| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Huiyan Hu, Yanfang Fu, Bo Zhou, Zhiqiang Li, Zhongwu Liu, Qing Ji. Long non-coding RNA TCONS_00814106 regulates porcine granulosa cell proliferation and apoptosis by sponging miR-1343. Molecular and cellular endocrinology. vol 520. 2021-08-12. PMID:33091558. |
cell counting kit (cck)-8 and apoptosis assays showed that tcons_00814106 promotes proliferation and inhibits apoptosis in porcine granulosa cells (gcs), and that this could be reversed by mir-1343. |
2021-08-12 |
2023-08-13 |
Not clear |
| Lai Chen, Shaohui Zhang, Xiaoying Liu, Jiong Dai, Zhenguo Yan, Chunlan W. Effects of dendrobium polysaccharides on human brain microvascular endothelial cell injury induced by ox-LDL via regulating the miR-378 expression. Cellular and molecular biology (Noisy-le-Grand, France). vol 66. issue 7. 2021-08-06. PMID:33287924. |
the kit was used to detect the levels of malondialdehyde (mda) and the activities of superoxide dismutase (sod) and catalase (cat); flow cytometry to detect apoptosis; and western blot to detect b-cell lymph tumor/leukemia-2 (bcl-2) and bcl-2 related x (bax) protein expression; real-time fluorescence quantitative pcr (rt-qpcr) was used to detect the expression of mir-378. |
2021-08-06 |
2023-08-13 |
human |
| Kuo Wang, Nan Zhang, Zhanbiao Yu, Ning L. Galactose protects pancreatic acinar cells from cerulein induced damage by regulating FGF21 and Klotho. Pakistan journal of pharmaceutical sciences. vol 33. issue 3(Special). 2021-08-06. PMID:33361031. |
acute pancreatitis cell injury model was established by arbusin-induced pancreatic acinar cell ar42j injury; galactose (25, 50, 100 mmol / l) was used to treat the injured cells, and the optimal concentration was 50 mmol / l; cell counting kit (cck-8), enzyme linked immunosorbent assay (elisa) to detect cell survival rate and necrosis rate; flow cytometry and western blotting (western blot) to detect cell apoptosis and autologous phage-related gene (beclin1) and microtubule-associated protein 1 light chain 3 (lc3), apoptosis-related protein b-cell lymphoma / leukemia-2 (bcl-2), bcl-2-related x gene (bax), and fibroblasts expression of growth factor 21 antibody (fgf21) and anti-aging gene klotho. |
2021-08-06 |
2023-08-13 |
Not clear |
| Yuan Cai, Qing Du, Tian-Hao Deng, Bing-Bing Shen, Yan-Mei Peng, Pu-Hua Zeng, Song-Ren Y. Huxie Huaji Ointment Induced Apoptosis of Liver Cancer Cells In Vivo and In Vitro by Activating the Mitochondrial Pathway. Evidence-based complementary and alternative medicine : eCAM. vol 2021. 2021-08-03. PMID:34335843. |
second, in vitro, cell counting kit (cck8) cell viability assay and hoechst 33342 staining assay were performed to explain the cell apoptosis. |
2021-08-03 |
2023-08-13 |
Not clear |
| Qifeng Yu, Wei Zhang, Xin Zhou, Wenqi Shen, Chungen Xing, Xiaodong Yan. Regulation of lnc-TLCD2-1 on Radiation Sensitivity of Colorectal Cancer and Comprehensive Analysis of Its Mechanism. Frontiers in oncology. vol 11. 2021-08-03. PMID:34336703. |
cell clone formation assay, flow cytometry, and cell counting kit 8 (cck8) were used to detect radiation sensitivity, apoptosis, and proliferation of colorectal cancer cells, respectively; quantitative real-time pcr and western blot were used to detect the expression of genes; the direct interaction between lnc-tlcd2-1 and hsa-mir-193a-5p was verified by dual luciferase reporter assays; gepia, starbase, timer and david were used to complete expression of lnc-tlcd2-1, mir-193a-5p,yy1 and nf-кb-p65 in colorectal cancer, correlation, immune cell infiltration, go and kegg enrichment analysis. |
