| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hua Wang, Jinlin W. 17β-estradiol suppresses hyperoxia-induced apoptosis of oligodendrocytes through paired-immunoglobulin-like receptor B. Molecular medicine reports. vol 13. issue 3. 2017-01-03. PMID:26821234. |
prib was silenced with small interfering (si)rna and the effects of e2 treatment and silencing of prib on the viability and apoptosis of opcs under hyperoxic stimulation was detected using 3‑(4,5‑dimethyl‑2‑thiazolyl)‑2,5‑diphenyl‑2‑h‑tetrazoliu‑bromide (mtt) assay and flow cytometry analysis. |
2017-01-03 |
2023-08-13 |
rat |
| Jian Zhao, Wenjia Nie, Wei Li, Xiaohui Zhou, Huifeng Sun, Junqing Zhu, Jinjun Chen, Junlu Pen. [Interferon-β combined with all-trans retinoic acid supresses proliferation and promote apoptosis by inhibiting JAK2/STAT3 pathway in HepG2 human hepatocellular carcinoma cells]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 32. issue 7. 2017-01-03. PMID:27363269. |
cell viability was measured by mtt assay and apoptosis rate was detected by flow cytometry. |
2017-01-03 |
2023-08-13 |
human |
| Nien-Cheng Chen, Charng-Cherng Chyau, Yi-Ju Lee, Hsien-Chun Tseng, Fen-Pi Cho. Promotion of mitotic catastrophe via activation of PTEN by paclitaxel with supplement of mulberry water extract in bladder cancer cells. Scientific reports. vol 6. 2017-01-02. PMID:26838546. |
treatment with paclitaxel combined with mwe (paclitaxel/mwe) enhanced the cytotoxicity of paclitaxel and induced severe g2/m arrest, mitotic catastrophe and subsequent apoptosis, as shown by mtt assay, he staining and flow cytometry analyses. |
2017-01-02 |
2023-08-13 |
human |
| Yifan Li, Tiantian Wang, Yuchi Li, Duqun Chen, Zuhu Yu, Lu Jin, Liangchao Ni, Shangqi Yang, Xiangming Mao, Yaoting Gui, Yongqing La. Identification of long-non coding RNA UCA1 as an oncogene in renal cell carcinoma. Molecular medicine reports. vol 13. issue 4. 2016-12-28. PMID:26935146. |
the impact of uca1 on cell migration, proliferation and apoptosis was investigated by wound scratch assay, mtt and flow cytometry, respectively. |
2016-12-28 |
2023-08-13 |
human |
| Xuxia Tang, Chen Zhang, Jiongzhou Wei, Yuting Fang, Rongxiang Zhao, Jianxin Y. Apoptosis is induced by shikonin through the mitochondrial signaling pathway. Molecular medicine reports. vol 13. issue 4. 2016-12-28. PMID:26935754. |
mtt, annexin v‑phycoerythrin/7‑aminoactinomycin d staining, electron microscopy and jc‑1 probe staining were performed to analyze mitochondrial membrane potential, and western blot analysis was used to examine the activation of the mitochondrial signaling pathway, and the changes in mitochondrial apoptosis pathway‑associated protein expression. |
2016-12-28 |
2023-08-13 |
human |
| Xiaolei Lin, Yiqun Huang, Yong Zou, Xingsheng Chen, Xudong M. Depletion of G9a gene induces cell apoptosis in human gastric carcinoma. Oncology reports. vol 35. issue 5. 2016-12-27. PMID:27081761. |
cell apoptosis and proliferation were detected by tunel assay and mtt, respectively. |
2016-12-27 |
2023-08-13 |
human |
| Tianze Zhang, Yingying Hu, Jin Ju, Liangyu Hou, Zhange Li, Dan Xiao, Yongchao Li, Jianyu Yao, Chao Wang, Yong Zhang, Linyou Zhan. Downregulation of miR-522 suppresses proliferation and metastasis of non-small cell lung cancer cells by directly targeting DENN/MADD domain containing 2D. Scientific reports. vol 6. 2016-12-26. PMID:26783084. |
