| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jin Rhyu, Min Sook Kim, Mi-Kyoung You, Mi-Ae Bang, Hyeon-A Ki. Pear pomace water extract inhibits adipogenesis and induces apoptosis in 3T3-L1 adipocytes. Nutrition research and practice. vol 8. issue 1. 2014-03-10. PMID:24611103. |
the effects of pear pomace extract on cell viability and the anti-adipogenic and proapoptotic effects were investigated via mtt assay, oil red o staining, western blot analysis and apoptosis assay. |
2014-03-10 |
2023-08-12 |
Not clear |
| W Yang, X Wang, C Duan, L Lu, H Yan. Alpha-synuclein overexpression increases phospho-protein phosphatase 2A levels via formation of calmodulin/Src complex. Neurochemistry international. vol 63. issue 3. 2014-03-07. PMID:23796501. |
a tunel apoptosis assay and an mtt cell viability assay demonstrated that the pp2a activator c2-ceramide protected neurons against α-syn-induced cell injury. |
2014-03-07 |
2023-08-12 |
mouse |
| J Tian, Y X Duan, C Y Bei, J Che. Calycosin induces apoptosis by upregulation of RASD1 in human breast cancer cells MCF-7. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 45. issue 8. 2014-03-03. PMID:23609007. |
mcf-7 cells were treated with different concentrations of calycosin, and then detected by mtt assay for cellular viability, hoechst assay, and flow cytometry for apoptosis. |
2014-03-03 |
2023-08-12 |
human |
| Qiaoyin Zhang, Nianyu Huang, Junzhi Wang, Huajun Luo, Haibo He, Mingruo Ding, Wei-Qiao Deng, Kun Zo. The H+/K+-ATPase inhibitory activities of Trametenolic acid B from Trametes lactinea (Berk.) Pat, and its effects on gastric cancer cells. Fitoterapia. vol 89. 2014-02-27. PMID:23742858. |
in vitro, the anti-proliferation effect of tab to gastric cancer cell (hgc-27) in acid environment was detected by mtt, and the apoptosis morphological changes were also observed by hoechst 33258 dye assay. |
2014-02-27 |
2023-08-12 |
mouse |
| Xia Xie, Bo Tang, Jianyun Zhou, Qing Gao, Pengbing Zhan. Inhibition of the PI3K/Akt pathway increases the chemosensitivity of gastric cancer to vincristine. Oncology reports. vol 30. issue 2. 2014-02-27. PMID:23743572. |
the effect of ly294002 on cell viability, apoptosis induction and inhibition of tumor growth was analyzed using mtt and tunel assay in in vitro and in vivo models of gastric cancer. |
2014-02-27 |
2023-08-12 |
human |
| Ying Xiong, Wen Guo, Ting Li, Ke L. Influence of survivin-targeted siRNA on the biological features of colorectal carcinoma cells. Frontiers of medicine in China. vol 1. issue 3. 2014-02-27. PMID:24573871. |
apoptosis was detected by flow cytometry and cell proliferation was evaluated by mtt assay. |
2014-02-27 |
2023-08-12 |
Not clear |
| Ruyong Yao, Aihua Sui, Zhenli Wang, Shihai Liu, Quan Zhou, Xiangping Liu, Haiping Zhan. Induction of non-small cell lung carcinoma apoptosis using soluble RGD-TRAIL by targeting the integrin receptor of tumor cells. Molecular medicine reports. vol 6. issue 6. 2014-02-26. PMID:22965279. |
the antitumor effect of the purified rgd-trail on cell proliferation was evaluated in vitro using mtt and wound healing assays and cell apoptosis was assessed by hoechst 33342 staining and parp expression analysis. |
2014-02-26 |
2023-08-12 |
Not clear |
| Hong Li, Yaqiong Wang, Rongjuan X. Pingmu decoction enhances apoptosis of orbital adipocytes derived from patients with Graves' ophthalmophathy. Molecular medicine reports. vol 6. issue 6. 2014-02-26. PMID:22972028. |
