| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dan Yan, Zhidong Teng, Shiqi Sun, Shan Jiang, Hu Dong, Yuan Gao, Yanquan Wei, Wenwu Qin, Xiangtao Liu, Hong Yin, Huichen Gu. Foot-and-mouth disease virus-like particles as integrin-based drug delivery system achieve targeting anti-tumor efficacy. Nanomedicine : nanotechnology, biology, and medicine. vol 13. issue 3. 2017-06-19. PMID:27993721. |
the effects of fmdv-vlps-dox on cellular internalization and viability were evaluated in vitro by cell imaging, mtt assay and apoptosis, respectively. |
2017-06-19 |
2023-08-13 |
mouse |
| Richun Zhang, Hongtao Zhang, Zhen E, Qiong Ma, Shiju Yan, Enwei Zhang, Bao'an M. [CCR7 silence by siRNA inhibits proliferation, invasion and promotes apoptosis of human MG63 osteosarcoma cells]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 32. issue 12. 2017-06-13. PMID:27916085. |
after mg63 cells were transfected with ccr7-sirna, the expression of ccr7 was identified by western blotting; cell apoptosis was detected by annexinv-fitc/pi double staining combined with flow cemetery; cell proliferation was tested by mtt assay; and cell migration and invasion abilities were examined by transwell |
2017-06-13 |
2023-08-13 |
human |
| Zhiwei Ma, Yizhao Luo, Mingxing Qi. miR-143 Induces the Apoptosis of Prostate Cancer LNCap Cells by Suppressing Bcl-2 Expression. Medical science monitor : international medical journal of experimental and clinical research. vol 23. 2017-06-08. PMID:28109198. |
the proliferation and apoptosis were detected by mtt assay, flow cytometry, and caspase-3 activity assay. |
2017-06-08 |
2023-08-13 |
Not clear |
| Sheng-Jia Yu, Zi-Wen Lon. Effect of SOCS1 silencing on proliferation and apoptosis of melanoma cells: An in vivo and in vitro study. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 39. issue 5. 2017-06-08. PMID:28466787. |
the proliferation, cell cycle and apoptosis, and messenger rna expression of socs1 in mv3 and a375 cells were detected using mtt assay, flow cytometry, and quantitative real-time polymerase chain reaction, respectively. |
2017-06-08 |
2023-08-13 |
mouse |
| Xin-Ying Zhou, Jing Cao, Chao-Ming Han, Shu-Wen Li, Chen Zhang, Yin-Duan Du, Qian-Qian Zhou, Xin-Yan Zhang, Xin Che. The C8 side chain is one of the key functional group of Garcinol for its anti-cancer effects. Bioorganic chemistry. vol 71. 2017-06-06. PMID:28169002. |
the antitumor activity of garcinol and 8-me garcinol was evaluated in vitro by mtt, cell cycle and cell apoptosis assays. |
2017-06-06 |
2023-08-13 |
Not clear |
| C Pan, Y Wang, M K Qiu, S Q Wang, Y B Liu, Z W Quan, J M O. Knockdown of HMGB1 inhibits cell proliferation and induces apoptosis in hemangioma via downregulation of AKT pathway. Journal of biological regulators and homeostatic agents. vol 31. issue 1. 2017-06-01. PMID:28337869. |
cell function experiments, including mtt, cell colony formation and flow cytometry analysis were performed to evaluate the effects of hmgb1 knockdown on cell proliferation and apoptosis in ha crl-2586 eoma cells. |
2017-06-01 |
2023-08-13 |
human |
| L X Fu, Q W Lian, J D Pan, Z L Xu, T M Zhou, B Y. JAK2 tyrosine kinase inhibitor AG490 suppresses cell growth and invasion of gallbladder cancer cells via inhibition of JAK2/STAT3 signaling. Journal of biological regulators and homeostatic agents. vol 31. issue 1. 2017-06-01. PMID:28337870. |
our present study aimed to investigate the effects and associated mechanisms of jak inhibitor ag490 on cell growth, invasive potential and apoptosis in gbc cells (gbc-sd and sgc-996) indicated by mtt, cell colony formation, transwell and flow cytometry. |