furthermore, an mtt assay, 5-ethynyl-2'-deoxyuridine (edu) assay kit and flow cytometry confirmed that the inhibition of mir-522 suppressed nsclc cells proliferation and induced apoptosis. |
2016-12-26 |
2023-08-13 |
human |
| Jin-Yan Zhang, Ming-Zhe Weng, Fang-Bin Song, Yong-Gang Xu, Qi Liu, Jun-Yi Wu, Jun Qin, Tao Jin, Jun-Ming X. Long noncoding RNA AFAP1-AS1 indicates a poor prognosis of hepatocellular carcinoma and promotes cell proliferation and invasion via upregulation of the RhoA/Rac2 signaling. International journal of oncology. vol 48. issue 4. 2016-12-26. PMID:26892468. |
the effect of afap1-as1 on cell proliferation was examined by mtt assay, cell apoptosis was detected by flow cytometric analysis and cell invasion was determined by transwell assay. |
2016-12-26 |
2023-08-13 |
mouse |
| Junpu Wang, Wanming Hu, Xiaoying Wu, Kuansong Wang, Jun Yu, Baihua Luo, Gengqiu Luo, Weiyuan Wang, Huiling Wang, Jinghe Li, Jifang We. CXCR1 promotes malignant behavior of gastric cancer cells in vitro and in vivo in AKT and ERK1/2 phosphorylation. International journal of oncology. vol 48. issue 5. 2016-12-26. PMID:26983663. |
malignant behavior was evaluated in vitro for changes in proliferation by mtt and colony forming assays; cell cycle and apoptosis by flow cytometry; and migration and invasion using transwell and wound-healing assays. |
2016-12-26 |
2023-08-13 |
mouse |
| Shi-Qi Fang, Yong-Tang Wang, Jing-Xiang Wei, Ya-Hai Shu, Lan Xiao, Xiu-Min L. Beneficial effects of chlorogenic acid on alcohol-induced damage in PC12 cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 79. 2016-12-26. PMID:27044836. |
in order to investigate the protective effects of ca on alcohol-induced apoptosis in rat pheochromocytoma pc12 cells, in the present study, cell viability and the optimal dosage of ca were first quantified by mtt assay. |
2016-12-26 |
2023-08-13 |
rat |
| Ryota Kurimoto, Shunichiro Iwasawa, Takahiro Ebata, Tsukasa Ishiwata, Ikuo Sekine, Yuji Tada, Koichiro Tatsumi, Shuhei Koide, Atsushi Iwama, Yuichi Takiguch. Drug resistance originating from a TGF-β/FGF-2-driven epithelial-to-mesenchymal transition and its reversion in human lung adenocarcinoma cell lines harboring an EGFR mutation. International journal of oncology. vol 48. issue 5. 2016-12-21. PMID:26984042. |
chemosensitivity to gefitinib and cisplatin was evaluated using an mtt assay and apoptosis. |
2016-12-21 |
2023-08-13 |
human |
| Wei Shen, Bingfeng Liang, Jie Yin, Xiurong Li, Jianxin Chen. Noscapine Increases the Sensitivity of Drug-Resistant Ovarian Cancer Cell Line SKOV3/DDP to Cisplatin by Regulating Cell Cycle and Activating Apoptotic Pathways. Cell biochemistry and biophysics. vol 72. issue 1. 2016-12-19. PMID:25510462. |
cell proliferation was measured by mtt assay, flow cytometry was used to analyze cell cycle and apoptosis, protein expression of several apoptotic factors was investigated by flow cytometry and immunohistochemical method, and their mrna expression levels were determined by real-time pcr. |
2016-12-19 |
2023-08-13 |
mouse |
| Wenchao Zhou, Aili Cao, Li Wang, Dazheng W. Kurarinone Synergizes TRAIL-Induced Apoptosis in Gastric Cancer Cells. Cell biochemistry and biophysics. vol 72. issue 1. 2016-12-19. PMID:25524636. |
after the cells were treated with trail and/or kurarinone, the cell viability and apoptosis were examined by mtt and flow cytometry, respectively. |
2016-12-19 |
2023-08-13 |
human |
