| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Peijun Tian, Li Ya. Inhibition of MicroRNA-149-5p Induces Apoptosis of Acute Myeloid Leukemia Cell Line THP-1 by Targeting Fas Ligand (FASLG). Medical science monitor : international medical journal of experimental and clinical research. vol 22. 2017-04-28. PMID:28013316. |
aml cell line thp-1 was transfected with mir-149-5p mimic or inhibitor, and then cell apoptosis was determined using the apo percentage assay kit. |
2017-04-28 |
2023-08-13 |
Not clear |
| Lian Jian, Yuan Lu, Shan Lu, Chengzhi L. Chemical Chaperone 4-Phenylbutyric Acid Reduces Cardiac Ischemia/Reperfusion Injury by Alleviating Endoplasmic Reticulum Stress and Oxidative Stress. Medical science monitor : international medical journal of experimental and clinical research. vol 22. 2017-04-24. PMID:28036323. |
a tunel apoptosis assay kit was used to detect apoptosis. |
2017-04-24 |
2023-08-13 |
rat |
| Tie-Jun Liang, Zhong-Mei Zhou, Ying-Qing Cao, Ming-Ze Ma, Xiao-Jun Wang, Kai Jin. Gemcitabine-based polymer-drug conjugate for enhanced anticancer effect in colon cancer. International journal of pharmaceutics. vol 513. issue 1-2. 2017-04-21. PMID:27613255. |
gem-pl formulation exhibited a significantly higher apoptosis of cancer cells (∼25%) when stained using annexin-v/pi kit. |
2017-04-21 |
2023-08-13 |
Not clear |
| Guicheng Li, Tao Li, Yunfeng Li, Shumin Cai, Zhiming Zhang, Zhenhua Zeng, Xingmin Wang, Youguang Gao, Yunfeng Li, Zhongqing Che. Ulinastatin inhibits oxidant-induced endothelial hyperpermeability and apoptotic signaling. International journal of clinical and experimental pathology. vol 7. issue 11. 2017-04-13. PMID:25550770. |
monolayer permeability was determined by transendothelial electrical resistance (ter); mitochondrial release of cytochrome c was determined by enzyme-linked immunosorbent assay; caspase-3 activity was measured by fluorometric assay; adherens junction protein β-catenin was detected by immunofluorescense staining; ratio of cell apoptosis was evaluated by annexin-v/pi double stain assay; mitochondrial membrane potential (Δψm) was determined with jc-1; intracellular atp content was assayed by a commercial kit; bax and bcl-2 expression were estimated by western blotting; intracellular reactive oxygen species (ros) level was measured by dcfh-da. |
2017-04-13 |
2023-08-13 |
Not clear |
| K Wasilewska, Ł Zasiadczyk, L Fraser, M Mogielnicka-Brzozowska, W Korda. The benefits of cooling boar semen in long-term extenders prior to cryopreservation on sperm quality characteristics. Reproduction in domestic animals = Zuchthygiene. vol 51. issue 5. 2017-04-10. PMID:27554400. |
the vybrant apoptosis assay kit was used to analyse the proportions of viable and plasma membrane apoptotic-like changes in spermatozoa. |
2017-04-10 |
2023-08-13 |
Not clear |
| Chang-Long Xu, Bo Zheng, Ji-Hua Pei, Su-Jian Shen, Jian-Zhang Wan. Embelin induces apoptosis of human gastric carcinoma through inhibition of p38 MAPK and NF-κB signaling pathways. Molecular medicine reports. vol 14. issue 1. 2017-04-06. PMID:27175982. |
cellular and nuclear apoptosis were analyzed with an annexin v‑fitc/pi apoptosis detection kit and dapi staining assay, respectively. |
2017-04-06 |
2023-08-13 |
human |
| Hongyan Zhao, Dali Zhao, Huilin Jin, Hongwei Li, Xiaoying Yang, Liwei Zhuang, Tiefu Li. Bufalin reverses intrinsic and acquired drug resistance to cisplatin through the AKT signaling pathway in gastric cancer cells. Molecular medicine reports. vol 14. issue 2. 2017-04-06. PMID:27357249. |
