| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tingting Wang, Lin Zhu, Hongling Liu, Guoyi Yu, Yunliang Gu. Picroside II Protects SH-SY5Y Cells From Autophagy and Apoptosis Following Oxygen Glucose Deprivation/Reoxygen Injury by Inhibiting JNK Signal Pathway. Anatomical record (Hoboken, N.J. : 2007). vol 302. issue 12. 2020-09-11. PMID:31251836. |
apoptoic cells were detected by annexin v-fitc/pi apoptosis detection kit. |
2020-09-11 |
2023-08-13 |
Not clear |
| Ying Cheng, Tongjie Cheng, Yuqing Zhao, Yi Q. HMGA1 exacerbates tumor progression by activating miR-222 through PI3K/Akt/MMP-9 signaling pathway in uveal melanoma. Cellular signalling. vol 63. 2020-09-08. PMID:31394192. |
moreover, the proliferation and migration of um cells significantly increased in the mir-222 mimics group and decreased in the mir-222 inhibitor group detected by the annexin v-fitc apoptosis detection kit, cck-8 and scratch wound-healing. |
2020-09-08 |
2023-08-13 |
mouse |
| Tianyu Cheng, Mudong Xu, Bai Qin, Jian Wu, Yuanyuan Tu, Lihua Kang, Yong Wang, Huaijin Gua. lncRNA H19 contributes to oxidative damage repair in the early age-related cataract by regulating miR-29a/TDG axis. Journal of cellular and molecular medicine. vol 23. issue 9. 2020-09-04. PMID:31282110. |
human lens epithelial cells (hlecs) were exposed to ultraviolet irradiation; and 8-ohdg elisa, cell counting kit 8 (cck8), edu, flow cytometry and tunel assays were used to detect dna damage, cell viability, proliferation and apoptosis. |
2020-09-04 |
2023-08-13 |
human |
| Junshu Li, Xiaolan Su, Lei Dai, Na Chen, Chao Fang, Zhexu Dong, Jiamei Fu, Yan Yu, Wenshuang Wang, Hantao Zhang, Huiling Wang, Yanhong Ji, Yi Liu, Lin Cheng, Gang Shi, Shuang Zhang, Yang Yang, Hongxin Den. Temporal DNA methylation pattern and targeted therapy in colitis-associated cancer. Carcinogenesis. vol 41. issue 2. 2020-08-31. PMID:31802101. |
genes that were downregulated and hypermethylated during cac, including hub-genes bad and inositol polyphosphate phosphatase-like 1 (inppl1), were involved in mapk signaling pathways, kit receptor signaling pathways, apoptosis and egf/egfr signaling pathways. |
2020-08-31 |
2023-08-13 |
mouse |
| Yanhui Yu, Panpan Zhao, Lili Cao, Pengtao Gong, Shuxian Yuan, Xinhua Yao, Yanbing Guo, Hang Dong, Weina Jian. A Novel Anti-Microbial Peptide from Pseudomonas, REDLK Induced Growth Inhibition of Leishmania tarentolae Promastigote In Vitro. The Korean journal of parasitology. vol 58. issue 2. 2020-08-24. PMID:32418386. |
cellular apoptosis was observed using the annexin v-fitc/pi apoptosis detection kit, mitochondrial membrane potential assay kit and flow cytometry. |
2020-08-24 |
2023-08-13 |
Not clear |
| Jacqueline Nolan, Dmitry A Nedosekin, Ekaterina I Galanzha, Vladimir P Zharo. Detection of Apoptotic Circulating Tumor Cells Using in vivo Fluorescence Flow Cytometry. Cytometry. Part A : the journal of the International Society for Analytical Cytology. vol 95. issue 6. 2020-08-17. PMID:30508273. |
the proof of concept was demonstrated with two-color fluorescence flow cytometry (ffc) using breast cancer cells mda-mb-231 expressing green fluorescein protein (gfp), staurosporine as an activator of apoptosis, annexin-v apoptotic kit with orange dye color, and a mouse model. |
2020-08-17 |
2023-08-13 |
mouse |
| Arumugam Ponnan, Arunkumar Kulanthaiyesu, Murugan Marudhamuthu, Kamalakkannan Palanisamy, Murugan Kadarkara. Protective effects of fucoidan against 4-nitroquinolin-1-oxide provoked genetic damage in mouse bone marrow cells. Environmental science and pollution research international. vol 27. issue 25. 2020-08-07. PMID:32504434. |