2021-08-03 |
2023-08-13 |
Not clear |
| Jinxing Hu, Zeqi Zheng, Xuelian Li, Bingong Li, Xingjun Lai, Na Li, Shufang Le. Metformin Attenuates Hypoxia-induced Endothelial Cell Injury by Activating the AMP-Activated Protein Kinase Pathway. Journal of cardiovascular pharmacology. vol 77. issue 6. 2021-08-02. PMID:33929389. |
flow cytometry and cell counting kit 8 were used to monitor apoptosis and assess cell viability. |
2021-08-02 |
2023-08-13 |
human |
| Mingming Tan, Rongxin Be. Circ_0091702 serves as a sponge of miR-545-3p to attenuate sepsis-related acute kidney injury by upregulating THBS2. Journal of molecular histology. vol 52. issue 4. 2021-08-02. PMID:34101064. |
cell counting kit 8 assay and flow cytometry were used to assess cell viability and apoptosis. |
2021-08-02 |
2023-08-13 |
human |
| Li-Chuan Liang, Lin-Qing Liu, Liu Liu, Dong-Liang Liu, Yi-Ren He, Xiao Wan, Zhi-Qiang Zhu, Bao-Gui Zhang, Shao-Jun Liu, Huo Wu, Lei H. Long non-coding RNA BX357664 inhibits gastric cancer progression by sponging miR-183a-3p to regulate the PTEN expression and PI3K/AKT pathway. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 150. 2021-07-30. PMID:33607219. |
also, we used cell counting kit 8 (cck8), cell clone formation assay and transwell assay, which affirmed that up-regulation of bx357664 inhibited the proliferation, migration, and invasion of gc cells, but promoted apoptosis. |
2021-07-30 |
2023-08-13 |
Not clear |
| Lei Jiang, Luyao Zhang, Qian Chen, Shigang Qiao, Feng Zhou, Min Ha. LncRNA HEIH promotes cell proliferation, migration and invasion by suppressing miR-214-3p in gastric carcinoma. Journal of biochemistry. vol 169. issue 5. 2021-07-29. PMID:33226411. |
an annexin v-fluorescein-isothiocyanate (fitc)/propidium iodide (pi) apoptosis detection kit was used to evaluate the apoptosis ratio. |
2021-07-29 |
2023-08-13 |
Not clear |
| Min Wang, Hideki Hayashi, Ichiro Horinokita, Mayumi Asada, Yui Iwatani, Jian-Xun Liu, Norio Takag. Neuroprotective effects of Senkyunolide I against glutamate-induced cells death by attenuating JNK/caspase-3 activation and apoptosis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 140. 2021-07-29. PMID:34044281. |
cell viability was assessed by using wst-1 reagents, and apoptosis was evaluated using annexin v-fitc and a pi double staining kit. |
2021-07-29 |
2023-08-13 |
mouse |
| Katarzyna Gębczak, Benita Wiatrak, Wojciech Fortun. Evaluation of PC12 Cells' Proliferation, Adhesion and Migration with the Use of an Extracellular Matrix (CorMatrix) for Application in Neural Tissue Engineering. Materials (Basel, Switzerland). vol 14. issue 14. 2021-07-29. PMID:34300779. |
the number of pc12 cells was counted at four time points and then analysed for apoptosis using a staining kit containing annexin v conjugate with fluorescein and propidium iodide (pi). |
2021-07-29 |
2023-08-13 |
rat |
| Bai-Ling Sun, En-Bo Cai, Yan Zhao, Yu Wang, Li-Min Yang, Jing-Yao Wan. Arctigenin Triggers Apoptosis and Autophagy via PI3K/Akt/mTOR Inhibition in PC-3M Cells. Chemical & pharmaceutical bulletin. vol 69. issue 5. 2021-07-27. PMID:33627540. |
annexin v-fluoresceine isothiocyanate/propidium iodide (fitc/pi) kit and 4',6-diamidino-2-phenylindole (dapi) staining were used to detect the apoptosis level, and cell cycle changes were analyzed by flow cytometry. |
2021-07-27 |
2023-08-13 |
Not clear |
| Ying Zhang, Qihong Zhao, Xiaohong Li, Fuhai J. Dexmedetomidine reversed hypoxia/reoxygenation injury-induced oxidative stress and endoplasmic reticulum stress-dependent apoptosis of cardiomyocytes via SIRT1/CHOP signaling pathway. Molecular and cellular biochemistry. vol 476. issue 7. 2021-07-27. PMID:33725228. |
