| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fulya Ustün Alkan, Oya Ustüner, Tülay Bakırel, Suzan Cınar, Gaye Erten, Günnur Deni. The effects of piroxicam and deracoxib on canine mammary tumour cell line. TheScientificWorldJournal. vol 2012. 2013-06-05. PMID:23251109. |
mtt assay was performed to determine cell viability, and flow cytometric analyses were performed to evaluate apoptosis and cell cycle alterations. |
2013-06-05 |
2023-08-12 |
Not clear |
| Rongyuan Qiu, Songbai Wang, Xihua Feng, Feng Chen, Kaikai Yang, Shengsong H. Effect of subcellular localization of P21 on proliferation and apoptosis of HepG2 cells. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 31. issue 6. 2013-06-03. PMID:22173494. |
the cell proliferation was measured by mtt, and the cell cycle and apoptosis of hepg2 cells by flow cytometry. |
2013-06-03 |
2023-08-12 |
human |
| Zhiqing Liu, Liang Zhu, Hua Qin, Demin Li, Zuoqi Xie, Xiaoyu Ke, Qiu Zha. Re-expression of cell adhesion molecule inhibits growth and induces apoptosis of human pancreatic cancer cell line PANC-1. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 31. issue 6. 2013-06-03. PMID:22173495. |
cell growth was measured by the mtt method and cell apoptosis by flow cytometry. |
2013-06-03 |
2023-08-12 |
human |
| Yan Zhang, Xihong Xing, Hongfeng Zhan, Qiaoyu Li, Yu Fan, Liping Zhan, Qiang Yu, Jian Che. EGFR inhibitor enhances cisplatin sensitivity of human glioma cells. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 31. issue 6. 2013-06-03. PMID:22173497. |
cell growth, cell cycle distribution and cell apoptosis were determined by mtt method and flow cytometry, respectively. |
2013-06-03 |
2023-08-12 |
human |
| Thasni K A, Ratheeshkumar T, Rojini G, Sivakumar K C, Rakesh Sathish Nair, Srinivas G, Asoke Banerji, Veena Somasundaram, Priya Sriniva. Structure activity relationship of plumbagin in BRCA1 related cancer cells. Molecular carcinogenesis. vol 52. issue 5. 2013-06-03. PMID:22290577. |
methods like mtt assay, apoptosis analysis by flow cytometry, assessment of mitochondrial membrane potential-Δψm , suppression subtractive hybridization, microarray, molecular docking and estrogen receptor-dna binding activity by electrophoresis mobility shift assay (emsa) were adopted for assessing the anticancer activity. |
2013-06-03 |
2023-08-12 |
Not clear |
| Priscila de Matos Cândido-Bacani, Mateus Prates Mori, Tamara Regina Calvo, Wagner Vilegas, Eliana Aparecida Varanda, Ilce Mara de Syllos Cólu. In vitro assessment of the cytotoxic, apoptotic, and mutagenic potentials of isatin. Journal of toxicology and environmental health. Part A. vol 76. issue 6. 2013-05-28. PMID:23557234. |
the aim of the present study was to determine in vitro the cytotoxic, mutagenic, and apoptotic effects of isatin on cho-k1 and hela cells using the mtt viability assay (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide), micronucleus (mn) test, apoptosis index, and nuclear division index (ndi). |
2013-05-28 |
2023-08-12 |
human |
| Priscila de Matos Cândido-Bacani, Mateus Prates Mori, Tamara Regina Calvo, Wagner Vilegas, Eliana Aparecida Varanda, Ilce Mara de Syllos Cólu. In vitro assessment of the cytotoxic, apoptotic, and mutagenic potentials of isatin. Journal of toxicology and environmental health. Part A. vol 76. issue 6. 2013-05-28. PMID:23557234. |
the 5 isatin concentrations evaluated in the mutagenicity and apoptosis tests were 0.5, 1, 5, 10, and 50 μm, selected through a preliminary mtt assay. |
2013-05-28 |
2023-08-12 |
human |
