| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yanglei Li, Fang Shen, Yiqi Bao, Dongming Chen, Hong L. Apoptotic effects of rhein through the mitochondrial pathways, two death receptor pathways, and reducing autophagy in human liver L02 cells. Environmental toxicology. vol 34. issue 12. 2020-01-14. PMID:31436023. |
rhein was found to trigger apoptosis in l02 cells as shown by annexin v-fluoresceine isothiocyanate (fitc) apoptosis detection kit and cell mitochondrial membrane potential (mmp) assay, with nuclear morphological changes demonstrated by hoechst 33258 staining. |
2020-01-14 |
2023-08-13 |
human |
| Rong Yao, Lijuan Xu, Bin Wei, Zhaoye Qian, Jiru Wang, Hongxia Hui, Yuan Su. miR-142-5p regulates pancreatic cancer cell proliferation and apoptosis by regulation of RAP1A. Pathology, research and practice. vol 215. issue 6. 2020-01-10. PMID:31047726. |
in addition, cell-counting kit 8 (cck-8) and flow cytometry assays certified that mir-142-5p overexpression may inhibit pancreatic cancer cell proliferation but promote cell apoptosis; while the variation could be reversed by co-transfected with pcdna3.1-rap1a. |
2020-01-10 |
2023-08-13 |
Not clear |
| Laibo Zhang, Zhoubin Tian, Wei Li, Xianquan Wang, Zhentao Man, Shui Su. Inhibitory effect of quercetin on titanium particle-induced endoplasmic reticulum stress (ERS)-related apoptosis and Bioscience reports. vol 37. issue 4. 2020-01-09. PMID:28760844. |
in this study, raw264.7 cells were pretreated with different concentrations (40, 80, and 160 μmol/l) of que for 30 min and then treated with ti particle (5 mg/ml) for 24 h. cell viability and apoptosis were determined using mtt assay and annexin v-fitc apoptosis detection kit, respectively. |
2020-01-09 |
2023-08-13 |
mouse |
| Chunou Tian, Zifu Li, Lei Zhang, Dongwei Dai, Qinghai Huang, Jianmin Liu, Bo Hon. lncRNA NR_120420 promotes SH-SY5Y cells apoptosis by regulating NF-κB after oxygen and glucose deprivation. Gene. vol 728. 2020-01-09. PMID:31838253. |
cell viability was evaluated with the cell counting kit 8 (cck8) assay, while tunel staining and flow cytometry analysis were performed to determine apoptosis. |
2020-01-09 |
2023-08-13 |
Not clear |
| Ke Li, Fangzheng Zhou, Yu Zhou, Sheng Zhang, Qianwen Li, Zhenyu Li, Li Liu, Gang Wu, Rui Men. Quinalizarin, a specific CK2 inhibitor, can reduce icotinib resistance in human lung adenocarcinoma cell lines. International journal of molecular medicine. vol 44. issue 2. 2019-12-23. PMID:31173177. |
cell apoptosis was detected by flow cytometry using the annexin v‑enhanced green fluorescent protein apoptosis detection kit. |
2019-12-23 |
2023-08-13 |
human |
| Naiyuan Shao, Lian Xue, Rong Wang, Kaiming Luo, Feng Zhi, Qing La. miR-454-3p Is an Exosomal Biomarker and Functions as a Tumor Suppressor in Glioma. Molecular cancer therapeutics. vol 18. issue 2. 2019-11-25. PMID:30413650. |
cell-counting kit 8 (cck-8), wound healing, transwell invasion, apoptosis, and immunofluorescence assays were used to assess the role of mir-454-3p in glioma cancer cells. |
2019-11-25 |
2023-08-13 |
Not clear |
| Hyun-Sook Ki. Extracts of Chrysanthemum zawadskii attenuate oxidative damage to vascular endothelial cells caused by a highly reducing sugar. Cytotechnology. vol 69. issue 6. 2019-11-20. PMID:28608258. |
