| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jia Liu, Chaoyan Ou, Xiaonian Zhu, Chao Tan, Xuebao Xiang, Yonghua H. Potential role of CFTR in bisphenol A-induced malignant transformation of prostate cells via mitochondrial apoptosis. Toxicology and industrial health. vol 36. issue 8. 2021-09-06. PMID:32729384. |
cell apoptosis was analyzed with annexin v-fitc detection kit by flow cytometry. |
2021-09-06 |
2023-08-13 |
human |
| A Komsky-Elbaz, D Kalo, Z Rot. Carryover effect of atrazine and its metabolite-from treated bovine spermatozoa to the embryo's transcriptome†. Biology of reproduction. vol 104. issue 5. 2021-09-06. PMID:33624745. |
the association between dna fragmentation and apoptosis (annexin v kit) was determined. |
2021-09-06 |
2023-08-13 |
cattle |
| Yanlin Yang, Haixia Shan. Silencing lncRNA-DGCR5 increased trophoblast cell migration, invasion and tube formation, and inhibited cell apoptosis via targeting miR-454-3p/GADD45A axis. Molecular and cellular biochemistry. vol 476. issue 9. 2021-09-06. PMID:33973132. |
the viability, apoptosis, migration, invasiveness and tube formation of htr-8/svneo cell were evaluated using cell counting kit (cck)-8, annexin-v/propidium iodide staining, wound healing, transwell and tube formation assays, respectively. |
2021-09-06 |
2023-08-13 |
Not clear |
| Hui Li, Wen Cao, Xun-Bin Zhang, Xi-Xia Zhang, Chao Gu, Li-Mei Gu, Cheng-Yu Pan, Yao-Zhou Tian, Min L. Atractylenolide‑1 alleviates gastroparesis in diabetic rats by activating the stem cell factor/c‑kit signaling pathway. Molecular medicine reports. vol 24. issue 4. 2021-09-02. PMID:34368880. |
moreover, the stz‑induced group displayed downregulated expression levels of the dgp indicator kit proto‑oncogene, receptor tyrosine kinase (c‑kit), as investigated by immunohistochemistry, and stem cell factor (scf) protein, as assessed using elisa, significantly enhanced rat interstitial cells of cajal (icc) apoptosis, and significantly altered levels of oxidative stress‑related markers (malondialdehyde and superoxide dismutase) in the serum and gastric tissues compared with the vehicle control group. |
2021-09-02 |
2023-08-13 |
rat |
| Lian Zeng, Fuyu Zhang, Zhen Zhang, Min Xu, Yang Xu, Ying Liu, Hongxia Xu, Xiaodong Sun, Ming Sang, Huiyu Lu. P53 inhibitor pifithrin-α inhibits ropivacaine-induced neuronal apoptosis via the mitochondrial apoptosis pathway. Journal of biochemical and molecular toxicology. vol 35. issue 8. 2021-09-01. PMID:34091999. |
cell viability and apoptosis detected by cck-8 and a jc-1 apoptosis detection kit, the changes of spinal cord structure observed after hematoxylin and eosin staining, apoptosis of the spinal cord measured by terminal deoxynucleotidyl transferase dutp nick end labeling staining, behavioral assessment of the nerve injury evaluated by the detection of sciatic nerve conduction velocity (sncv) andmechanical withdrawal threshold (mwt), the expression of p53 and many apoptosis-related genes included bax, bcl-2, and caspase-3 detected by quantitative real-time polymerase chain reaction, western blot analysis, immunofluorescence, and immunohistochemistry. |
2021-09-01 |
2023-08-13 |
Not clear |
| Adam Wawrzynkiewicz, Wioletta Rozpedek-Kaminska, Grzegorz Galita, Monika Lukomska-Szymanska, Barbara Lapinska, Jerzy Sokolowski, Ireneusz Majstere. The Toxicity of Universal Dental Adhesives: An In Vitro Study. Polymers. vol 13. issue 16. 2021-08-31. PMID:34451192. |
furthermore, flow cytometry (fc) apoptosis detection was performed using the fitc annexin v apoptosis detection kit i. fc cell-cycle arrest assessment was performed using propidium iodide staining. |
2021-08-31 |
2023-08-13 |
Not clear |
| Yujie Su, Guoqing Chen, Faqiang Zhang, Long Wang, Zeguo Feng, Xiangmei Ga. Isoflurane Alleviates Myocardial Injury Induced by Hypoxia/Reoxygenation by Regulating miR-18a-5p. Cardiovascular toxicology. vol 21. issue 10. 2021-08-30. PMID:34181233. |