our data demonstrate for the first time that pingmu decoction-containing serum significantly reduces preadipocyte proliferation and increases adipocyte apoptosis as measured by mtt assay and annexin v/fitc staining, respectively. |
2014-02-26 |
2023-08-12 |
Not clear |
| Xiao-Dong Sun, Xing-E Liu, Dong-Sheng Huan. Curcumin induces apoptosis of triple-negative breast cancer cells by inhibition of EGFR expression. Molecular medicine reports. vol 6. issue 6. 2014-02-26. PMID:23023821. |
the mda-mb-231 tnbc cells were treated with curcumin, the growth inhibition ratio of the cells was measured by mtt assay, apoptosis was detected by flow cytometry and the expression levels of extracellular regulated protein kinase (erk1/2), perk1/2, egfr and pegfr were detected by western blotting. |
2014-02-26 |
2023-08-12 |
Not clear |
| Ning Wang, Yibin Feng, Meifen Zhu, Fung-Ming Siu, Kwan-Ming Ng, Chi-Ming Ch. A novel mechanism of XIAP degradation induced by timosaponin AIII in hepatocellular carcinoma. Biochimica et biophysica acta. vol 1833. issue 12. 2014-02-24. PMID:23906794. |
cell viability was determined by mtt and cologenic assay; apoptosis was determined by flow cytometry and tunel assay; autophagy was examined by immunoblotting and immunofluorescence; ubiquitination was detected by co-immunoprecipitation; mrna expression was detected by real-time pcr; and determination of necrotic cell death was approached with ldh assay. |
2014-02-24 |
2023-08-12 |
human |
| Haijun Sun, Xianzhi Meng, Jihua Han, Zhe Zhang, Bing Wang, Xuedong Bai, Xin Zhan. Anti-cancer activity of DHA on gastric cancer--an in vitro and in vivo study. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 34. issue 6. 2014-02-21. PMID:23907579. |
a series of in vitro experiments including mtt, colony-forming, wound healing, invasion, cell cycle, cellular senescence, and apoptosis assays were performed to examine the antiproliferative and antimetastatic effects of dha on three gastric cancer cell lines, sgc-7901, bgc823, and mgc803. |
2014-02-21 |
2023-08-12 |
human |
| Yu Zhang, Chunsheng Xiao, Mingqiang Li, Jie Chen, Jianxun Ding, Chaoliang He, Xiuli Zhuang, Xuesi Che. Co-delivery of 10-hydroxycamptothecin with doxorubicin conjugated prodrugs for enhanced anticancer efficacy. Macromolecular bioscience. vol 13. issue 5. 2014-02-20. PMID:23420692. |
in vitro methyl thiazolyl tetrazolium (mtt) assays and drug-induced apoptosis tests demonstrate the hcpt-loaded nanoparticles suppress cancer cell growth more efficiently than the mpeg-b-pamam-dox prodrugs, free hcpt, and physical mixtures of mpeg-b-pamam-dox and hcpt at equivalent dox or hcpt doses. |
2014-02-20 |
2023-08-12 |
Not clear |
| Kuheli Das, Amitabha Datta, Chittaranjan Sinha, Jui-Hsien Huang, Eugenio Garribba, Ching-Sheng Hsiao, Chin-Lin Hs. End-to-End Thiocyanato-Bridged Helical Chain Polymer and Dichlorido-Bridged Copper(II) Complexes with a Hydrazone Ligand: Synthesis, Characterisation by Electron Paramagnetic Resonance and Variable-Temperature Magnetic Studies, and Inhibitory Effects on Human Colorectal Carcinoma Cells. ChemistryOpen. vol 1. issue 2. 2014-02-19. PMID:24551495. |