cell viability was monitored using a cell counting kit, and the induction of apoptosis was evaluated with a cell death kit. |
2019-11-20 |
2023-08-13 |
Not clear |
| Yun Qin, Xicai Tang, Mingxing Li. Tumor-Suppressor Gene NBPF1 Inhibits Invasion and PI3K/mTOR Signaling in Cervical Cancer Cells. Oncology research. vol 23. issue 1. 2019-11-20. PMID:29021016. |
effects of nbpf1 expression on cell invasion ability and cell apoptosis were analyzed using the matrigel method and an annexin v-fitc cell apoptosis kit, respectively. |
2019-11-20 |
2023-08-13 |
human |
| Lei Wang, Weijun Yan, Jing Wan. Silencing MEKK3 attenuates cardiomyocyte injury caused by hypoxia/reoxygenation via the sonic hedgehog pathway. Journal of cellular physiology. 2019-11-20. PMID:30712259. |
cell viability, cell apoptosis, caspase 3/7 activity, and cleaved-caspase 3 expression were tested using a cck-8 assay, cell death detection plus elisa, caspase-glo 3/7 assay kit and western blot analysis, respectively. |
2019-11-20 |
2023-08-13 |
Not clear |
| Anjun Zuo, Peng Zhao, Yu Zheng, Hui Hua, Xingang Wan. Tripterine inhibits proliferation, migration and invasion of breast cancer MDA-MB-231 cells by up-regulating microRNA-15a. Biological chemistry. 2019-11-20. PMID:30913029. |
viability, proliferation, migration, invasion and apoptosis of mda-mb-231 cells were assessed using the cell counting kit-8 (cck-8) assay, brdu incorporation assay, annexin v-fitc/pi apoptosis detection kit and two-chamber transwell assay, respectively. |
2019-11-20 |
2023-08-13 |
Not clear |
| Shanshan Wang, Mingyue Zhu, Qiaoyun Wang, Yuli Hou, Lei Li, Honglei Weng, Yan Zhao, Dexi Chen, Huiguo Ding, Junli Guo, Mengsen L. Alpha-fetoprotein inhibits autophagy to promote malignant behaviour in hepatocellular carcinoma cells by activating PI3K/AKT/mTOR signalling. Cell death & disease. vol 9. issue 10. 2019-11-13. PMID:30301886. |
cell autophagy, apoptosis, proliferation, migration and invasion were analysed with western blotting, co-immunoprecipitation (coip), immunofluorescence, animal models, mtt assays, flow cytometry (fcm), cell counting kit (cck)-8, and scratch and transwell assays. |
2019-11-13 |
2023-08-13 |
Not clear |
| Xiguang Yang, Jingliang He, Bowei Li, Jinqian Zhang, Ke He, Xiaopeng Duan, Rui Huang, Guoan Xian. SWNHs (Single-Wall Carbon Nanohorns) Supervises Endoplasmic Reticulum (ER) Stress in Hepatocellular Carcinoma. Journal of nanoscience and nanotechnology. vol 18. issue 10. 2019-11-11. PMID:29954489. |
and then 38 apoptosis proteins were determined using human apoptosis antibody array kit. |
2019-11-11 |
2023-08-13 |
mouse |
| Fang Yuan, Lu Liu, Yonghong Lei, Yi H. MiRNA-142-3p increases radiosensitivity in human umbilical cord blood mononuclear cells by inhibiting the expression of CD133. Scientific reports. vol 8. issue 1. 2019-10-22. PMID:29618746. |
cck-8 kit was used to detect cell viability, annexin v-fitc/pi cell apoptosis detection kit was used for the detection of apoptotic cells and the brdu assay was performed by flow cytometry. |
2019-10-22 |
2023-08-13 |
human |
| Ding-Yan Lu, Jing Li, Jia Sun, Wei-Na Xue, Bin He, Yong-Jun Li, Yong-Lin Wang, Chang-Hu Lin, Ting Li. [Shenxiong Glucose Injection inhibits H_2O_2-induced apoptosis of H9c2 cells by activating PI3K/AKT pathway]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 44. issue 17. 2019-10-21. PMID:31602952. |
