| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jun-Qi Dai, Yi-Gang Huang, Ai-Na H. Dihydromethysticin kavalactone induces apoptosis in osteosarcoma cells through modulation of PI3K/Akt pathway, disruption of mitochondrial membrane potential and inducing cell cycle arrest. International journal of clinical and experimental pathology. vol 8. issue 5. 2016-04-15. PMID:26191127. |
apoptosis induction by dihydromethysticin was demonstrated by fluorescence microscopy, quantitative videomicroscopy and annexin v-fitc apoptosis detection kit. |
2016-04-15 |
2023-08-13 |
human |
| Aline Teixeira Amorim, Lucas Miranda Marques, Angelita Maria Oliveira Gusmão Santos, Hellen Braga Martins, Maysa Santos Barbosa, Izadora Souza Rezende, Ewerton Ferraz Andrade, Guilherme Barreto Campos, Tássia Neves Lobão, Beatriz Araujo Cortez, Telma Alvez Monezi, Glaucia Maria Machado-Santelli, Jorge Timenetsk. Apoptosis in HEp-2 cells infected with Ureaplasma diversum. Biological research. vol 47. 2016-04-11. PMID:25299837. |
the apoptosis was evaluated using pro-apoptotic and anti-apoptotic gene expression, and fitc annexin v/dead cell apoptosis kit. |
2016-04-11 |
2023-08-13 |
Not clear |
| YaSai Yao, Jian Hu, Zan Shen, RuYong Yao, ShiHai Liu, Yong Li, Hui Cong, XinGang Wang, WenSheng Qiu, Lu Yu. MiR-200b expression in breast cancer: a prognostic marker and act on cell proliferation and apoptosis by targeting Sp1. Journal of cellular and molecular medicine. vol 19. issue 4. 2016-04-01. PMID:25639535. |
in vitro, effects of mir-200b on bc cell proliferation, apoptosis and cell cycle distribution were tested by cck-8 kit, flow cytometric analysis respectively. |
2016-04-01 |
2023-08-13 |
human |
| A Förster, S P Grotha, J M Seeger, A Rabenhorst, M Gehring, U Raap, S Létard, P Dubreuil, H Kashkar, H Walczak, A Roers, K Hartman. Activation of KIT modulates the function of tumor necrosis factor-related apoptosis-inducing ligand receptor (TRAIL-R) in mast cells. Allergy. vol 70. issue 7. 2016-03-24. PMID:25833810. |
recent studies reported on the expression of trail-rs and trail-induced apoptosis in cultured human mcs, which depend on stem cell factor (scf)-induced or constitutive kit activation. |
2016-03-24 |
2023-08-13 |
human |
| Wei Tang, Yinong Zhang, Qing Zhang, Qinghua Wang, Zhifeng W. Hydroxycamptothecin-induced apoptotic gene expression profiling by PCR array in human Tenon's capsule fibroblasts. International journal of clinical and experimental pathology. vol 8. issue 3. 2016-03-22. PMID:26045770. |
apoptosis was determined using the annexin v-fitc/pi apoptosis detection kit and apoptotic cells were identified by flow cytometry. |
2016-03-22 |
2023-08-13 |
human |
| Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wan. GDC-0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway. International journal of oncology. vol 46. issue 4. 2016-03-21. PMID:25651778. |
the viability of saos2 cells was determined by mtt assay, the migration of saos2 cells was analyzed by chamber migration assay kit, and the saos2 cell apoptosis was determined by fluorescence-activated cell sorting (facs) and nuclear staining. |
2016-03-21 |
2023-08-13 |
human |
| G Wedeh, S Cerny-Reiterer, G Eisenwort, H Herrmann, K Blatt, E Hadzijusufovic, I Sadovnik, L Müllauer, J Schwaab, T Hoffmann, J E Bradner, D Radia, W R Sperr, G Hoermann, A Reiter, H-P Horny, J Zuber, M Arock, P Valen. Identification of bromodomain-containing protein-4 as a novel marker and epigenetic target in mast cell leukemia. Leukemia. vol 29. issue 11. 2016-02-24. PMID:26055303. |
