| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qing-Jian Ou, Xiao-Jun Wu, Jian-Hong Peng, Rong-Xin Zhang, Zhen-Hai Lu, Wu Jiang, Lin Zhang, Zhi-Zhong Pan, De-Sen Wan, Yu-Jing Fan. Endocrine therapy inhibits proliferation and migration, promotes apoptosis and suppresses survivin protein expression in colorectal cancer cells. Molecular medicine reports. vol 16. issue 5. 2018-07-23. PMID:28849238. |
cell viability was assessed using an mtt assay, while apoptosis was detected using flow cytometry analysis. |
2018-07-23 |
2023-08-13 |
human |
| Jike Song, Dadong Guo, Hongsheng B. Chlorogenic acid attenuates hydrogen peroxide‑induced oxidative stress in lens epithelial cells. International journal of molecular medicine. vol 41. issue 2. 2018-07-23. PMID:29207051. |
using mtt assay, reverse transcription‑quantitative polymerase chain reaction (rt‑qpcr) and elisa techniques, cell viability, and protein/mrna levels of bcl2 apoptosis regulator (bcl‑2) and bcl2 associated x apoptosis regulator (bax) were investigated. |
2018-07-23 |
2023-08-13 |
human |
| Wenjing Zhang, Jian Zheng, Juan Meng, Lingling Neng, Xiaohua Chen, Zhaobing Qi. Macrophage migration inhibitory factor knockdown inhibit viability and induce apoptosis of PVM/Ms. Molecular medicine reports. vol 16. issue 6. 2018-07-20. PMID:28990052. |
cell viability was determined using an mtt assay and cell apoptosis was determined using flow cytometry analysis. |
2018-07-20 |
2023-08-13 |
mouse |
| Weihua Li, Min Lu, Yanhong Zhang, Danqin Xia, Zebin Chen, Linhua Wang, Nina Yin, Zhigang Wan. Puerarin attenuates the daunorubicin-induced apoptosis of H9c2 cells by activating the PI3K/Akt signaling pathway via the inhibition of Ca2+ influx. International journal of molecular medicine. vol 40. issue 6. 2018-07-20. PMID:29039532. |
mtt assay and flow cytometry were performed to evaluate cell cytotoxicity and apoptosis, respectively. |
2018-07-20 |
2023-08-13 |
Not clear |
| Boduan Xiao, Yun Qin, Chang Ying, Buyun Ma, Binrong Wang, Fei Long, Ruwei Wang, Ling Fang, Yigang Wan. Combination of oncolytic adenovirus and luteolin exerts synergistic antitumor effects in colorectal cancer cells and a mouse model. Molecular medicine reports. vol 16. issue 6. 2018-07-20. PMID:29039580. |
the cytotoxicity and tumor cell apoptosis mediated by combination treatment in crc cells were detected via an mtt assay, hoechst staining and western blotting, respectively. |
2018-07-20 |
2023-08-13 |
mouse |
| Yao-Dong Chen, Yu Zhang, Tian-Xiu Dong, Yu-Tong Xu, Wei Zhang, Ting-Ting An, Peng-Fei Liu, Xiu-Hua Yan. Hyperthermia with different temperatures inhibits proliferation and promotes apoptosis through the EGFR/STAT3 pathway in C6 rat glioma cells. Molecular medicine reports. vol 16. issue 6. 2018-07-20. PMID:29039593. |
mtt assay and annexin v‑fluorescein isothiocyanate/propidium iodide staining were used for investigating the proliferation and apoptosis of c6 cells, respectively. |
2018-07-20 |
2023-08-13 |
human |
| Zhenkai Lou, Xingguo Li, Xueling Zhao, Kaili Du, Xing Li, Bing Wan. Resveratrol attenuates hydrogen peroxide‑induced apoptosis, reactive oxygen species generation, and PSGL‑1 and VWF activation in human umbilical vein endothelial cells, potentially via MAPK signalling pathways. Molecular medicine reports. vol 17. issue 2. 2018-07-18. PMID:29207192. |
