cells, podocytopathies, includes cellular hypertrophy, foot process effacement, detachment from the glomerular basement membrane, and apoptosis. |
2009-11-04 |
2023-08-12 |
Not clear |
| Zhao He-nan, Wang Yan, Jiang Miao-na, Zhang Cai-hua, Li Shen, Jia Yu-ji. Relation of Cardiotrophin-1 (CT-1) and cardiac transcription factor GATA4 expression in rat's cardiac myocytes hypertrophy and apoptosis. Pathology, research and practice. vol 205. issue 9. 2009-10-27. PMID:19327894. |
relation of cardiotrophin-1 (ct-1) and cardiac transcription factor gata4 expression in rat's cardiac myocytes hypertrophy and apoptosis. |
2009-10-27 |
2023-08-12 |
rat |
| Andrea L Koekemoer, Nelson W Chong, Alison H Goodall, Nilesh J Saman. Myocyte stress 1 plays an important role in cellular hypertrophy and protection against apoptosis. FEBS letters. vol 583. issue 17. 2009-10-22. PMID:19686740. |
myocyte stress 1 plays an important role in cellular hypertrophy and protection against apoptosis. |
2009-10-22 |
2023-08-12 |
Not clear |
| Andrea L Koekemoer, Nelson W Chong, Alison H Goodall, Nilesh J Saman. Myocyte stress 1 plays an important role in cellular hypertrophy and protection against apoptosis. FEBS letters. vol 583. issue 17. 2009-10-22. PMID:19686740. |
the aim of this study was to determine whether ms1 induces cellular hypertrophy and protects against apoptosis. |
2009-10-22 |
2023-08-12 |
Not clear |
| Andrea L Koekemoer, Nelson W Chong, Alison H Goodall, Nilesh J Saman. Myocyte stress 1 plays an important role in cellular hypertrophy and protection against apoptosis. FEBS letters. vol 583. issue 17. 2009-10-22. PMID:19686740. |
these findings suggest the involvement of ms1 in cellular hypertrophy and protection against apoptosis. |
2009-10-22 |
2023-08-12 |
Not clear |
| Chun-Hsien Chu, Chih-Yang Huang, Ming-Chin Lu, James A Lin, Fuu-Jen Tsai, Chang-Hai Tsai, Chia-Yih Chu, Wu-Hsien Kuo, Li-Mien Chen, Ling-Yun Che. Enhancement of AG1024-induced H9c2 cardiomyoblast cell apoptosis via the interaction of IGF2R with Galpha proteins and its downstream PKA and PLC-beta modulators by IGF-II. The Chinese journal of physiology. vol 52. issue 1. 2009-10-16. PMID:19764351. |
our previous studies found that insulin-like growth factor-i receptor (igf1r) signaling blockade caused cardiac hypertrophy, and that apoptosis is required for upregulating the igf-ii and the igf-ii/ mannose 6-phosphate receptor (igf2r) gene. |
2009-10-16 |
2023-08-12 |
Not clear |
| Rodolfo Guardado-Mendoza, Alberto M Davalli, Alberto O Chavez, Gene B Hubbard, Edward J Dick, Abraham Majluf-Cruz, Carlos E Tene-Perez, Lukasz Goldschmidt, John Hart, Carla Perego, Anthony G Comuzzie, Maria Elizabeth Tejero, Giovanna Finzi, Claudia Placidi, Stefano La Rosa, Carlo Capella, Glenn Halff, Amalia Gastaldelli, Ralph A DeFronzo, Franco Foll. Pancreatic islet amyloidosis, beta-cell apoptosis, and alpha-cell proliferation are determinants of islet remodeling in type-2 diabetic baboons. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 33. 2009-10-08. PMID:19666551. |
these results strongly support the concept that ia and beta-cell apoptosis in concert with alpha-cell proliferation and hypertrophy are key determinants of islets of langerhans "dysfunctional remodeling" and hyperglycemia in the baboon, a nonhuman primate model of type-2 diabetes mellitus. |
2009-10-08 |
2023-08-12 |
Not clear |
| Stephen C Kolwicz, Scott M MacDonnell, Brian F Renna, Patricia O Reger, Rachid Seqqat, Khadija Rafiq, Zebulon V Kendrick, Steven R Houser, Abdelkarim Sabri, Joseph R Libonat. Left ventricular remodeling with exercise in hypertension. American journal of physiology. Heart and circulatory physiology. vol 297. issue 4. 2009-10-08. PMID:19666835. |
cardiomyocyte hypertrophy, apoptosis, and proliferation in hearts from female spontaneously hypertensive rats (shrs) were examined. |
2009-10-08 |
2023-08-12 |
rat |
| Kenichi Watanabe, R A Thandavarayan, N Gurusamy, S Zhang, A J Muslin, K Suzuki, H Tachikawa, M Kodama, Y Aizaw. Role of 14-3-3 protein and oxidative stress in diabetic cardiomyopathy. Acta physiologica Hungarica. vol 96. issue 3. 2009-10-06. PMID:19706371. |
myocardial apoptosis, hypertrophy and fibrosis are the most frequently proposed mechanisms to explain cardiac changes in diabetic cardiomyopathy. |
2009-10-06 |
2023-08-12 |
Not clear |
| Hiroyuki Tsutsui, Shintaro Kinugawa, Shouji Matsushim. Oxidative stress and mitochondrial DNA damage in heart failure. Circulation journal : official journal of the Japanese Circulation Society. vol 72 Suppl A. 2009-10-02. PMID:18772530. |
reactive oxygen species induce myocyte hypertrophy, apoptosis, and interstitial fibrosis by activating matrix metalloproteinases. |
2009-10-02 |
2023-08-12 |
Not clear |
| Heng Kong, Qingsheng Yu, Liu Zh. [Experimental study on artesunate inducing apoptosis of hypertrophic scar fibroblasts]. Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery. vol 21. issue 9. 2009-09-30. PMID:17933233. |
[experimental study on artesunate inducing apoptosis of hypertrophic scar fibroblasts]. |
2009-09-30 |
2023-08-12 |
Not clear |