| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S H Huang, T Zhang, C G Zhao, J Qin, P Qi, F T Li, X J H. Aclidinium bromide inhibits human glioma cell proliferation, migration and invasion and promotes apoptosis via the PI3K/AKT signaling pathway. Neoplasma. vol 65. issue 6. 2019-07-01. PMID:29940755. |
glioblastoma cell lines u251 and u87 were treated with inn and its effects on cell migration and invasion were assessed by transwell migration and invasion assays., the effects of inn on proliferation and apoptosis were detected by cck-8 kit and flow cytometry, and western blotting determined anti-apoptotic proteins and signaling pathway changes. |
2019-07-01 |
2023-08-13 |
human |
| Qianqian Yang, Gaoying Sun, Haiyan Yin, Hongrui Li, Zhixin Cao, Jinghan Wang, Meijuan Zhou, Haibo Wang, Jianfeng L. PINK1 Protects Auditory Hair Cells and Spiral Ganglion Neurons from Cisplatin-induced Ototoxicity via Inducing Autophagy and Inhibiting JNK Signaling Pathway. Free radical biology & medicine. vol 120. 2019-06-25. PMID:29458150. |
cell viability and apoptosis were examined by cck8 assay, tunel staining and annexin v apoptosis detection kit, respectively. |
2019-06-25 |
2023-08-13 |
mouse |
| Junfeng Luo, Zhengda Lou, Junzheng Zhen. Targeted regulation by ROCK2 on bladder carcinoma via Wnt signaling under hypoxia. Cancer biomarkers : section A of Disease markers. vol 24. issue 1. 2019-06-11. PMID:30475758. |
cell apoptosis was measured by caspase3 activity assay kit and transwell chamber measured cell migration. |
2019-06-11 |
2023-08-13 |
Not clear |
| Jun Li, Jianping Zhen. Theaflavins prevent cartilage degeneration via AKT/FOXO3 signaling in vitro. Molecular medicine reports. vol 19. issue 2. 2019-05-28. PMID:30569095. |
cell counting kit (cck‑8) was used to determine cell viability, and flow cytometric analysis was used to detect ros, apoptosis and dna damage. |
2019-05-28 |
2023-08-13 |
Not clear |
| Farzaneh Sadat Hosseini, Mojgan Noroozi Karimabad, Mohammad Reza Hajizadeh, Alireza Khoshdel, Soudeh Khanamani Falahati-Pour, Mohammad Reza Mirzaei, Seyed Mehdi Mirmohamadi, Mehdi Mahmood. Evaluating of Induction of Apoptosis by Cornus mass L. Extract in the Gastric Carcinoma Cell Line (AGS) Asian Pacific journal of cancer prevention : APJCP. vol 20. issue 1. 2019-05-17. PMID:30678391. |
making use of the apoptosis detection kit of annexin v-fitc, pi anddouble staining with annexin v-fitc were carried out for flow cytometry investigations. |
2019-05-17 |
2023-08-13 |
Not clear |
| Dong Wang, Liang Tang, Huihui Wu, Kai Wang, Dongyun G. MiR-127-3p inhibits cell growth and invasiveness by targeting ITGA6 in human osteosarcoma. IUBMB life. vol 70. issue 5. 2019-05-03. PMID:29573114. |
the biological functions of mir-127-3p and itga6 in os were investigated by following experiments: cell counting kit 8 (cck-8) and colony formation assays to inspect cell proliferation, flow cytometry, and caspase 3 activity assay to examine apoptosis, and transwell and wound healing assays to analyze invasion and migration. |
2019-05-03 |
2023-08-13 |
human |
