| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Weipeng Zhao, Xichuan Li, Jun Wang, Chen Wang, Yongsheng Jia, Shunzong Yuan, Yong Huang, Yehui Shi, Zhongsheng Ton. Decreasing Eukaryotic Initiation Factor 3C (EIF3C) Suppresses Proliferation and Stimulates Apoptosis in Breast Cancer Cell Lines Through Mammalian Target of Rapamycin (mTOR) Pathway. Medical science monitor : international medical journal of experimental and clinical research. vol 23. 2017-12-15. PMID:28854163. |
we utilized the stress and apoptosis signaling antibody array kit, while p-erk1/2, p-akt, p-smad2, p-p38 mapk, cleaved caspase-3, and cleaved caspase-7 were explored between eif3c-sirna and controls. |
2017-12-15 |
2023-08-13 |
human |
| Jun Li, Siyang Ren, Yongjian Liu, Zhigang Lian, Bin Dong, Yiqun Yao, Yinghui X. Knockdown of NUPR1 inhibits the proliferation of glioblastoma cells via ERK1/2, p38 MAPK and caspase-3. Journal of neuro-oncology. vol 132. issue 1. 2017-12-13. PMID:28000106. |
facs analysis and a signaling antibody array kit were used to detect the mechanism by which nupr1 modulates cell cycle and apoptosis activities in glioblastoma cells. |
2017-12-13 |
2023-08-13 |
human |
| Yu An, Dan-Di Zhang, Huan-Ling Yu, Wei-Wei Ma, Yan-Hui Lu, Quan-Ri Liu, Rong Xia. 27-Hydroxycholesterol regulates cholesterol synthesis and transport in C6 glioma cells. Neurotoxicology. vol 59. 2017-11-22. PMID:28167099. |
c6 cells were treated with 5, 10 and 20μm 27-ohc for 24h and the cell viability and apoptosis, the cholesterol levels and metabolism-related mediators, genes and proteins were subsequently assessed using cell-counting kit (cck)-8, amplex red, elisa, real-time pcr and western blot, respectively. |
2017-11-22 |
2023-08-13 |
Not clear |
| Oluwatosin Adaramoye, Bettina Erguen, Bianca Nitzsche, Michael Höpfner, Klaus Jung, Anja Rabie. Punicalagin, a polyphenol from pomegranate fruit, induces growth inhibition and apoptosis in human PC-3 and LNCaP cells. Chemico-biological interactions. vol 274. 2017-09-05. PMID:28709945. |
antiangiogenic effects were measured using cam assay, while apoptosis was assessed by dna fragmentation, enrichment factor by cell death detection elisa kit and expressions of caspases-3 and -8. |
2017-09-05 |
2023-08-13 |
human |
| Tsuyoshi Takahashi, Asmaa Elzawahry, Sachiyo Mimaki, Eisaku Furukawa, Rie Nakatsuka, Hiromi Nakamura, Takahiko Nishigaki, Satoshi Serada, Tetsuji Naka, Seiichi Hirota, Tatsuhiro Shibata, Katsuya Tsuchihara, Toshirou Nishida, Mamoru Kat. Genomic and transcriptomic analysis of imatinib resistance in gastrointestinal stromal tumors. Genes, chromosomes & cancer. vol 56. issue 4. 2017-07-21. PMID:27997714. |
pre-existing cancer cells with genetic alterations promoting apoptosis resistance may serve as a basis whereby cancer cells with critical mutations, such as secondary kit mutations, can establish full imatinib resistance. |
2017-07-21 |
2023-08-13 |
Not clear |
| Jie Wen, Yan-Kun Zhao, Yan Liu, Jin-Feng Zha. MicroRNA-34a inhibits tumor invasion and metastasis in osteosarcoma partly by effecting C-IAP2 and Bcl-2. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 39. issue 6. 2017-07-18. PMID:28635396. |
the effect of overexpression of mir-34a on osteosarcoma was detected by colony-forming assay, annexin v-fluorescein isothiocyanate apoptosis detection kit i, transwell assay, and animal experiment in vivo. |
2017-07-18 |
2023-08-13 |
Not clear |
| Hong-Zhou Meng, Xiao-Feng Ni, Hai-Ning Yu, Shan-Shan Wang, Sheng-Rong She. Effects of astaxanthin on oxidative stress induced by Cu Journal of Zhejiang University. Science. B. vol 18. issue 2. 2017-07-11. PMID:28124844. |
