| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bing Liang, Wei Wei, Jianta Wang, Mingming Zhang, Ran Xu, Fei Wu, Haitao Xiao, Lei Tan. Protective effects of Semiaquilegia adoxoides n-butanol extract against hydrogen peroxide-induced oxidative stress in human lens epithelial cells. Pharmaceutical biology. vol 54. issue 9. 2017-02-13. PMID:26974044. |
the antioxidant effects of nsa were determined in terms of cell viability (mtt assay), apoptosis (annexinv/pi staining), radical scavenging capability (various enzymatic assays), loss of mitochondrial membrane potential (rhodamine 123 staining), expression of apoptotic markers including caspase-3 and caspase-9 and the change of bcl-2/bax ratio (western blot) in the hle cells. |
2017-02-13 |
2023-08-13 |
human |
| Yan-Ran Wu, Hai-Jun Qi, Dan-Fang Deng, Ying-Ying Luo, Sheng-Lan Yan. MicroRNA-21 promotes cell proliferation, migration, and resistance to apoptosis through PTEN/PI3K/AKT signaling pathway in esophageal cancer. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 9. 2017-02-13. PMID:27188433. |
western blot was used for detection of pten, p13k, and akt protein expressions, mtt method for cell proliferation, transwell assay for cell migration and invasion, and flow cytometry for cell cycle and apoptosis. |
2017-02-13 |
2023-08-13 |
human |
| Jing Wang, Yue Zhang, Qiuzhen Zhu, Yulan Liu, Hao Cheng, Yuefan Zhang, Tiejun L. Emodin protects mice against radiation-induced mortality and intestinal injury via inhibition of apoptosis and modulation of p53. Environmental toxicology and pharmacology. vol 46. 2017-02-13. PMID:27525562. |
mtt assay, flow cytometry, hoechst 33258 staining, real-time pcr, and western blotting indicated that emodin pretreatment can effectively increase human umbilical venous endothelial cells (huvecs) viability and attenuate cell apoptosis; it also inhibited the expression of p53, bax, and caspase3 in huvecs after irradiation. |
2017-02-13 |
2023-08-13 |
mouse |
| Shi-Jun Feng, Rui-Qi Chu, Jing Ma, Zheng-Xiang Wang, Guang-Jing Zhang, Xiu-Fang Yang, Zhi Song, Yun-Yi M. MicroRNA138 regulates keratin 17 protein expression to affect HaCaT cell proliferation and apoptosis by targeting hTERT in psoriasis vulgaris. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 85. 2017-02-13. PMID:27936398. |
mtt assay, flow cytometry with pi single staining and annexin v/pi double staining were performed to detect the cell proliferation activity, cell cycle and apoptosis, respectively. |
2017-02-13 |
2023-08-13 |
Not clear |
| Dan-Dan Yu, Ying Wu, Xiao-Hui Zhang, Meng-Meng Lv, Wei-Xian Chen, Xiu Chen, Su-Jin Yang, Hongyu Shen, Shan-Liang Zhong, Jin-Hai Tang, Jian-Hua Zha. Exosomes from adriamycin-resistant breast cancer cells transmit drug resistance partly by delivering miR-222. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 3. 2017-02-10. PMID:26432333. |
cell viability was assessed by mtt assay and apoptosis assay. |
2017-02-10 |
2023-08-13 |
Not clear |
| Shuo Zhang, Lei Gao, Asmitananda Thakur, Puyu Shi, Feng Liu, Jing Feng, Ting Wang, Yiqian Liang, Johnson J Liu, Mingwei Chen, Hui Re. miRNA-204 suppresses human non-small cell lung cancer by targeting ATF2. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 8. 2017-02-08. PMID:26935060. |
rna isolation, qrt-pcr, mtt, colony formation assay, cell cycle assay, cell apoptosis assay, cell migration assay, and western blot were performed. |
2017-02-08 |
2023-08-13 |
human |
