| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gaurav Kaushik, Toshi Kaushik, Subodh Kumar Yadav, Sanjeev Kumar Sharma, Pavitra Ranawat, Krishan Lal Khanduja, Chander Mohan Patha. Curcumin sensitizes lung adenocarcinoma cells to apoptosis via intracellular redox status mediated pathway. Indian journal of experimental biology. vol 50. issue 12. 2013-09-19. PMID:23986968. |
results indicated that curcumin induced cell toxicity (light microscopy and mtt assay) and apoptosis (annexinv-fitc/pi labeling and caspase-3 activity) in these cells. |
2013-09-19 |
2023-08-12 |
human |
| Yue Sheng, Bo Sun, Wen-Ting Guo, Yong-Hui Zhang, Xiao Liu, Yue Xing, De-Li Don. 3-Methyladenine induces cell death and its interaction with chemotherapeutic drugs is independent of autophagy. Biochemical and biophysical research communications. vol 432. issue 1. 2013-09-16. PMID:23395679. |
cell viability, cell death and cell apoptosis were evaluated by mtt, live and dead assay kit and tunel staining. |
2013-09-16 |
2023-08-12 |
Not clear |
| Jie Xu, Rui Zhang, Pingping Zuo, Nan Yang, Chao Ji, Weiran Liu, Yun Wang, Hui Wang, Anshi Wu, Yun Yue, Yanyong Li. Aggravation effect of isoflurane on Aβ(25-35)-induced apoptosis and tau hyperphosphorylation in PC12 cells. Cellular and molecular neurobiology. vol 32. issue 8. 2013-09-13. PMID:22814802. |
cultured rat pheochromocytoma cells (pc12) were exposed to 20 mm aβ25-35 alone or with 2% isoflurane for 6 h. the cell viability was determined by mtt assay, and the apoptosis rate was detected by flowcytometry. |
2013-09-13 |
2023-08-12 |
rat |
| Zhang Peng, Yue Shuangzhu, Jiang Yongjie, Zhang Xinjun, Liu Yin. TNF receptor-associated factor 6 regulates proliferation, apoptosis, and invasion of glioma cells. Molecular and cellular biochemistry. vol 377. issue 1-2. 2013-09-13. PMID:23358926. |
subsequently, the effects of traf6 on cell viability, cell cycle distribution, apoptosis, invasion, and migration in u-87mg cells were determined with 3-(4,5-dimethylthiazol-2-yl) 2,5-diphenyl tetrazolium bromide (mtt) assay, flow cytometry analysis, transwell invasion assay, and wound-healing assay. |
2013-09-13 |
2023-08-12 |
human |
| John Hoggard, Junming Fan, Zhe Lu, Qun Lu, Leonard Sutton, Yan-Hua Che. Claudin-7 increases chemosensitivity to cisplatin through the upregulation of caspase pathway in human NCI-H522 lung cancer cells. Cancer science. vol 104. issue 5. 2013-09-13. PMID:23433123. |
the cell viability assayed by mtt and annexin v was significantly decreased and cell apoptosis was dramatically increased in claudin-7 transfected cells compared to that of vector transfected cells after cisplatin treatment. |
2013-09-13 |
2023-08-12 |
human |
| Qiang Wang, Li-Hong Li, Guo-Dong Gao, Gang Wang, Liang Qu, Jin-Ge Li, Chun-Mei Wan. HIF-1α up-regulates NDRG1 expression through binding to NDRG1 promoter, leading to proliferation of lung cancer A549 cells. Molecular biology reports. vol 40. issue 5. 2013-09-13. PMID:23526365. |
results from mtt, colony-forming assay and flow cytometry showed that ndrg1 overexpression results in more proliferation and less apoptosis of a549 lung cancer cells. |
2013-09-13 |
2023-08-12 |
Not clear |
| Wenxiang Bi, Yuping Wei, Jinxiang Wu, Gaoying Sun, Yuanfang Guo, Qiang Zhang, Liang Don. MADD promotes the survival of human lung adenocarcinoma cells by inhibiting apoptosis. Oncology reports. vol 29. issue 4. 2013-09-12. PMID:23443411. |
proliferation and apoptosis were detected using mtt assay and flow cytometry, respectively. |
