| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Z-W Fei, M-K Qiu, X-Q Qi, Y-X Dai, S-Q Wang, Z-W Quan, Y-B Liu, J-M O. Oxymatrine suppresses proliferation and induces apoptosis of hemangioma cells through inhibition of HIF-1a signaling. International journal of immunopathology and pharmacology. vol 28. issue 2. 2017-04-04. PMID:25816398. |
after ha derived endothelial cells (hdec) were pretreated with different concentrations of omt, cell proliferation, apoptosis, and cycle distribution were evaluated by mtt assay and flow cytometry analysis, respectively. |
2017-04-04 |
2023-08-13 |
human |
| Hong Li, Xiaowen Zhang, Xuejun Jiang, Xu J. The expression and function of epithelial membrane protein 1 in laryngeal carcinoma. International journal of oncology. vol 50. issue 1. 2017-04-04. PMID:27909719. |
furthermore, we ectopically expressed emp1 in human laryngeal carcinoma hep-2 cells and examined the effects on cell viability, apoptosis, colonogenicity, and motility, by mtt assay, flow cytometry, colony formation assay and transwell migration assay, respectively. |
2017-04-04 |
2023-08-13 |
human |
| Bi Liu, Ming Lei, Tao Hu, Fei Yu, De-Ming Xiao, Hao Kan. Inhibitory effects of SRT1720 on the apoptosis of rabbit chondrocytes by activating SIRT1 via p53/bax and NF-κB/PGC-1α pathways. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 36. issue 3. 2017-04-03. PMID:27376802. |
mtt assay was used to detect the chondrocyte viability and proliferation, and dapi staining and flow cytometry to measure the chondrocyte apoptosis. |
2017-04-03 |
2023-08-13 |
rabbit |
| Qin Yu, Zhao-Yu Liu, Qiong Chen, Ju-Sheng Li. Mcl-1 as a potential therapeutic target for human hepatocelluar carcinoma. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 36. issue 4. 2017-04-03. PMID:27465322. |
cell viability and apoptosis were assessed by mtt and facs analysis. |
2017-04-03 |
2023-08-13 |
human |
| Jing-Yu Liu, Feng Guo, Hong-Ling Wu, Ying Wang, Jin-Shan Li. Midazolam anesthesia protects neuronal cells from oxidative stress-induced death via activation of the JNK-ERK pathway. Molecular medicine reports. vol 15. issue 1. 2017-04-03. PMID:27959401. |
subsequently, cell viability was detected using the mtt assay; intracellular reactive oxygen species (ros) generation was determined using the 2',7'‑dichlorodihydrofluorescein diacetate method with confocal microscopy; terminal deoxynucleotidyl transferase dutp nick end labeling (tunel) staining was conducted to detect apoptotic cells; immunohistochemistry was performed to detect activated caspase‑3; neuronal deficit and infarct volume analyses were conducted; and quantitative polymerase chain reaction and western blotting were performed to detect the expression levels of genes and proteins associated with apoptosis and cell survival pathways. |
2017-04-03 |
2023-08-13 |
mouse |
| Yang Liu, Liumi Jiang, Xiaofeng L. κ‑carrageenan‑derived pentasaccharide attenuates Aβ25‑35‑induced apoptosis in SH‑SY5Y cells via suppression of the JNK signaling pathway. Molecular medicine reports. vol 15. issue 1. 2017-04-03. PMID:27959440. |
the results of the present study revealed that pretreatment with kcp significantly attenuated aβ25‑35‑induced loss of cell viability and apoptosis, as evaluated by mtt assays and annexin v/propidium iodide staining, respectively, in a dose‑dependent manner. |
2017-04-03 |
2023-08-13 |
Not clear |