effects of cisplatin and bufalin on gc cells were measured by a cell counting kit, apoptosis was analyzed by flow cytometry, and immunoblotting was used to detect proteins associated with the akt signaling pathway. |
2017-04-06 |
2023-08-13 |
human |
| Xin-Jun Chen, Mian-Yun Wu, Deng-Hui Li, Jin Yo. Apigenin inhibits glioma cell growth through promoting microRNA-16 and suppression of BCL-2 and nuclear factor-κB/MMP‑9. Molecular medicine reports. vol 14. issue 3. 2017-04-06. PMID:27430517. |
cell counting kit‑8 solution and annexin v-fluorescein isothiocyanate/propidium iodide apoptosis detection kit were used to analyze the effect of apigenin on u87 cell viability and apoptotic cell death. |
2017-04-06 |
2023-08-13 |
human |
| Jing Qin, Yongmei Hu. Effects of hydrogen sulfide on the expression of alkaline phosphatase, osteocalcin and collagen type I in human periodontal ligament cells induced by tension force stimulation. Molecular medicine reports. vol 14. issue 4. 2017-04-04. PMID:27573279. |
cell proliferation and apoptosis were determined using a cell counting kit 8 assay and flow cytometric analysis, respectively. |
2017-04-04 |
2023-08-13 |
human |
| Ting Duan, Kai Fan, Shengrong Chen, Qi Yao, Rong Zeng, Zhiwei Hong, Longping Peng, Yong Shao, Bing Ya. Role of peroxiredoxin 2 in H2O2‑induced oxidative stress of primary Leydig cells. Molecular medicine reports. vol 13. issue 6. 2017-03-20. PMID:27082744. |
cell apoptosis was measured using an annexin v fluorescein isothiocyanate/propidium iodide apoptosis detection kit and flow cytometry. |
2017-03-20 |
2023-08-13 |
Not clear |
| Bing Liang, Yanbin Song, Wenling Zheng, Wenli M. miRNA143 Induces K562 Cell Apoptosis Through Downregulating BCR-ABL. Medical science monitor : international medical journal of experimental and clinical research. vol 22. 2017-03-20. PMID:27492780. |
flow cytometry and a caspase-3 activity detection kit were used to test k562 cell apoptosis. |
2017-03-20 |
2023-08-13 |
human |
| Xiaoyu Jiang, Huiren Tao, Cuiting Qiu, Xiaolei Ma, Shan Li, Xian Guo, Anlin Lv, Huan L. Vitamin K2 regression aortic calcification induced by warfarin via Gas6/Axl survival pathway in rats. European journal of pharmacology. vol 786. 2017-03-10. PMID:27212383. |
alizarin red s staining measured aortic calcium depositions; alkaline phosphatase activity in serum was measured by a kit; apoptosis was evaluated by tunel assay; protein expression levels of gas6, axl, phosphorylated akt (p-akt), and bcl-2 were determined by western blotting. |
2017-03-10 |
2023-08-13 |
rat |
| Shaoheng Li, Yuhui Yan, Yanan Jiao, Zhong Gao, Yang Xia, Liang Kong, Yingjia Yao, Zhenyu Tao, Jie Song, Yaping Yan, Guangxian Zhang, Jingxian Yan. Neuroprotective Effect of Osthole on Neuron Synapses in an Alzheimer's Disease Cell Model via Upregulation of MicroRNA-9. Journal of molecular neuroscience : MN. vol 60. issue 1. 2017-03-09. PMID:27394443. |
in this study, the cell counting kit cck-8, apoptosis assay, immunofluorescence analysis, enzyme-linked immunosorbent assay (elisa), quantitative real-time polymerase chain reaction, and western blot assay were used. |
2017-03-09 |
2023-08-13 |
mouse |
| Bin Li, Yu-Min Li, Wen-Ting He, Hao Chen, Hong-Wen Zhu, Tao Liu, Jian-Hua Zhang, Tie-Niu Song, Ya-Li Zho. Knockdown of DDX46 inhibits proliferation and induces apoptosis in esophageal squamous cell carcinoma cells. Oncology reports. vol 36. issue 1. 2017-03-08. PMID:27176873. |
further, the stress and apoptosis signaling antibody array kit was used to detect the changes of signaling molecules in te-1 cells after ddx46 knockdown. |
2017-03-08 |
2023-08-13 |
human |
