| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yonggang Lyu, Xin Xu, Jun Yun, Jun Yi, Xin Li, Xianghua Liu, Rui Ling, Ling Wang, Jing Fa. [TNF-α regulates the proliferation of human breast cancer cells via regulation of ceramide content]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 33. issue 10. 2018-05-15. PMID:29169412. |
mtt assay was used to determine the proliferation of the cancer cells and western blotting was performed to measure the protein expressions of acid sphingomyelinase (asm), sphk1 and apoptosis or proliferation relevant factors including bcl2, bax and proliferating cell nuclear antigen (pcna). |
2018-05-15 |
2023-08-13 |
human |
| Ying Wu, Zhe Wang, Jing Kong, Jian Zhang, Rui Lin. [Aspirin inhibits the proliferation of breast cancer cells via inducing apoptosis and autophagy]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 33. issue 10. 2018-05-15. PMID:29169419. |
methods mtt assay was performed to detect the effect of aspirin on cell proliferation of cancer cells; flow cytometry was performed to assess the effect of aspirin on cell apoptosis; western blotting was used to determine the protein expressions of apoptosis-related proteins bcl2, cleaved caspase-3 (c-caspase-3), cleaved parp (c-parp) and autophagy-related gene 3 (atg3), lc3a, lc3b. |
2018-05-15 |
2023-08-13 |
human |
| Jun Lei, Ju-Hua Xiao, Shou-Hua Zhang, Zhi-Qiang Liu, Kai Huang, Zhi-Peng Luo, Xin-Lan Xiao, Zheng-Dong Hon. Non-coding RNA 886 promotes renal cell carcinoma growth and metastasis through the Janus kinase 2/signal transducer and activator of transcription 3 signaling pathway. Molecular medicine reports. vol 16. issue 4. 2018-05-14. PMID:28765891. |
cell proliferation, cell apoptosis rate and cell invasion ability were determined by mtt, flow cytometry and transwell‑matrigel invasion assays. |
2018-05-14 |
2023-08-13 |
human |
| Gang Li, Ziming Wang, Tie Chong, Jie Yang, Hongliang Li, Haiwen Che. Curcumin enhances the radiosensitivity of renal cancer cells by suppressing NF-κB signaling pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 94. 2018-05-14. PMID:28810535. |
cell viability, dna repair, cell cycle, and apoptosis, were evaluated by mtt, immunofluoresence staining and flow cytometry. |
2018-05-14 |
2023-08-13 |
mouse |
| Yanli Wang, Yanyan Fan, Chunhua Zheng, Xiaomeng Zhan. Knockdown of AQP1 inhibits growth and invasion of human ovarian cancer cells. Molecular medicine reports. vol 16. issue 4. 2018-05-11. PMID:28849036. |
in addition, a short interfering (si)rna targeting aqp1 was established, and transfected into the skov3 ovarian cancer cell line, to investigate the effects on cell viability, apoptosis, migration and invasion in the ovarian cancer cells using an mtt assay, flow cytometry, wound healing and transwell invasion chamber assays, respectively. |
2018-05-11 |
2023-08-13 |
human |
| Kun Yu, Yi Ren, Xiwen Zhang, Taiping Qiao, Zhiguo Liu, Jianhua Shi, Yingnan Wan. shRNA‑mediated NP knockdown inhibits the apoptosis of cardiomyocytes induced by H1N1pdm2009 influenza virus. Molecular medicine reports. vol 16. issue 2. 2018-05-10. PMID:28627657. |
an mtt assay and flow cytometric analysis were performed to determine the virus‑associated alterations in cellular viability and apoptosis, respectively. |
2018-05-10 |
2023-08-13 |
Not clear |
| Thomas Gehrke, Agmal Scherzad, Stephan Hackenberg, Pascal Ickrath, Philipp Schendzielorz, Rudolf Hagen, Norbert Kleinsasse. Additive antitumor effects of celecoxib and simvastatin on head and neck squamous cell carcinoma in vitro. International journal of oncology. vol 51. issue 3. 2018-05-10. PMID:28713941. |
