| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhu Li, Fang Fang, Feng X. Effects of different states of oxidative stress on fetal rat alveolar type II epithelial cells in vitro and ROS‑induced changes in Wnt signaling pathway expression. Molecular medicine reports. vol 7. issue 5. 2013-11-05. PMID:23525349. |
cell morphological changes were observed using an inverted microscope, the cell survival rate was determined by the mtt assay, and the apoptosis rate was determined using flow cytometry. |
2013-11-05 |
2023-08-12 |
rat |
| Francesco Mingoia, Caterina Di Sano, Francesco Di Blasi, Marco Fazzari, Annamaria Martorana, Anna Maria Almerico, Antonino Lauri. Exploring the anticancer potential of pyrazolo[1,2-a]benzo[1,2,3,4]tetrazin-3-one derivatives: the effect on apoptosis induction, cell cycle and proliferation. European journal of medicinal chemistry. vol 64. 2013-11-05. PMID:23644217. |
moreover, the apoptosis induction, based on mitochondrial membrane depolarization, was found in the range ec50 3-5 μm on hela cell, evidencing a well defined relationship with the related in vitro cell growth inhibitory assays (mtt) performed against other selected tumor cell lines not included in the nci tumor panel (hela, cervix; h292, lung; lan-5, cns; caco-2, colon; 16hbe, normal human cell lung) and against mcf-7 tumor cell line (breast). |
2013-11-05 |
2023-08-12 |
human |
| Li Jiang, Ruo-Yu Luo, Jing Yang, Yan-Xiang Chen. Knockdown of survivin contributes to antitumor activity in cisplatin-resistant ovarian cancer cells. Molecular medicine reports. vol 7. issue 2. 2013-11-04. PMID:23229441. |
proliferation was measured by mtt assay, invasive potential by transwell, and cell apoptosis by fitc-annexin v and propidium iodide for the functional analysis of a2780/cp cells following infection with ad5-svv. |
2013-11-04 |
2023-08-12 |
human |
| Xiao-Bao Yao, Xiao-Xia Wang, Hui Liu, Shao-Qiang Zhang, Hong-Liang Zh. Silencing Bmi-1 expression by RNA interference suppresses the growth of laryngeal carcinoma cells. International journal of molecular medicine. vol 31. issue 5. 2013-10-29. PMID:23525303. |
we used flow cytometry and tunel assay to analyze the apoptosis of transfected cells, and examined cellular growth in vitro by mtt assay. |
2013-10-29 |
2023-08-12 |
mouse |
| Aiping Wang, Baochao Zhang, Jiandang Zhang, Wei Wu, Wei W. Embelin-induced brain glioma cell apoptosis and cell cycle arrest via the mitochondrial pathway. Oncology reports. vol 29. issue 6. 2013-10-29. PMID:23545899. |
the mtt method was used to determine cell proliferation, and flow cytometry was used to determine apoptosis, as well as changes in the cell cycle and cell mitochondrial membrane potential. |
2013-10-29 |
2023-08-12 |
Not clear |
| Xiao-Dong Sun, Xing-E Liu, Dong-Sheng Huan. Curcumin reverses the epithelial-mesenchymal transition of pancreatic cancer cells by inhibiting the Hedgehog signaling pathway. Oncology reports. vol 29. issue 6. 2013-10-29. PMID:23563640. |
the growth inhibition rate of the cells was measured by mtt assay, apoptosis was detected by flow cytometry, the expression levels of shh, gli1, e-cadherin and vimentin were detected by western blot analysis, and cell invasion and migration ability were examined by transwell cell invasion assay and wound healing assay. |
2013-10-29 |
2023-08-12 |
Not clear |
| Guofu Chen, Haihe Wang, Shuli Xie, Jian Ma, Guangyi Wan. STAT1 negatively regulates hepatocellular carcinoma cell proliferation. Oncology reports. vol 29. issue 6. 2013-10-29. PMID:23588992. |