| Chuan Cao, Wenping Wang, Lele Lu, Liang Wang, XiaoSong Chen, Rui Guo, Shirong Li, Junzi Jian. Inactivation of Beclin-1-dependent autophagy promotes ursolic acid-induced apoptosis in hypertrophic scar fibroblasts. Experimental dermatology. vol 27. issue 1. 2019-04-08. PMID:28767174. |
in our study, ua was used to treat hsfbs and the cell viability, apoptosis, and collagen synthesis were determined by a cell counting kit 8 assay, flow cytometry, and an h |
2019-04-08 |
2023-08-13 |
Not clear |
| Haiyan Ma, Dan Yan, Yina Wang, Wei Shi, Tianshu Liu, Chongqiang Zhao, Shengqi Huo, Jialin Duan, Jingwen Tao, Maocai Zhai, Pengcheng Luo, Junyi Guo, Lei Tian, Lulu Mageta, David Jou, Cuntai Zhang, Chenglong Li, Jiayuh Lin, Jiagao Lv, Sheng Li, Li Li. Bazedoxifene exhibits growth suppressive activity by targeting interleukin-6/glycoprotein 130/signal transducer and activator of transcription 3 signaling in hepatocellular carcinoma. Cancer science. vol 110. issue 3. 2019-03-08. PMID:30648776. |
apoptosis of cells was determined using the annexin v-fitc detection kit. |
2019-03-08 |
2023-08-13 |
mouse |
| Hui-Ping Ma, Wei-Xiang Kong, Xiu-Ying Li, Wei Li, Yan Zhang, Yan W. miRNA-223 is an anticancer gene in human non-small cell lung cancer through the PI3K/AKT pathway by targeting EGFR. Oncology reports. vol 41. issue 3. 2019-03-06. PMID:30747217. |
cell proliferation was measured using mtt assay, while cell apoptosis and caspase-3/9 activity were measured using flow cytometry and caspase-3/9 activity kit. |
2019-03-06 |
2023-08-13 |
human |
| Aifeng Zhang, Guoyun Wang, Lihua Jia, Tao Su, Lili Zhan. Exosome-mediated microRNA-138 and vascular endothelial growth factor in endometriosis through inflammation and apoptosis via the nuclear factor-κB signaling pathway. International journal of molecular medicine. vol 43. issue 1. 2019-03-05. PMID:30431056. |
cell apoptosis was measured using annexin v‑fitc/pi double staining apoptosis detection kit and dapi assays. |
2019-03-05 |
2023-08-13 |
mouse |
| Habib Ghaznavi, Samira Hosseini-Nami, S Kamran Kamrava, Rasoul Irajirad, Shayan Maleki, Ali Shakeri-Zadeh, Alireza Montazerabad. Folic acid conjugated PEG coated gold-iron oxide core-shell nanocomplex as a potential agent for targeted photothermal therapy of cancer. Artificial cells, nanomedicine, and biotechnology. vol 46. issue 8. 2019-02-20. PMID:28994325. |
cell death and apoptosis were evaluated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay and flow cytometry using an annexin v-fluorescein isothiocyanate/propidiumiodide apoptosis detection kit. |
2019-02-20 |
2023-08-13 |
human |
| Guoqing Ouyang, Zhipeng Liu, Li Xiong, Xiang Chen, Qinglong Li, He Huang, Liangwu Lin, Xiongying Miao, Lun Ma, Wei Chen, Yu We. [Role of PpIX-based photodynamic therapy in promoting the damage and apoptosis of colorectal cancer cell and its mechanisms]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 42. issue 8. 2019-02-04. PMID:28872077. |
to explore the effects of protoporphyrin ix (ppix)-mediated photodynamic therapy (pdt) on induction of apoptosis and death in colon cancer cell and the underlying mechanisms.