cck-8 kit and flow cytometry were performed to evaluate cell proliferation and apoptosis. |
2021-08-30 |
2023-08-13 |
Not clear |
| Bin Shen, Lan Wang, Yuejun Xu, Hongwei Wang, Shiyi H. Knockdown of lncRNA SNHG15 Ameliorates Oxygen and Glucose Deprivation (OGD)-Induced Neuronal Injury via Regulating the miR-9-5p/TIPARP Axis. Biochemical genetics. 2021-08-28. PMID:34453220. |
cell-counting kit 8 assay and flow cytometry were used to detect cell viability and apoptosis, respectively. |
2021-08-28 |
2023-08-13 |
mouse |
| Monika E Grabowska, Bryan Chun, Raquel Moya, Jeffrey J Saucerma. Computational model of cardiomyocyte apoptosis identifies mechanisms of tyrosine kinase inhibitor-induced cardiotoxicity. Journal of molecular and cellular cardiology. vol 155. 2021-08-25. PMID:33667419. |
a combinatorial screen of the positive and negative regulators of sorafenib-induced apoptosis revealed ros knockdown coupled with overexpression of flt3, fgfr, pdgfr, vegfr, or kit as a particularly potent combination in reducing sorafenib-induced apoptosis. |
2021-08-25 |
2023-08-13 |
Not clear |
| Donglin Zheng, Mengmeng Li, Guofei Li, Jing Hu, Xin Jiang, Yabo Wang, Yuhua Su. Circular RNA circ_DROSHA alleviates the neural damage in a cell model of temporal lobe epilepsy through regulating miR-106b-5p/MEF2C axis. Cellular signalling. vol 80. 2021-08-23. PMID:33370579. |
cell proliferation was detected by the cell counting-8 kit (cck-8) assay, and cell apoptosis was measured by flow cytometry. |
2021-08-23 |
2023-08-13 |
Not clear |
| Lin Jiang, Jiangwei Shen, Ning Zhang, Yongchao He, Zhenghua Wa. Association of RGS20 expression with the progression and prognosis of renal cell carcinoma. Oncology letters. vol 22. issue 3. 2021-08-14. PMID:34386065. |
after rgs20 inhibition, the proliferation, apoptosis, migration and invasiveness of a-498 cells were tested using mtt assay, edu assay, propidium iodide staining, annexin v-fitc/pi kit, wound healing assay and transwell assay. |
2021-08-14 |
2023-08-13 |
Not clear |
| Qiuwang Zhang, Chenxi Wang, Anthony Cannavicci, Marie E Faughnan, Michael J B Kutry. Endoglin deficiency impairs VEGFR2 but not FGFR1 or TIE2 activation and alters VEGF-mediated cellular responses in human primary endothelial cells. Translational research : the journal of laboratory and clinical medicine. vol 235. 2021-08-13. PMID:33894400. |
cell migration and apoptosis were assessed using the boyden chamber assay and the cck-8 kit, respectively. |
2021-08-13 |
2023-08-13 |
human |
| Huiyan Hu, Yanfang Fu, Bo Zhou, Zhiqiang Li, Zhongwu Liu, Qing Ji. Long non-coding RNA TCONS_00814106 regulates porcine granulosa cell proliferation and apoptosis by sponging miR-1343. Molecular and cellular endocrinology. vol 520. 2021-08-12. PMID:33091558. |
cell counting kit (cck)-8 and apoptosis assays showed that tcons_00814106 promotes proliferation and inhibits apoptosis in porcine granulosa cells (gcs), and that this could be reversed by mir-1343. |
2021-08-12 |
2023-08-13 |
Not clear |
| Lai Chen, Shaohui Zhang, Xiaoying Liu, Jiong Dai, Zhenguo Yan, Chunlan W. Effects of dendrobium polysaccharides on human brain microvascular endothelial cell injury induced by ox-LDL via regulating the miR-378 expression. Cellular and molecular biology (Noisy-le-Grand, France). vol 66. issue 7. 2021-08-06. PMID:33287924. |
the kit was used to detect the levels of malondialdehyde (mda) and the activities of superoxide dismutase (sod) and catalase (cat); flow cytometry to detect apoptosis; and western blot to detect b-cell lymph tumor/leukemia-2 (bcl-2) and bcl-2 related x (bax) protein expression; real-time fluorescence quantitative pcr (rt-qpcr) was used to detect the expression of mir-378. |