in the current paper, the effects of ast on viability of prostate cells were investigated by 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (mtt) assay; cell apoptosis and intracellular reactive oxygen species (ros) levels were determined by flow cytometry; the mitochondrial membrane potential (mmp) was measured by fluorospectrophotometer; and activities of malondialdehyde (mda), superoxide dismutase (sod), catalase (cat), and glutathione peroxidase (gsh-px) were evaluated by a detection kit. |
2017-07-11 |
2023-08-13 |
cat |
| Gamze Altıntaş Kazar, Ece Şe. [Investigation of antitumorigenic effects of food-borne non-pathogenic and pathogenic Salmonella enterica strains on MEF, DU145 and HeLa cell lines]. Mikrobiyoloji bulteni. vol 50. issue 3. 2017-06-30. PMID:27525394. |
the cell viability was measured by colorimetric mtt cytotoxicity assay, the percentage of apoptosis was assessed by tali® apoptosis assay-annexin v alexa fluor® 488 kit (invitrogen, molecular probes, life technologies, usa), and the caspase-3 activity was determined by colorimetric protease apotarget™ kit (invitrogen, biosource international, usa). |
2017-06-30 |
2023-08-13 |
mouse |
| Zhaoxia Yu, Aisa Rayile, Xiangyang Zhang, Ying Li, Qiang Zha. Ulinastatin protects against lipopolysaccharide-induced cardiac microvascular endothelial cell dysfunction via downregulation of lncRNA MALAT1 and EZH2 in sepsis. International journal of molecular medicine. vol 39. issue 5. 2017-06-29. PMID:28405676. |
then, cell permeability was evaluated by transendothelial electrical resistance, reactive oxygen species (ros) levels were assessed by 2,7-dichlorofluorescein diacetate, cell apoptosis was detected using annexin v-fitc apoptosis detection kit, and the expression levels of bcl-2, bax, caspase-3, metastasis-associated lung adenocarcinoma transcript 1 (malat1) and ezh2 were detected by rt-qpcr and/or western blotting. |
2017-06-29 |
2023-08-13 |
rat |
| B Tokarz-Deptuła, B Hukowska-Szematowicz, P Niedźwiedzka-Rystwej, A Trzeciak-Ryczek, W Deptuł. Values of apoptosis of lymphocytes and granulocytes in peripheral blood of Polish mixed-breed rabbits in the annual cycle. Polish journal of veterinary sciences. vol 20. issue 1. 2017-06-29. PMID:28525323. |
assessment of apoptosis of lymphocytes and granulocytes was performed using as facscan cytometer by becton dickinson with facsdiva software (usa), using as apofluor® green caspase reagent kit (mp biomedicals, usa) to detect the activity of the total caspase pool 1, 3, 4, 5, 6, 7, 8, 9 in granulocytes and lymphocytes of rabbit peripheral blood. |
2017-06-29 |
2023-08-13 |
rabbit |
| Oluseyi Ogunleye, Bertha Campo, Diana Herrera, Emiel D Post Uiterweer, Kirk P Conra. Relaxin confers cytotrophoblast protection from hypoxia-reoxygenation injury through the phosphatidylinositol 3-kinase-Akt/protein kinase B cell survival pathway. American journal of physiology. Regulatory, integrative and comparative physiology. vol 312. issue 4. 2017-06-27. PMID:28122716. |
the cells were treated with recombinant human relaxin or vehicle and apoptosis and/or necrosis evaluated by terminal deoxynucleotidyl transferase-mediated dutp nick end labeling (tunel), cellevent caspase-3/7 and sytox aadvanced kit, and propidium iodide staining as determined by fluorescence microscopy or flow cytometry. |
2017-06-27 |
2023-08-13 |
human |
| Magdalena Włodarczyk, Jolanta Zdybel, Marek Próchniak, Zbigniew Osiński, Jacek Karamon, Teresa Kłapeć, Tomasz Cence. Viability assessment of Ascaris suum eggs stained with fluorescent dyes using digital colorimetric analysis. Experimental parasitology. vol 178. 2017-06-22. PMID:28479276. |
the best parameters were observed using the annexin v fitc apoptosis detection kit (dasi = 41 and 67). |
2017-06-22 |
2023-08-13 |
Not clear |
| Bin He, Haiying Tao, Ailin Wei, Shiqing Liu, Xiaohai Li, Ren Che. Protection of carboxymethylated chitosan on chondrocytes from nitric oxide-induced apoptosis by regulating phosphatidylinositol 3-kinase/Akt signaling pathway. Biochemical and biophysical research communications. vol 479. issue 2. 2017-06-06. PMID:27644875. |