huvecs were pretreated with resveratrol for 2 h and incubated with hydrogen peroxide (h2o2) for 24 h prior to the evaluation of cell viability, ros generation, apoptosis and thrombosis‑associated marker expression by performing mtt assays, 2',7'‑dichlorofluorescin diacetate reagent, flow cytometry, and reverse transcription‑quantitative polymerase chain reaction (rt‑qpcr) and western blot analysis, respectively. |
2018-07-18 |
2023-08-13 |
human |
| Jixian Liu, Xinhuang Yao, Da Wu, Yiwang Ye, Qiang Wu, Suyue Liu, Hao W. Effect of TW37 on the growth of H1975 EGFR‑TKI‑resistant lung cancer cells and its underlying mechanisms. Molecular medicine reports. vol 17. issue 2. 2018-07-18. PMID:29207200. |
mtt, flow cytometry, migration and transwell invasion assays were preformed to investigate the proliferation, apoptosis, migration and invasion of h1975/egfr‑tki cells, respectively. |
2018-07-18 |
2023-08-13 |
Not clear |
| Xiaodi Li, Yuhao Jin, Zekun Mu, Wei Chen, Songshan Jian. MicroRNA‑146a‑5p enhances cisplatin‑induced apoptosis in ovarian cancer cells by targeting multiple anti‑apoptotic genes. International journal of oncology. vol 51. issue 1. 2018-07-17. PMID:28560455. |
in this study, the role of mir‑146a‑5p in cisplatin‑induced apoptosis of ovarian cancer cells was assessed by dapi staining, mtt assays, and monitoring expression of xiap, bcl2l2, birc2 and birc5 through a dual‑luciferase assay. |
2018-07-17 |
2023-08-13 |
Not clear |
| Bei Zhang, Yong Liu, Yajun Li, Xiao Zhe, Shijun Zhang, Lei Zhan. Neuroglobin promotes the proliferation and suppresses the apoptosis of glioma cells by activating the PI3K/AKT pathway. Molecular medicine reports. vol 17. issue 2. 2018-07-17. PMID:29207186. |
furthermore, mk2206 treatment reduced the proliferation and induced the apoptosis of ngb‑overexpressing u87 cells, as indicated by the results of mtt, colony formation and flow cytometry assays. |
2018-07-17 |
2023-08-13 |
Not clear |
| Shuping You, Yun Guan, Weihong L. Epithelial‑mesenchymal transition in colorectal carcinoma cells is mediated by DEK/IMP3. Molecular medicine reports. vol 17. issue 1. 2018-07-16. PMID:29115492. |
subsequently, mtt assays and flow cytometry were utilized to measure cell viability, and apoptosis, respectively. |
2018-07-16 |
2023-08-13 |
Not clear |
| Lixiang Ding, Genai Zhang, Yu Hou, Jiao Chen, Yukun Yi. Elemene inhibits osteosarcoma growth by suppressing the renin‑angiotensin system signaling pathway. Molecular medicine reports. vol 17. issue 1. 2018-07-16. PMID:29115494. |
mtt, migration, transwell invasion and terminal deoxynucleotidyltransferase‑mediated deoxy‑utp‑fluorescein nick end‑labeling assays were performed to evaluate cell viability, migration, invasion and apoptosis, respectively. |
2018-07-16 |
2023-08-13 |
mouse |
| Guang-Zhou Zhou, Yan-Yan Shi, Liu-Su Cui, A-Fang Li, Qing-Qing Wang, Min Li. Oxymatrine induces A549 human non‑small lung cancer cell apoptosis via extrinsic and intrinsic pathways. Molecular medicine reports. vol 17. issue 1. 2018-07-16. PMID:29115629. |
detection of morphological alterations, mtt analysis, hoechst/propidium iodide dual staining and terminal deoxynucleotidyl transferase dutp nick end labeling assays verified that oxymatrine induced a549 cell apoptosis. |
2018-07-16 |
2023-08-13 |
human |
| Houri Edalat, Zahra Hajebrahimi, Vahid Pirhajati, Mahmoud Tavallaei, Mansoureh Movahedin, Seyed Javad Mowl. Exogenous Expression of Nt-3 and TrkC Genes in Bone Marrow Stromal Cells Elevated the Survival Rate of the Cells in the Course of Neural Differentiation. Cellular and molecular neurobiology. vol 37. issue 7. 2018-07-13. PMID:27891557. |