the biological effects of 1 and 2 on the viability of human colorectal carcinoma cells (colo-205 and ht-29) were evaluated using an mtt assay, and the results indicate that these complexes induce a decrease in cell-population growth of human colorectal carcinoma cells with apoptosis. |
2014-02-19 |
2023-08-12 |
human |
| Dong Xu, Qingguang Wang, Yong An, Lijian X. MiR‑203 regulates the proliferation, apoptosis and cell cycle progression of pancreatic cancer cells by targeting Survivin. Molecular medicine reports. vol 8. issue 2. 2014-02-13. PMID:23732815. |
proliferation, apoptosis and cell cycle profiles were detected by an mtt assay and flow cytometry. |
2014-02-13 |
2023-08-12 |
mouse |
| Fu-Ling Yan, Guo-Ling Han, Guan-Jin W. Cytotoxic role of advanced glycation end-products in PC12 cells treated with β‑amyloid peptide. Molecular medicine reports. vol 8. issue 2. 2014-02-13. PMID:23799541. |
apoptosis was measured by flow cytometry (fcm) and cell viability was measured by mtt assay. |
2014-02-13 |
2023-08-12 |
Not clear |
| Hong Lin, Huiling Zhang, Jun Wang, Meiping Lu, Feng Zheng, Changjun Wang, Xiaojun Tang, Ning Xu, Renjie Chen, Dawei Zhang, Ping Zhao, Jin Zhu, Yuan Mao, Zhenqing Fen. A novel human Fab antibody for Trop2 inhibits breast cancer growth in vitro and in vivo. International journal of cancer. vol 134. issue 5. 2014-02-12. PMID:23982827. |
mtt, apoptosis assay and wound healing assay were employed to evaluate the inhibitory effects of trop2 fab on breast cancer cell growth in vitro, while tumor-xenograft model was employed to evaluate the inhibitory effects on breast cancer growth in vivo. |
2014-02-12 |
2023-08-12 |
human |
| S Zhang, Y Qi, H Zhang, W He, Q Zhou, S Gui, Y Wan. Melatonin inhibits cell growth and migration, but promotes apoptosis in gastric cancer cell line, SGC7901. Biotechnic & histochemistry : official publication of the Biological Stain Commission. vol 88. issue 6. 2014-02-10. PMID:23477595. |
we investigated the effects of melatonin on cell proliferation, apoptosis, colony formation and cell migration in the gastric adenocarcinoma cell line, sgc7901, using mtt assay, hoechst 33258 staining, flow cytometry, western blot, caspase-3 activity assay, soft agar colony formation assay, and scratch-wound assay. |
2014-02-10 |
2023-08-12 |
Not clear |
| Ling-Xing Li, Xian-Feng Zhang, Xue Bai, Qian Ton. SDF-1 promotes ox-LDL induced vascular smooth muscle cell proliferation. Cell biology international. vol 37. issue 9. 2014-02-06. PMID:23658061. |
cell proliferation was measured with 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay, and apoptosis by flow cytometry. |
2014-02-06 |
2023-08-12 |
rat |
| Jian-Li Hu, Lan Xiao, Zhen-Yun Li, Qiong Wang, Yu Chang, Yi Ji. Upregulation of HO-1 is accompanied by activation of p38MAPK and mTOR in human oesophageal squamous carcinoma cells. Cell biology international. vol 37. issue 6. 2014-02-05. PMID:23412940. |
mtt assays were used to measure proliferation, facs for cell cycle events and annexin v staining for apoptosis. |
2014-02-05 |
2023-08-12 |
human |
| Ali Shao, Gang Chen, Nan Jiang, Ye Li, Xiao Zhang, Lu Wen, Fan Yang, Shaoyang We. Development and evaluation of self-microemulsifying liquid and granule formulations of Brucea javanica oil. Archives of pharmacal research. vol 36. issue 8. 2014-02-04. PMID:23595551. |
a methyl thiazolyl tetrazolium (mtt) assay was performed to identify cell apoptosis. |
2014-02-04 |
2023-08-12 |
Not clear |