| L Zhang, Z K Zhang, S Lian. Epigallocatechin-3-gallate protects retinal vascular endothelial cells from high glucose stress in vitro via the MAPK/ERK-VEGF pathway. Genetics and molecular research : GMR. vol 15. issue 2. 2017-02-08. PMID:27323164. |
the cell viability was determined by a standard mtt assay, while the cell cycle and apoptosis rate were analyzed by flow cytometry. |
2017-02-08 |
2023-08-13 |
human |
| Rong-Rong Lei, Hai-Feng Hu, Fan Bai, Ying Liu, Chun-Zhen Wu, Xiao-Xing Huang, Li-Ping Xie, You-Jia H. Anti-proliferative and apoptotic effects of S1, a tetrandrine derivative, in human gastric cancer BGC-823 cells. Chinese journal of natural medicines. vol 14. issue 7. 2017-02-08. PMID:27507203. |
the anti-proliferative activity was determined by mtt assay; the induction of cell cycle arrest and apoptosis were detected by flow cytometry. |
2017-02-08 |
2023-08-13 |
human |
| A Mohammadi, M M Yaghoobi, A GholamhoseynianNajar, B Kalantari-Khandani, H Sharifi, M Saravan. HSP90 inhibitor enhances anti-proliferative and apoptotic effects of celecoxib on HT-29 colorectal cancer cells via increasing BAX/BCL-2 ratio. Cellular and molecular biology (Noisy-le-Grand, France). vol 62. issue 12. 2017-02-08. PMID:27894402. |
based on mtt results, we showed an increase in the inhibitory effect of celecoxib when combined with 17-aag, especially at low a concentration of celecoxib. flow cytometry analysis demonstrated that apoptosis induction is probably the mechanism of additive inhibitory effects of 17-aag and celecoxib combination. |
2017-02-08 |
2023-08-13 |
Not clear |
| Zahra Goodarzi, Hoorieh Soleimanjahi, Ehsan Arefian, Esmaeil Saberfa. The effect of bovine rotavirus and its nonstructural protein 4 on ER stress-mediated apoptosis in HeLa and HT-29 cells. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 3. 2017-02-07. PMID:26427658. |
mtt, flow cytometry, and western blot were used to evaluate the cell viability, apoptosis, and expression level of c/ebp-homologous protein (chop) and activated caspase-4. |
2017-02-07 |
2023-08-13 |
cattle |
| Sadhna Aggarwal, Satya N Da. Garcinol inhibits tumour cell proliferation, angiogenesis, cell cycle progression and induces apoptosis via NF-κB inhibition in oral cancer. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 6. 2017-02-07. PMID:26662963. |
three oscc cell lines (scc-4, scc-9 and scc-25) were treated with garcinol for 48 h and its effect on growth and proliferation, clonogenic survival, cell cycle and apoptosis was studied by mtt, clonogenic assay, propidium iodide (pi) staining and annexin-v binding assay, respectively. |
2017-02-07 |
2023-08-13 |
Not clear |
| Zeshun Yu, Yingjun Wan, Yanni Liu, Jing Yang, Lei Li, Weiming Zhan. Curcumin induced apoptosis via PI3K/Akt-signalling pathways in SKOV3 cells. Pharmaceutical biology. vol 54. issue 10. 2017-02-07. PMID:26911246. |
the antiproliferative activity and the apoptosis rate were measured by mtt and flow cytometry. |
2017-02-07 |
2023-08-13 |
Not clear |
| Hyunwoo Jung, Jinhyung Bae, Sung Kwon Ko, Uy Dong Soh. Ultrasonication processed Panax ginseng berry extract induces apoptosis through an intrinsic apoptosis pathway in HepG2 cells. Archives of pharmacal research. vol 39. issue 6. 2017-02-07. PMID:27233905. |
cell growth and cellular apoptosis were evaluated by mtt assay and annexin v/pi staining, respectively. |
2017-02-07 |
2023-08-13 |
human |
| Wei Peng, Hong Fa. Long noncoding RNA CCHE1 indicates a poor prognosis of hepatocellular carcinoma and promotes carcinogenesis via activation of the ERK/MAPK pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 83. 2017-02-07. PMID:27427851. |