cell counting kit (cck)-8 assay was used to detect cell survival rate while flow cytometry and caspase 3/7 activity were used to determine cell apoptosis, respectively. |
2021-07-27 |
2023-08-13 |
cat |
| Vida Celeste Rosas-González, Martha Cecilia Téllez-Bañuelos, Georgina Hernández-Flores, Alejandro Bravo-Cuellar, Adriana Aguilar-Lemarroy, Luis Felipe Jave-Suárez, Jesse Haramati, Fabiola Solorzano-Ibarra, Pablo Cesar Ortiz-Lazaren. Differential effects of alliin and allicin on apoptosis and senescence in luminal A and triple-negative breast cancer: Caspase, ΔΨm, and pro-apoptotic gene involvement. Fundamental & clinical pharmacology. vol 34. issue 6. 2021-07-26. PMID:32286702. |
apoptosis and caspase activity were evaluated by flow cytometry; ΔΨm was assessed using a jc-10 fluorometric assay kit. |
2021-07-26 |
2023-08-13 |
Not clear |
| Xue-Wu Xing, Hong-Yu Shi, Shen Liu, Shu-Xin Feng, Shi-Qing Feng, Bao-Qi Gon. miR-496/MMP10 Is Involved in the Proliferation of IL-1β-Induced Fibroblast-Like Synoviocytes Via Mediating the NF-κB Signaling Pathway. Inflammation. vol 44. issue 4. 2021-07-19. PMID:33548006. |
cell counting kit 8 (cck-8) and flow cytometry experiments were implemented to investigate the cell viability and apoptosis rate of mh7a cells. |
2021-07-19 |
2023-08-13 |
Not clear |
| Wenwen Du, Li Wang, Zhen Liao, Juan Wan. Circ_0085289 Alleviates the Progression of Periodontitis by Regulating let-7f-5p/SOCS6 Pathway. Inflammation. vol 44. issue 4. 2021-07-19. PMID:33710445. |
cell viability and apoptosis were determined using cell counting kit-8, flow cytometry, caspase-3 assay kit, and western blot assays. |
2021-07-19 |
2023-08-13 |
Not clear |
| Tao Zhang, Chun-Feng Liu, Tie-Ning Zhang, Ri Wen, Wen-Liang Son. Overexpression of Peroxisome Proliferator-Activated Receptor γ Coactivator 1-α Protects Cardiomyocytes from Lipopolysaccharide-Induced Mitochondrial Damage and Apoptosis. Inflammation. vol 43. issue 5. 2021-07-15. PMID:32529514. |
an apoptosis analysis kit was used to measure cellular apoptosis. |
2021-07-15 |
2023-08-13 |
rat |
| Fang Liu, Yan-Li Wang, Jie-Mei Wei, Zhao-Dong Huan. Upregulation of circ_0000142 promotes multiple myeloma progression by adsorbing miR-610 and upregulating AKT3 expression. Journal of biochemistry. vol 169. issue 3. 2021-07-15. PMID:32970816. |
cell proliferation, apoptosis, migration and invasion were monitored by cell counting kit 8 assay, flow cytometry analysis and transwell assay, respectively. |
2021-07-15 |
2023-08-13 |
Not clear |
| Haoren Qin, Heng Zhang, Xipeng Zhang, Shiwu Zhang, Siwei Zhu, Hui Wan. Resveratrol protects intestinal epithelial cells against radiation-induced damage by promoting autophagy and inhibiting apoptosis through SIRT1 activation. Journal of radiation research. vol 62. issue 4. 2021-07-14. PMID:33912959. |
cell viability was investigated using cell counting kit 8 (cck8), apoptosis was observed by annexin v-fluorescein isothiocyanate/propidium iodide (pi) staining and flow cytometry, and the expression of apoptotic and autophagic proteins was determined by western blotting. |
2021-07-14 |
2023-08-13 |
Not clear |
| Juan Tan, Weinan Pan, Huilin Chen, Yafang Du, Peiyong Jiang, Dianmei Zeng, Jie Wu, Kuang Pen. Circ_0124644 Serves as a ceRNA for miR-590-3p to Promote Hypoxia-Induced Cardiomyocytes Injury via Regulating SOX4. Frontiers in genetics. vol 12. 2021-07-13. PMID:34249089. |
cell counting kit 8 (cck8) assay and flow cytometry were utilized to detect cell viability, cell cycle progression, and apoptosis. |
2021-07-13 |
2023-08-13 |
Not clear |