2021-08-06 |
2023-08-13 |
human |
| Kuo Wang, Nan Zhang, Zhanbiao Yu, Ning L. Galactose protects pancreatic acinar cells from cerulein induced damage by regulating FGF21 and Klotho. Pakistan journal of pharmaceutical sciences. vol 33. issue 3(Special). 2021-08-06. PMID:33361031. |
acute pancreatitis cell injury model was established by arbusin-induced pancreatic acinar cell ar42j injury; galactose (25, 50, 100 mmol / l) was used to treat the injured cells, and the optimal concentration was 50 mmol / l; cell counting kit (cck-8), enzyme linked immunosorbent assay (elisa) to detect cell survival rate and necrosis rate; flow cytometry and western blotting (western blot) to detect cell apoptosis and autologous phage-related gene (beclin1) and microtubule-associated protein 1 light chain 3 (lc3), apoptosis-related protein b-cell lymphoma / leukemia-2 (bcl-2), bcl-2-related x gene (bax), and fibroblasts expression of growth factor 21 antibody (fgf21) and anti-aging gene klotho. |
2021-08-06 |
2023-08-13 |
Not clear |
| Yuan Cai, Qing Du, Tian-Hao Deng, Bing-Bing Shen, Yan-Mei Peng, Pu-Hua Zeng, Song-Ren Y. Huxie Huaji Ointment Induced Apoptosis of Liver Cancer Cells In Vivo and In Vitro by Activating the Mitochondrial Pathway. Evidence-based complementary and alternative medicine : eCAM. vol 2021. 2021-08-03. PMID:34335843. |
second, in vitro, cell counting kit (cck8) cell viability assay and hoechst 33342 staining assay were performed to explain the cell apoptosis. |
2021-08-03 |
2023-08-13 |
Not clear |
| Qifeng Yu, Wei Zhang, Xin Zhou, Wenqi Shen, Chungen Xing, Xiaodong Yan. Regulation of lnc-TLCD2-1 on Radiation Sensitivity of Colorectal Cancer and Comprehensive Analysis of Its Mechanism. Frontiers in oncology. vol 11. 2021-08-03. PMID:34336703. |
cell clone formation assay, flow cytometry, and cell counting kit 8 (cck8) were used to detect radiation sensitivity, apoptosis, and proliferation of colorectal cancer cells, respectively; quantitative real-time pcr and western blot were used to detect the expression of genes; the direct interaction between lnc-tlcd2-1 and hsa-mir-193a-5p was verified by dual luciferase reporter assays; gepia, starbase, timer and david were used to complete expression of lnc-tlcd2-1, mir-193a-5p,yy1 and nf-кb-p65 in colorectal cancer, correlation, immune cell infiltration, go and kegg enrichment analysis. |
2021-08-03 |
2023-08-13 |
Not clear |
| Jinxing Hu, Zeqi Zheng, Xuelian Li, Bingong Li, Xingjun Lai, Na Li, Shufang Le. Metformin Attenuates Hypoxia-induced Endothelial Cell Injury by Activating the AMP-Activated Protein Kinase Pathway. Journal of cardiovascular pharmacology. vol 77. issue 6. 2021-08-02. PMID:33929389. |
flow cytometry and cell counting kit 8 were used to monitor apoptosis and assess cell viability. |
2021-08-02 |
2023-08-13 |
human |
| Mingming Tan, Rongxin Be. Circ_0091702 serves as a sponge of miR-545-3p to attenuate sepsis-related acute kidney injury by upregulating THBS2. Journal of molecular histology. vol 52. issue 4. 2021-08-02. PMID:34101064. |
cell counting kit 8 assay and flow cytometry were used to assess cell viability and apoptosis. |
2021-08-02 |
2023-08-13 |
human |
| Li-Chuan Liang, Lin-Qing Liu, Liu Liu, Dong-Liang Liu, Yi-Ren He, Xiao Wan, Zhi-Qiang Zhu, Bao-Gui Zhang, Shao-Jun Liu, Huo Wu, Lei H. Long non-coding RNA BX357664 inhibits gastric cancer progression by sponging miR-183a-3p to regulate the PTEN expression and PI3K/AKT pathway. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 150. 2021-07-30. PMID:33607219. |
also, we used cell counting kit 8 (cck8), cell clone formation assay and transwell assay, which affirmed that up-regulation of bx357664 inhibited the proliferation, migration, and invasion of gc cells, but promoted apoptosis. |
2021-07-30 |
2023-08-13 |
Not clear |