2017-06-01 |
2023-08-13 |
Not clear |
| X-G Li, W-G Sui, C-Q Gao, H-C Yan, Y-L Yin, H-C Li, X-Q Wan. L-Glutamate deficiency can trigger proliferation inhibition via down regulation of the mTOR/S6K1 pathway in pig intestinal epithelial cells. Journal of animal science. vol 94. issue 4. 2017-05-31. PMID:27136013. |
cell proliferation ( = 24), cell cycle distribution ( = 6), cell apoptosis ( = 6), and expression levels of proteins of interest ( = 4) were determined by mtt assay, flow cytometry, or western blot. |
2017-05-31 |
2023-08-13 |
Not clear |
| D Bai, S Cong, L P Zh. Attenuation of Focal Adhesion Kinase Reduces Lipopolysaccharide-Induced Inflammation Injury through Inactivation of the Wnt and NF-κB Pathways in A549 Cells. Biochemistry. Biokhimiia. vol 82. issue 4. 2017-05-31. PMID:28371601. |
flow cytometry, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay, quantitative reverse transcription polymerase chain reaction, and western blot analysis were used to explore the correlation of fak expression with cell apoptosis, viability, and the inflammatory cytokine activity in a549 cells. |
2017-05-31 |
2023-08-13 |
Not clear |
| Ning Jia, Qinru Sun, Qian Su, Guomin Che. SIRT1-mediated deacetylation of PGC1α attributes to the protection of curcumin against glutamate excitotoxicity in cortical neurons. Biochemical and biophysical research communications. vol 478. issue 3. 2017-05-29. PMID:27568287. |
the mtt and tunel methods were employed to measure cell viability and apoptosis, respectively. |
2017-05-29 |
2023-08-13 |
Not clear |
| Xiaochuan Wang, Ping Cao, Jian Liu, Peng Du, Zhiqiong Wang, Wei Chen, Chang Liu, Yifei W. 5-Aminolaevulinic Acid-Based Photodynamic Therapy Restrains Pathological Hyperplasia of Fibroblasts. Medical science monitor : international medical journal of experimental and clinical research. vol 23. 2017-05-26. PMID:28052053. |
material and methods we used mtt assay, flow cytometry, and terminal-deoxynucleotidyl transferase mediated nick-end labeling (tunel) to examine the effects of ala-pdt on proliferation, cell cycle, and apoptosis of fibroblasts isolated from hyperplastic scar tissues. |
2017-05-26 |
2023-08-13 |
Not clear |
| Jinzhong Yu, Ruijie Wang, Jianshe Chen, Jinfeng Wu, Zhongqin Dang, Qinsheng Zhang, Bo L. miR-340 Inhibits Proliferation and Induces Apoptosis in Gastric Cancer Cell Line SGC-7901, Possibly via the AKT Pathway. Medical science monitor : international medical journal of experimental and clinical research. vol 23. 2017-05-26. PMID:28057912. |
after transfection, cell viability, proliferation, and apoptosis were examined by mtt, brdu, and flow cytometry assays, respectively. |
2017-05-26 |
2023-08-13 |
human |
| Jiewen Wang, Xiaodong Chen, Maoqing Ton. Knockdown of astrocyte elevated gene-1 inhibited cell growth and induced apoptosis and suppressed invasion in ovarian cancer cells. Gene. vol 616. 2017-05-26. PMID:28323000. |
to explore the role and molecular insight on aeg-1-mediated tumorigenesis in ovarian cancer, multiple approaches are performed including mtt assay, flow cytometry for apoptosis and cell cycle assay, gene transfection, real-time rt-pcr, western blotting, and transwell assay. |
2017-05-26 |
2023-08-13 |
Not clear |
