| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rong Sun, Ke Wang, Dongdong Wu, Xiaoyu Li, Yangbing O. Protective effect of paeoniflorin against glutamate-induced neurotoxicity in PC12 cells via Bcl-2/Bax signal pathway. Folia neuropathologica. vol 50. issue 3. 2014-04-14. PMID:23023341. |
pc12 cells were cultured in vitro, cell viability was assessed by mtt assay, cell apoptosis as well as mitochondrial membrane potential (mmp) were detected by flow cytometric analysis and the expression profiles of apoptosis-related proteins including bcl-2 and bax were investigated by western blot. |
2014-04-14 |
2023-08-12 |
rat |
| Yan-Ming Lu, Meng-Li Rong, Chao Shang, Ning Wang, Xiang Li, Yan-Yan Zhao, Shu-Lan Zhan. Suppression of HER-2 via siRNA interference promotes apoptosis and decreases metastatic potential of SKOV‑3 human ovarian carcinoma cells. Oncology reports. vol 29. issue 3. 2014-04-11. PMID:23292493. |
skov-3 cells were examined for growth inhibition using the mtt proliferation assay and apoptosis was assessed using flow cytometry and tunel assay. |
2014-04-11 |
2023-08-12 |
human |
| Wei Song, Hai-Bo Yang, Pu Chen, Shu-Min Wang, Li-Pei Zhao, Wen-Hao Xu, Hai-Fang Fan, Xu Gu, Lan-Ying Che. Apoptosis of human gastric carcinoma SGC-7901 induced by deoxycholic acid via the mitochondrial-dependent pathway. Applied biochemistry and biotechnology. vol 171. issue 4. 2014-04-11. PMID:23943012. |
in the present study, effects of dca on sgc-7901 cell growth, cell cycle, and apoptosis were investigated by mtt assay, inverted microscopy, fluorescence microscopy, pi single- and fitc/pi double-staining flow cytometry, and western blotting. |
2014-04-11 |
2023-08-12 |
human |
| Baijun Li, Hui Lin, Jian Fan, Jiao Lan, Yonglong Zhong, Yong Yang, Hui Li, Zhiwei Wan. CD59 is overexpressed in human lung cancer and regulates apoptosis of human lung cancer cells. International journal of oncology. vol 43. issue 3. 2014-04-07. PMID:23835643. |
the proliferation and apoptosis of nci-h157 cells was measured by using mtt assay and facs. |
2014-04-07 |
2023-08-12 |
mouse |
| Qifeng Luo, Xiaoyu Li, Jia Li, Xiangjie Kong, Junfeng Zhang, Lei Chen, Yixiang Huang, Lin Fan. MiR-15a is underexpressed and inhibits the cell cycle by targeting CCNE1 in breast cancer. International journal of oncology. vol 43. issue 4. 2014-04-07. PMID:23900351. |
mtt assays, colony formation assays, transwell chamber migration assays, cell cycle and apoptosis assays were used to explore the potential function of mir-15a in mda-mb-231 human breast cancer cells. |
2014-04-07 |
2023-08-12 |
human |
| Prateek Jain, Nitesh Kumar, Venkata Rao Josyula, Hitesh Vitthal Jagani, N Udupa, C Mallikarjuna Rao, Palanimuthu Vasanth Ra. A study on the role of (+)-catechin in suppression of HepG2 proliferation via caspase dependent pathway and enhancement of its in vitro and in vivo cytotoxic potential through liposomal formulation. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. vol 50. issue 3-4. 2014-04-07. PMID:23954456. |
thus, this study was designed to explore cytotoxicity by mtt assay, induction of apoptosis via dna fragmentation, nuclear staining, bivariate flow cytometric analysis using annexin v- fitc and propidium iodide, cell cycle analysis and apoptotic markers by rt-pcr and western blotting in hepg2 cells. |
2014-04-07 |
2023-08-12 |
mouse |
| Ryu Yoshida, Mingyu Cheng, Martha M Murra. Increasing platelet concentration in platelet-rich plasma inhibits anterior cruciate ligament cell function in three-dimensional culture. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 32. issue 2. 2014-04-07. PMID:24122902. |