2013-09-12 |
2023-08-12 |
human |
| Ming-Hsien Chien, Tsung-Ho Ying, Shun-Fa Yang, Ji-Kuen Yu, Chih-Wei Hsu, Shu-Ching Hsieh, Yi-Hsien Hsie. Lipocalin-2 induces apoptosis in human hepatocellular carcinoma cells through activation of mitochondria pathways. Cell biochemistry and biophysics. vol 64. issue 3. 2013-09-04. PMID:22707293. |
mtt, dapi, tunel, and flow cytometry analyses revealed that lcn2 overexpression dramatically inhibited cell viability, induced apoptosis features of cell-cycle arrest in sub-g1 phase, in dna fragmentation, and in condensation of chromatin in huh-7 and sk-hep-1 cells. |
2013-09-04 |
2023-08-12 |
human |
| I V Kharchuk, O O Andrukhova, V K Rybal'chenko, O Andrukho. [Mechanisms of nephrotoxicity of novel anticancer compound maleimide derivative MI-1]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994). vol 59. issue 3. 2013-09-03. PMID:23957164. |
the viability and apoptosis of renal epithelial tubular cells after incubation with mi-1 were perfomed by 3,4,5-dymetyltiazol-2-yl-2,5-diphenyl-tetrazolium bromide (mtt)-test and by flow cytometry after staining with specific antibodies to annexin v, respectively. |
2013-09-03 |
2023-08-12 |
Not clear |
| Samantha Licy Stubbs, Sarah Tzu-Feng Hsiao, Hitesh Mahendrabhai Peshavariya, Shiang Yong Lim, Gregory James Dusting, Rodney James Dille. Hypoxic preconditioning enhances survival of human adipose-derived stem cells and conditions endothelial cells in vitro. Stem cells and development. vol 21. issue 11. 2013-08-28. PMID:22165914. |
hpc significantly increased asc viability, and reduced cell injury and apoptosis compared with non-preconditioned cells under ischemic conditions, as shown by 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2h-tetrazolium bromide (mtt), lactate dehydrogenase-release, and caspase activity assays. |
2013-08-28 |
2023-08-12 |
human |
| T W Son, S P Yun, M S Yong, B N Seo, J M Ryu, H Y Youn, Y M Oh, H J Ha. Netrin-1 protects hypoxia-induced mitochondrial apoptosis through HSP27 expression via DCC- and integrin α6β4-dependent Akt, GSK-3β, and HSF-1 in mesenchymal stem cells. Cell death & disease. vol 4. 2013-08-23. PMID:23538444. |
hypoxia (72 h) reduced cell viability (mtt reduction, and [(3)h]-thymidine incorporation) and cell number, and induced apoptosis (annexin and/or pi positive), which were reversed by ntn-1 (10 ng/ml). |
2013-08-23 |
2023-08-12 |
Not clear |
| Sida Qin, Chengcheng Yang, Xifang Wang, Chongwen Xu, Shuo Li, Boxiang Zhang, Hong Re. Overexpression of Smac promotes Cisplatin-induced apoptosis by activating caspase-3 and caspase-9 in lung cancer A549 cells. Cancer biotherapy & radiopharmaceuticals. vol 28. issue 2. 2013-08-15. PMID:23252748. |
subsequently, mtt assays, cell counting, and flow cytometry were applied to show that overexpression of smac inhibits cell viability and cell growth and enhances apoptosis after cisplatin treatment. |
2013-08-15 |
2023-08-12 |
Not clear |
| Yuan Gao, Zan Liu, Xiuwei Zhang, Jiani He, Yongqi Pan, Fengxia Hao, Lingling Xie, Qingchang Li, Xueshan Qiu, Enhua Wan. Inhibition of cytoplasmic GSK-3β increases cisplatin resistance through activation of Wnt/β-catenin signaling in A549/DDP cells. Cancer letters. vol 336. issue 1. 2013-08-15. PMID:23673211. |
the regulation of cisplatin resistance, apoptosis, β-catenin and survivin protein expression by inhibition of cytoplasmic gsk-3β were determined by mtt assay, flow cytometry analysis, immunofluorescence technique and western blot analysis. |
