| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Longtai You, Xiaoxv Dong, Xingbin Yin, Chunjing Yang, Xin Leng, Wenping Wang, Jian N. Rhein Induces Cell Death in HepaRG Cells through Cell Cycle Arrest and Apoptotic Pathway. International journal of molecular sciences. vol 19. issue 4. 2018-09-10. PMID:29614833. |
our results demonstrate, by 3-(4,5-dimethyl thiazol-2-yl-)-2,5-diphenyl tetrazolium bromide (mtt) and annexin v-fluoresce isothiocyanate (fitc)/propidium iodide (pi) double-staining assays, that rhein significantly inhibited cell viability and induced apoptosis in heparg cells. |
2018-09-10 |
2023-08-13 |
rat |
| Dong Guo, Yanli Wang, Kewei Ren, Xinwei Ha. Knockdown of LncRNA PVT1 inhibits tumorigenesis in non-small-cell lung cancer by regulating miR-497 expression. Experimental cell research. vol 362. issue 1. 2018-09-07. PMID:29133127. |
cell viability, invasion and apoptosis were detected by mtt assay, cell invasion assay and flow cytometry analysis, respectively. |
2018-09-07 |
2023-08-13 |
mouse |
| Yan Chen, Yu Zheng, Zhihong Zhou, Jinjun Wan. Baicalein alleviates tubular-interstitial nephritis in vivo and in vitro by down-regulating NF-κB and MAPK pathways. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 51. issue 10. 2018-09-07. PMID:30088539. |
viability and apoptosis of rptecs were measured using mtt assay and guava nexin assay, respectively. |
2018-09-07 |
2023-08-13 |
Not clear |
| Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Yuan Zhang, Zhi-Kun Liu, Heng Song, Shu-Chai Zh. BMI-1 suppression increases the radiosensitivity of oesophageal carcinoma via the PI3K/Akt signaling pathway. Oncology reports. vol 39. issue 2. 2018-09-05. PMID:29207170. |
flow cytometry and mtt assays were used to determine cell cycle progression, apoptosis and cell viability. |
2018-09-05 |
2023-08-13 |
Not clear |
| Kaishun Shi, Qingjing Ru, Chenyi Zhang, Jie Huan. Cyclin Y Modulates the Proliferation, Invasion, and Metastasis of Hepatocellular Carcinoma Cells. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2018-09-03. PMID:29557391. |
human hcc cell lines, sk-hep1, hepg2, hep3b, huh7 and l02 were studied using the mtt cell proliferation assay, cell apoptosis, transwell and wound healing assays. |
2018-09-03 |
2023-08-13 |
mouse |
| Juan Mateo Anchordoquy, Juan Patricio Anchordoquy, Noelia Nikoloff, Ana M Pascua, Cecilia C Furnu. High copper concentrations produce genotoxicity and cytotoxicity in bovine cumulus cells. Environmental science and pollution research international. vol 24. issue 24. 2018-08-30. PMID:28699012. |
we evaluated the effect of 0, 120, 240, and 360 μg/dl cu added to in vitro maturation (ivm) medium on cc viability assessed by the trypan blue (tb)-fluorescein diacetate (fda) and 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2h-tetrazolium bromide (mtt) assays, apoptosis, and dna damage. |
2018-08-30 |
2023-08-13 |
cattle |
| Xian-Qun Chu, Jing Wang, Guang-Xiang Chen, Guan-Qi Zhang, De-Yong Zhang, Yong-Yan Ca. Overexpression of microRNA-495 improves the intestinal mucosal barrier function by targeting STAT3 via inhibition of the JAK/STAT3 signaling pathway in a mouse model of ulcerative colitis. Pathology, research and practice. vol 214. issue 1. 2018-08-30. PMID:29129493. |
mtt was used for testing cell proliferation, flow cytometry for cell cycle and apoptosis. |
