| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zefei Wang, Chunzhi Yu, Hong Wan. HOXA5 inhibits the proliferation and induces the apoptosis of cervical cancer cells via regulation of protein kinase B and p27. Oncology reports. vol 41. issue 2. 2019-02-04. PMID:30483748. |
we performed a gain‑of‑function experiment by the transfection with pcdna.3.1‑hoxa5 in me‑180 and ht‑3 cells to overexpress hoxa5, and the caspase‑3 activity measured by caspase‑3 activity assay kit and cell apoptosis detected by flow cytometry were obviously promoted. |
2019-02-04 |
2023-08-13 |
Not clear |
| Xiaoqing Liu, Dwayne M Hansen, Noah J Timko, Ziwen Zhu, Andrew Ames, Chenglu Qin, Michael B Nicholl, Qian Bai, Xuhui Chen, Mark R Wakefield, Gage West, Yujiang Fan. Association between interleukin‑33 and ovarian cancer. Oncology reports. vol 41. issue 2. 2019-02-04. PMID:30535474. |
a clonogenic survival assay, immunohistochemistry (ihc), proliferation kit and caspase‑3 activity kit were all used to evaluate the direct effects of il‑33 on cell proliferation and apoptosis of a widely studied ovarian cancer cell line, a2780. |
2019-02-04 |
2023-08-13 |
Not clear |
| Xinyu Hu, Shanshan Teng, Jiawei He, Xiaoqi Sun, Mingzhao Du, Ling Kou, Xiaofeng Wan. Pharmacological basis for application of scutellarin in Alzheimer's disease: Antioxidation and antiapoptosis. Molecular medicine reports. vol 18. issue 5. 2019-01-29. PMID:30221730. |
in l‑glu‑damaged ht22 cells, sc significantly increased cell viability, inhibited lactate dehydrogenase release, reduced caspase‑3 activity and suppressed apoptosis, which were determined via an mtt assay, an in vitro toxicology assay kit, a caspase‑3 activity assay kit, and propidium iodide and annexin v staining. |
2019-01-29 |
2023-08-13 |
mouse |
| Wamidh H Talib, Lina T Al Kur. Parthenolide inhibits tumor-promoting effects of nicotine in lung cancer by inducing P53 - dependent apoptosis and inhibiting VEGF expression. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 107. 2019-01-22. PMID:30257366. |
angiogenesis inhibition was measured using vegf detection kit and apoptosis induction was evaluated by measuring caspase-3 activity. |
2019-01-22 |
2023-08-13 |
Not clear |
| Mohammadreza Gholami, Abolfazl Abbaszadeh, Parastoo Baharvand, Afshin Hasanvand, Amin Hasanvand, Anneh Mohammad Gharrav. Protective effects of persian honey, Apis Mellifera Meda Skorikov on side effects of chemotherapy and ischemia/reperfusion induced testicular injury. Journal of complementary & integrative medicine. vol 15. issue 4. 2019-01-11. PMID:29791311. |
detection of single- and double-stranded dna breaks at the early stages of apoptosis was performed using the in-situ cell death detection kit. |
2019-01-11 |
2023-08-13 |
rat |
| Yujing Yang, Yanli Xu, Ailing Su, Dan Yang, Xuezhong Zhan. Effects of Deferoxamine on Leukemia In Vitro and Its Related Mechanism. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2018-12-12. PMID:30246777. |
cck-8 kit and flow cytometry were used for cell viability and apoptosis detection. |
2018-12-12 |
2023-08-13 |
Not clear |
| Ozgur Kaplan, Gunnur Demirca. Relationship of Autophagy and Apoptosis with Total Occlusion of Coronary Arteries. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2018-12-12. PMID:30273932. |
we used the enzyme-linked immunosorbent assay (elisa) kit for autophagy-related protein 5 (atg5) and apoptosis (m30) in the plasma for these 3 groups. |
2018-12-12 |
2023-08-13 |
Not clear |
