Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Erola Ainsua-Enrich, Eva Serrano-Candelas, Damiana Álvarez-Errico, César Picado, Joan Sayós, Juan Rivera, Margarita Martí. The adaptor 3BP2 is required for KIT receptor expression and human mast cell survival. Journal of immunology (Baltimore, Md. : 1950). vol 194. issue 9. 2015-06-30. PMID:25810396. |
unexpectedly, silencing of 3bp2 reduces kit expression in normal humcs as well as in hmc-1 cells where kit is mutated, thus increasing cellular apoptosis and caspase-3/7 activity. |
2015-06-30 |
2023-08-13 |
human |
Fong Ming Koh, Carlos O Lizama, Priscilla Wong, John S Hawkins, Ann C Zovein, Miguel Ramalho-Santo. Emergence of hematopoietic stem and progenitor cells involves a Chd1-dependent increase in total nascent transcription. Proceedings of the National Academy of Sciences of the United States of America. vol 112. issue 14. 2015-06-29. PMID:25831528. |
mutant embryos contain normal numbers of e10.5 intraaortic hematopoietic clusters that express runx1 and kit, but these clusters undergo apoptosis and fail to mature into blood lineages in vivo and in vitro. |
2015-06-29 |
2023-08-13 |
mouse |
Wen-Xiao Xu, Yang Liu, Sheng-Zhi Liu, Yu Zhang, Guo-Fen Qiao, Jinglong Ya. Arsenic trioxide exerts a double effect on osteoblast growth in vitro. Environmental toxicology and pharmacology. vol 38. issue 2. 2015-06-23. PMID:25128771. |
cell survives, apoptosis, collagen, and molecular targets were identified by multiple detecting techniques, including mtt assay, electron microscopy, collagen detecting kit, tunel kit, and western blot in hfob1.19 human osteoblasts cell line. |
2015-06-23 |
2023-08-13 |
human |
Haiying Zhang, Xuejin Su, Li Guo, Lingzhi Zhong, Wenxue Li, Zhen Yue, Xiaotong Wang, Yan Mu, Xinna Li, Ronggui Li, Zonggui Wan. Silencing SATB1 inhibits the malignant phenotype and increases sensitivity of human osteosarcoma U2OS cells to arsenic trioxide. International journal of medical sciences. vol 11. issue 12. 2015-06-22. PMID:25317073. |
cell apoptosis was analyzed by an in situ cell death detection pod kit, based on terminal deoxynucleotydyl transferase mediated dutp nick-end labeling (tunel) staining and mrnas were analyzed by real time qrt-pcr. |
2015-06-22 |
2023-08-13 |
human |
J Long, Y X Su, H C Den. Lipoapoptosis pathways in pancreatic β-cells and the anti-apoptosis mechanisms of adiponectin. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 46. issue 10. 2015-06-16. PMID:25028793. |
when adiponectin was used, min 6 cultures were pretreated in the absence or presence of fad (5 μg/ml) for 2 h and then subjected to palmitate for 24 h. apoptosis was evaluated using annexin v-cy3 kit. |
2015-06-16 |
2023-08-13 |
Not clear |
Ji-Xiang Zhang, Zi-Rong Yang, Dan-Dan Wu, Jia Song, Xu-Feng Guo, Jing Wang, Wei-Guo Don. Suppressive effect of sinomenine combined with 5-fluorouracil on colon carcinoma cell growth. Asian Pacific journal of cancer prevention : APJCP. vol 15. issue 16. 2015-06-08. PMID:25169518. |
cck-8, hoechst 33258 staining and an annexin v-fitc/pi apoptosis kit were used to detect suppressive effects. |
2015-06-08 |
2023-08-13 |
mouse |
Jiaoyang Luo, Yichen Hu, Weijun Kong, Meihua Yan. Evaluation and structure-activity relationship analysis of a new series of arylnaphthalene lignans as potential anti-tumor agents. PloS one. vol 9. issue 3. 2015-05-28. PMID:24675875. |
apoptosis was measured by both the using a cycle test plus dna reagent kit as well as the fitc annexin v apoptosis detection kit in combination with flow cytometry. |