correspondingly, the brd4-targeting drug jq1 induced dose-dependent growth inhibition and apoptosis in hmc-1 and rosa cells, regardless of the presence or absence of kit d816v. |
2016-02-24 |
2023-08-13 |
human |
| T D Lebedev, P V Spirin, M V Suntsova, A V Ivanova, A A Buzdin, M M Prokofjeva, P M Rubtsov, V S Prassolo. [Receptor tyrosine kinase KIT may regulate expression of genes involved in spontaneous regression of neuroblastoma]. Molekuliarnaia biologiia. vol 49. issue 6. 2016-02-23. PMID:26710790. |
downregulation of kit expression by rna interference in sh-sy5y cells causes suppression of neurotrophin receptor ngfr expression that may promote the loss of sensibility of cells to nerve growth factors, also it causes upregulation of trka receptor expression which can stimulate cell differentiation or apoptosis in ngf dependent manner. |
2016-02-23 |
2023-08-13 |
Not clear |
| A Nikolova, G Momekov, A Bakalova, K Nikolova, D Ivano. Novel Ru(III) Complexes with Some Benzothiazole Derivatives: Synthesis, Physicochemical and Pharmacological Investigations. Drug research. vol 65. issue 6. 2016-02-19. PMID:24992498. |
moreover, the ability of the complexes to trigger apoptosis was evaluated using a commercially available dna-fragmentation elisa kit and the obtained data indicated that their proapoptotic effects well correlate to the mtt-bioassay data. |
2016-02-19 |
2023-08-13 |
human |
| Xiao-yan Xu, Xiao-cui Nie, Hai-ying Ma, Guo-qing Song, Xiao-tong Zhang, Yu-nan Jin, Yan-qiu Y. Flow Cytometry Method Analysis of Apoptosis: No Significant Difference Between EDTA and EDTA-free Trypsin Treatment Procedure. Technology in cancer research & treatment. vol 14. issue 2. 2016-02-17. PMID:24502547. |
although apoptosis assay kit was applied by many companies, the manufacturers were not consistent with whether using trypsin with edta to collect the adherent cells. |
2016-02-17 |
2023-08-12 |
Not clear |
| Liangliang Zhou, Lanping Chen, Jing Wang, Yijun Den. Astragalus polysaccharide improves cardiac function in doxorubicin-induced cardiomyopathy through ROS-p38 signaling. International journal of clinical and experimental medicine. vol 8. issue 11. 2016-02-17. PMID:26885153. |
the effects of dox on rat cardiomyocytes apoptosis by hoechst staining and annexin v-pi staining, while caspase3 activity was determined using an assay kit. |
2016-02-17 |
2023-08-13 |
mouse |
| Jinsong Xiao, Li Liu, Zian Zhong, Cheng Xiao, Junjian Zhan. Mangiferin regulates proliferation and apoptosis in glioma cells by induction of microRNA-15b and inhibition of MMP-9 expression. Oncology reports. vol 33. issue 6. 2016-02-16. PMID:25901555. |
then, cell apoptosis of u87 glioma cells was measured with the annexin v-fitc/propidium iodide (pi) apoptosis detection kit, dapi staining assay and the caspase-3 and caspase-9 activity assay kit. |
2016-02-16 |
2023-08-13 |
Not clear |
| Tian-Jiao Li, Yan-Hong Huang, Xi Chen, Zhou Zhou, Si-Wei Luo, Dan-Dan Feng, Jian-Zhong Han, Zi-Qiang Lu. [Metabotropic glutamate receptor 8 activation promotes the apoptosis of lung carcinoma A549 cells in vitro]. Sheng li xue bao : [Acta physiologica Sinica]. vol 67. issue 5. 2016-02-10. PMID:26490069. |
to observe the effects of mglur8 and mglur4 activation on the growth of a549 cells, the cultured cells were treated with (s)-3,4-dcpg (an agonist of mglur8) and vu0155041 (an agonist of mglur4), respectively, and then the cell viability was analyzed by cck-8 kit, the percentage of dna synthesis was detected by edu incorporation, and the apoptosis of the cells was measured by hoechst 33258 staining and flow cytometry. |