the 4-nqo caused genetic damages in the form of chromosome/chromatic breakage was estimated by micronuclei assay whereas apoptosis by annexin-v fitc kit and dna damage by comet assay kit. |
2020-08-07 |
2023-08-13 |
mouse |
| Xiaobao Fan, Zhenjiang Li, Xiaoming Wang, Jing Wang, Zhiming Ha. Silencing of KPNA2 inhibits high glucose-induced podocyte injury via inactivation of mTORC1/p70S6K signaling pathway. Biochemical and biophysical research communications. vol 521. issue 4. 2020-07-27. PMID:31727365. |
the cell viability was tested by cck-8 kit, the apoptosis was measured using flow cytometry assay, the apoptotic and the autophagy related genes was detected by western blot. |
2020-07-27 |
2023-08-13 |
Not clear |
| Xue-Qiang Zhang, Li-Hong Song, She-Jun Feng, Xiao-Min Da. LncRNA FGD5-AS1 acts as a competing endogenous RNA for miRNA-223 to lessen oxygen-glucose deprivation and simulated reperfusion (OGD/R)-induced neurons injury. Folia neuropathologica. vol 57. issue 4. 2020-07-22. PMID:32337949. |
cell counting kit 8 (cck8) and flow cytometry assays were used to evaluate the proliferation and apoptosis of neurons. |
2020-07-22 |
2023-08-13 |
rat |
| Fatemeh Masjedi, Sara Keshtgar, Fatemeh Zal, Tahereh Talaei-Khozani, Soodabeh Sameti, Sara Fallahi, Marjane Kazeron. Effects of vitamin D on steroidogenesis, reactive oxygen species production, and enzymatic antioxidant defense in human granulosa cells of normal and polycystic ovaries. The Journal of steroid biochemistry and molecular biology. vol 197. 2020-07-06. PMID:31705961. |
cell viability and apoptosis were detected by annexin-v/propidium iodide detection kit. |
2020-07-06 |
2023-08-13 |
human |
| Lei Li, Xin Peng, Lichun Guo, Yuhan Zhao, Qinghong Chen. Sepsis causes heart injury through endoplasmic reticulum stress-mediated apoptosis signaling pathway. International journal of clinical and experimental pathology. vol 13. issue 5. 2020-06-11. PMID:32509067. |
in this research, a rat model of sepsis was set up by cecal ligation and puncture (clp); serum myocardial enzyme levels were measured using an automated biochemical analyzer, inflammatory cytokine levels were measured by elisa kit, and cardiac histology and cardiomyocyte apoptosis were measured by hematoxylin and eosin (h&e) staining and terminal deoxynucleotidyl transferase dutp nick end labeling (tunel) assay to assess the extent of myocardial damage. |
2020-06-11 |
2023-08-13 |
rat |
| Xin Zhu, Xiaolan L. MiR-423-5p inhibition alleviates cardiomyocyte apoptosis and mitochondrial dysfunction caused by hypoxia/reoxygenation through activation of the wnt/β-catenin signaling pathway via targeting MYBL2. Journal of cellular physiology. vol 234. issue 12. 2020-06-09. PMID:31074036. |
cell apoptosis rate, caspase 3/7 activities, bax and cleaved-caspase 3 (c-caspase 3) protein levels were assayed by flow cytometry, caspase-glo 3/7 assay kit, western blot analysis, respectively. |
2020-06-09 |
2023-08-13 |
Not clear |
| Yang Xia, Ke Wei, Feng-Ming Yang, Liu-Qing Hu, Chun-Feng Pan, Xiang-Long Pan, Wei-Bing Wu, Jun Wang, Wei Wen, Zhi-Cheng He, Jing Xu, Xin-Feng Xu, Quan Zhu, Liang Che. miR-1260b, mediated by YY1, activates KIT signaling by targeting SOCS6 to regulate cell proliferation and apoptosis in NSCLC. Cell death & disease. vol 10. issue 2. 2020-06-04. PMID:30737371. |
mir-1260b, mediated by yy1, activates kit signaling by targeting socs6 to regulate cell proliferation and apoptosis in nsclc. |
2020-06-04 |
2023-08-13 |
Not clear |