2015-05-28 |
2023-08-12 |
human |
Jiaoyang Luo, Yichen Hu, Weijun Kong, Meihua Yan. Evaluation and structure-activity relationship analysis of a new series of arylnaphthalene lignans as potential anti-tumor agents. PloS one. vol 9. issue 3. 2015-05-28. PMID:24675875. |
activation of caspase-mediated apoptosis was evaluated using a fitc active caspase-3 apoptosis kit and flow cytometry. |
2015-05-28 |
2023-08-12 |
human |
Zhengjun Peng, Lu Liu, Xi Wei, Junqi Lin. Expression of Oct-4, SOX-2, and MYC in dental papilla cells and dental follicle cells during in-vivo tooth development and in-vitro co-culture. European journal of oral sciences. vol 122. issue 4. 2015-05-28. PMID:25039286. |
cell proliferation, cell apoptosis, cell cycle stages, and expression of osm were investigated by cell counting kit 8 (cck8) analysis, flow cytometry, real-time pcr, and immunohistochemical staining. |
2015-05-28 |
2023-08-13 |
rat |
Jiao Liu, Ying Liang, Ting Liu, Dengke Li, Xingsheng Yan. Anti-EGFR-Conjugated Hollow Gold Nanospheres Enhance Radiocytotoxic Targeting of Cervical Cancer at Megavoltage Radiation Energies. Nanoscale research letters. vol 10. 2015-05-21. PMID:25995714. |
cell cycle and apoptosis were examined by an annexin v-fitc/propidium iodide (pi) kit with flow cytometry (fcm). |
2015-05-21 |
2023-08-13 |
Not clear |
Shu-Tong Yao, Cheng Miao, Qing-Hua Liu, Yan-Yan Li, Hua Tian, Yun-Yun Wang, Bian-Ying Ma, Yong-Qi Fang, Shu-Cun Qi. [Inhibitory effect of quercetin preconditioning on tunicamycin-induced apoptosis in macrophages and its mechanism]. Sheng li xue bao : [Acta physiologica Sinica]. vol 65. issue 1. 2015-05-16. PMID:23426513. |
raw264.7 cells were pretreated with different concentrations (20, 40, and 80 μmol/l) of que for 30 min and then treated with tm (5 mg/l) for 12 h. cell viability and apoptosis were determined using mtt assay and annexin v-fitc apoptosis detection kit, respectively. |
2015-05-16 |
2023-08-12 |
Not clear |
Jun Lu, Hui-Yue Dong, Ling-Jing Lin, Qing-Hua Wang, Liang-Hu Huang, Jian-Ming Ta. [Palmitate induces apoptosis and endoplasmic reticulum stress in human umbilical cord-derived mesenchymal stem cells]. Sheng li xue bao : [Acta physiologica Sinica]. vol 65. issue 6. 2015-05-16. PMID:24343717. |
after administration with palmitate, apoptotic cell was assessed by flow cytometry using the annexin v-fitc/7-aad apoptosis detection kit. |
2015-05-16 |
2023-08-12 |
human |
Joshua Runtuwene, Haruka Amitani, Marie Amitani, Akihiro Asakawa, Kai-Chun Cheng, Akio Inu. Hydrogen-water enhances 5-fluorouracil-induced inhibition of colon cancer. PeerJ. vol 3. 2015-04-14. PMID:25870767. |
the survival rate was determined using the kaplan-meier survival test, and cell viability was assessed using cell viability imaging kit and the mtt assay, and activation of the cell apoptosis pathway (phosphorylated adenosine monophosphate activated protein kinase (p-ampk), apoptosis-inducing factor (aif) and caspase 3) were characterized by western blots. |
2015-04-14 |
2023-08-13 |
mouse |
Lesley A Mathews, Jonathan M Keller, Crystal McKnight, Sam Michael, Paul Shinn, Dongbo Liu, Louis M Staudt, Craig J Thomas, Marc Ferre. Multiplexing high-content flow (HCF) and quantitative high-throughput screening (qHTS) to identify compounds capable of decreasing cell viability, activating caspase 3/7, expressing annexin V, and changing mitochondrial membrane integrity. Current protocols in chemical biology. vol 5. issue 3. 2015-03-30. PMID:24391083. |
