| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaoli Ren, Bingbing Zhao, Hongjian Chang, Min Xiao, Yuhong Wu, Yun Li. Paclitaxel suppresses proliferation and induces apoptosis through regulation of ROS and the AKT/MAPK signaling pathway in canine mammary gland tumor cells. Molecular medicine reports. vol 17. issue 6. 2018-09-26. PMID:29658576. |
the aim of the present study was to investigate the antitumor effects of paclitaxel on chmm cells and identify relevant signal transduction pathways modulated by paclitaxel using multiple methods including mtt assay, flow cytometry, acridine orange/ethidium bromide staining, transmission electron microscopy, determination of cellular reactive oxygen species (ros), superoxide dismutase (sod) and malondiadehyde (mda) and western blotting, the data indicated that paclitaxel decreased cell viability, induced g2/m‑phase cell cycle arrest, suppressed the expression of cyclin b1 and induced apoptosis in a dose‑dependent manner. |
2018-09-26 |
2023-08-13 |
Not clear |
| Fei Wang, Chun-Qian Dai, Li-Rong Zhang, Cao Bing, Jun Qin, Yi-Fei Li. Downregulation of Lgr6 inhibits proliferation and invasion and increases apoptosis in human colorectal cancer. International journal of molecular medicine. vol 42. issue 1. 2018-09-26. PMID:29693156. |
then cell viability, apoptosis and cell invasion was measured by mtt, flow cytometry or matrigel‑transwell system, respectively in crc cells after transfected with lgr6 sirna or lgr6 vector. |
2018-09-26 |
2023-08-13 |
human |
| Minxia Ke, Quan He, Danping Hong, Ouyang Li, Mengyi Zhu, Wen-Bin Ou, Yulong He, Yuehong W. Leukemia inhibitory factor regulates marmoset induced pluripotent stem cell proliferation via a PI3K/Akt‑dependent Tbx‑3 activation pathway. International journal of molecular medicine. vol 42. issue 1. 2018-09-24. PMID:29620145. |
cell proliferation was measured using mtt assay, cell apoptosis was determined by flow cytometric analysis of fluorescein isothiocyanate annexin v staining and the differentially expressed genes were analysed using digital gene expression (dge) analysis. |
2018-09-24 |
2023-08-13 |
mouse |
| Qiang Feng, Tao Tian, Junfeng Liu, Li Zhang, Jiangang Qi, Xiaojuan Li. Deregulation of microRNA‑31a‑5p is involved in the development of primary hypertension by suppressing apoptosis of pulmonary artery smooth muscle cells via targeting TP53. International journal of molecular medicine. vol 42. issue 1. 2018-09-24. PMID:29620173. |
a mtt assay and flow cytometric analysis were utilized to determine the effect of mir‑31a‑5p on cell growth and apoptosis. |
2018-09-24 |
2023-08-13 |
rat |
| Zhichun Liu, Jingwu Sun, Bin Liu, Mengjie Zhao, Entao Xing, Cunshu Dan. miRNA‑222 promotes liver cancer cell proliferation, migration and invasion and inhibits apoptosis by targeting BBC3. International journal of molecular medicine. vol 42. issue 1. 2018-09-24. PMID:29693134. |
cell proliferation, apoptosis, cell cycle, migration and invasion were evaluated by an mtt assay, flow cytometry, wound healing assay and transwell assay, respectively. |
2018-09-24 |
2023-08-13 |
Not clear |
| Naixin Ding, Xiujin Sun, Tingting Wang, Lei Huang, Jing Wen, Yiqin Zho. miR‑378a‑3p exerts tumor suppressive function on the tumorigenesis of esophageal squamous cell carcinoma by targeting Rab10. International journal of molecular medicine. vol 42. issue 1. 2018-09-24. PMID:29693138. |
in addition, the effects of mir‑378a‑3p on cell viability, proliferation, apoptosis, migration and invasion were studied using an mtt assay, an edu assay, flow cytometry analysis, wound healing analysis and a transwell assay. |
2018-09-24 |
