| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sadegh Fattahi, Elham Ghadami, Mohsen Asouri, Ali Motevalizadeh Ardekanid, Haleh Akhavan-Niak. Urtica dioica inhibits cell growth and induces apoptosis by targeting Ornithine decarboxylase and Adenosine deaminase as key regulatory enzymes in adenosine and polyamines homeostasis in human breast cancer cell lines. Cellular and molecular biology (Noisy-le-Grand, France). vol 64. issue 3. 2018-08-27. PMID:29506637. |
cells viability was assessed by mtt assay, and apoptosis was also evaluated at cellular level. |
2018-08-27 |
2023-08-13 |
human |
| Yang Yang, Yanchao Deng, Xiangcui Chen, Jiahao Zhang, Yueming Chen, Huachao Li, Qipeng Wu, Zhicheng Yang, Luyong Zhang, Bing Li. Inhibition of PDGFR by CP-673451 induces apoptosis and increases cisplatin cytotoxicity in NSCLC cells via inhibiting the Nrf2-mediated defense mechanism. Toxicology letters. vol 295. 2018-08-27. PMID:29857117. |
however, cp-673451 exerted less cytotoxicity in normal lung epithelial cell line beas-2b cells determined by mtt and apoptosis assay. |
2018-08-27 |
2023-08-13 |
Not clear |
| Fei Qu, Xiufen Wan. microRNA-340 induces apoptosis by downregulation of BAG3 in ovarian cancer SKOV3 cells. Die Pharmazie. vol 72. issue 8. 2018-08-24. PMID:29441908. |
thereafter, cell viability, apoptosis, and the expressions of apoptosis-associated factors and bag3 were respectively assessed by mtt assay, flow cytometry, qrt-pcr and western blotting. |
2018-08-24 |
2023-08-13 |
human |
| S Q Ji, Y X Zhang, B H Yan. UBR5 promotes cell proliferation and inhibits apoptosis in colon cancer by destablizing P21. Die Pharmazie. vol 72. issue 7. 2018-08-24. PMID:29441938. |
then mtt and flow cytometry were used to explore the proliferation and apoptosis in a colon cancer cell line in vitro. |
2018-08-24 |
2023-08-13 |
Not clear |
| Shi-Xiang Yuan, Jun-Liang Li, Xin-Ke Xu, Wei Chen, Cheng Chen, Kun-Qi Kuang, Fang-Yu Wang, Kai Wang, Fang-Cheng L. Underlying mechanism of the photodynamic activity of hematoporphyrin‑induced apoptosis in U87 glioma cells. International journal of molecular medicine. vol 41. issue 4. 2018-08-23. PMID:29344634. |
the photodynamic activity of hematoporphyrin on the cell viability and apoptosis of gliomas was investigated by mtt, and flow cytometry and fluorescence microscopy, respectively. |
2018-08-23 |
2023-08-13 |
Not clear |
| Xiaocui Chen, Yinghua Xu, Zuowang Cheng, Hong Su, Xiu Liu, Dongmei Xu, Carolyn Kapron, Ju Li. Low-dose cadmium activates the JNK signaling pathway in human renal podocytes. International journal of molecular medicine. vol 41. issue 4. 2018-08-23. PMID:29393374. |
proliferation, viability and apoptosis of hrps were evaluated by mtt assay, trypan blue exclusion assay and flow cytometry, respectively. |
2018-08-23 |
2023-08-13 |
human |
| Weiping Zhang, Jianming X. Adaptive unfolded protein response promotes cell survival in rifampicin-treated L02 cells. International journal of molecular medicine. vol 41. issue 4. 2018-08-23. PMID:29393386. |
moreover, fca showed that cell apoptosis rate obviously increased, and mtt assay showed that cell survival rate obviously decreased, this indicates that after inhibiting the upr, the cell damage increased, which shows that the upr is an adaptation mechanism to protect cells against injury induced by rfp. |
2018-08-23 |
2023-08-13 |
Not clear |
| Ke Chen, Liang Cheng, Weikun Qian, Zhengdong Jiang, Liankang Sun, Yanfei Zhao, Yongsheng Zhou, Lizhi Zhao, Pengli Wang, Wanxing Duan, Qingyong Ma, Wei Yan. Itraconazole inhibits invasion and migration of pancreatic cancer cells by suppressing TGF-β/SMAD2/3 signaling. Oncology reports. vol 39. issue 4. 2018-08-23. PMID:29484419. |
effects of itz on cell proliferation, apoptosis, invasion and migration were observed by mtt assays and colony formation assays, flow cytometry, wound scratch assays and transwell assays, respectively. |
2018-08-23 |
2023-08-13 |
mouse |
| Jiexiang Yang, Yonggen Zou, Dianmin Jian. Honokiol suppresses proliferation and induces apoptosis via regulation of the miR‑21/PTEN/PI3K/AKT signaling pathway in human osteosarcoma cells. International journal of molecular medicine. vol 41. issue 4. 2018-08-21. PMID:29393336. |
the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay and flow cytometric analysis were used to evaluate the cell proliferation and apoptosis in human os cells after treatment with hnk, respectively. |
2018-08-21 |
2023-08-13 |
human |
| Jignesh Lunagariya, Xiaojian Liao, Weili Long, Shenghui Zhong, Poonam Bhadja, Hangbin Li, Bingxin Zhao, Shihai X. Cytotoxicity Study of Cyclopentapeptide Analogues of Marine Natural Product Galaxamide towards Human Breast Cancer Cells. Oxidative medicine and cellular longevity. vol 2017. 2018-08-21. PMID:29410736. |