| Nazim Hussain, Wenhua Zhu, Congshan Jiang, Jing Xu, Manman Geng, Xiaoying Wu, Safdar Hussain, Bo Wang, Muhammad Shahid Riaz Rajoka, Yue Li, Juan Tian, Liesu Meng, Shemin L. Down-regulation of miR-10a-5p promotes proliferation and restricts apoptosis via targeting T-box transcription factor 5 in inflamed synoviocytes. Bioscience reports. vol 38. issue 2. 2018-12-11. PMID:29545315. |
further, the proliferation and apoptosis of sw982 cells after treatment were determined by cell counting kit (cck-8) and flow cytometry analysis respectively. |
2018-12-11 |
2023-08-13 |
human |
| Ruifang Wu, Yuan Liao, Weiyun Shen, Yu Liu, Jianzhong Zhang, Min Zheng, Genghui Chen, Yuwen Su, Ming Zhao, Qianjin L. Overexpression of Wilms' tumor 1 in skin lesions of psoriasis is associated with abnormal proliferation and apoptosis of keratinocytes. Molecular medicine reports. vol 18. issue 4. 2018-12-11. PMID:30132523. |
wt1 was stably overexpressed or inhibited in hacat cells using lipofectamine® 2000, and cell proliferation and apoptosis were determined using a cell counting kit‑8 or fluorescein isothiocyanate annexin v apoptosis detection kit ii, respectively. |
2018-12-11 |
2023-08-13 |
mouse |
| Yanwu Sun, Yiyi Zhang, Pan Ch. Pirfenidone suppresses TGF‑β1‑induced human intestinal fibroblasts activities by regulating proliferation and apoptosis via the inhibition of the Smad and PI3K/AKT signaling pathway. Molecular medicine reports. vol 18. issue 4. 2018-12-11. PMID:30152848. |
cell proliferation was determined by cell counting kit (cck)‑8 and colony formation assays, and cell apoptosis was assessed using flow cytometry and a tunel assay. |
2018-12-11 |
2023-08-13 |
human |
| Ying Yang, Xiong Tao, Chun-Bo Li, Chang-Miao Wan. MicroRNA-494 acts as a tumor suppressor in pancreatic cancer, inhibiting epithelial-mesenchymal transition, migration and invasion by binding to SDC1. International journal of oncology. vol 53. issue 3. 2018-11-26. PMID:29956739. |
cell proliferation was assessed using a cell counting kit (cck)‑8 assay, migration was measured using a scratch test, invasion was assessed with a transwell assay and apoptosis was detected by flow cytometry. |
2018-11-26 |
2023-08-13 |
mouse |
| Hui-Jen Tsai, Weir-Torn Jiaang, Neng-Yao Shih, Jonathan A Fletcher, Ming-Jon Lin, Ming-Yu Yang, Chiung-Tong Chen, Tsu-An John Hsu, Chun-Chieh Wu, Hui-You Lin, Li-Tzong Che. BPR1J373, a novel multitargeted kinase inhibitor, effectively suppresses the growth of gastrointestinal stromal tumor. Cancer science. vol 109. issue 11. 2018-11-19. PMID:30142229. |
in this study, we found that bpr1j373 inhibited proliferation and induced apoptosis by targeting kit in gist cells with kit gene mutations. |
2018-11-19 |
2023-08-13 |
mouse |
| Dong Wang, Xinjie Zhang, Daoxu Qu, Jichun Han, Fanqing Meng, Minglei Xu, Qiusheng Zhen. Astragalin and dihydromyricetin as adjuncts to histidine‑tryptophan‑ketoglutarate cardioplegia enhances protection during cardioplegic arrest. Molecular medicine reports. vol 18. issue 3. 2018-11-08. PMID:30015889. |
cardiomyocyte apoptosis analysis was performed using an in situ cell death detection kit. |
2018-11-08 |
2023-08-13 |
rat |
| Xiao-Yin Tan, Xin Wang, Qing-Song Liu, Xiao-Qian Xie, Yi Li, Bing-Qian Li, Zhi-Qing Li, Qing-You Xia, Ping Zha. Inhibition of silkworm vacuolar-type ATPase activity by its inhibitor Bafilomycin A1 induces caspase-dependent apoptosis in an embryonic cell line of silkworm. Archives of insect biochemistry and physiology. vol 99. issue 3. 2018-11-05. PMID:30246413. |