the effect of stat1 overexpression or silencing on the proliferation and apoptosis of hcc cells was determined by mtt and flow cytometric assays. |
2013-10-29 |
2023-08-12 |
human |
| Jeong-Woong Park, Stefan W Ryter, Sun Young Kyung, Sang Pyo Lee, Sung Hwan Jeon. The phosphodiesterase 4 inhibitor rolipram protects against cigarette smoke extract-induced apoptosis in human lung fibroblasts. European journal of pharmacology. vol 706. issue 1-3. 2013-10-28. PMID:23499692. |
cell viability and apoptosis were determined by mtt assay and annexin-v staining, respectively. |
2013-10-28 |
2023-08-12 |
mouse |
| F J Rodríguez-Lozano, I Serrano-Belmonte, J C Pérez Calvo, M T Coronado-Parra, A Bernabeu-Esclapez, J M Moraled. Effects of two low-shrinkage composites on dental stem cells (viability, cell damaged or apoptosis and mesenchymal markers expression). Journal of materials science. Materials in medicine. vol 24. issue 4. 2013-10-24. PMID:23354738. |
specimens from two low-shrinkage composites were eluted with culture medium for 24 h. after 24 h of incubation, cytotoxicity of elutes were evaluated by mtt assay; apoptosis was determined using the dna-specific fluorochrome hoechst 33342 and the mesenchymal stem cells markers expression was analyzed by immunofluorescence staining. |
2013-10-24 |
2023-08-12 |
Not clear |
| An-Ming Tang, Wei-Juan Wang, Bin Mei, Wang-Lai Hu, Mian Wu, Gao-Lin Lian. DEVD-based hydrogelator minimizes cellular apoptosis induction. Scientific reports. vol 3. 2013-10-24. PMID:23673405. |
3-(4,5-dimethylthiazol-2-yl) 2,5 diphenyl tetrazolium bromide (mtt) and western blot analyses indicated that dedv-based hydrogelator 2 induces cell death via apoptotic pathway while the devd-based hydrogelator 1 minimizes cellular apoptosis induction. |
2013-10-24 |
2023-08-12 |
Not clear |
| Morteza Eskandani, Hamed Hamishehkar, Jafar Ezzati Nazhad Dolatabad. Cyto/Genotoxicity study of polyoxyethylene (20) sorbitan monolaurate (tween 20). DNA and cell biology. vol 32. issue 9. 2013-10-24. PMID:23844597. |
at 40%-50% confluency, a549 cells and human umbilical vein endothelial cells were exposed to tween 20 at a recommended concentration for 24 h. after 24 h, to detect apoptosis and dna damage, the treated cells were subjected to 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay, fluorescein isothiocyanate (fitc)-labeled annexin v flow cytometry, dapi staining, comet, and dna ladder assays. |
2013-10-24 |
2023-08-12 |
human |
| Banalata Sahoo, K Sanjana P Devi, Rakesh Banerjee, Tapas K Maiti, Panchanan Pramanik, Dibakar Dhar. Thermal and pH responsive polymer-tethered multifunctional magnetic nanoparticles for targeted delivery of anticancer drug. ACS applied materials & interfaces. vol 5. issue 9. 2013-10-21. PMID:23551195. |
the biological activity of the dox-loaded mnps was studied by mtt assay, fluorescence microscopy, and apoptosis. |
2013-10-21 |
2023-08-12 |
Not clear |
| Ying-Bin Wang, Yi Hu, Zhen Li, Ping Wang, Yi-Xue Xue, Yi-Long Yao, Bo Yu, Yun-Hui Li. Artemether combined with shRNA interference of vascular cell adhesion molecule-1 significantly inhibited the malignant biological behavior of human glioma cells. PloS one. vol 8. issue 4. 2013-10-17. PMID:23593320. |
cell viability, migration, invasiveness and apoptosis were assessed with mtt, wound healing, transwell and annexin v-fitc/pi staining. |
2013-10-17 |
2023-08-12 |
human |
| Shi Liu, Xiao-Jie Wang, Ying Liu, Yun-Fu Cu. PI3K/AKT/mTOR signaling is involved in (-)-epigallocatechin-3-gallate-induced apoptosis of human pancreatic carcinoma cells. The American journal of Chinese medicine. vol 41. issue 3. 2013-10-17. PMID:23711146. |