moreover, the effect of cche1 on proliferation was evaluated by mtt assays, and cell apoptosis was detected by flow-cytometric analysis. |
2017-02-07 |
2023-08-13 |
human |
| Siti Nur Hasyila Muhammad, Noor Fatmawati Mokhtar, Nik Soriani Yaaco. 15d-PGJ2 Induces Apoptosis of MCF-7 and MDA-MB-231 Cells via Increased Intracellular Calcium and Activation of Caspases, Independent of ERα and ERβ. Asian Pacific journal of cancer prevention : APJCP. vol 17. issue 7. 2017-02-07. PMID:27509924. |
cellular proliferation and cytotoxicity were determined using the 3(4,5dimethylthiazol2yl)2,5diphenyltetrazolium bromide (mtt) and lactate dehydrogenase (ldh) assays while apoptosis was determined by fluorescence microscopy and flow cytometry using annexin vpropidium iodide (pi) staining. |
2017-02-07 |
2023-08-13 |
human |
| Junyan Cai, Guangyu Shen, Su Liu, Qingbing Men. Downregulation of HMGA2 inhibits cellular proliferation and invasion, improves cellular apoptosis in prostate cancer. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 1. 2017-02-06. PMID:26242267. |
then, the changes in proliferation, apoptosis, invasion, and migration of pc3 cells were examined by mtt test, pi staining, annexin v-fitc staining, and transwell chamber assay. |
2017-02-06 |
2023-08-13 |
human |
| Yijun Wang, Wei Zhang, Qiongying Lv, Juan Zhang, Dingjun Zh. The critical role of quercetin in autophagy and apoptosis in HeLa cells. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 1. 2017-02-06. PMID:26260273. |
here, hela cells were subjected to quercetin treatment, and then proliferation, apoptosis, and autophagy were evaluated using mtt, flow cytometry, and mdc staining, respectively. |
2017-02-06 |
2023-08-13 |
Not clear |
| Chien-Yu Huang, Yu-Jia Chang, Sheng-Dean Luo, Batzorig Uyanga, Feng-Yen Lin, Cheng-Jeng Tai, Ming-Te Huan. Maspin mediates the gemcitabine sensitivity of hormone-independent prostate cancer. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 3. 2017-02-06. PMID:26490978. |
the cytotoxicity of gemcitabine to prostate cancer cells was assessed using 3-[4,5-dimethylthiazol-2-yl]-3,5-diphenyl tetrazolium bromide (mtt) assays, whereas flow cytometry analyses and annexin v-propidium iodide (pi) apoptosis assays were used to assess the ability of gemcitabine to induce apoptosis in maspin-kd and control cells. |
2017-02-06 |
2023-08-13 |
Not clear |
| Wei Dai, Quangen Gao, Jianping Qiu, Jianmao Yuan, Guoliang Wu, Genhai She. Quercetin induces apoptosis and enhances 5-FU therapeutic efficacy in hepatocellular carcinoma. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 5. 2017-02-06. PMID:26628295. |
the antiproliferative effects of q were measured by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt), and the apoptosis and cell cycle dynamics were assessed by flow cytometry; the expression of apoptosis-associated proteins were evaluated by western blot and immunohistochemistry staining; the tumor growth in vivo was evaluated in a xenograft mouse model. |
2017-02-06 |
2023-08-13 |
mouse |
| Z Peng, Y Zhan. Propofol inhibits proliferation and accelerates apoptosis of human gastric cancer cells by regulation of microRNA-451 and MMP-2 expression. Genetics and molecular research : GMR. vol 15. issue 2. 2017-02-06. PMID:27173190. |
the effects of propofol on proliferation and apoptosis in the sgc-7901 gastric cancer cell line were detected by an mtt assay and measurement of caspase-3 activity. |
2017-02-06 |
2023-08-13 |
human |