| Do Rim Kim, Ji Eun Lee, Kyung Jun Shim, Jin Hyoung Cho, Ho Chul Lee, Seong Kyu Park, Mun Seog Chan. Effects of herbal Epimedium on the improvement of bone metabolic disorder through the induction of osteogenic differentiation from bone marrow-derived mesenchymal stem cells. Molecular medicine reports. vol 15. issue 1. 2017-03-31. PMID:27959402. |
the present study was performed to investigate the effects of he on mouse bone marrow mesenchymal stem cell (mbmmsc) proliferation and osteogenic differentiation, using mtt assays, proliferating cell nuclear antigen (pcna) detection and apoptosis and differentiation assays. |
2017-03-31 |
2023-08-13 |
mouse |
| Koji Harada, Tarannum Ferdous, Toyoko Harada, Yoshiya Ueyam. Metformin in combination with 5-fluorouracil suppresses tumor growth by inhibiting the Warburg effect in human oral squamous cell carcinoma. International journal of oncology. vol 49. issue 1. 2017-03-30. PMID:27210058. |
mtt assay and tunel assay revealed that metformin (4 mg/ml) and 5-fu (2.5 µg/ml) combination treatment effectively inhibited cell growth and induced apoptosis in oscc cell lines (hsc2, hsc3 and hsc4) compared to either agent alone. |
2017-03-30 |
2023-08-13 |
mouse |
| Han Wang, Weiwei Ga. DJ-1 Expression in Cervical Carcinoma and its Effects on Cell Viability and Apoptosis. Medical science monitor : international medical journal of experimental and clinical research. vol 22. 2017-03-27. PMID:27544688. |
dj-1 was interfered and transfected with sirna, then cell viability and apoptosis were assayed by mtt and flow cytometry, respectively. |
2017-03-27 |
2023-08-13 |
Not clear |
| Xiaodong Bi, Yu Cao, Rixin Chen, Chengyin Liu, Jinghong Chen, Dongfang Mi. MicroRNA-184 Promotes Proliferation and Inhibits Apoptosis in HaCaT Cells: An In Vitro Study. Medical science monitor : international medical journal of experimental and clinical research. vol 22. 2017-03-27. PMID:27571235. |
the mir-184 was transfected with sirna, then cell viability and apoptosis were assayed by mtt and flow cytometry, respectively. |
2017-03-27 |
2023-08-13 |
Not clear |
| Yongbin Wang, Weiqiang Kang, Xu Wang, Meina Chen, Qiaoji Qin, Minglei Guo, Zhiming G. Functional Role and Mechanism of microRNA-28b in Atrial Myocyte in a Persistent Atrial Fibrillation Rat Model. Medical science monitor : international medical journal of experimental and clinical research. vol 22. 2017-03-27. PMID:27574952. |
cardiomyocytes were isolated and cultured to detect cell proliferation and apoptosis by mtt and flow cytometry, respectively. |
2017-03-27 |
2023-08-13 |
rat |
| Xianglian Liu, Pu Guo, Aimei Liu, Qinghua Wu, Xijuan Xue, Menghong Dai, Haihong Hao, Wei Qu, Shuyu Xie, Xu Wang, Zonghui Yua. Nitric oxide (NO)-mediated mitochondrial damage plays a critical role in T-2 toxin-induced apoptosis and growth hormone deficiency in rat anterior pituitary GH3 cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 102. 2017-03-27. PMID:28130091. |
herein, t-2 toxin-induced gh3 cell damage and apoptosis were tested by mtt assay, ldh leakage and flow cytometry, respectively. |
2017-03-27 |
2023-08-13 |
human |
| Panshi Zhang, Xiaowei Yang, Qian Yin, Jilin Yi, Wenzhuang Shen, Lu Zhao, Zhi Zhu, Jinwen Li. Inhibition of SK4 Potassium Channels Suppresses Cell Proliferation, Migration and the Epithelial-Mesenchymal Transition in Triple-Negative Breast Cancer Cells. PloS one. vol 11. issue 4. 2017-03-24. PMID:27124117. |
by employing sk4 specific sirnas and blockers, including tram-34 and clotrimazole, in combination with an mtt assay, a colony-formation assay, flow cytometry and a cell motility assay, we found that the suppression of sk4 channels significantly inhibited cell proliferation and migration and promoted apoptosis in mda-mb-231 cells (p<0.05). |