2018-08-30 |
2023-08-13 |
mouse |
| Lei Zhang, Wen Liu, Qun Wang, Qinpei Li, Huijuan Wang, Jun Wang, Tieshan Teng, Mingliang Chen, Ailing Ji, Yanzhang L. New Drug Candidate Targeting the 4A1 Orphan Nuclear Receptor for Medullary Thyroid Cancer Therapy. Molecules (Basel, Switzerland). vol 23. issue 3. 2018-08-30. PMID:29498706. |
mtt [3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-h-tetrazolium bromide] and apoptosis assays demonstrated that imca resulted in significant thyroid cancer cell death. |
2018-08-30 |
2023-08-13 |
Not clear |
| Pan-Pan Kang, Shu-Tong Yao, Tian-Tian Guo, Zhi-Chao Wang, Hua Tian, Peng Jiao, Jian Zhou, Shu-Cun Qi. [Activating transcription factor 6-C/EBP homologous protein pathway mediates advanced glycated albumin-induced macrophage apoptosis]. Sheng li xue bao : [Acta physiologica Sinica]. vol 69. issue 6. 2018-08-29. PMID:29270592. |
cell viability and apoptosis were determined by mtt method and annexin v-fitc/propidium iodide apoptosis detection kit, respectively. |
2018-08-29 |
2023-08-13 |
Not clear |
| Wei Shi, Xiaoling Wang, Lihong Ruan, Jiamei Fu, Fang Liu, Jinfeng Q. MiR-200a promotes epithelial-mesenchymal transition of endometrial cancer cells by negatively regulating FOXA2 expression. Die Pharmazie. vol 72. issue 11. 2018-08-29. PMID:29442045. |
mtt assay measured cell proliferation, apoptosis assay measured apoptosis, transwell invasion assay measured cell invasion, and western blot measured the protein expression of foxa2, e-cadherin, and vimentin. |
2018-08-29 |
2023-08-13 |
Not clear |
| Yan Feng, Li-Li Zu, Lei Zhan. MicroRNA-26b inhibits the tumor growth of human liver cancer through the PI3K/Akt and NF-κB/MMP-9/VEGF pathways. Oncology reports. vol 39. issue 5. 2018-08-29. PMID:29498407. |
forced upregulation of microrna-26b had anticancer effects, inhibited cell proliferation, induced apoptosis and promoted bax and caspase-3/-9 protein expression in a liver cancer cell line as determined by mtt assay, flow cytometry and western blot analysis. |
2018-08-29 |
2023-08-13 |
human |
| Shinwan Kany, Mathias Woschek, Niels Kneip, Ramona Sturm, Miriam Kalbitz, Marc Hanschen, Borna Relj. Simvastatin exerts anticancer effects in osteosarcoma cell lines via geranylgeranylation and c-Jun activation. International journal of oncology. vol 52. issue 4. 2018-08-28. PMID:29532878. |
tumour growth using mtt assay, apoptosis, cell cycle and signalling cascades involved in simvastatin-induced manipulation were analysed. |
2018-08-28 |
2023-08-13 |
human |
| Dan Jiao, Man Wu, Lei Ji, Feng Liu, Yingying Li. MicroRNA-186 Suppresses Cell Proliferation and Metastasis Through Targeting Sentrin-Specific Protease 1 in Renal Cell Carcinoma. Oncology research. vol 26. issue 2. 2018-08-27. PMID:28550686. |
overexpression of mir-186 significantly inhibited cell growth, colony formation, and cell invasion; caused cell cycle arrest at the g0/g1 phase; and induced cell apoptosis as detected by mtt, colony formation, transwell assay, and flow cytometry assays in rcc cells. |
2018-08-27 |
2023-08-13 |
Not clear |
| Lu Lu, Yawei Du, Muhammad Ismail, Longbing Ling, Chen Yao, Zhenglin Fu, Xinsong L. Liposomes assembled from dimeric retinoic acid phospholipid with improved pharmacokinetic properties. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. vol 112. 2018-08-27. PMID:29162478. |
