| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| De Jiao, Xue Dong Zhan. Myricetin suppresses p21-activated kinase 1 in human breast cancer MCF-7 cells through downstream signaling of the β-catenin pathway. Oncology reports. vol 36. issue 1. 2017-03-03. PMID:27122002. |
in the present study, we found that myricetin suppressed the cell viability of the mcf-7 cells at least partly through the induction of apoptosis as determined by mtt assay and flow cytometry. |
2017-03-03 |
2023-08-13 |
human |
| Jinfeng Han, Zhongmin Liu, Nanya Wang, Weiyun Pa. MicroRNA-874 inhibits growth, induces apoptosis and reverses chemoresistance in colorectal cancer by targeting X-linked inhibitor of apoptosis protein. Oncology reports. vol 36. issue 1. 2017-03-03. PMID:27221209. |
mtt and colony formation assays and flow cytometry were performed to analyze the effects of mir-874 expression on growth, apoptosis and the chemoresistance of crc cells. |
2017-03-03 |
2023-08-13 |
human |
| Haiji Wang, Duanye Ma, Chenghong Wang, Shanna Zhao, Chengbiao Li. Triptolide Inhibits Invasion and Tumorigenesis of Hepatocellular Carcinoma MHCC-97H Cells Through NF-κB Signaling. Medical science monitor : international medical journal of experimental and clinical research. vol 22. 2017-03-03. PMID:27239780. |
we detected cell survival and apoptosis by mtt, soft-agar colony formation assay, flow cytometry, and tunel assay. |
2017-03-03 |
2023-08-13 |
mouse |
| Elham Farhadi, Farhad Zaker, Majid Safa, Mohammad Reza Rezvan. miR-101 sensitizes K562 cell line to imatinib through Jak2 downregulation and inhibition of NF-κB target genes. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 10. 2017-02-28. PMID:27517565. |
our results also indicated that mir-101 overexpression inhibited cell proliferation indicated by the mtt assay and promoted apoptosis detected via flow cytometry. |
2017-02-28 |
2023-08-13 |
Not clear |
| Xin-Fang Sun, Jin-Ping Sun, Hong-Tao Hou, Ke Li, Xin Liu, Quan-Xing G. MicroRNA-27b exerts an oncogenic function by targeting Fbxw7 in human hepatocellular carcinoma. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 11. 2017-02-28. PMID:27704356. |
mtt, 5-bromodeoxyuridine (brdu) proliferation assays, and flow cytometry analysis were carried out to assay proliferation, cell cycle, and apoptosis. |
2017-02-28 |
2023-08-13 |
mouse |
| Haisong Xu, Yanxia Hu, Wusi Qi. Potential mechanisms of microRNA-129-5p in inhibiting cell processes including viability, proliferation, migration and invasiveness of glioblastoma cells U87 through targeting FNDC3B. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 87. 2017-02-24. PMID:28068630. |
mtt, colony formation, flow cytometry, transwell and wound healing assays were used to analyze cell viability, proliferation, apoptosis, invasiveness and migration. |
2017-02-24 |
2023-08-13 |
Not clear |
| Xuan Kan, Yanan Sun, Jianguang Lu, Minghua Li, Yu Wang, Qiuying Li, Ying Liu, Ming Liu, Linli Tia. Co‑inhibition of miRNA‑21 and miRNA‑221 induces apoptosis by enhancing the p53‑mediated expression of pro‑apoptotic miRNAs in laryngeal squamous cell carcinoma. Molecular medicine reports. vol 13. issue 5. 2017-02-21. PMID:27035337. |
methyl thiazolyl tetrazolium (mtt) and terminal deoxynucleotidyl‑transferase‑mediated deoxynucleotide triphosphate nick end labeling (tunel) assays were used to observe the potential effect of mir‑21 and mir‑221 on cell viability and apoptosis in cells co‑transfected with anti‑mirna oligonucleotide (amo)‑21 and amo‑221. |
2017-02-21 |
2023-08-13 |
human |
| Wenli Cui, Shutao Zheng, Xinxia Li, Yuqing Ma, Wei Sang, Ming Liu, Wei Zhang, Xiaoyan Zho. PIK3CD promoted proliferation in diffuse large B cell lymphoma through upregulation of c-myc. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 9. 2017-02-21. PMID:27448819. |
mtt assay and flow cytometry were employed to evaluate the proliferative variation, cell cycle, and apoptosis. |
2017-02-21 |
2023-08-13 |
mouse |
| Yunxia Li, Suqin Wu, Yuxuan Li, Shenyi Jiang, Tiantian Lin, Liping Xia, Hui Shen, Jing L. Interleukin-35 (IL-35) inhibits proliferation and promotes apoptosis of fibroblast-like synoviocytes isolated from mice with collagen-induced arthritis. Molecular biology reports. vol 43. issue 9. 2017-02-20. PMID:27379996. |
the mtt assay was used to examine fls proliferation, and apoptosis frequency of fls was detected by flow cytometry. |
2017-02-20 |
2023-08-13 |
mouse |
| Hongli Hou, Weipeng Xing, Wuyin L. Brahma-related gene 1 induces apoptosis in a p53-dependent manner in human rheumatoid fibroblast-like synoviocyte MH7A. Medicine. vol 95. issue 51. 2017-02-17. PMID:28002318. |
cell viability and apoptosis were detected by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay and flow cytometry after transfection. |
2017-02-17 |
2023-08-13 |
human |
| Bi-Bo Tan, Ming-Ming Zhang, Yong Li, Qun Zhao, Li-Qiao Fan, Yu Liu, Dong Wan. Inhibition of Vav3 gene can promote apoptosis of human gastric cancer cell line MGC803 by regulating ERK pathway. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 6. 2017-02-16. PMID:26695150. |
vav3-sirna was transfected into mgc803 cells, and then cell activity and apoptosis rate were tested with mtt and fcm; apoptosis-related genes and proteins in mapk signaling pathway were also tested. |