| Ling-Fei Wu, Bi-Liu Wei, Yi-Tian Guo, Yan-Qing Ye, Guo-Ping Li, Ze-Jin Pu, Jia-Lin Fen. Apoptosis induced by adenosine involves endoplasmic reticulum stress in EC109 cells. International journal of molecular medicine. vol 30. issue 4. 2013-05-24. PMID:22859272. |
the mtt assay was used to determine cell proliferation; cell cycle detection (fcm) and terminal deoxynucleotidyl transferase-mediated dutp nick end labeling (tunel) assay were performed to determine cell apoptosis. |
2013-05-24 |
2023-08-12 |
Not clear |
| Hye Young Park, Gi-Young Kim, Taeg Kyu Kwon, Hye Jin Hwang, Nam Deuk Kim, Young Hyun Yoo, Yung Hyun Cho. Apoptosis induction of human leukemia U937 cells by 7,8-dihydroxyflavone hydrate through modulation of the Bcl-2 family of proteins and the MAPKs signaling pathway. Mutation research. vol 751. issue 2. 2013-05-23. PMID:23262352. |
7,8-dhf treatment of u937 cells resulted in inhibition of growth and induction of apoptosis as measured by mtt assay, fluorescence microscopy, dna fragmentation, and flow cytometry analysis. |
2013-05-23 |
2023-08-12 |
human |
| Na Yuan, Yan-Hong Wang, Ke-Jin Li, Yue Zhao, Xin Hu, Li Mao, Wen-Jie Zhao, Hong-Zhen Lian, Wei-Juan Zhen. Effects of exogenous zinc on the cellular zinc distribution and cell cycle of A549 cells. Bioscience, biotechnology, and biochemistry. vol 76. issue 11. 2013-05-17. PMID:23132559. |
in addition, an mtt assay and flow cytometric analysis showed that the znso(4) treatment led to a bi-phasic variation in viability and a slight fluctuation in the apoptosis of a549 cells. |
2013-05-17 |
2023-08-12 |
human |
| Hai-Bo Liu, Mei Zhang, Cheng-Liang Li, Peng-Cheng H. [Effect of clofarabine on proliferation and Bcl-2 expression of NB4 cells]. Zhongguo shi yan xue ye xue za zhi. vol 20. issue 3. 2013-05-16. PMID:22739157. |
mtt method was used to detect proliferation of nb4 cells treated with clofarabine 0.01 - 0.1 µmol/l for 48 h. the treated with clofarabine 0.01 - 0.1 µmol/l for 24 h, apoptosis rate and bcl-2 expression of nb4 cells were measured by flow cytometry and western blot respectively. |
2013-05-16 |
2023-08-12 |
Not clear |
| Xiao-Xia Wang, Xiao-Qin Liu, Wei Zhang, Xuan Chen, Li Zha. [Orphanin FQ combined with adriamycin reverses multi-drug resistance of K562/ADM and its molecular mechanism]. Zhongguo shi yan xue ye xue za zhi. vol 20. issue 3. 2013-05-16. PMID:22739158. |
mtt method was used to detect the proliferation ability of k562/adm treated with ofq and adm alone and their combination; flow cytometry was performed to measure the cell apoptosis rate; real time-pcr was applied to detect the mdr1 mran expression; western blot was used to determine the p-gp expression. |
2013-05-16 |
2023-08-12 |
Not clear |
| Rita Negrão, João Incio, Rui Lopes, Isabel Azevedo, Raquel Soare. Evidence for the Effects of Xanthohumol in Disrupting Angiogenic, but not Stable Vessels. International journal of biomedical science : IJBS. vol 3. issue 4. 2013-05-16. PMID:23675054. |
treatment with 10 μm xn significantly decreased viability and invasion capacity and increased apoptosis in both cell types as assessed by mtt, double-chamber assay and tunel assay respectively. |
2013-05-16 |
2023-08-12 |
human |
| Wei Tan, Wei Zhou, Hong-gang Yu, He-Sheng Luo, Lei She. The DNA methyltransferase inhibitor zebularine induces mitochondria-mediated apoptosis in gastric cancer cells in vitro and in vivo. Biochemical and biophysical research communications. vol 430. issue 1. 2013-05-14. PMID:23167995. |
in the study, the effects of zebularine on the growth and apoptosis of gastric cancer cells were investigated by mtt assay, hoechst assay, western blot analysis, flow cytometric analysis of annexin v-fitc/pi staining, and tunel assay. |
2013-05-14 |