2017-03-24 |
2023-08-13 |
Not clear |
| Tianhui Wu, Xin Chen, Rui Peng, Handeng Liu, Pin Yin, Huimin Peng, Yujian Zhou, Yan Sun, Li Wen, Hong Yi, Ailing Li, Zheng Zhan. Let‑7a suppresses cell proliferation via the TGF‑β/SMAD signaling pathway in cervical cancer. Oncology reports. vol 36. issue 6. 2017-03-24. PMID:27748903. |
cell proliferation was tested by mtt assay, and cell apoptosis and cell cycle were examined by flow cytometric analysis in hela cells. |
2017-03-24 |
2023-08-13 |
human |
| Yudan Cao, Fangfang Cheng, Weifeng Yao, Beihua Bao, Kaicheng Zhang, Li Zhang, Anwei Din. Toxicity of Pekinenin C from Euphorbia Pekinensis Radix on Rat Small Intestinal Crypt Epithelial Cell and Its Apoptotic Mechanism. International journal of molecular sciences. vol 17. issue 6. 2017-03-21. PMID:27271594. |
the proliferation of iec-6 cells was accessed via mtt colorimetric assay after incubated with different concentrations of pekinenin c. pekinenin c-treated iec-6 cells labeled with rnase/pi and annexin v/pi were analyzed by flow cytometric analyses for evaluation of cell cycle distribution and cell apoptosis, respectively. |
2017-03-21 |
2023-08-13 |
rat |
| Xiaohui Zhang, Xiaohua Zhang, Yiqun Xiong, Chaoying Xu, Xinliang Liu, Jian Lin, Guiping Mu, Shaogang Xu, Wenhe Li. Sarcolemmal ATP-sensitive potassium channel protects cardiac myocytes against lipopolysaccharide-induced apoptosis. International journal of molecular medicine. vol 38. issue 3. 2017-03-21. PMID:27430376. |
the tunel assay was performed in order to detect the apoptosis of cardiac myocytes and the mtt assay was performed to determine cellular viability. |
2017-03-21 |
2023-08-13 |
rat |
| Mohammed A Suliman, Zhenxing Zhang, Heya Na, Ailton L L Ribeiro, Yu Zhang, Bachir Niang, Abdu Salim Hamid, Hua Zhang, Lijie Xu, Yunfei Zu. Niclosamide inhibits colon cancer progression through downregulation of the Notch pathway and upregulation of the tumor suppressor miR-200 family. International journal of molecular medicine. vol 38. issue 3. 2017-03-21. PMID:27460529. |
by performing mtt, wound-healing and transwell migration assays, we observed that niclosamide suppressed the growth and migration of colon cancer cells, and flow cytometry demonstrated that cell apoptosis was induced. |
2017-03-21 |
2023-08-13 |
Not clear |
| Changqing Pan, Dan Wang, Yao Zhang, Wenliang Y. MicroRNA-1284 Inhibits Cell Viability and Induces Apoptosis of Ovarian Cancer Cell Line OVCAR3. Oncology research. vol 24. issue 6. 2017-03-21. PMID:28281963. |
viability and apoptosis of transfected cells were then determined by mtt assay, brdu assay, and flow cytometry. |
2017-03-21 |
2023-08-13 |
human |
| Jian Zhang, ZhenFeng Shi, JinXing Huang, XiaoGuang Zo. CSTB Downregulation Promotes Cell Proliferation and Migration and Suppresses Apoptosis in Gastric Cancer SGC-7901 Cell Line. Oncology research. vol 24. issue 6. 2017-03-21. PMID:28281969. |
moreover, mtt assay, transwell assay, and flow cytometry were used to assess cell proliferation, migration, and apoptosis, respectively. |
2017-03-21 |
2023-08-13 |
human |
| Meijuan Liu, Wanli Sun, Yongquan Liu, Xiuhong Don. The role of lncRNA MALAT1 in bone metastasis in patients with non-small cell lung cancer. Oncology reports. vol 36. issue 3. 2017-03-17. PMID:27431200. |
the proliferation ability was assessed by mtt assay, and the apoptosis, migration, invasion and tumorigenesis in vivo were also assessed to detect the effect of malat1 expression on nsclc cells. |
2017-03-17 |
2023-08-13 |
Not clear |