2023-08-13 |
Not clear |
| Anping Lin, Juan Yin, Chao Cheng, Zhu Yang, Huan Yan. Decreased expression of FOXA2 promotes eutopic endometrial cell proliferation and migration in patients with endometriosis. Reproductive biomedicine online. vol 36. issue 2. 2018-09-21. PMID:29233503. |
mtt assay showed that cell viability of esc with transfected foxa2 sirna increased significantly, whereas the apoptosis rate decreased as indicated by flow cytometry experiments (both p < 0.05). |
2018-09-21 |
2023-08-13 |
Not clear |
| Shuwei Zhang, Yu Ren, Jianxin Qi. Dauricine inhibits viability and induces cell cycle arrest and apoptosis via inhibiting the PI3K/Akt signaling pathway in renal cell carcinoma cells. Molecular medicine reports. vol 17. issue 5. 2018-09-21. PMID:29568902. |
the effects of dauricine on viability, cell cycle distribution and apoptosis in rcc cells were determined in vitro by mtt assay, flow cytometry and nucleosome elisa assay, respectively. |
2018-09-21 |
2023-08-13 |
Not clear |
| Jun Yang, Linna Li, Chengwang Xu, Dexuan Yang, Shanshan Wang, Shoujun Yua. CT‑1042, a novel anticancer agent, exhibits effects by activating p53 and inhibiting survivin. Oncology reports. vol 39. issue 6. 2018-09-21. PMID:29620221. |
a thiazolyl blue tetrazolium bromide assay (mtt) was performed to evaluate cell viability and flow cytometry was used to analyze apoptosis, mitochondrial membrane potential (mmp) and cell cycle. |
2018-09-21 |
2023-08-13 |
human |
| Subramanyam Dasari, Angela Lincy Prem Antony Samy, Parnal Narvekar, Venkata Satish Dontaraju, Ramesh Dasari, Alexander Kornienko, Gnanasekar Munirathina. Polygodial analog induces apoptosis in LNCaP prostate cancer cells. European journal of pharmacology. vol 828. 2018-09-19. PMID:29572068. |
we evaluated the anti-cancer potential of the pg analog namely drp-27 using various assays such as cell viability by mtt assay, anchorage independent growth by soft agar assay, reactive oxygen species generation by 2',7'-dichlorofluorescein probe-based fluorescence assay, and apoptosis by annexin-v and tunel assays respectively. |
2018-09-19 |
2023-08-13 |
Not clear |
| A Ilfergane, R R Henke. Effect of Typha capensis (Rohrb.)N.E.Br. rhizome extract F1 fraction on cell viability, apoptosis induction and testosterone production in TM3-Leydig cells. Andrologia. vol 50. issue 2. 2018-09-18. PMID:28719047. |
the following parameters were evaluated: cell morphology, viability (mtt assay), testosterone production (testosterone elisa test), apoptosis (annexin v-cy3 binding) and dna fragmentation (tunel assay). |
2018-09-18 |
2023-08-13 |
Not clear |
| Anna Bielecka-Kowalska, Piotr Czarny, Paulina Wigner, Ewelina Synowiec, Bartosz Kowalski, Marzena Szwed, Renata Krupa, Monika Toma, Malgorzata Drzewiecka, Ireneusz Majsterek, Janusz Szemraj, Tomasz Sliwinski, Michał Kowalsk. Ethylene glycol dimethacrylate and diethylene glycol dimethacrylate exhibits cytotoxic and genotoxic effect on human gingival fibroblasts via induction of reactive oxygen species. Toxicology in vitro : an international journal published in association with BIBRA. vol 47. 2018-09-18. PMID:29107684. |
both monomers were found to reduce cells viability in mtt assay, increase apoptosis and cause cell cycle arrest in g1/g0 phase. |
2018-09-18 |
2023-08-13 |
human |
| Iman Jamhiri, Saber Zahri, Davood Mehrabani, Zahra Khodabandeh, Mehdi Dianatpour, Ramin Yaghobi, Seyed Younes Hossein. Enhancing the apoptotic effect of IL-24/mda-7 on the human hepatic stellate cell through RGD peptide modification. Immunological investigations. vol 47. issue 4. 2018-09-18. PMID:29498551. |
