| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xue Wu, Yiqun Yuan, Ruiqi Ma, Binbin Xu, Rui Zhan. lncRNA SNHG7 affects malignant tumor behaviors through downregulation of EZH2 in uveal melanoma cell lines. Oncology letters. vol 19. issue 2. 2020-09-28. PMID:32002036. |
an apoptosis assay was performed using the annexin-v-fluorescein isothiocyanate apoptosis detection kit. |
2020-09-28 |
2023-08-13 |
Not clear |
| Rujuan Xin, Zhongjian Chen, Jin Fu, Fuming Shen, Quangang Zhu, Fang Huan. Xanomeline Protects Cortical Cells From Oxygen-Glucose Deprivation via Inhibiting Oxidative Stress and Apoptosis. Frontiers in physiology. vol 11. 2020-09-28. PMID:32595528. |
the effects of xanomeline on apoptosis, cell viability, lactate dehydrogenase (ldh) levels, and reactive oxygen species (ros) were determined using an annexin v apoptosis detection kit, a non-radioactive cell counting kit-8 (cck-8) assay, colorimetric ldh cytotoxicity assay kit, and a dichloro-dihydro-fluorescein diacetate (dcfh-da) assay, respectively, and the expressions of sirtuin 1, haem oxygenase-1 (ho-1), b-cell lymphoma 2 (bcl-2), poly adp-ribose polymerase (parp), and hypoxia-inducible factor α (hif-1α) as well as the level of phosphorylated kinase b (p-akt) were determined by western blotting. |
2020-09-28 |
2023-08-13 |
rat |
| Shuaishuai Hu, Yang Chen, Bohao Zhao, Naisu Yang, Shi Chen, Jinyu Shen, Guolian Bao, Xinsheng W. KIT is involved in melanocyte proliferation, apoptosis and melanogenesis in the Rex Rabbit. PeerJ. vol 8. 2020-09-28. PMID:32596061. |
kit is involved in melanocyte proliferation, apoptosis and melanogenesis in the rex rabbit. |
2020-09-28 |
2023-08-13 |
rabbit |
| Shuaishuai Hu, Yang Chen, Bohao Zhao, Naisu Yang, Shi Chen, Jinyu Shen, Guolian Bao, Xinsheng W. KIT is involved in melanocyte proliferation, apoptosis and melanogenesis in the Rex Rabbit. PeerJ. vol 8. 2020-09-28. PMID:32596061. |
however, the effect of kit on the proliferation and apoptosis of melanocytes and melanogenesis has not been clarified. |
2020-09-28 |
2023-08-13 |
rabbit |
| Li Yan, Lian-Zhao Wang, Ran Xiao, Rui Cao, Bo Pan, Xiao-Yan Lv, Hu Jiao, Qiang Zhuang, Xue-Jian Sun, Yuan-Bo Li. Inhibition of microRNA-21-5p reduces keloid fibroblast autophagy and migration by targeting PTEN after electron beam irradiation. Laboratory investigation; a journal of technical methods and pathology. vol 100. issue 3. 2020-09-25. PMID:31558773. |
autophagy and apoptosis were tested in keloid fibroblasts after eb irradiation or transfection with an mir-21-5p inhibitor using electron microscopy, a cyto-id green autophagy detection kit, and an annexin v pe apoptosis detection kit. |
2020-09-25 |
2023-08-13 |
Not clear |
| Naoko Adachi, Ippei Kanazawa, Ken-Ichiro Tanaka, Ayumu Takeno, Masakazu Notsu, Sayuri Tanaka, Toshitsugu Sugimot. Insulin-Like Growth Factor-I Protects Against the Detrimental Effects of Advanced Glycation End Products and High Glucose in Myoblastic C2C12 Cells. Calcified tissue international. vol 105. issue 1. 2020-09-24. PMID:30809689. |
real-time pcr and western blot were performed to investigate mrna and protein expressions, and apoptosis was examined by using a dna fragment detection elisa kit. |
2020-09-24 |
2023-08-13 |
mouse |
| Jaw Long Sun, A M Abd El-Aty, Ji Hoon Jeong, Tae Woo Jun. Ginsenoside Rb2 Ameliorates LPS-Induced Inflammation and ER Stress in HUVECs and THP-1 Cells via the AMPK-Mediated Pathway. The American journal of Chinese medicine. vol 48. issue 4. 2020-09-17. PMID:32431178. |