this article describes how qhts at the new national center for advancing translational science (ncats) has been systematically coupled with the htfc screening system and multimetric apoptosis screening kit from intellicyt to biologically validate active compounds from primary cell proliferation screens using a model of diffuse large b cell lymphoma (dlbcl). |
2015-03-30 |
2023-08-12 |
Not clear |
Xiao-Li Yang, Cheng-Dong Zhang, Hua-Yu Wu, Yong-Hu Wu, Yue-Ning Zhang, Meng-Bin Qin, Hua Wu, Xiao-Chun Liu, Xing Lina, Shao-Ming L. Effect of trichostatin A on CNE2 nasopharyngeal carcinoma cells--genome-wide DNA methylation alteration. Asian Pacific journal of cancer prevention : APJCP. vol 15. issue 11. 2015-03-30. PMID:24969901. |
after cells were treated by tsa, the inhibitory rate of cell proliferation was examined with a cck8 kit, and cell apoptosis was determined by flow cytometry. |
2015-03-30 |
2023-08-13 |
Not clear |
Jichun Han, Dong Wang, Bacui Yu, Yanming Wang, Huanhuan Ren, Bo Zhang, Yonghua Wang, Qiusheng Zhen. Cardioprotection against ischemia/reperfusion by licochalcone B in isolated rat hearts. Oxidative medicine and cellular longevity. vol 2014. 2015-03-30. PMID:25215172. |
cardiomyocyte apoptosis analysis was performed using the in situ cell death detection kit, pod. |
2015-03-30 |
2023-08-13 |
rat |
Shuang Yu, Chuanfang Liu, Lanhua Li, Tian Tian, Min Wang, Yu Hu, Cunzhong Yuan, Lei Zhang, Chunyan Ji, Daoxin M. Inactivation of Notch signaling reverses the Th17/Treg imbalance in cells from patients with immune thrombocytopenia. Laboratory investigation; a journal of technical methods and pathology. vol 95. issue 2. 2015-03-29. PMID:25485537. |
cell proliferation and apoptosis were determined by the cell counting kit-8 and apoptosis detection kit. |
2015-03-29 |
2023-08-13 |
human |
Miroslav Barancik, Viera Bohacova, Lenka Gibalova, Jan Sedlak, Zdena Sulova, Albert Breie. Potentiation of anticancer drugs: effects of pentoxifylline on neoplastic cells. International journal of molecular sciences. vol 13. issue 1. 2015-02-26. PMID:22312258. |
the effects of ptx on the sensitization of l1210/vcr cells to vcr correlate with the stimulation of apoptosis detected by annexin v/propidium iodide apoptosis necrosis kit and proteolytic activation of both caspase-3 and caspase-9 monitored by western blot analysis. |
2015-02-26 |
2023-08-12 |
mouse |
Xing-Long Liu, Yu-Han Meng, Jian-Li Wang, Biao-Bing Yang, Fan Zhang, Sheng-Jian Tan. FOXL2 suppresses proliferation, invasion and promotes apoptosis of cervical cancer cells. International journal of clinical and experimental pathology. vol 7. issue 4. 2015-02-23. PMID:24817949. |
when foxl2 was overexpressed or silenced, cells proliferation and apoptosis were determined by brdu assay and annexin v/pi detection kit, respectively. |
2015-02-23 |
2023-08-13 |
Not clear |
Chang-Feng Li, Li-Bo Chen, Dan-Dan Li, Lei Yang, Bao-Gang Zhang, Jing-Peng Jin, Ying Zhang, Bin Zhan. Dual‑sensitive HRE/Egr1 promoter regulates Smac overexpression and enhances radiation‑induced A549 human lung adenocarcinoma cell death under hypoxia. Molecular medicine reports. vol 10. issue 2. 2015-02-12. PMID:24842518. |
an mtt assay was performed to detect cell proliferation and an annexin v‑fluorescein isothiocyanate apoptosis detection kit was used to detect apoptosis. |
2015-02-12 |
2023-08-13 |
human |