analysis of tumor viability, proliferation, apoptosis, cell cycle changes and secretion of interleukin-6 (il-6) and interleukin-8 (il-8) was conducted via mtt assay, annexin v-propidium iodide test, cell cycle analysis, colony assay and enzyme-linked immunosorbent assay (elisa). |
2018-05-10 |
2023-08-13 |
Not clear |
| Dong Zhao, Jinhua Jia, Hong Sha. miR-30e targets GLIPR-2 to modulate diabetic nephropathy: Journal of molecular endocrinology. vol 59. issue 2. 2018-05-10. PMID:28733476. |
mtt and flow cytometry were utilized to measure the proliferation and apoptosis of rtecs, while qrt-pcr and western blot to detect the expression of glipr-2- and emt-related factors. |
2018-05-10 |
2023-08-13 |
mouse |
| Liu Yang, Fei Peng, Jian Qin, Henghua Zhou, Bing Wan. Downregulation of microRNA-196a inhibits human liver cancer cell proliferation and invasion by targeting FOXO1. Oncology reports. vol 38. issue 4. 2018-05-10. PMID:28791406. |
mtt and colony formation assays indicated that downregulation of mir-196a inhibited liver cancer cell proliferation which was due to the induction of cell apoptosis. |
2018-05-10 |
2023-08-13 |
mouse |
| Qing Du, Jia Liu, Xuezhi Zhang, Xin Zhang, He Zhu, Ming Wei, Shilei Wan. Propofol inhibits proliferation, migration, and invasion but promotes apoptosis by regulation of Sox4 in endometrial cancer cells. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 51. issue 4. 2018-05-08. PMID:29490000. |
colony number, cell viability, cell cycle, apoptosis, migration, and invasion were analyzed by colony formation, mtt, flow cytometry, and transwell assays. |
2018-05-08 |
2023-08-13 |
Not clear |
| M Lang, Z Zhou, L Shi, J Niu, S Xu, W Lin, Z Chen, Y Wan. Influence of zoledronic acid on proliferation, migration, and apoptosis of vascular endothelial cells. The British journal of oral & maxillofacial surgery. vol 54. issue 8. 2018-05-07. PMID:27344431. |
endothelial cell proliferation, migration, and apoptosis were examined with mtt assays, scratch tests, and flow cytometry in the presence of zoledronic acid in different concentrations. |
2018-05-07 |
2023-08-13 |
Not clear |
| Shengguang Chen, Xianzheng Wu, Jiawen Hu, Guoxing Dai, Aihong Rong, Gang Gu. PM2.5 exposure decreases viability, migration and angiogenesis in human umbilical vein endothelial cells and human microvascular endothelial cells. Molecular medicine reports. vol 16. issue 3. 2018-04-30. PMID:28677750. |
cell viability and cell apoptosis were determined by mtt assay and flow cytometry analysis. |
2018-04-30 |
2023-08-13 |
human |
| Liangzhi Du, Siwei Ma, Xi Wen, Juan Chai, Dangxia Zho. Oral squamous cell carcinoma cells are resistant to doxorubicin through upregulation of miR‑221. Molecular medicine reports. vol 16. issue 3. 2018-04-30. PMID:28677788. |
in addition, the scc4 and scc9 oscc cell lines were transfected with anti‑mir‑221 oligonucleotides and cell viability and apoptosis following doxorubicin treatment were evaluated using an mtt assay and annexin v‑fluorescein isothiocyanate/hoechst double staining, respectively. |
2018-04-30 |
2023-08-13 |
Not clear |
| Jun Shi, Huiping Deng, Min Zhan. Curcumin pretreatment protects against PM2.5‑induced oxidized low‑density lipoprotein‑mediated oxidative stress and inflammation in human microvascular endothelial cells. Molecular medicine reports. vol 16. issue 3. 2018-04-30. PMID:28713935. |