cell viability and the amount of apoptosis were analyzed using mtt and annexin v staining method, respectively. |
2018-09-18 |
2023-08-13 |
human |
| Qiaoxian Huang, Shengke Li, Yuan-Fu Ding, Hang Yin, Lian-Hui Wang, Ruibing Wan. Macrocycle-wrapped polyethylenimine for gene delivery with reduced cytotoxicity. Biomaterials science. vol 6. issue 5. 2018-09-18. PMID:29557458. |
as a consequence of the supramolecular wrapping, the cytotoxicity of pei was significantly constrained as demonstrated by mtt assay, apoptosis assay, and a hemolysis study. |
2018-09-18 |
2023-08-13 |
Not clear |
| Xiaoli Li, Jian Liu, Li Qian, Honggang Ke, Chan Yao, Wei Tian, Yifei Liu, Jianguo Zhan. Expression of PFKFB3 and Ki67 in lung adenocarcinomas and targeting PFKFB3 as a therapeutic strategy. Molecular and cellular biochemistry. vol 445. issue 1-2. 2018-09-17. PMID:29327288. |
cell viability, cell cycle, cell apoptosis, cell migration, and invasion were analyzed by mtt, flow cytometry, western blot analysis, wound healing assay, and transwell chamber assay. |
2018-09-17 |
2023-08-13 |
human |
| Bin Xiao, Xuan Zhang, Mei-lan Zhang, Xue-wu Zhan. [Apoptosis of human hepatocellular carcinoma HepG-2 cells upon inhibition of STAT3 by 5,2’,4’-trihydroxy-6,7,5’-trimethoxy flavone nanoparticle]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 51. issue 12. 2018-09-17. PMID:29908536. |
mtt assay, immunocytochemical staining and flow cytometry with annexin v-fitc/pi were used to demonstrate inhibition of proliferation of hepg-2 cells and cell apoptosis. |
2018-09-17 |
2023-08-13 |
human |
| Yanwu Hu, Haitao Li, Kai Liu, Yang Zhang, Liqun Ren, Zhimin Fa. Protective effects of icariin on human vascular endothelial cells induced by oxidized low-density lipoprotein via modulating caspase-3 and Bcl-2. Molecular medicine reports. vol 17. issue 5. 2018-09-13. PMID:29532884. |
the viability of cells was evaluated via an mtt assay and flow cytometry was performed to assess apoptosis. |
2018-09-13 |
2023-08-13 |
human |
| Jamal Akhtar Ansari, Mohammad Kaleem Ahmad, Abdul Rahman Khan, Nishat Fatima, Homa Jilani Khan, Namrata Rastogi, Durga Prasad Mishra, Abbas Ali Mahd. Anticancer and Antioxidant activity of Zingiber officinale Roscoe rhizome. Indian journal of experimental biology. vol 54. issue 11. 2018-09-13. PMID:30179422. |
antiproliferative activity was substantiated by 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide (mtt) and colony formation assay for cell viability and cell proliferation, hoechst staining was performed to examine apoptosis. |
2018-09-13 |
2023-08-13 |
human |
| Jiawen You, Jun Cheng, Bing Yu, Changhua Duan, Jinghua Pen. Baicalin, a Chinese Herbal Medicine, Inhibits the Proliferation and Migration of Human Non-Small Cell Lung Carcinoma (NSCLC) Cells, A549 and H1299, by Activating the SIRT1/AMPK Signaling Pathway. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2018-09-11. PMID:29632297. |
the mtt assay was used to determine cell viability, flow cytometry was used to measure cell apoptosis, wound healing and transwell assays were used to assess cell migration of a549 and h1299 cells. |
2018-09-11 |
2023-08-13 |
human |
| Hong Zhang, Hua-Li Xu, Yu-Chen Wang, Ze-Yuan Lu, Xiao-Feng Yu, Da-Yun Su. 20(S)-Protopanaxadiol-Induced Apoptosis in MCF-7 Breast Cancer Cell Line through the Inhibition of PI3K/AKT/mTOR Signaling Pathway. International journal of molecular sciences. vol 19. issue 4. 2018-09-10. PMID:29614812. |
cell viability and apoptosis were evaluated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt)-test and annexin v /pi double-staining after transfection. |
2018-09-10 |
2023-08-13 |
mouse |