| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Man Yu, Yonggang Liu, Fan Xiang, Yuxin Li, Darragh Cullen, Ronglih Liao, Richard P Beyer, Theodor K Bammler, Michael T Chi. CHF1/Hey2 promotes physiological hypertrophy in response to pressure overload through selective repression and activation of specific transcriptional pathways. Omics : a journal of integrative biology. vol 13. issue 6. 2010-03-01. PMID:20001863. |
these findings demonstrate that chf1/hey2 promotes physiological over pathological hypertrophy through suppression of apoptosis and regulation of multiple transcriptional pathways. |
2010-03-01 |
2023-08-12 |
mouse |
| Matthew D Christensen, Wen Dun, Penelope A Boyden, Mark E Anderson, Peter J Mohler, Thomas J Hun. Oxidized calmodulin kinase II regulates conduction following myocardial infarction: a computational analysis. PLoS computational biology. vol 5. issue 12. 2010-02-23. PMID:19997488. |
calmodulin kinase ii (camkii) mediates critical signaling pathways responsible for divergent functions in the heart including calcium cycling, hypertrophy and apoptosis. |
2010-02-23 |
2023-08-12 |
Not clear |
| Sangita Choudhury, Soochan Bae, Sheetal R Kumar, Qingen Ke, Bhargavi Yalamarti, Jun H Choi, Lorrie A Kirshenbaum, Peter M Kan. Role of AIF in cardiac apoptosis in hypertrophic cardiomyocytes from Dahl salt-sensitive rats. Cardiovascular research. vol 85. issue 1. 2010-02-19. PMID:19633014. |
role of aif in cardiac apoptosis in hypertrophic cardiomyocytes from dahl salt-sensitive rats. |
2010-02-19 |
2023-08-12 |
rat |
| Xiao-Mei Li, Yi-Tong Ma, Yi-Ning Yang, Fen Liu, Bang-Dang Chen, Wei Han, Jian-Fa Zhang, Xiao-Ming Ga. Downregulation of survival signalling pathways and increased apoptosis in the transition of pressure overload-induced cardiac hypertrophy to heart failure. Clinical and experimental pharmacology & physiology. vol 36. issue 11. 2010-02-18. PMID:19566828. |
downregulation of survival signalling pathways and increased apoptosis in the transition of pressure overload-induced cardiac hypertrophy to heart failure. |
2010-02-18 |
2023-08-12 |
mouse |
| Xiao-Mei Li, Yi-Tong Ma, Yi-Ning Yang, Fen Liu, Bang-Dang Chen, Wei Han, Jian-Fa Zhang, Xiao-Ming Ga. Downregulation of survival signalling pathways and increased apoptosis in the transition of pressure overload-induced cardiac hypertrophy to heart failure. Clinical and experimental pharmacology & physiology. vol 36. issue 11. 2010-02-18. PMID:19566828. |
transition from compensated left ventricular (lv) hypertrophy to decompensated heart failure was characterized using a pressure-overload induced model to elucidate the temporal relationship between cardiomyocyte apoptosis and survival signalling in this transition. |
2010-02-18 |
2023-08-12 |
mouse |
| Xiao-Mei Li, Yi-Tong Ma, Yi-Ning Yang, Fen Liu, Bang-Dang Chen, Wei Han, Jian-Fa Zhang, Xiao-Ming Ga. Downregulation of survival signalling pathways and increased apoptosis in the transition of pressure overload-induced cardiac hypertrophy to heart failure. Clinical and experimental pharmacology & physiology. vol 36. issue 11. 2010-02-18. PMID:19566828. |
downregulation of erk1/2, akt and gsk3beta and enhanced cardiomyocyte apoptosis are implicated as important mechanisms in the transition from compensated hypertrophy to heart failure. |
2010-02-18 |
2023-08-12 |
mouse |
| Feng-Guo Zhai, Xin-Hua Zhang, Huai-Liang Wan. Fluoxetine protects against monocrotaline-induced pulmonary arterial hypertension: potential roles of induction of apoptosis and upregulation of Kv1.5 channels in rats. Clinical and experimental pharmacology & physiology. vol 36. issue 8. 2010-02-05. PMID:19298536. |