cellular metabolism (mtt assay), apoptosis (tunel assay), and gene expression for type i and type iii collagen were measured. |
2014-04-07 |
2023-08-12 |
Not clear |
| Tao Guo, Jia-Ming Qian, Yu-Qing Zhao, Xiao-Bo Li, Jian-Zhong Zhan. Effects of IL-1β on the proliferation and apoptosis of gastric epithelial cells and acid secretion from isolated rabbit parietal cells. Molecular medicine reports. vol 7. issue 1. 2014-04-01. PMID:23128938. |
mtt assay and flow cytometry (fcm) were used to determine the levels of proliferation and apoptosis. |
2014-04-01 |
2023-08-12 |
human |
| Hyun Soo Park, Hye Jin Hwang, Gi-Young Kim, Hee-Jae Cha, Wun-Jae Kim, Nam Deuk Kim, Young Hyun Yoo, Yung Hyun Cho. Induction of apoptosis by fucoidan in human leukemia U937 cells through activation of p38 MAPK and modulation of Bcl-2 family. Marine drugs. vol 11. issue 7. 2014-04-01. PMID:23880928. |
fucoidan treatment of cells resulted in inhibition of growth and induction of apoptosis, as measured by 3-(4,5-dimetylthiazol-2-yl)-2,5-diphenyl-tetrazolium (mtt) assay, fluorescence microscopy, dna fragmentation, and flow cytometry analysis. |
2014-04-01 |
2023-08-12 |
human |
| Jieqing Ma, Rongfa Guan, Haitao Shen, Fei Lu, Chaogeng Xiao, Mingqi Liu, Tianshu Kan. Comparison of anticancer activity between lactoferrin nanoliposome and lactoferrin in Caco-2 cells in vitro. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 59. 2014-03-28. PMID:23743119. |
the anticancer activities of lactoferrin (lf) and lf nanoliposomes in caco-2 cells were observed in this study, and mitochondrial function (mtt assay), count kit-8(cck-8), detection of intracellular reactive oxygen species (ros) and apoptosis induction (ao/eb staining) assays were used to evaluate the anticancer activity. |
2014-03-28 |
2023-08-12 |
human |
| Wengang Yang, Hui Zheng, Yongyi Wang, Feng Lian, Zhenglei Hu, Song Xu. Nesprin-1 plays an important role in the proliferation and apoptosis of mesenchymal stem cells. International journal of molecular medicine. vol 32. issue 4. 2014-03-27. PMID:23863972. |
cell proliferation was assessed by mtt assay, and the cell cycle and apoptosis were detected by flow cytometry. |
2014-03-27 |
2023-08-12 |
rat |
| Aruljothi Subramaniam, Ser Yue Loo, Peramaiyan Rajendran, Kanjoormana A Manu, Ekambaram Perumal, Feng Li, Muthu K Shanmugam, Kodappully Sivaraman Siveen, Joo-In Park, Kwang Seok Ahn, Kam M Hui, Alan P Kumar, Gautam Seth. An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell survival proteins. Apoptosis : an international journal on programmed cell death. vol 18. issue 10. 2014-03-26. PMID:23700228. |
as observed by mtt cytotoxicity assay and the externalization of the membrane phospholipid phosphatidylserine, we found that emodin can significantly potentiate trail-induced apoptosis in hcc cells. |
2014-03-26 |
2023-08-12 |
Not clear |
| Rui Zhang, Min Li, Wenqiao Zang, Xudong Chen, Yuanyuan Wang, Ping Li, Yuwen Du, Guoqiang Zhao, Li L. MiR-148a regulates the growth and apoptosis in pancreatic cancer by targeting CCKBR and Bcl-2. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 35. issue 1. 2014-03-26. PMID:23975374. |
mir-148a was found to not only inhibit the proliferation of pancreatic cancer cells (panc-1 and aspc-1) in vitro by mtt assay and colony formation assay, but also to promote cells apoptosis in vitro by annexin v-fitc apoptosis detection and caspase activity assay. |
2014-03-26 |
2023-08-12 |
Not clear |