cell counting kit 8 (cck8) and flow cytometry analysis showed that bafilomycin a1 treatment decreased the cell proliferation activity, affected the cell cycle progression and induced cell apoptosis. |
2018-11-05 |
2023-08-13 |
Not clear |
| Huan Zhai, Xun Qi, Zixuan Li, Wei Zhang, Chenguang Li, Lu Ji, Ke Xu, Hongshan Zhon. TIMP‑3 suppresses the proliferation and migration of SMCs from the aortic neck of atherosclerotic AAA in rabbits, via decreased MMP‑2 and MMP‑9 activity, and reduced TNF‑α expression. Molecular medicine reports. vol 18. issue 2. 2018-10-19. PMID:29956789. |
cell proliferation was investigated using cell counting kit‑8 reagent, migration was examined using a boyden chamber assay and apoptotic rate was analyzed using the annexin v‑fluorescein isothiocyanate apoptosis detection kit. |
2018-10-19 |
2023-08-13 |
rabbit |
| Qingkai Meng, Yue Chen, Bo Lian, Yan Shang, Hongmei Yan. miR‑218 promotes apoptosis of SW1417 human colon cancer cells by targeting c‑FLIP. Oncology reports. vol 40. issue 2. 2018-10-12. PMID:29845219. |
following overexpression of mir‑218 in human colon cancer cells, cell viability was determined by ckk‑8 assay, cell apoptosis was observed using a tunel kit, the expression of caspase‑8, and its inhibitor cellular fas‑associated death domain‑like interleukin‑1β‑converting enzyme inhibitory protein (c‑flip) was assessed by rt‑pcr, western blot analysis and immunohistochemistry. |
2018-10-12 |
2023-08-13 |
human |
| Ting Li, Qingwen Zeng, Xingming Chen, Guojiang Wang, Haiqing Zhang, Aihua Yu, Hairui Wang, Yang H. The therapeutic effect of artesunate on rosacea through the inhibition of the JAK/STAT signaling pathway. Molecular medicine reports. vol 17. issue 6. 2018-09-26. PMID:29693177. |
cell counting kit 8 and flow cytometry assays were performed to measure cellular proliferation, apoptosis, the stage of the cell cycle and reactive oxygen species generation in order to determine the level of cell damage. |
2018-09-26 |
2023-08-13 |
Not clear |
| Min Dai, Qing Zhang, Zhikun Zheng, Jianzhou Wan. Retinal ganglion cell-conditioned medium and surrounding pressure alters gene expression and differentiation of rat retinal progenitor cells. Molecular medicine reports. vol 17. issue 5. 2018-09-21. PMID:29568879. |
cellular apoptosis was detected using a caspase‑3 assay kit. |
2018-09-21 |
2023-08-13 |
rat |
| Bin-Bin Yu, Guo-Xiang Lin, Ling Li, Song Qu, Zhong-Guo Liang, Kai-Hua Chen, Lei Zhou, Qi-Teng Lu, Yong-Chu Sun, Xiao-Dong Zh. Cofilin-2 Acts as a Marker for Predicting Radiotherapy Response and Is a Potential Therapeutic Target in Nasopharyngeal Carcinoma. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2018-09-18. PMID:29664897. |
then, cell proliferation, radiosensitivity, invasion and migration abilities, cell cycle, and apoptosis were evaluated by cell counting kit 8 assay (cck-8), flow cytometry (fcm), clone formation assay, and in vitro. |
2018-09-18 |
2023-08-13 |
mouse |
| Xiaochen Fan, Jishan Yuan, Jun Xie, Zhanpeng Pan, Xiang Yao, Xiangyi Sun, Pin Zhang, Lei Zhan. Long non-protein coding RNA DANCR functions as a competing endogenous RNA to regulate osteoarthritis progression via miR-577/SphK2 axis. Biochemical and biophysical research communications. vol 500. issue 3. 2018-09-14. PMID:29678573. |
the effects of dancr on the viability of oa chondrocytes and apoptosis were explored using cell counting kit 8 assay and flow cytometry assay, respectively. |
2018-09-14 |
2023-08-13 |
Not clear |