concentrations of tumor necrosis factor alpha (tnf[formula: see text]) and monocyte chemoattractant protein-1 (mcp-1) in culture media were assessed by enzyme-linked immunosorbent assay (elisa) and apoptosis was evaluated by a cell viability assay and a caspase-3 activity measurement kit. |
2020-09-17 |
2023-08-13 |
Not clear |
| Guangming Song, Ling Tian, Yi Cheng, Jinshan Liu, Kun Wang, Shuai Li, Tianhua L. Antitumor activity of sevoflurane in HCC cell line is mediated by miR-29a-induced suppression of Dnmt3a. Journal of cellular biochemistry. vol 120. issue 10. 2020-09-14. PMID:31190353. |
after transfection and stimulation with sevo, biological activities of huh7 and hepg2 cells were evaluated using the cell counting kit-8, annexin v-fluorescein isothiocyanate apoptosis detection kit, 24-well cell migration assay kit, and tumor invasion 24-well plates. |
2020-09-14 |
2023-08-13 |
Not clear |
| Tingting Wang, Lin Zhu, Hongling Liu, Guoyi Yu, Yunliang Gu. Picroside II Protects SH-SY5Y Cells From Autophagy and Apoptosis Following Oxygen Glucose Deprivation/Reoxygen Injury by Inhibiting JNK Signal Pathway. Anatomical record (Hoboken, N.J. : 2007). vol 302. issue 12. 2020-09-11. PMID:31251836. |
apoptoic cells were detected by annexin v-fitc/pi apoptosis detection kit. |
2020-09-11 |
2023-08-13 |
Not clear |
| Ying Cheng, Tongjie Cheng, Yuqing Zhao, Yi Q. HMGA1 exacerbates tumor progression by activating miR-222 through PI3K/Akt/MMP-9 signaling pathway in uveal melanoma. Cellular signalling. vol 63. 2020-09-08. PMID:31394192. |
moreover, the proliferation and migration of um cells significantly increased in the mir-222 mimics group and decreased in the mir-222 inhibitor group detected by the annexin v-fitc apoptosis detection kit, cck-8 and scratch wound-healing. |
2020-09-08 |
2023-08-13 |
mouse |
| Tianyu Cheng, Mudong Xu, Bai Qin, Jian Wu, Yuanyuan Tu, Lihua Kang, Yong Wang, Huaijin Gua. lncRNA H19 contributes to oxidative damage repair in the early age-related cataract by regulating miR-29a/TDG axis. Journal of cellular and molecular medicine. vol 23. issue 9. 2020-09-04. PMID:31282110. |
human lens epithelial cells (hlecs) were exposed to ultraviolet irradiation; and 8-ohdg elisa, cell counting kit 8 (cck8), edu, flow cytometry and tunel assays were used to detect dna damage, cell viability, proliferation and apoptosis. |
2020-09-04 |
2023-08-13 |
human |
| Junshu Li, Xiaolan Su, Lei Dai, Na Chen, Chao Fang, Zhexu Dong, Jiamei Fu, Yan Yu, Wenshuang Wang, Hantao Zhang, Huiling Wang, Yanhong Ji, Yi Liu, Lin Cheng, Gang Shi, Shuang Zhang, Yang Yang, Hongxin Den. Temporal DNA methylation pattern and targeted therapy in colitis-associated cancer. Carcinogenesis. vol 41. issue 2. 2020-08-31. PMID:31802101. |
genes that were downregulated and hypermethylated during cac, including hub-genes bad and inositol polyphosphate phosphatase-like 1 (inppl1), were involved in mapk signaling pathways, kit receptor signaling pathways, apoptosis and egf/egfr signaling pathways. |
2020-08-31 |
2023-08-13 |
mouse |
| Yanhui Yu, Panpan Zhao, Lili Cao, Pengtao Gong, Shuxian Yuan, Xinhua Yao, Yanbing Guo, Hang Dong, Weina Jian. A Novel Anti-Microbial Peptide from Pseudomonas, REDLK Induced Growth Inhibition of Leishmania tarentolae Promastigote In Vitro. The Korean journal of parasitology. vol 58. issue 2. 2020-08-24. PMID:32418386. |
cellular apoptosis was observed using the annexin v-fitc/pi apoptosis detection kit, mitochondrial membrane potential assay kit and flow cytometry. |
2020-08-24 |
2023-08-13 |
Not clear |
| Jacqueline Nolan, Dmitry A Nedosekin, Ekaterina I Galanzha, Vladimir P Zharo. Detection of Apoptotic Circulating Tumor Cells Using in vivo Fluorescence Flow Cytometry. Cytometry. Part A : the journal of the International Society for Analytical Cytology. vol 95. issue 6. 2020-08-17. PMID:30508273. |