2017-02-16 |
2023-08-13 |
human |
| Enze Li, Zheng Hu, Yi Sun, Qi Zhou, Bin Yang, Zhiguo Zhang, Wenwu Ca. Small molecule inhibitor of c-Met (PHA665752) suppresses the growth of ovarian cancer cells and reverses cisplatin resistance. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 6. 2017-02-16. PMID:26695152. |
the methyl thiazolyl tetrazolium (mtt) assay was used to detect cell proliferation, and apoptosis was evaluated by flow cytometry. |
2017-02-16 |
2023-08-13 |
human |
| Rupeng Zhang, Fangxuan Li, Weijia Wang, Xuejun Wang, Shixia Li, Juntian Li. The effect of antisense inhibitor of miRNA 106b∼25 on the proliferation, invasion, migration, and apoptosis of gastric cancer cell. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 8. 2017-02-15. PMID:26850596. |
after mirna 106b∼25 cluster was inhibited, mtt, scratch test, transwell invasion test, and flow cytometry were applied to investigate the proliferation, invasion, migration, cell cycle, and apoptosis of gastric cancer cell. |
2017-02-15 |
2023-08-13 |
Not clear |
| Ivyna Pau Ni Bong, Ching Ching Ng, Shaik Kamal Fakiruddin, Moon Nian Lim, Zubaidah Zakari. Small interfering RNA-mediated silencing of nicotinamide phosphoribosyltransferase (NAMPT) and lysosomal trafficking regulator (LYST) induce growth inhibition and apoptosis in human multiple myeloma cells: A preliminary study. Bosnian journal of basic medical sciences. vol 16. issue 4. 2017-02-15. PMID:27754828. |
cell proliferation was determined using mtt assay, while apoptosis was analyzed with flow cytometry using annexin v-fluorescein isothiocyanate/propidium iodide assay. |
2017-02-15 |
2023-08-13 |
human |
| Chao-Chiang Tu, Chien-Yu Huang, Wan-Li Cheng, Chin-Sheng Hung, Yu-Jia Chang, Po-Li We. Silencing A7-nAChR levels increases the sensitivity of gastric cancer cells to ixabepilone treatment. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 7. 2017-02-14. PMID:26790437. |
the cytotoxicity of ixabepilone was determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay and ixabepilone-induced apoptosis was analyzed by flow cytometry and annexin v/propidium iodide (pi) apoptotic assay. |
2017-02-14 |
2023-08-13 |
Not clear |
| Gebang Wang, Huan Wang, Chenlei Zhang, Tieqin Liu, Qingchang Li, Xuyong Lin, Jingwei Xie, Hongxu Li. Rac3 regulates cell proliferation through cell cycle pathway and predicts prognosis in lung adenocarcinoma. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 9. 2017-02-14. PMID:27402308. |
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay, colony formation assay, and flow cytometry analysis were employed to determine the proliferative ability, cell cycle distribution, and apoptosis in h1299 and h1975 cell lines. |
2017-02-14 |
2023-08-13 |
Not clear |
| Ronghe Gu, Ning Liu, Simin Luo, Weiguo Huang, Zhengang Zha, Jie Yan. MicroRNA-9 regulates the development of knee osteoarthritis through the NF-kappaB1 pathway in chondrocytes. Medicine. vol 95. issue 36. 2017-02-14. PMID:27603333. |
knee oa chondrocytes were transfected with mir-9 mimics, mir-9 inhibitor, and nf-κb1 sirna, respectively, and changes in cellular proliferation and apoptosis were detected via mtt assay and flow cytometric analysis, respectively. |
2017-02-14 |
2023-08-13 |
human |
| Haoyuan Yin, Ying Shao, Xuan Che. The effects of CD147 on the cell proliferation, apoptosis, invasion, and angiogenesis in glioma. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 38. issue 1. 2017-02-14. PMID:27761842. |
cell proliferation, apoptosis, invasion, and angiogenesis were tested by mtt, flow cytometry, transwell assay, and vasculogenic mimicry assay, respectively. |
2017-02-14 |
2023-08-13 |
human |
| Zhi-Ming Wang, Dong-Sheng Yang, Jie Liu, Hong-Bo Liu, Ming Ye, Yu-Fei Zhan. ROCK inhibitor Y-27632 inhibits the growth, migration, and invasion of Tca8113 and CAL-27 cells in tongue squamous cell carcinoma. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 3. 2017-02-13. PMID:26468018. |
the morphological change of y-27632-treated cells was observed under an optical microscope and an inverted microscope; mtt assay was performed to measure the optical density (od) of cells and calculate cell growth inhibition rate; the change of apoptosis was detected by annexinv-fitc/pi assay; cell invasion and migration were measured by transwell assay. |
2017-02-13 |
2023-08-13 |
Not clear |
| Zhi-Ming Wang, Dong-Sheng Yang, Jie Liu, Hong-Bo Liu, Ming Ye, Yu-Fei Zhan. ROCK inhibitor Y-27632 inhibits the growth, migration, and invasion of Tca8113 and CAL-27 cells in tongue squamous cell carcinoma. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 3. 2017-02-13. PMID:26468018. |
the results were as follows: (1) with increasing concentration of y-27632, cell morphology changed and cell apoptosis appeared; (2) mtt assay showed that inhibition effect of y-27632 on tca8113 and cal-27 cells was enhanced with increasing concentrations and time (all p < 0.01); (3) apoptosis showed that, compared with controls, the number of apoptosis cells in experimental groups was significantly increased (all p < 0.01). |
2017-02-13 |
2023-08-13 |
Not clear |