furthermore, cellular uptake, mtt and cell apoptosis analysis demonstrated that the liposomes could be successfully internalized into tumor cells to induce apoptosis of mcf-7 and hl-60 cells. |
2018-08-27 |
2023-08-13 |
Not clear |
| Haogang Zhang, Yaguang Zong, Gongcai Qiu, Ruichun Jia, Xunzheng Xu, Fujing Wang, Dequan W. Silencing Lin28 promotes apoptosis in colorectal cancer cells by upregulating let‑7c targeting of antiapoptotic BCL2L1. Molecular medicine reports. vol 17. issue 4. 2018-08-27. PMID:29393430. |
an mtt assay was conducted to assess the cell viability of hct116 and ht29 crc cells, and caspase‑3 activity was analyzed to measure the apoptosis of crc cells. |
2018-08-27 |
2023-08-13 |
Not clear |
| Yanhua Huang, Ziyi Fu, Wei Dong, Zhenming Zhang, Jinquan Mu, Junfeng Zhan. Serum starvation-induces down-regulation of Bcl-2/Bax confers apoptosis in tongue coating-related cells in vitro. Molecular medicine reports. vol 17. issue 4. 2018-08-27. PMID:29393442. |
cellular proliferation and apoptosis were observed by using 3‑[4,5‑dimethyl‑2‑thiazolyl]‑2,5‑diphenyl‑2‑h‑tetrazolium bromide (mtt) assay, flow cytometry, hoechst staining, scanning electron microscope (sem), transmission electron microscope (tem), and by measuring the expression ratio of b‑cell lymphoma 2 apoptosis regulator (bcl‑2)/bcl‑2 associated protein x apoptosis regulator (bax) mrna and protein by reverse transcription‑quantitative polymerase chain reaction (rt‑qpcr) and western blotting, respectively. |
2018-08-27 |
2023-08-13 |
Not clear |
| Yanhua Huang, Ziyi Fu, Wei Dong, Zhenming Zhang, Jinquan Mu, Junfeng Zhan. Serum starvation-induces down-regulation of Bcl-2/Bax confers apoptosis in tongue coating-related cells in vitro. Molecular medicine reports. vol 17. issue 4. 2018-08-27. PMID:29393442. |
mtt assays revealed that serum‑starvation results in suppression of cellular proliferation, while flow cytometry data revealed that serum‑starvation induces cell cycle arrest at g1 phase and increases apoptosis. |
2018-08-27 |
2023-08-13 |
Not clear |
| Yu-Yuan Qian, Zhi-Su Liu, Zidong Zhang, Anait S Levenson, Kun L. Pterostilbene increases PTEN expression through the targeted downregulation of microRNA-19a in hepatocellular carcinoma. Molecular medicine reports. vol 17. issue 4. 2018-08-27. PMID:29393488. |
the proliferation, apoptosis and cell cycle was analyzed in the smmc‑7721 hcc cell line by mtt assays and flow cytometry methods. |
2018-08-27 |
2023-08-13 |
Not clear |
| Zhi-Hua Ye, Ding-Wen Gu. miR‑539 suppresses proliferation and induces apoptosis in renal cell carcinoma by targeting high mobility group A2. Molecular medicine reports. vol 17. issue 4. 2018-08-27. PMID:29436648. |
cell viability and apoptosis were detected using mtt and flow cytometry assays. |
2018-08-27 |
2023-08-13 |
Not clear |
| Li-Ting Zhang, Xue-Bin Peng, Xue-Qin Fang, Jun-Feng Li, Hong Chen, Xiao-Rong Ma. Human umbilical cord mesenchymal stem cells inhibit proliferation of hepatic stellate cells in vitro. International journal of molecular medicine. vol 41. issue 5. 2018-08-27. PMID:29484382. |
cell proliferation and apoptosis were determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay and flow cytometry, respectively. |
2018-08-27 |
2023-08-13 |
human |