| S A Ferraro, F Astort, J S Yakisich, D R Tasa. Particulate matter cytotoxicity in cultured SH-SY5Y cells is modulated by simvastatin: Toxicological assessment for oxidative damage. Neurotoxicology. vol 53. 2016-12-19. PMID:26773838. |
we evaluated cell viability by the mtt assay, superoxide anion generation by nbt test, nrf2 activation by immunofluorescence, apoptosis by cleaved-parp and active-caspase 3 expressions, and senescence by β-galactosidase activity. |
2016-12-19 |
2023-08-13 |
human |
| Quan-Guang Ren, Sheng-Li Yang, Jian-Li Hu, Pin-Dong Li, Ye-Shan Chen, Qiu-Shuang Wan. Evaluation of HO-1 expression, cellular ROS production, cellular proliferation and cellular apoptosis in human esophageal squamous cell carcinoma tumors and cell lines. Oncology reports. vol 35. issue 4. 2016-12-19. PMID:26780849. |
cell line viability, apoptosis and intracellular levels of reactive oxygen species (ros) after transfection were determined using mtt and flow cytometry, respectively. |
2016-12-19 |
2023-08-13 |
human |
| Ranran Kong, Jie Feng, Yuefeng Ma, Bin Zhou, Shaomin Li, Wei Zhang, Jiantao Jiang, Jin Zhang, Zhe Qiao, Ting Zhang, Quanjin Zang, Xijing H. Silencing NACK by siRNA inhibits tumorigenesis in non-small cell lung cancer via targeting Notch1 signaling pathway. Oncology reports. vol 35. issue 4. 2016-12-19. PMID:26782286. |
mtt assay, cell migration assay, cell invasion assay, flow cytometry assay, and xenograft model were employed to detect the effect of nack knockdown on the cell proliferation, metastasis, invasion and apoptosis of nsclc. |
2016-12-19 |
2023-08-13 |
Not clear |
| Z W Wu, Y F Liu, S Wang, B L. miRNA-146a induces vascular smooth muscle cell apoptosis in a rat model of coronary heart disease via NF-κB pathway. Genetics and molecular research : GMR. vol 14. issue 4. 2016-12-19. PMID:26782520. |
the proliferation, growth, apoptosis, and activation of the nf-κb pathway in the vascular smooth muscle cells were detected using the mtt assay and flow cytometry, respectively. |
2016-12-19 |
2023-08-13 |
rat |
| Ruitao Zhang, Huirong Shi, Fang Ren, Xia Li, Minghui Zhang, Wei Feng, Yanyan Ji. Knockdown of MACC1 expression increases cisplatin sensitivity in cisplatin-resistant epithelial ovarian cancer cells. Oncology reports. vol 35. issue 4. 2016-12-19. PMID:26794135. |
different concentrations of cispaltin (0, 10, 20, 30, 40, 50 and 60 µmol/l) were used to treat the cell groups, respectively, and then the chemosensitivity of cisplatin and cell apoptosis were examined by mtt and flow cytometry, respectively. |
2016-12-19 |
2023-08-13 |
human |
| Xin Liu, Shuda Chen, Jianfeng Tu, Wenwei Cai, Qiuran X. HSP90 inhibits apoptosis and promotes growth by regulating HIF-1α abundance in hepatocellular carcinoma. International journal of molecular medicine. vol 37. issue 3. 2016-12-19. PMID:26846697. |
flow cytometry, brdu cell proliferation assay, caspase-3/7 activity assay and mtt assay were used to detect the apoptosis and proliferation of the hcc cells. |
2016-12-19 |
2023-08-13 |
mouse |
| Yoon Lee, So-Youn An, Yoon-Jung Park, Frank H Yu, Joo-Cheol Park, Deog-Gyu Se. Cytotoxic effects of one-step self-etching adhesives on an odontoblast cell line. Scanning. vol 38. issue 1. 2016-12-16. PMID:26186405. |
mtt (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) and flow cytometric apoptosis assays were used to evaluate cell viability and the rate of apoptosis. |
2016-12-16 |
2023-08-13 |
mouse |