| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pei-li Yang, Yu-huan Liu, Ying Cui, Zai-long Cai, Ji-fang Ma. [Adenoviral-mediated expression of PTEN cDNA induces apoptosis in endometrial carcinoma cells]. Zhonghua fu chan ke za zhi. vol 41. issue 8. 2008-02-14. PMID:17083842. |
[adenoviral-mediated expression of pten cdna induces apoptosis in endometrial carcinoma cells]. |
2008-02-14 |
2023-08-12 |
human |
| Pei-li Yang, Yu-huan Liu, Ying Cui, Zai-long Cai, Ji-fang Ma. [Adenoviral-mediated expression of PTEN cDNA induces apoptosis in endometrial carcinoma cells]. Zhonghua fu chan ke za zhi. vol 41. issue 8. 2008-02-14. PMID:17083842. |
to investigate whether the human endometrial carcinoma cells, rl95-2 infected with recombinant ad-pten can steadily produce pten protein and enter apoptosis. |
2008-02-14 |
2023-08-12 |
human |
| Huachuan Zheng, Hiroyuki Takahashi, Yoshihiro Murai, Zhengguo Cui, Kazuhiro Nomoto, Koichi Tsuneyama, Yasuo Takan. Low expression of FHIT and PTEN correlates with malignancy of gastric carcinomas: tissue-array findings. Applied immunohistochemistry & molecular morphology : AIMM. vol 15. issue 4. 2008-02-08. PMID:18091387. |
it was suggested that down-regulated expression of fhit and pten contributed to gastric carcinogenesis possibly by involving in the imbalance between apoptosis and proliferation of cells. |
2008-02-08 |
2023-08-12 |
human |
| Umit A Kayisli, Murat Berkkanoglu, Gulnur Kizilay, Levent Senturk, Aydin Aric. Expression of proliferative and preapoptotic molecules in human myometrium and leiomyoma throughout the menstrual cycle. Reproductive sciences (Thousand Oaks, Calif.). vol 14. issue 7. 2008-01-22. PMID:18000229. |
a higher fasl level in the leiomyoma is likely to correspond to suppression of local immunity by inducing apoptosis of immune cells, while a higher level of pcna and a lower level of pten may be related to increased mitogenesis and decreased apoptosis in leiomyoma. |
2008-01-22 |
2023-08-12 |
human |
| Michiel T van Diepen, Britta J Eickhol. Function of PTEN during the formation and maintenance of neuronal circuits in the brain. Developmental neuroscience. vol 30. issue 1-3. 2008-01-16. PMID:18075255. |
pten (phosphatase and tensin homologue deleted on chromosome 10) is a tumor suppressor that can inhibit proliferation and migration and controls apoptosis in a number of cell types, mainly through inhibition of the phosphoinositide 3-kinase (pi3k) signaling pathway. |
2008-01-16 |
2023-08-12 |
Not clear |
| Ran Zhang, Naren L Banik, Swapan K Ra. Combination of all-trans retinoic acid and interferon-gamma suppressed PI3K/Akt survival pathway in glioblastoma T98G cells whereas NF-kappaB survival signaling in glioblastoma U87MG cells for induction of apoptosis. Neurochemical research. vol 32. issue 12. 2008-01-02. PMID:17616812. |
glioblastoma cells without functional pten are not easily amenable to apoptosis. |
2008-01-02 |
2023-08-12 |
human |
| Xiangyong Li, Guanping Lin, Binhua Wu, Xin Zhou, Keyuan Zho. Overexpression of PTEN induces cell growth arrest and apoptosis in human breast cancer ZR-75-1 cells. Acta biochimica et biophysica Sinica. vol 39. issue 10. 2008-01-02. PMID:17928923. |
overexpression of pten induces cell growth arrest and apoptosis in human breast cancer zr-75-1 cells. |
2008-01-02 |
2023-08-12 |
human |
| Xiangyong Li, Guanping Lin, Binhua Wu, Xin Zhou, Keyuan Zho. Overexpression of PTEN induces cell growth arrest and apoptosis in human breast cancer ZR-75-1 cells. Acta biochimica et biophysica Sinica. vol 39. issue 10. 2008-01-02. PMID:17928923. |
phosphatase and tensin homolog (pten) is a tumor suppressor gene located at human chromosome 10q23, might play an important role in cell proliferation, cell cycle and apoptosis of cancer cells. |
2008-01-02 |
2023-08-12 |
human |
| Xiangyong Li, Guanping Lin, Binhua Wu, Xin Zhou, Keyuan Zho. Overexpression of PTEN induces cell growth arrest and apoptosis in human breast cancer ZR-75-1 cells. Acta biochimica et biophysica Sinica. vol 39. issue 10. 2008-01-02. PMID:17928923. |
this study shows that overexpression of pten in zr-75-1 cells leads to cell growth arrest and apoptosis. |
2008-01-02 |
2023-08-12 |
human |
| Jian-jun Li, Hong-yu Li, Yan-zhi Chen, Guang Li, Yan Xi. [Exogenous PTEN enhances apoptosis in pancreas cancer cell line ASPC-1 induced by hypoxia]. Zhonghua zhong liu za zhi [Chinese journal of oncology]. vol 28. issue 5. 2007-12-27. PMID:17044997. |
[exogenous pten enhances apoptosis in pancreas cancer cell line aspc-1 induced by hypoxia]. |