| Kelly Goulart Lima, Gabriele Catyana Krause, Aline Daniele Schuster, Anderson Velasque Catarina, Bruno Souza Basso, Fernanda Cristina De Mesquita, Leonardo Pedrazza, Elisa Simon Marczak, Bianca Andrade Martha, Fernanda Bordignon Nunes, Eduardo Cremonese Filippi Chiela, Natália Jaeger, Marcos Paulo Thomé, Gabriela Viegas Haute, Henrique Bregolin Dias, Márcio Vinícius Fagundes Donadio, Jarbas Rodrigues De Oliveir. Gallic acid reduces cell growth by induction of apoptosis and reduction of IL-8 in HepG2 cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 84. 2017-02-13. PMID:27810785. |
we observed a significant increase in the percentage of small and regular nuclei (nuclear morphometric analysis assay), a significant induction of apoptosis by annexin v-fitc and pi assay and no interference with the cell cycle using the fitc brdu flow kit. |
2017-02-13 |
2023-08-13 |
human |
| Binglei Shen, Qiqi Pan, Yuwei Yang, Yan Gao, Xin Liu, Wei Li, Yunsheng Han, Xue Yuan, Yongli Qu, Zhihui Zha. miR-224 Affects Mammary Epithelial Cell Apoptosis and Triglyceride Production by Downregulating ACADM and ALDH2 Genes. DNA and cell biology. vol 36. issue 1. 2017-01-31. PMID:27918674. |
furthermore, the triglyceride production and cell apoptosis were detected by triglyceride mensuration reagent kit using flow cytometry. |
2017-01-31 |
2023-08-13 |
Not clear |
| Junwei Zhang, Jiajun Du, Qi Liu, Yi Zhan. Down-regulation of STAT3 expression using vector-based RNA interference promotes apoptosis in Hepatocarcinoma cells. Artificial cells, nanomedicine, and biotechnology. vol 44. issue 5. 2017-01-12. PMID:26134753. |
the apoptotic rate was detected by flow cytometry (fcm) and by staining with the annexin v/propidium iodide (pi) apoptosis detection kit. |
2017-01-12 |
2023-08-13 |
Not clear |
| Pei-Cai Fu, Rong-Hua Tang, Yue Wan, Min-Jie Xie, Wei Wang, Xiang Luo, Zhi-Yuan Y. ROCK inhibition with fasudil promotes early functional recovery of spinal cord injury in rats by enhancing microglia phagocytosis. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 36. issue 1. 2016-12-30. PMID:26838736. |
in this study, western blotting was conducted to detect rock2 expression after the sci; the rock activity assay kit was used for assay of rock pathway activity; microglia morphology was examined using the cd11b antibody; electron microscopy was used to detect microglia phagocytosis; tunel was used to detect tissue cell apoptosis; myelin staining was performed using an antibody against myelin basic protein (mbp); behavioral outcomes were evaluated according to the methods of basso, beattie, and bresnahan (bbb). |
2016-12-30 |
2023-08-13 |
rat |
| Tianze Zhang, Yingying Hu, Jin Ju, Liangyu Hou, Zhange Li, Dan Xiao, Yongchao Li, Jianyu Yao, Chao Wang, Yong Zhang, Linyou Zhan. Downregulation of miR-522 suppresses proliferation and metastasis of non-small cell lung cancer cells by directly targeting DENN/MADD domain containing 2D. Scientific reports. vol 6. 2016-12-26. PMID:26783084. |
furthermore, an mtt assay, 5-ethynyl-2'-deoxyuridine (edu) assay kit and flow cytometry confirmed that the inhibition of mir-522 suppressed nsclc cells proliferation and induced apoptosis. |
2016-12-26 |
2023-08-13 |
human |
| Fan-Dong Meng, Shuai Wang, You-Hong Jiang, Cheng-Guang Su. Antitumor effect of dendritic cells transfected with prostate-specific membrane antigen recombinant adenovirus on prostate cancer: An in vitro study. Molecular medicine reports. vol 13. issue 3. 2016-12-19. PMID:26783185. |
in addition, a pe‑7aad apoptosis and necrosis kit was applied to detect the survival of dcs at different moi values to determine the optimal moi. |
2016-12-19 |
2023-08-13 |
Not clear |