2013-08-15 |
2023-08-12 |
human |
| Shenglei Hou, Hongmei Ma, Yuxuan Ji, Wenyue Hou, Nengqin Ji. A calcium phosphate nanoparticle-based biocarrier for efficient cellular delivery of antisense oligodeoxynucleotides. ACS applied materials & interfaces. vol 5. issue 3. 2013-08-12. PMID:23323641. |
furthermore, cellular uptake and delivery efficiency of the asodns-cpnps, as well as cellular apoptosis induced by the asodns doping into the calcium phosphate nanoparticles, were investigated by confocal laser scanning microscopy, biological tem, flow cytometry, and mtt assay. |
2013-08-12 |
2023-08-12 |
Not clear |
| Guofang Feng, Xiaoqing Wang, Changxuan You, Xiaohua Cheng, Zeli Han, Liang Zong, Chengyong Zhou, Meikui Zhan. Antiproliferative potential of Artemisia capillaris polysaccharide against human nasopharyngeal carcinoma cells. Carbohydrate polymers. vol 92. issue 2. 2013-08-01. PMID:23399126. |
mtt and flow cytometric analysis identified that wacp had a potent anti-proliferation activity on cne-2 cells by inducing apoptosis, which was parallel with the morphological changes of cne-2 cells under inverted microscope. |
2013-08-01 |
2023-08-12 |
human |
| Se-Lim Kim, Seong Hun Kim, Kieu Thi Thu Trang, In Hee Kim, Seung-Ok Lee, Soo Teik Lee, Dae Ghon Kim, Sang-Beom Kang, Sang-Wook Ki. Synergistic antitumor effect of 5-fluorouracil in combination with parthenolide in human colorectal cancer. Cancer letters. vol 335. issue 2. 2013-07-30. PMID:23507557. |
the results demonstrated that combination of pt and 5-fu induced apoptosis which was determined using mtt, cell cycle analysis, annexin-v assay, and hoechst 33258 staining. |
2013-07-30 |
2023-08-12 |
human |
| Xiaowen Pang, Jie Min, Lili Liu, Yi Liu, Ningqiang Ma, Helong Zhan. S100B protein as a possible participant in the brain metastasis of NSCLC. Medical oncology (Northwood, London, England). vol 29. issue 4. 2013-07-26. PMID:22286962. |
mtt and flow cytometric analysis showed that s100b transfection promoted cell proliferation and inhibited cell apoptosis (p<0.05). |
2013-07-26 |
2023-08-12 |
human |
| Li Zhao, Yuping Xiao, Nan Xia. Effect of lentinan combined with docetaxel and cisplatin on the proliferation and apoptosis of BGC823 cells. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 34. issue 3. 2013-07-18. PMID:23404406. |
tetrazolium-based colorimetric assay (mtt), annexin v/propidium iodide method and flow cytometry were used to determine the proliferation and apoptosis of the cells in each group. |
2013-07-18 |
2023-08-12 |
Not clear |
| V Lisiansky, I Naumov, S Shapira, D Kazanov, A Starr, N Arber, S Krau. Gene therapy of pancreatic cancer targeting the K-Ras oncogene. Cancer gene therapy. vol 19. issue 12. 2013-07-17. PMID:23099885. |
cell viability was estimated by 3-(4, 5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) and apoptosis was evaluated by facs. |
2013-07-17 |
2023-08-12 |
mouse |
| Ananya Datta Mitra, Siba P Raychaudhuri, Christine J Abria, Anupam Mitra, Rebecca Wright, Rahul Ray, Smriti Kundu-Raychaudhur. 1α,25-Dihydroxyvitamin-D3-3-bromoacetate regulates AKT/mTOR signaling cascades: a therapeutic agent for psoriasis. The Journal of investigative dermatology. vol 133. issue 6. 2013-07-17. PMID:23314787. |
proliferation and apoptosis studies in normal human epidermal keratinocytes (nheks) were conducted by mtt (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide), cfse (carboxy fluorescein succinimidyl ester) dilution, and annexin v assays. |
2013-07-17 |
2023-08-12 |
human |