2016-02-10 |
2023-08-13 |
Not clear |
| Xiaoli Zhang, Haiyu Zhang, Qing Gao, Shufang Ji, Lujun Bing, Jing Ha. Sohlh2 inhibits the apoptosis of mouse primordial follicle oocytes via C-kit/PI3K/Akt/Foxo3a signalling pathway. Reproductive biomedicine online. vol 30. issue 5. 2016-02-08. PMID:25773528. |
we previously reported that bone morphogenetic protein 4/drosophila mothers against decapentaplegic protein (bmp4/smad) signalling pathway initiated primordial follicle growth and prevented oocyte apoptosis via up-regulation of sohlh2 and receptor for kit ligand (c-kit). |
2016-02-08 |
2023-08-13 |
mouse |
| Shabnam Abdi, Mojdeh Salehnia, Saman Hosseinkhan. Kit ligand decreases the incidence of apoptosis in cultured vitrified whole mouse ovaries. Reproductive biomedicine online. vol 30. issue 5. 2016-02-08. PMID:25779020. |
kit ligand decreases the incidence of apoptosis in cultured vitrified whole mouse ovaries. |
2016-02-08 |
2023-08-13 |
mouse |
| Shabnam Abdi, Mojdeh Salehnia, Saman Hosseinkhan. Kit ligand decreases the incidence of apoptosis in cultured vitrified whole mouse ovaries. Reproductive biomedicine online. vol 30. issue 5. 2016-02-08. PMID:25779020. |
to investigate the development of follicles and incidence of apoptosis in vitrified cultured mouse ovaries in the presence and absence of kit ligand, 1-week-old mouse ovaries were cultured in the presence or absence of kit ligand for 7 days. |
2016-02-08 |
2023-08-13 |
mouse |
| Xiao-dan Zhang, Yan-nan Yang, Shu-jing Wang, Da-ling Zhu, Li-wei Wang, Jie-jing Sheng, Sha-sha Son. [Effect of puerarin on PI3K/AKT pathway-mediated apoptosis of PASMCs]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 40. issue 15. 2016-02-01. PMID:26677708. |
with the serum starvation group (sd group) as the control group, the mtt colorimetry method, annexin v-fitc apoptosis detection kit and western blot were used to detect pue's effect on apoptosis of rat pasmcs. |
2016-02-01 |
2023-08-13 |
rat |
| N Haas, T Riedt, Z Labbaf, K Baßler, D Gergis, H Fröhlich, I Gütgemann, V Janzen, H Schorl. Kit transduced signals counteract erythroid maturation by MAPK-dependent modulation of erythropoietin signaling and apoptosis induction in mouse fetal liver. Cell death and differentiation. vol 22. issue 5. 2015-12-24. PMID:25323585. |
kit transduced signals counteract erythroid maturation by mapk-dependent modulation of erythropoietin signaling and apoptosis induction in mouse fetal liver. |
2015-12-24 |
2023-08-13 |
mouse |
| N Haas, T Riedt, Z Labbaf, K Baßler, D Gergis, H Fröhlich, I Gütgemann, V Janzen, H Schorl. Kit transduced signals counteract erythroid maturation by MAPK-dependent modulation of erythropoietin signaling and apoptosis induction in mouse fetal liver. Cell death and differentiation. vol 22. issue 5. 2015-12-24. PMID:25323585. |
primary kit(d816v) erythroblasts stimulated to differentiate fail to exit cell cycle and show elevated rates of apoptosis because of insufficient induction of survival factors. |
2015-12-24 |
2023-08-13 |
mouse |
| Alireza Mehdizadeh, Sajjad Pandesh, Ali Shakeri-Zadeh, Seyed Kamran Kamrava, Mojtaba Habib-Agahi, Mohammad Farhadi, Morteza Pishghadam, Amirhossein Ahmadi, Sanam Arami, Yuri Feduti. The effects of folate-conjugated gold nanorods in combination with plasmonic photothermal therapy on mouth epidermal carcinoma cells. Lasers in medical science. vol 29. issue 3. 2015-12-15. PMID:24013622. |
apoptosis was determined by flow cytometry using an annexin v-fluorescein isothiocyanate/propidium iodide apoptosis detection kit. |
2015-12-15 |
2023-08-12 |
Not clear |