| Yang Xia, Ke Wei, Feng-Ming Yang, Liu-Qing Hu, Chun-Feng Pan, Xiang-Long Pan, Wei-Bing Wu, Jun Wang, Wei Wen, Zhi-Cheng He, Jing Xu, Xin-Feng Xu, Quan Zhu, Liang Che. miR-1260b, mediated by YY1, activates KIT signaling by targeting SOCS6 to regulate cell proliferation and apoptosis in NSCLC. Cell death & disease. vol 10. issue 2. 2020-06-04. PMID:30737371. |
this study is the first to illustrate that mir-1260b, mediated by yy1, activates kit signaling by targeting socs6 to regulate nsclc cell proliferation and apoptosis, and is a potential biomarker and therapeutic target for nsclc. |
2020-06-04 |
2023-08-13 |
Not clear |
| Jingying Liu, Juanjuan Wang, Yuzhen Ning, Fengying Che. The inhibition of miR‑101a‑3p alleviates H/R injury in H9C2 cells by regulating the JAK2/STAT3 pathway. Molecular medicine reports. vol 21. issue 1. 2020-06-03. PMID:31746349. |
cell viability and apoptosis were determined by cell counting kit‑8 assays and flow cytometry using a cell apoptosis kit, respectively. |
2020-06-03 |
2023-08-13 |
Not clear |
| Zaiqing Zhang, Gongzeng Luo, Chuandong Yu, Guisheng Yu, Rui Jiang, Xuefeng Sh. MicroRNA-493-5p inhibits proliferation and metastasis of osteosarcoma cells by targeting Kruppel-like factor 5. Journal of cellular physiology. vol 234. issue 8. 2020-05-26. PMID:30773645. |
then, the effects of mir-493-5p overexpression (or suppression) on osteosarcoma cell viability, migration, invasion, and apoptosis, as well as kruppel-like factor 5 (klf5) expression, were assessed using the cell counting kit-8 assay, two-chamber transwell assay, annexin v-fitc/pi apoptosis detection kit, qrt-pcr, and western blotting, respectively. |
2020-05-26 |
2023-08-13 |
Not clear |
| Wenbo Yuan, Rui Zhou, Jingzi Wang, Jie Han, Xiao Yang, Hao Yu, Hongcheng Lu, Xiaolei Zhang, Pengchao Li, Jun Tao, Jifu Wei, Qiang Lu, Haiwei Yang, Min G. Circular RNA Cdr1as sensitizes bladder cancer to cisplatin by upregulating APAF1 expression through miR-1270 inhibition. Molecular oncology. vol 13. issue 7. 2020-05-11. PMID:31131537. |
the abilities of cdr1as and its downstream regulatory molecules to induce apoptosis and promote cisplatin-induced chemosensitivity of bladder cancer cells were determined by flow cytometry and cell counting kit. |
2020-05-11 |
2023-08-13 |
mouse |
| Fengwei Nan, Guibo Sun, Weijie Xie, Tianyuan Ye, Xiao Sun, Ping Zhou, Xi Dong, Jiafu Sun, Xiaobo Sun, Mengren Zhan. Ginsenoside Rb1 mitigates oxidative stress and apoptosis induced by methylglyoxal in SH-SY5Y cells via the PI3K/Akt pathway. Molecular and cellular probes. vol 48. 2020-05-11. PMID:31629029. |
cell apoptosis was assessed using hoechst 33342/propidium iodide (pi) staining and an annexin-v/pi kit. |
2020-05-11 |
2023-08-13 |
Not clear |
| Yiwei Zhang, Juan Yan, Xiaowei Pa. miR-141-3p affects apoptosis and migration of endometrial stromal cells by targeting KLF-12. Pflugers Archiv : European journal of physiology. vol 471. issue 8. 2020-04-30. PMID:31129698. |
cell apoptosis was evaluated using a cell death detection elisa plus kit. |
2020-04-30 |
2023-08-13 |
Not clear |
| Xueyuan Yu, Xiangyu Liu, Rui Wang, Lu Wan. Long non-coding RNA NEAT1 promotes the progression of hemangioma via the miR-361-5p/VEGFA pathway. Biochemical and biophysical research communications. vol 512. issue 4. 2020-04-09. PMID:30928097. |
the role and mechanism of neat1 on the proliferation, migration and apoptosis of hemangioma endothelial cells (hemecs) were analyzed by cell counting kit (cck)-8, transwell, flow cytometry, caspase-3 activity, dual-luciferase assay, rna immunoprecipitation, biotin-labeled mir-361-5p pulldown assay and western blot by gain- and loss-of-functions. |
2020-04-09 |
2023-08-13 |
Not clear |