2023-08-12 |
mouse |
| Takhellambam S Devi, Ken-Ichi Hosoya, Tetsuya Terasaki, Lalit P Sing. Critical role of TXNIP in oxidative stress, DNA damage and retinal pericyte apoptosis under high glucose: implications for diabetic retinopathy. Experimental cell research. vol 319. issue 7. 2013-05-14. PMID:23353834. |
furthermore, pericyte apoptosis is demonstrated by dna fragmentation (alkaline comet assay) and a reduction in mtt survival assay. |
2013-05-14 |
2023-08-12 |
rat |
| Yi Huang, Jian-Da Hu, Yuan-Lin Qi, Yan-An Wu, Jing Zheng, Ying-Yu Chen, Xiao-Li Huan. [Effect of knocking down eEF1A1 gene on proliferation and apoptosis in Jurkat cells and its mechanisms]. Zhongguo shi yan xue ye xue za zhi. vol 20. issue 4. 2013-05-09. PMID:22931638. |
cell proliferation, apoptosis and cycle were detected by mtt method, annexin v-apc labeling and dna ploidy analysis, respectively. |
2013-05-09 |
2023-08-12 |
human |
| Song-Mei Wang, Hong-Ying Wu, Jun-Qian Huang, Lu-Mei Hao, Li-Yan Wei, Xue-Mei L. [Effects of hyperbaric oxygenation combined with As(2)O(3) on proliferation of K562 cells and associated mechanism]. Zhongguo shi yan xue ye xue za zhi. vol 20. issue 4. 2013-05-09. PMID:22931643. |
the effects of drugs on proliferation of k562 cells was assayed by mtt method, the apoptosis rate of k562 cells was detected by flow cytometry with annexin v/pi double staining, the expressions of hif-1a, vegf, caspase-3 mrna of k562 cells were determined by real-time quantitative pcr. |
2013-05-09 |
2023-08-12 |
Not clear |
| Cheng Chen, Ji-Shi Wang, Chang Ynag, Yan-Yan Yu, Yan Li, Dan Ma, Qin Fan. [CML cell apoptosis induced by AMN107 combined with heme oxygenase-1 inhibitor]. Zhongguo shi yan xue ye xue za zhi. vol 20. issue 4. 2013-05-09. PMID:22931644. |
proliferative rate of cells treated with amn107 (10 µmol/l) and znppix (10 µmol/l) alone or both for different time was observed by mtt and trypan blue methods; the expression of ho-1 in the control group, znppix (10 µmol/l) group, amn107 (10 µmol/l) group, amn107 (10 µmol/l) combined with znppix (10 µmol/l) group was evaluated by semi-quantitative rt-pcr and western blot at 48 h. cell apoptosis was detected by flow cytometry with annexin v/pi double staining at 48 h. the results showed that the strongest inhibition of cell proliferation was detected in combined group, and in a time-dependent manner; the expression level of ho-1 was lowest in combined group; the cell apoptosis rates were (11.38 ± 0.02)%, (17.44 ± 0.08)%, (39.81 ± 0.07)% and (56.46 ± 0.19)% in the control group, znppix group, amn107 group, amn107 combined with znppix group at 48 h respectively. |
2013-05-09 |
2023-08-12 |
Not clear |
| Shi Jin, Yang Zhang, Qiang Wang, Dan Zhang, Song Zhan. Influence of TiN coating on the biocompatibility of medical NiTi alloy. Colloids and surfaces. B, Biointerfaces. vol 101. 2013-05-09. PMID:23010039. |
based on the orthodontic clinical application, the surface properties and biocompatibility were characterized by scanning electron microscopy (sem), x-ray diffraction (xrd), wettability test, mechanical test and in vitro tests including mtt, cell apoptosis and cell adhesion tests. |
2013-05-09 |
2023-08-12 |
Not clear |
| Shi Jin, Yang Zhang, Qiang Wang, Dan Zhang, Song Zhan. Influence of TiN coating on the biocompatibility of medical NiTi alloy. Colloids and surfaces. B, Biointerfaces. vol 101. 2013-05-09. PMID:23010039. |
mtt test showed no significant difference between the coated and uncoated niti-sma, however the percentage of early cell apoptosis was significantly higher as for the uncoated niti alloy. |
2013-05-09 |
2023-08-12 |
Not clear |