cell viability was detected by mts assay,morphological changes of apoptosis were observed by ao/eb fluorescence staining,apoptosis rate was detected by annexin/pi method,cell expression profile was detected by gene chip technology,the mrna of pik3 ca,bcl-2,bax,caspase-3 and gapdh were detected by qrt-pcr,the protein expression levels of pik3 ca,akt,p-akt,bcl-2,bax and caspase-3 were detected by western blot,and the contents of ldh and mda were detected by kit. |
2019-10-21 |
2023-08-13 |
Not clear |
| Yunjie Zhou, Huichao Zhang, Zhixia Su. [Effect of miR-873 on cardiomyocyte apoptosis induced by hypoxia reoxygenation and its mechanism]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 44. issue 8. 2019-10-17. PMID:31570671. |
cell apoptosis elisa kit and cysteine-containing, aspartate-specific proteases-3 (caspase-3) activity kit was used to detect cell apoptosis and caspase-3 activity, respectively. |
2019-10-17 |
2023-08-13 |
mouse |
| Wen-Hu Liu, Jiang-Bei Yuan, Fan Zhang, Jin-Xia Chan. [Curcumin inhibits proliferation,migration and invasion of gastric cancer cells via Wnt3a/β-catenin/EMT signaling pathway]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 44. issue 14. 2019-10-16. PMID:31602860. |
the migration and invasiveness of cells were determined by wound healing and transwell assays,the apoptosis rate was assessed by flow cytometry,the expression of n-cadherin,e-cadherin,snail1,wnt3 a,p-β-catenin,p-lrp6,bcl-2 and bax were detected by western blot,and the enzymatic activity of caspase-3,caspase-8 and caspase-9 was evaluated via caspase kit. |
2019-10-16 |
2023-08-13 |
human |
| Tao Yao, Dongqing Zha, Ping Gao, Hua Shui, Xiaoyan W. MiR-874 alleviates renal injury and inflammatory response in diabetic nephropathy through targeting toll-like receptor-4. Journal of cellular physiology. vol 234. issue 1. 2019-10-02. PMID:30171701. |
the cell counting kit (cck-8) assay and 5-ethynyl-2'-deoxyuridine (edu) assay demonstrated that glucose simulation significantly inhibited podocyte proliferation and induced cell apoptosis, which can be reversed by mir-874 mimics significantly. |
2019-10-02 |
2023-08-13 |
mouse |
| Jiping Zhu, Jingjing Li, Xiaomei Wang, Xiaoting Feng, Yi L. Nonstructural Protein NP1 of Human Bocavirus 1 suppresses the growth of A549 cell by promoting autophagy. The new microbiologica. vol 42. issue 3. 2019-09-20. PMID:31157401. |
the apoptosis of a549 was evaluated by apoptosis detection kit and expression of caspase3. |
2019-09-20 |
2023-08-13 |
human |
| Shan Yang, Peng Wu, Jianwen Xiao, Li Jian. Overexpression of COX6B1 protects against I/R‑induced neuronal injury in rat hippocampal neurons. Molecular medicine reports. vol 19. issue 6. 2019-09-09. PMID:31059068. |
cell viability was assessed using a cell counting kit, and the levels of apoptosis and cytosolic ca2+ were analyzed by flow cytometry. |
2019-09-09 |
2023-08-13 |
rat |
| Hamid Bakhshi Aliabad, Soudeh Khanamani Falahati-Pour, Hadis Ahmadirad, Maryam Mohamadi, Mohammad Reza Hajizadeh, Mehdi Mahmood. Vanadium complex: an appropriate candidate for killing hepatocellular carcinoma cancerous cells. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. vol 31. issue 6. 2019-09-03. PMID:30255365. |
the early apoptosis and necrosis/late apoptosis were determined by means of annexin v/pi apoptosis detection kit. |
2019-09-03 |
2023-08-13 |
human |