the hmec‑1 viability and apoptosis were detected by mtt and annexin v‑fluorescein isothiocyanate/propidium iodide assays. |
2018-04-30 |
2023-08-13 |
human |
| Nadiar Mussin, Seung Cheol Oh, Kwang Woong Lee, Min Young Park, Sooin Seo, Nam Joon Yi, Hyeyoung Kim, Kyung Chul Yoon, Sung Woo Ahn, Hyo Sin Kim, Suk Kyun Hong, Dong Kyu Oh, Kyung Suk Su. Sirolimus and Metformin Synergistically Inhibits Colon Cancer In Vitro and In Vivo. Journal of Korean medical science. vol 32. issue 9. 2018-04-30. PMID:28776332. |
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay was performed and western blot analyses were performed for mtor pathway proteins, apoptosis proteins, and epithelial-mesenchymal-transition (emt) proteins. |
2018-04-30 |
2023-08-13 |
mouse |
| Jian Wang, Ke Liu, Xiao-Feng Wang, Dian-Jun Su. Juglone reduces growth and migration of U251 glioblastoma cells and disrupts angiogenesis. Oncology reports. vol 38. issue 4. 2018-04-30. PMID:28791366. |
cell survival, apoptosis, migration, angiogenesis and molecular targets were identified with multiple detection techniques including the mtt cell proliferation assay, dual acridine orange/ethidium bromide staining, electron microscopy, transwell migration assay, chick chorioallantoic membrane assay, quantitative real-time polymerase chain reaction and immunoblotting. |
2018-04-30 |
2023-08-13 |
human |
| Yuan Shen, Xiaoyu Wang, Jianping Xu, Lin L. SerpinE2, a poor biomarker of endometrial cancer, promotes the proliferation and mobility of EC cells. Cancer biomarkers : section A of Disease markers. vol 19. issue 3. 2018-04-26. PMID:28453461. |
meanwhile, we knocked down serpine2 by sirna in the htb-111 and ishikawa ec cell lines and analyzed the viability and mobility change using an mtt assay, an annexin v/pi apoptosis assay, a wound scratch test and a transwell assay. |
2018-04-26 |
2023-08-13 |
Not clear |
| Kanawut Kotawong, Wanna Chaijaroenkul, Phunuch Muhamad, Kesara Na-Bangchan. Cytotoxic activities and effects of atractylodin and β-eudesmol on the cell cycle arrest and apoptosis on cholangiocarcinoma cell line. Journal of pharmacological sciences. vol 136. issue 2. 2018-04-24. PMID:29525035. |
effects of the compounds on cell cytotoxicity, cell cycle arrest, and cell apoptosis were analyzed using mtt assay, bd cycletest™ plus dna kit, and fitc annexin v apoptosis detection kit i, respectively. |
2018-04-24 |
2023-08-13 |
Not clear |
| Bin Xu, Hehuan Xia, Junming Cao, Zhihong Wang, Yipeng Yang, Yongsheng Li. MicroRNA-21 Inhibits the Apoptosis of Osteosarcoma Cell Line SAOS-2 via Targeting Caspase 8. Oncology research. vol 25. issue 7. 2018-04-23. PMID:28109080. |
human osteosarcoma cell line saos-2 was transfected with either mir-21 mimic or mir-21 inhibitor, and then cell viability, survival, and apoptosis were measured by mtt, colony formation assay, and flow cytometry. |
2018-04-23 |
2023-08-13 |
human |
| Chaoliang Wang, Jianxiang Zhang, Qi Li, Tianbiao Zhang, Zishi Deng, Jing Lian, Donghui Jia, Rui Li, Tao Zheng, Xiaoju Ding, Fan Yang, Chao Ma, Rui Wang, Weixing Zhang, Jian Guo We. Low concentration of BPA induces mice spermatocytes apoptosis via GPR30. Oncotarget. vol 8. issue 30. 2018-04-23. PMID:28446726. |
the results of mtt assay, comet assay and flow cytometry indicated that the activation of gpr30 induced by bpa inhibited the cell growth and induced cell apoptosis and ici, gpr30 sirna, egfr inhibitor (ag), and mapk (pd) inhibitor could partially reverse this effect. |
2018-04-23 |
2023-08-13 |
mouse |