suppressing apoptosis and downregulating k(+) channels in pulmonary artery smooth muscle cells (pasmc) have been implicated in the development of pulmonary vascular medial hypertrophy and pulmonary arterial hypertension (pah). |
2010-02-05 |
2023-08-12 |
rat |
| Ezequiel J Molina, Jon Palma, Dipin Gupta, John P Gaughan, Steven Houser, Mahender Mach. Right ventricular effects of intracoronary delivery of mesenchymal stem cells (MSC) in an animal model of pressure overload heart failure. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 63. issue 10. 2010-02-03. PMID:18993028. |
in a rat model of left ventricular pressure overload hypertrophy with biventricular failure, we studied the effects of intracoronary delivery of mesenchymal stem cells (mcs) upon right ventricular hemodynamic performance, profiles of local inflammation and apoptosis, and determinants of extracellular matrix remodeling. |
2010-02-03 |
2023-08-12 |
rat |
| Ezequiel J Molina, Jon Palma, Dipin Gupta, John P Gaughan, Steven Houser, Mahender Mach. Right ventricular effects of intracoronary delivery of mesenchymal stem cells (MSC) in an animal model of pressure overload heart failure. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 63. issue 10. 2010-02-03. PMID:18993028. |
in this model of left ventricular pressure overload hypertrophy and biventricular failure, intracoronary delivery of msc was associated with an improvement in the right ventricular hemodynamic performance, profiles of local inflammation and apoptosis, and determinants of extracellular matrix remodeling. |
2010-02-03 |
2023-08-12 |
rat |
| Paul E Rosenstiel, Justin Chan, Alexander Snyder, Vicente Planelles, Vivette D D'Agati, Paul E Klotman, Mary E Klotma. HIV-1 Vpr activates the DNA damage response in renal tubule epithelial cells. AIDS (London, England). vol 23. issue 15. 2010-02-01. PMID:19657269. |
recently, we have shown that hiv-1 vpr causes hypertrophy, hyperploidy, and apoptosis. |
2010-02-01 |
2023-08-12 |
mouse |
| Roberto Ferrari, Claudio Ceconi, Gianluca Campo, Elisa Cangiano, Caterina Cavazza, Paola Secchiero, Luigi Tavazz. Mechanisms of remodelling: a question of life (stem cell production) and death (myocyte apoptosis). Circulation journal : official journal of the Japanese Circulation Society. vol 73. issue 11. 2010-02-01. PMID:19822975. |
remodeling myocytes show a typical switch between the embryonic and classical features of apoptosis and/or hypertrophy representing a signal of death (ie, apoptosis) and a signal of life (ie, hypertrophy). |
2010-02-01 |
2023-08-12 |
Not clear |
| Roberto Ferrari, Claudio Ceconi, Gianluca Campo, Elisa Cangiano, Caterina Cavazza, Paola Secchiero, Luigi Tavazz. Mechanisms of remodelling: a question of life (stem cell production) and death (myocyte apoptosis). Circulation journal : official journal of the Japanese Circulation Society. vol 73. issue 11. 2010-02-01. PMID:19822975. |
the reinstatement of apoptosis and development of hypertrophy during remodeling could be part of the switch forward to the embryonic phenotype with reinstatement of the early embryonic genetic program. |
2010-02-01 |
2023-08-12 |
Not clear |
| Roberto Ferrari, Claudio Ceconi, Gianluca Campo, Elisa Cangiano, Caterina Cavazza, Paola Secchiero, Luigi Tavazz. Mechanisms of remodelling: a question of life (stem cell production) and death (myocyte apoptosis). Circulation journal : official journal of the Japanese Circulation Society. vol 73. issue 11. 2010-02-01. PMID:19822975. |