the proof of concept was demonstrated with two-color fluorescence flow cytometry (ffc) using breast cancer cells mda-mb-231 expressing green fluorescein protein (gfp), staurosporine as an activator of apoptosis, annexin-v apoptotic kit with orange dye color, and a mouse model. |
2020-08-17 |
2023-08-13 |
mouse |
| Arumugam Ponnan, Arunkumar Kulanthaiyesu, Murugan Marudhamuthu, Kamalakkannan Palanisamy, Murugan Kadarkara. Protective effects of fucoidan against 4-nitroquinolin-1-oxide provoked genetic damage in mouse bone marrow cells. Environmental science and pollution research international. vol 27. issue 25. 2020-08-07. PMID:32504434. |
the 4-nqo caused genetic damages in the form of chromosome/chromatic breakage was estimated by micronuclei assay whereas apoptosis by annexin-v fitc kit and dna damage by comet assay kit. |
2020-08-07 |
2023-08-13 |
mouse |
| Xiaobao Fan, Zhenjiang Li, Xiaoming Wang, Jing Wang, Zhiming Ha. Silencing of KPNA2 inhibits high glucose-induced podocyte injury via inactivation of mTORC1/p70S6K signaling pathway. Biochemical and biophysical research communications. vol 521. issue 4. 2020-07-27. PMID:31727365. |
the cell viability was tested by cck-8 kit, the apoptosis was measured using flow cytometry assay, the apoptotic and the autophagy related genes was detected by western blot. |
2020-07-27 |
2023-08-13 |
Not clear |
| Xue-Qiang Zhang, Li-Hong Song, She-Jun Feng, Xiao-Min Da. LncRNA FGD5-AS1 acts as a competing endogenous RNA for miRNA-223 to lessen oxygen-glucose deprivation and simulated reperfusion (OGD/R)-induced neurons injury. Folia neuropathologica. vol 57. issue 4. 2020-07-22. PMID:32337949. |
cell counting kit 8 (cck8) and flow cytometry assays were used to evaluate the proliferation and apoptosis of neurons. |
2020-07-22 |
2023-08-13 |
rat |
| Fatemeh Masjedi, Sara Keshtgar, Fatemeh Zal, Tahereh Talaei-Khozani, Soodabeh Sameti, Sara Fallahi, Marjane Kazeron. Effects of vitamin D on steroidogenesis, reactive oxygen species production, and enzymatic antioxidant defense in human granulosa cells of normal and polycystic ovaries. The Journal of steroid biochemistry and molecular biology. vol 197. 2020-07-06. PMID:31705961. |
cell viability and apoptosis were detected by annexin-v/propidium iodide detection kit. |
2020-07-06 |
2023-08-13 |
human |
| Lei Li, Xin Peng, Lichun Guo, Yuhan Zhao, Qinghong Chen. Sepsis causes heart injury through endoplasmic reticulum stress-mediated apoptosis signaling pathway. International journal of clinical and experimental pathology. vol 13. issue 5. 2020-06-11. PMID:32509067. |
in this research, a rat model of sepsis was set up by cecal ligation and puncture (clp); serum myocardial enzyme levels were measured using an automated biochemical analyzer, inflammatory cytokine levels were measured by elisa kit, and cardiac histology and cardiomyocyte apoptosis were measured by hematoxylin and eosin (h&e) staining and terminal deoxynucleotidyl transferase dutp nick end labeling (tunel) assay to assess the extent of myocardial damage. |
2020-06-11 |
2023-08-13 |
rat |
| Xin Zhu, Xiaolan L. MiR-423-5p inhibition alleviates cardiomyocyte apoptosis and mitochondrial dysfunction caused by hypoxia/reoxygenation through activation of the wnt/β-catenin signaling pathway via targeting MYBL2. Journal of cellular physiology. vol 234. issue 12. 2020-06-09. PMID:31074036. |
cell apoptosis rate, caspase 3/7 activities, bax and cleaved-caspase 3 (c-caspase 3) protein levels were assayed by flow cytometry, caspase-glo 3/7 assay kit, western blot analysis, respectively. |
2020-06-09 |
2023-08-13 |
Not clear |