methods: the cell killing effect of pdt on hct116 cell was determined by cell counting kit (cck). |
2019-02-04 |
2023-08-13 |
Not clear |
| Zefei Wang, Chunzhi Yu, Hong Wan. HOXA5 inhibits the proliferation and induces the apoptosis of cervical cancer cells via regulation of protein kinase B and p27. Oncology reports. vol 41. issue 2. 2019-02-04. PMID:30483748. |
we performed a gain‑of‑function experiment by the transfection with pcdna.3.1‑hoxa5 in me‑180 and ht‑3 cells to overexpress hoxa5, and the caspase‑3 activity measured by caspase‑3 activity assay kit and cell apoptosis detected by flow cytometry were obviously promoted. |
2019-02-04 |
2023-08-13 |
Not clear |
| Xiaoqing Liu, Dwayne M Hansen, Noah J Timko, Ziwen Zhu, Andrew Ames, Chenglu Qin, Michael B Nicholl, Qian Bai, Xuhui Chen, Mark R Wakefield, Gage West, Yujiang Fan. Association between interleukin‑33 and ovarian cancer. Oncology reports. vol 41. issue 2. 2019-02-04. PMID:30535474. |
a clonogenic survival assay, immunohistochemistry (ihc), proliferation kit and caspase‑3 activity kit were all used to evaluate the direct effects of il‑33 on cell proliferation and apoptosis of a widely studied ovarian cancer cell line, a2780. |
2019-02-04 |
2023-08-13 |
Not clear |
| Xinyu Hu, Shanshan Teng, Jiawei He, Xiaoqi Sun, Mingzhao Du, Ling Kou, Xiaofeng Wan. Pharmacological basis for application of scutellarin in Alzheimer's disease: Antioxidation and antiapoptosis. Molecular medicine reports. vol 18. issue 5. 2019-01-29. PMID:30221730. |
in l‑glu‑damaged ht22 cells, sc significantly increased cell viability, inhibited lactate dehydrogenase release, reduced caspase‑3 activity and suppressed apoptosis, which were determined via an mtt assay, an in vitro toxicology assay kit, a caspase‑3 activity assay kit, and propidium iodide and annexin v staining. |
2019-01-29 |
2023-08-13 |
mouse |
| Wamidh H Talib, Lina T Al Kur. Parthenolide inhibits tumor-promoting effects of nicotine in lung cancer by inducing P53 - dependent apoptosis and inhibiting VEGF expression. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 107. 2019-01-22. PMID:30257366. |
angiogenesis inhibition was measured using vegf detection kit and apoptosis induction was evaluated by measuring caspase-3 activity. |
2019-01-22 |
2023-08-13 |
Not clear |
| Mohammadreza Gholami, Abolfazl Abbaszadeh, Parastoo Baharvand, Afshin Hasanvand, Amin Hasanvand, Anneh Mohammad Gharrav. Protective effects of persian honey, Apis Mellifera Meda Skorikov on side effects of chemotherapy and ischemia/reperfusion induced testicular injury. Journal of complementary & integrative medicine. vol 15. issue 4. 2019-01-11. PMID:29791311. |
detection of single- and double-stranded dna breaks at the early stages of apoptosis was performed using the in-situ cell death detection kit. |
2019-01-11 |
2023-08-13 |
rat |
| Yujing Yang, Yanli Xu, Ailing Su, Dan Yang, Xuezhong Zhan. Effects of Deferoxamine on Leukemia In Vitro and Its Related Mechanism. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2018-12-12. PMID:30246777. |
cck-8 kit and flow cytometry were used for cell viability and apoptosis detection. |
2018-12-12 |
2023-08-13 |
Not clear |
| Ozgur Kaplan, Gunnur Demirca. Relationship of Autophagy and Apoptosis with Total Occlusion of Coronary Arteries. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2018-12-12. PMID:30273932. |
we used the enzyme-linked immunosorbent assay (elisa) kit for autophagy-related protein 5 (atg5) and apoptosis (m30) in the plasma for these 3 groups. |
2018-12-12 |
2023-08-13 |
Not clear |
| Nazim Hussain, Wenhua Zhu, Congshan Jiang, Jing Xu, Manman Geng, Xiaoying Wu, Safdar Hussain, Bo Wang, Muhammad Shahid Riaz Rajoka, Yue Li, Juan Tian, Liesu Meng, Shemin L. Down-regulation of miR-10a-5p promotes proliferation and restricts apoptosis via targeting T-box transcription factor 5 in inflamed synoviocytes. Bioscience reports. vol 38. issue 2. 2018-12-11. PMID:29545315. |
further, the proliferation and apoptosis of sw982 cells after treatment were determined by cell counting kit (cck-8) and flow cytometry analysis respectively. |
2018-12-11 |
2023-08-13 |
human |