| Michelly C Pereira, Simone A de Bessa-Garcia, Ravshan Burikhanov, Ana Carolina Pavanelli, Lourival Antunes, Vivek M Rangnekar, Maria A Naga. Prostate apoptosis response-4 is involved in the apoptosis response to docetaxel in MCF-7 breast cancer cells. International journal of oncology. vol 43. issue 2. 2014-03-20. PMID:23760770. |
cell proliferation assays were performed using mtt and apoptosis was evaluated using acridine orange staining, fluorescence microscopy and flow cytometry. |
2014-03-20 |
2023-08-12 |
Not clear |
| Hui Xue, Yang Chen, Xiaopeng Cai, Lei Zhao, Anning He, Kejun Guo, Xinyu Zhen. The combined effect of survivin-targeted shRNA and emodin on the proliferation and invasion of ovarian cancer cells. Anti-cancer drugs. vol 24. issue 9. 2014-03-18. PMID:23921083. |
a sur-shrna plasmid was constructed and transfected into the ovarian cancer cell lines skov3 and ho8910, and the cells were cultured for 24 h. the cells were then treated with emodin for specific time periods and assessed for viability and apoptosis using the mtt assay and flow cytometry, respectively. |
2014-03-18 |
2023-08-12 |
Not clear |
| Amit K Mittal, Nagendra K Chaturvedi, Rae A Rohlfsen, Payal Gupta, Avadhut D Joshi, Ganapati V Hegde, R Gregory Bociek, Shantaram S Josh. Role of CTLA4 in the proliferation and survival of chronic lymphocytic leukemia. PloS one. vol 8. issue 8. 2014-03-18. PMID:23936412. |
we then evaluated proliferation/survival in these cells using mtt, (3)h-thymidine uptake and annexin-v apoptosis assays. |
2014-03-18 |
2023-08-12 |
Not clear |
| Chao-Ming Hung, Chi-Chang Chang, Chen-Wei Lin, Shun-Yao Ko, Yi-Chiang Hs. Cucurbitacin E as inducer of cell death and apoptosis in human oral squamous cell carcinoma cell line SAS. International journal of molecular sciences. vol 14. issue 8. 2014-03-18. PMID:23965977. |
the present study investigates anti-proliferation (using mtt assay, cue demonstrated cytotoxic activity against sas cell with ic50 values at 3.69 µm) and induced apoptosis of human oral squamous cell carcinoma sas cells after 24 h treatment with cue. |
2014-03-18 |
2023-08-12 |
human |
| Yan-hong Wang, Ke-jin Li, Li Mao, Xin Hu, Wen-jie Zhao, An Hu, Hong-zhen Lian, Wei-juan Zhen. Effects of exogenous zinc on cell cycle, apoptosis and viability of MDAMB231, HepG2 and 293 T cells. Biological trace element research. vol 154. issue 3. 2014-03-14. PMID:23839533. |
in this study, we investigated the influences of a specific concentration range of znso4 on cell cycle and apoptosis by flow cytometry, and cell viability by mtt method in mdamb231, hepg2 and 293 t cell lines. |
2014-03-14 |
2023-08-12 |
Not clear |
| Irshad Ali, Rahul Nanchal, Fouad Husnain, Said Audi, G Ganesh Konduri, John C Densmore, Meetha Medhora, Elizabeth R Jacob. Hypoxia preconditioning increases survival and decreases expression of Toll-like receptor 4 in pulmonary artery endothelial cells exposed to lipopolysaccharide. Pulmonary circulation. vol 3. issue 3. 2014-03-12. PMID:24618542. |
cell apoptosis and survival were measured by caspase 3 activity and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) incorporation. |
2014-03-12 |
2023-08-12 |
cattle |
| Bin He, Xiuyan Huang, Xinyuan Liu, Bin X. Cancer targeting gene-viro-therapy for pancreatic cancer using oncolytic adenovirus ZD55-IL-24 in immune-competent mice. Molecular biology reports. vol 40. issue 9. 2014-03-10. PMID:23666064. |
the in vitro anti pc ability of zd55-il-24 was tested by mtt, crystal violet staining and apoptosis assays. |
2014-03-10 |
2023-08-12 |
mouse |