the cell viability was determined by cell counting kit (cck-8), cell apoptosis was detected by annexin-v/pi double staining assay kit. |
2017-06-06 |
2023-08-13 |
rat |
| D Lin, X Jing, Y Chen, Y Liang, M Lei, S Peng, T Zhou, D Zheng, Z Zeng, X Wu, L Yang, S Xiao, J Liu, E Ta. Rifampicin pre-treatment inhibits the toxicity of rotenone-induced PC12 cells by enhancing sumoylation modification of α-synuclein. Biochemical and biophysical research communications. vol 485. issue 1. 2017-06-06. PMID:28132806. |
the cell viability and apoptosis rate were measured by a cck-8 assay kit and flow cytometry, respectively. |
2017-06-06 |
2023-08-13 |
Not clear |
| Ling Liu, Ping Zhan, Dan Nie, Lingye Fan, Hairui Lin, Lanyang Gao, Xiguang Ma. Intermediate-Conductance-Ca2-Activated K Channel IKCa1 Is Upregulated and Promotes Cell Proliferation in Cervical Cancer Medical science monitor basic research. vol 23. 2017-06-01. PMID:28280257. |
cell apoptosis was assessed using the annexin v-fitc/propidium iodide (pi) double-staining apoptosis detection kit. |
2017-06-01 |
2023-08-13 |
human |
| Zhong-Jun Du, Guan-Qun Cui, Juan Zhang, Xiao-Mei Liu, Zhi-Hu Zhang, Qiang Jia, Jack C Ng, Cheng Peng, Cun-Xiang Bo, Hua Sha. Inhibition of gap junction intercellular communication is involved in silica nanoparticles-induced H9c2 cardiomyocytes apoptosis via the mitochondrial pathway. International journal of nanomedicine. vol 12. 2017-05-22. PMID:28356735. |
the aim of the present study is to determine whether snps-decreased gjic promotes apoptosis in rat cardiomyocytes cell line (h9c2 cells) via the mitochondrial pathway using cck-8 kit, scrape-loading dye transfer technique, annexin v/pi double-staining assays, and western blot analysis. |
2017-05-22 |
2023-08-13 |
rat |
| Li Qiao, Chengshan Xu, Qiang Li, Zhusong Mei, Xinji Li, Hong Cai, Wei Li. Photodynamic therapy activated STAT3 associated pathways: Targeting intrinsic apoptotic pathways to increase PDT efficacy in human squamous carcinoma cells. Photodiagnosis and photodynamic therapy. vol 14. 2017-05-17. PMID:26607555. |
apoptosis and cell viability after pdt were evaluated using annexin v-fitc apoptosis detection kit and mtt assay. |
2017-05-17 |
2023-08-13 |
human |
| Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui L. Interference with Tim-3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis. Molecular medicine reports. vol 15. issue 3. 2017-05-09. PMID:28112366. |
apoptosis was measured using flow cytometry, e‑cadherin and n‑cadherin protein expression were determined using western blotting and a chemicon cell invasion assay kit was used to quantify the invasive capacity of 786‑o and caki‑2 cells. |
2017-05-09 |
2023-08-13 |
Not clear |
| Jin-Guo Li, Qi Hao, Ying-Xue Liu, Peng Li, Peng Li, Xia-Yan Shao, Hua Tian, Yong-Qi Fang, Shu-Tong Ya. [Advanced glycated albumin induces macrophage apoptosis via activating caspase-12 pathway]. Sheng li xue bao : [Acta physiologica Sinica]. vol 68. issue 6. 2017-05-05. PMID:28004067. |
after incubation for 24 h, the cell viability and apoptosis were determined by using mtt assay and tunel detection kit, respectively. |
2017-05-05 |
2023-08-13 |
Not clear |
| Bingqian Xie, Zhijian Xu, Liangning Hu, Gege Chen, Rong Wei, Guang Yang, Bo Li, Gaomei Chang, Xi Sun, Huiqun Wu, Yong Zhang, Bojie Dai, Yi Tao, Jumei Shi, Weiliang Zh. Pterostilbene Inhibits Human Multiple Myeloma Cells via ERK1/2 and JNK Pathway In Vitro and In Vivo. International journal of molecular sciences. vol 17. issue 11. 2017-04-28. PMID:27869675. |
in the present study, we examined the anti-tumor effect of pte on mm cell lines both in vitro and in vivo using the cell counting kit (cck)-8, apoptosis assays, cell cycle analysis, reactive oxygen species (ros) generation, jc-1 mitochondrial membrane potential assay, western blotting and tumor xenograft models. |
2017-04-28 |
2023-08-13 |
mouse |