in this study, the proliferation and apoptosis of panc-1 cells were examined by mtt assay and flow cytometry, respectively. |
2013-10-17 |
2023-08-12 |
human |
| H Sadeghi-Aliabadi, M Aliasgharluo, A Fattahi, M Mirian, M Ghannadia. In vitro cytotoxic evaluation of some synthesized COX-2 inhibitor derivatives against a panel of human cancer cell lines. Research in pharmaceutical sciences. vol 8. issue 4. 2013-10-01. PMID:24082899. |
the cytotoxic effects of four synthesisized analogues of celecoxib (coded as d, e, f and g) were evaluated against hela, mda-mb-231, a-2780-s and ht-29 cancer cells, using mtt assay; also their induction of apoptosis using dna fragmentation analysis were studied. |
2013-10-01 |
2023-08-12 |
human |
| Yan Song, Xin Sun, Wei-Liang Bai, Wen-Yue J. Antitumor effects of Dasatinib on laryngeal squamous cell carcinoma in vivo and in vitro. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. vol 270. issue 4. 2013-09-30. PMID:23404469. |
cell proliferation, cell cycle distribution, and cell apoptosis were evaluated using mtt assay, flow cytometry, and fluorescent microscopy. |
2013-09-30 |
2023-08-12 |
mouse |
| Xiuwei Wu, Anla Hu, Mingjun Zhang, Zhendong Che. Effects of Rab27a on proliferation, invasion, and anti-apoptosis in human glioma cell. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 34. issue 4. 2013-09-26. PMID:23553027. |
cell viability, cell cycle, cell apoptosis, and cell migration were analyzed, respectively, by (3-(4,5)-dimethylthi-azol-2-yl)-2,5-diphenytetrazolium bromide (mtt) assay, flow cytometry, and transwell invasion chamber methods. |
2013-09-26 |
2023-08-12 |
human |
| Ying Liu, Zu-an Zhu, Shang-Nuan Zhang, Jie Mou, Lei Liu, Tao Cui, Dong-Sheng Pe. Combinational effect of PPARγ agonist and RXR agonist on the growth of SGC7901 gastric carcinoma cells in vitro. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 34. issue 4. 2013-09-26. PMID:23605322. |
then, the cell growth, apoptosis, morphological changes, and the expression of pparγ, rxrγ, bcl-2, and bax were detected by mtt assay, flow cytometry, he staining, immunocytochemistry staining, and western blot assay, respectively. |
2013-09-26 |
2023-08-12 |
Not clear |
| X Z Cai, W Y Huang, Y Qiao, S Y Du, Y Chen, D Chen, S Yu, R C Che, N Liu, Y Jian. Inhibitory effects of curcumin on gastric cancer cells: a proteomic study of molecular targets. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 20. issue 6. 2013-09-23. PMID:23351961. |
3-(4,5-dimethyl-thiazol-2-yl)-2-5-diphenyltetrazolium-bromide (mtt) assay showed that curcumin inhibited cell growth in a dose- (1, 5, 10 and 30 μm) and time- (24, 48, 72 and 96 h) dependent manner; analysis of annexin v binding showed that curcumin induced apoptosis at the dose of 10 and 30 μm when the cells were treated for 24 and 48 h. as cancers are caused by dysregulation of various proteins, we investigated target proteins associated with curcumin by two-dimensional gel electrophoresis (2-de) and maldi-tof-tof mass spectrometer. |
2013-09-23 |
2023-08-12 |
Not clear |
| Jian-Xia Ma, Yun-Liang Sun, Yi-Qian Wang, Hong-Yu Wu, Jing Jin, Xiao-Feng Y. Triptolide induces apoptosis and inhibits the growth and angiogenesis of human pancreatic cancer cells by downregulating COX-2 and VEGF. Oncology research. vol 20. issue 8. 2013-09-23. PMID:23924856. |
cell viability and apoptosis were measured by mtt assay and flow cytometry. |
2013-09-23 |
2023-08-12 |
mouse |