we examined the effect of the novel galaxamide analogues on cancer cell proliferation by mtt assay and also further examined the most active compound for morphological changes using hoechst33342 staining technique, induction of apoptosis, cell cycle phases, mitochondrial membrane potential (mmp), and reactive oxygen species (ros) generation using flow cytometry in human breast cancer mcf-7 cells |
2018-08-21 |
2023-08-13 |
human |
| Thomas Gehrke, Stephan Hackenberg, Bülent Polat, Gisela Wohlleben, Rudolf Hagen, Norbert Kleinsasser, Agmal Scherza. Combination of salinomycin and radiation effectively eliminates head and neck squamous cell carcinoma cells in vitro. Oncology reports. vol 39. issue 4. 2018-08-21. PMID:29436675. |
subsequently, analysis of cell viability, apoptosis, necrosis and motility through an mtt and a colony formation assay, as well as an annexin v/propidium-iodide test, a consecutive cell count for four days and a scratch assay were conducted. |
2018-08-21 |
2023-08-13 |
Not clear |
| Jin-Wu Chen, Ying-Jia Luo, Zheng-Fei Yang, Li-Qiang Wen, Lin Huan. Knockdown of angiopoietin-like 4 inhibits the development of human gastric cancer. Oncology reports. vol 39. issue 4. 2018-08-21. PMID:29436683. |
following angptl4 downregulation, the proliferation and invasion abilities of gc cell lines were suppressed as determined by mtt and transwell assays, and cell apoptosis level and sensitivity to cisplatin were increased as determined by flow cytometry and mtt assay. |
2018-08-21 |
2023-08-13 |
human |
| Lixue Zou, Jun Liu, Hougen L. Influence of protein kinase RIPK4 expression on the apoptosis and proliferation of chondrocytes in osteoarthritis. Molecular medicine reports. vol 17. issue 2. 2018-08-20. PMID:29257245. |
chondrocytes proliferation was detected by mtt assay, cell apoptosis was indicated using flow cytometry and wnt/β‑catenin signaling pathway related‑proteins were investigated using western blot analysis. |
2018-08-20 |
2023-08-13 |
Not clear |
| Liqiao Fan, Bibo Tan, Yong Li, Qun Zhao, Hufang Yuan, Yu Liu, Dong Wang, Zhidong Zhan. Upregulation of miR‑185 promotes apoptosis of the human gastric cancer cell line MGC803. Molecular medicine reports. vol 17. issue 2. 2018-08-20. PMID:29257260. |
post‑transfection, the following experiments were conducted: mtt assay was applied to test cell viability; flow cytometry (fcm) was used to determine the apoptotic rate of the cells; and qpcr and western blotting were conducted to detect the expression levels of the following apoptosis‑associated factors: b‑cell lymphoma 2 (bcl‑2), bcl‑2‑associated x protein (bax), survivin, x‑linked inhibitor of apoptosis protein (xiap), livin, caspase‑3 and caspase‑8. |
2018-08-20 |
2023-08-13 |
human |
| Shenwen Liu, Sheng Chen, Jing Ren, Baijun Li, Bo Qi. Ghrelin protects retinal ganglion cells against rotenone via inhibiting apoptosis, restoring mitochondrial function, and activating AKT-mTOR signaling. Neuropeptides. vol 67. 2018-08-16. PMID:29174113. |
cell viability and cell apoptosis were determined by mtt assay and flow cytometry, respectively. |
2018-08-16 |
2023-08-13 |
rat |
| Lufang Wang, Yanyan Zhao, Qiong Wu, Yifu Guan, Xin W. Therapeutic effects of β-elemene via attenuation of the Wnt/β-catenin signaling pathway in cervical cancer cells. Molecular medicine reports. vol 17. issue 3. 2018-08-16. PMID:29363722. |
cell viability, cell cycle progression and apoptosis were detected using an mtt assay and flow cytometry analysis. |
2018-08-16 |
2023-08-13 |
human |
| Xin Jin, Wenchao Zhao, Peng Zhou, Tianli Ni. YAP knockdown inhibits proliferation and induces apoptosis of human prostate cancer DU145 cells. Molecular medicine reports. vol 17. issue 3. 2018-08-14. PMID:29286134. |
an mtt assay and flow cytometry were performed to investigate the proliferation and apoptosis of du145 cells. |
2018-08-14 |
2023-08-13 |
human |
| Yang Yang, Yawei Wang, Meng Zhao, Haobo Jia, Bing Li, Dan Xin. Tormentic acid inhibits IL-1β-induced chondrocyte apoptosis by activating the PI3K/Akt signaling pathway. Molecular medicine reports. vol 17. issue 3. 2018-08-14. PMID:29328385. |
cell viability was determined using the mtt assay, and cell apoptosis was detected using a nucleosome elisa kit. |
2018-08-14 |
2023-08-13 |
human |
| Shuhai Sheng, Jinji Zhang, Jianzhong Ai, Xueli Hao, Ruishen Lua. Aberrant expression of IL-23/IL-23R in patients with breast cancer and its clinical significance. Molecular medicine reports. vol 17. issue 3. 2018-08-14. PMID:29328397. |
cell proliferation assay and cell apoptosis assay were evaluated using mtt assay and flow cytometry assay, respectively. |
2018-08-14 |
2023-08-13 |
human |
| Qi Wang, Fenxi Zhang, Yan Hon. Blocking of autocrine IGF-1 reduces viability of human umbilical cord mesenchymal stem cells via inhibition of the Akt/Gsk-3β signaling pathway. Molecular medicine reports. vol 17. issue 3. 2018-08-14. PMID:29344668. |
cell viability, apoptosis, cell cycle and the proliferation‑associated proteins were quantified using an mtt assay, flow cytometry and western blotting. |
2018-08-14 |
2023-08-13 |
human |