hypertrophy and apoptosis are "sons" of the same "mother": the local, tissue neuroendocrine-neurohumoral response to a mechanical stretch of the myocytes consequent to the geometric changes imposed on the viable myocytes by the necrotic ones. |
2010-02-01 |
2023-08-12 |
Not clear |
| Bao-Feng Yang, Yan-Jie Lu, Zhi-Guo Wan. MicroRNAs and apoptosis: implications in the molecular therapy of human disease. Clinical and experimental pharmacology & physiology. vol 36. issue 10. 2010-01-26. PMID:19566826. |
one of the most active fields of mirna research is mirna regulation of apoptosis, a programmed cell death implicated in many human diseases, such as cancer, alzheimer's disease, hypertrophy and heart failure. |
2010-01-26 |
2023-08-12 |
human |
| Alwin Scharstuhl, Henricus A M Mutsaers, Sebastiaan W C Pennings, Frans G M Russel, Frank A D T G Wagene. Involvement of VDAC, Bax and ceramides in the efflux of AIF from mitochondria during curcumin-induced apoptosis. PloS one. vol 4. issue 8. 2010-01-19. PMID:19693275. |
we previously identified curcumin as a potent inducer of fibroblast apoptosis, which could be used to treat hypertrophic scar formation. |
2010-01-19 |
2023-08-12 |
Not clear |
| Tomoatsu Kimur. [Progress of research in osteoarthritis. An overview of the recent knowledge on osteoarthritis: pathogenesis, evaluation and therapies]. Clinical calcium. vol 19. issue 11. 2010-01-19. PMID:19880987. |
recent investigations are further deepening the understanding on the importance of matrix-degrading enzymes, chondrocyte hypertrophy and apoptosis, subchondral bone metabolism, cytokines and inflammation. |
2010-01-19 |
2023-08-12 |
Not clear |
| Ashwin Akki, Min Zhang, Colin Murdoch, Alison Brewer, Ajay M Sha. NADPH oxidase signaling and cardiac myocyte function. Journal of molecular and cellular cardiology. vol 47. issue 1. 2010-01-06. PMID:19374908. |
of the five known nadph oxidase isoforms, several are expressed in cardiovascular cells where they are involved in physiological and pathological processes such as the regulation of vascular tone, cell growth, migration, proliferation, hypertrophy, apoptosis and matrix deposition. |
2010-01-06 |
2023-08-12 |
Not clear |
| Xiaoyu Wang, Susan V McLennan, Terri J Allen, Tatiana Tsoutsman, Christopher Semsarian, Stephen M Twig. Adverse effects of high glucose and free fatty acid on cardiomyocytes are mediated by connective tissue growth factor. American journal of physiology. Cell physiology. vol 297. issue 6. 2009-12-29. PMID:19625611. |
diabetic cardiomyopathy is characterized by interstitial fibrosis and cardiomyocyte hypertrophy and apoptosis. |
2009-12-29 |
2023-08-12 |
mouse |
| Xiaoyu Wang, Susan V McLennan, Terri J Allen, Tatiana Tsoutsman, Christopher Semsarian, Stephen M Twig. Adverse effects of high glucose and free fatty acid on cardiomyocytes are mediated by connective tissue growth factor. American journal of physiology. Cell physiology. vol 297. issue 6. 2009-12-29. PMID:19625611. |
hearts from streptozotocin-induced diabetic rats had elevated ctgf and changes of pathological myocardial hypertrophy, fibrosis, and cardiomyocyte apoptosis. |
2009-12-29 |
2023-08-12 |
mouse |
| Xiaoyu Wang, Susan V McLennan, Terri J Allen, Tatiana Tsoutsman, Christopher Semsarian, Stephen M Twig. Adverse effects of high glucose and free fatty acid on cardiomyocytes are mediated by connective tissue growth factor. American journal of physiology. Cell physiology. vol 297. issue 6. 2009-12-29. PMID:19625611. |
small interfering rna against ctgf blocked the high glucose and palmitate induction of hypertrophy and apoptosis. |
2009-12-29 |
2023-08-12 |
mouse |