| Yan Wang, Liu Tu, Yingbo Li, Di Chen, Shali Wan. Notoginsenoside R1 Protects against Neonatal Cerebral Hypoxic-Ischemic Injury through Estrogen Receptor-Dependent Activation of Endoplasmic Reticulum Stress Pathways. The Journal of pharmacology and experimental therapeutics. vol 357. issue 3. 2017-05-23. PMID:26892460. |
after hie conditions in vitro and in vivo, we administered ngr1 or the estrogen receptor inhibitor ici-182780 and measured cell apoptosis, brain injury by mtt assay, ttc stain, and so forth. |
2017-05-23 |
2023-08-13 |
rat |
| Yongjie Wang, Jinghong Rong, Jiaozhen Zhang, Yu Liu, Xuelian Meng, Hejian Guo, Hongsheng Liu, Lijiang Che. Morphology, in vivo distribution and antitumor activity of bexarotene nanocrystals in lung cancer. Drug development and industrial pharmacy. vol 43. issue 1. 2017-05-23. PMID:27588517. |
in addition, mtt assay, flow cytometry analysis, observation of morphological changes and apoptotic body demonstrated that bexarotene nanocrystals could significantly enhance the in vitro cytotoxicity and induced g1 cycle arrest and apoptosis against a549 cells. |
2017-05-23 |
2023-08-13 |
mouse |
| Jian Ji, Pei Zhu, Chao Sun, Jiadi Sun, Lu An, Yinzhi Zhang, Xiulan Su. Pathway of 3-MCPD-induced apoptosis in human embryonic kidney cells. The Journal of toxicological sciences. vol 42. issue 1. 2017-05-23. PMID:28070108. |
cell viability and apoptosis were assessed in response to exposure to 3-mcpd using the mtt assay and high-content screening (hcs). |
2017-05-23 |
2023-08-13 |
human |
| Li Qiao, Chengshan Xu, Qiang Li, Zhusong Mei, Xinji Li, Hong Cai, Wei Li. Photodynamic therapy activated STAT3 associated pathways: Targeting intrinsic apoptotic pathways to increase PDT efficacy in human squamous carcinoma cells. Photodiagnosis and photodynamic therapy. vol 14. 2017-05-17. PMID:26607555. |
apoptosis and cell viability after pdt were evaluated using annexin v-fitc apoptosis detection kit and mtt assay. |
2017-05-17 |
2023-08-13 |
human |
| Junjia Zhang, Jichun Yu, Rong Xie, Wanzhi Chen, Yunxia L. Combinatorial anticancer effects of curcumin and sorafenib towards thyroid cancer cells via PI3K/Akt and ERK pathways. Natural product research. vol 30. issue 16. 2017-05-16. PMID:26299635. |
the objective of this study was to examine the in vitro combinatorial anticancer effects of curcumin and sorafenib towards thyroid cancer cells ftc133 using a mtt cytotoxicity assay, and to test whether the mechanism involves induction of apoptosis. |
2017-05-16 |
2023-08-13 |
Not clear |
| Ning Yang, Yuying Zhao, Zhipeng Wang, Yu Liu, Yanqiao Zhan. Scutellarin suppresses growth and causes apoptosis of human colorectal cancer cells by regulating the p53 pathway. Molecular medicine reports. vol 15. issue 2. 2017-05-16. PMID:28035355. |
human colon cancer cells were exposed to different concentrations of scutellarin, and cellular growth and apoptosis were evaluated by mtt assay, terminal deoxynucleotidyl transferase‑mediated dutp nick end labeling (tunel) staining, western blot analysis and other assays. |
2017-05-16 |
2023-08-13 |
human |
| Meng-Di Li, Wan-Peng Cheng, Min-Xia Shi, Tang-Dong Ge, Xiao-Lin Zheng, Dong-Yuan Wu, Xiao-Yan Hu, Jin-Cheng Luo, Feng-Lan Li, Hui L. Role of tRNA selenocysteine 1 associated protein 1 in the proliferation and apoptosis of cardiomyocyte‑like H9c2 cells. Molecular medicine reports. vol 15. issue 2. 2017-05-16. PMID:28101579. |
using mtt, proliferating cell nuclear antigen, annexin v and caspase‑3 activity assays, it was demonstrated that reducing trnau1ap expression levels inhibited the proliferation of h9c2 cells and induced apoptosis. |
2017-05-16 |
2023-08-13 |
Not clear |