2007-12-27 |
2023-08-12 |
human |
| Georg Pfeiler, Felicitas Horn, Claus Lattrich, Stefanie Klappenberger, Olaf Ortmann, Oliver Treec. Apoptotic effects of signal transduction inhibitors on human tumor cells with different PTEN expression. Oncology reports. vol 18. issue 5. 2007-12-13. PMID:17914589. |
when cells were treated with mapk inhibitors, no correlation between pten expression and the apoptosis rate was observed. |
2007-12-13 |
2023-08-12 |
human |
| Georg Pfeiler, Felicitas Horn, Claus Lattrich, Stefanie Klappenberger, Olaf Ortmann, Oliver Treec. Apoptotic effects of signal transduction inhibitors on human tumor cells with different PTEN expression. Oncology reports. vol 18. issue 5. 2007-12-13. PMID:17914589. |
our data underline the importance of pten expression regarding the induction of apoptosis through various targeted therapies. |
2007-12-13 |
2023-08-12 |
human |
| X Wan, J Li, X Xie, W L. PTEN augments doxorubicin-induced apoptosis in PTEN-null Ishikawa cells. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society. vol 17. issue 4. 2007-11-29. PMID:17359293. |
pten augments doxorubicin-induced apoptosis in pten-null ishikawa cells. |
2007-11-29 |
2023-08-12 |
Not clear |
| X Wan, J Li, X Xie, W L. PTEN augments doxorubicin-induced apoptosis in PTEN-null Ishikawa cells. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society. vol 17. issue 4. 2007-11-29. PMID:17359293. |
to investigate whether pten can augment doxorubicin-induced apoptosis in pten-null ishikawa cells. |
2007-11-29 |
2023-08-12 |
Not clear |
| X Wan, J Li, X Xie, W L. PTEN augments doxorubicin-induced apoptosis in PTEN-null Ishikawa cells. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society. vol 17. issue 4. 2007-11-29. PMID:17359293. |
our present results indicate that pten transfection significantly enhances doxorubicin chemosensitivity through effective induction of apoptosis by downregulation of the pi3k/akt/pkb signaling pathway in ishikawa cells. |
2007-11-29 |
2023-08-12 |
Not clear |
| Krishna Murthi Vasudevan, Ravshan Burikhanov, Anindya Goswami, Vivek M Rangneka. Suppression of PTEN expression is essential for antiapoptosis and cellular transformation by oncogenic Ras. Cancer research. vol 67. issue 21. 2007-11-27. PMID:17974977. |
jun(+/+) cells undergo cellular transformation by oncogenic ras, and restoration of wild-type pten, but not a phosphate-defective mutant of pten, induces apoptosis in these cells. |
2007-11-27 |
2023-08-12 |
human |
| Krishna Murthi Vasudevan, Ravshan Burikhanov, Anindya Goswami, Vivek M Rangneka. Suppression of PTEN expression is essential for antiapoptosis and cellular transformation by oncogenic Ras. Cancer research. vol 67. issue 21. 2007-11-27. PMID:17974977. |
conversely, in jun(-/-) cells, oncogenic ras neither suppresses pten nor causes transformation, but rather it induces pten-dependent apoptosis. |
2007-11-27 |
2023-08-12 |
human |
| Xinmin Li, Hali Wang, Edward Touma, Yuchen Qi, Emma Rousseau, Richard J Quigg, James T Ryab. TP508 accelerates fracture repair by promoting cell growth over cell death. Biochemical and biophysical research communications. vol 364. issue 1. 2007-11-26. PMID:17942078. |
this appears to occur through the stimulation of several bone healing pathways including cell cycle-g1/s checkpoint regulation, apoptosis, jak/stat, nf-kappab, pdgf, pi3k/akt, pten, and erk/mapk. |
2007-11-26 |
2023-08-12 |
human |
| Ping Song, Yong Wu, Jian Xu, Zhonglin Xie, Yunzhou Dong, Miao Zhang, Ming-Hui Zo. Reactive nitrogen species induced by hyperglycemia suppresses Akt signaling and triggers apoptosis by upregulating phosphatase PTEN (phosphatase and tensin homologue deleted on chromosome 10) in an LKB1-dependent manner. Circulation. vol 116. issue 14. 2007-11-19. PMID:17875968. |
reactive nitrogen species induced by hyperglycemia suppresses akt signaling and triggers apoptosis by upregulating phosphatase pten (phosphatase and tensin homologue deleted on chromosome 10) in an lkb1-dependent manner. |
2007-11-19 |
2023-08-12 |
Not clear |
| Karuppaiyah Selvendiran, Liyue Tong, Shilpa Vishwanath, Anna Bratasz, Nancy J Trigg, Vijay K Kutala, Kalman Hideg, Periannan Kuppusam. EF24 induces G2/M arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by increasing PTEN expression. The Journal of biological chemistry. vol 282. issue 39. 2007-11-08. PMID:17684018. |
ef24 induces g2/m arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by increasing pten expression. |
2007-11-08 |
2023-08-12 |
human |