cell viability was evaluated by mtt assay, while apoptosis rate was assessed by flow cytometry after pi and annexin v staining. |
2018-07-13 |
2023-08-13 |
Not clear |
| Hailian Wang, Wei Ge, Wen Jiang, Dong Li, Xiuli J. SRPK1‑siRNA suppresses K562 cell growth and induces apoptosis via the PARP‑caspase3 pathway. Molecular medicine reports. vol 17. issue 1. 2018-07-12. PMID:29138847. |
k562 cell proliferation and apoptosis were analyzed using mtt and flow cytometry respectively. |
2018-07-12 |
2023-08-13 |
human |
| Ming-Zhen Wang, Cheng-Zhi Qiu, Wai-Shi Yu, Yan-Ta Guo, Chun-Xiao Wang, Zhi-Xiong Che. GOLPH3 expression promotes the resistance of HT29 cells to 5‑fluorouracil by activating multiple signaling pathways. Molecular medicine reports. vol 17. issue 1. 2018-07-09. PMID:29115442. |
following confirmation of the effective silencing of the golph3 gene, proliferation and apoptosis of colonic cancer cells were detected by mtt assay, colony formation assay and flow cytometry, and then the mechanism of golph3‑induced resistance to 5‑fu chemotherapy in colonic cancer cells was investigated by western blotting. |
2018-07-09 |
2023-08-13 |
Not clear |
| Bo Cao, Shuwang Yang, Wuwei Li, Hong Chen, Yaze Chen, Yongfeng Liu, Bin Li. GMZ-1 is a podophyllotoxin derivative that suppresses growth and induces apoptosis in adriamycin-resistant K562/A02 cells through modulation of MDR1 expression. Molecular medicine reports. vol 17. issue 1. 2018-07-09. PMID:29115592. |
cell viability and apoptosis were measured by mtt assay and flow cytometry/giemsa staining, respectively. |
2018-07-09 |
2023-08-13 |
human |
| Rongmu Xia, Xin Sheng, Xianlin Xu, Chunbo Yu, Hongling L. Hesperidin induces apoptosis and G0/G1 arrest in human non-small cell lung cancer A549 cells. International journal of molecular medicine. vol 41. issue 1. 2018-07-09. PMID:29138795. |
initially, mtt and flow cytometric assays were performed to evaluate the effects of hesperidin on the viability and apoptosis of a549 cells and human normal lung epithelial beas-2b cells. |
2018-07-09 |
2023-08-13 |
human |
| Chun-Fei Wang, Liang Ma, Liang Feng, Mei-Rong Yin, Jun-Fei Gu, Xiao-Bin Ji. [Evaluation of nephrotoxicity induced by total terpenoids from Alismatis Rhizoma on HK-2 cells in vitro and its induction of apoptosis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 41. issue 3. 2018-07-05. PMID:28868869. |
to evaluate the nephrotoxicity of total terpenoids from alismatis rhizoma on human kidney proximal tubular cells (hk-2), explore the iraction in inducing apoptosis of hk-2 cells, and provide reference for the research of controversial nephrotoxicity of total terpenoids from alismatis rhizoma, hk-2 cells were used and cells viability was measured by mtt colorimetric method. |
2018-07-05 |
2023-08-13 |
human |
| Wei Jing, Na Song, Yunpeng Liu, Xiujuan Qu, Kezuo Hou, Xianghong Yang, Xiaofang Ch. DNA methyltransferase 3a modulates chemosensitivity to gemcitabine and oxaliplatin via CHK1 and AKT in p53‑deficient pancreatic cancer cells. Molecular medicine reports. vol 17. issue 1. 2018-07-05. PMID:29115606. |
in the present study, the effect and mechanisms of dnmt3a on gem and oxa chemosensitivity in p53‑deficient pdac cells were investigated using mtt assay, cell cycle analysis, apoptosis analysis and western blotting. |
2018-07-05 |
2023-08-13 |
Not clear |