| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shuqi Meng, Xiaotong Sun, Zhaodong Juan, Mingling Wang, Ruoguo Wang, Lina Sun, Yaozu Li, Anran Xin, Shuping Li, Yao L. Clemastine Fumarate Attenuates Myocardial Ischemia Reperfusion Injury Through Inhibition of Mast Cell Degranulation. Frontiers in pharmacology. vol 12. 2021-09-14. PMID:34512339. |
apoptosis of h9c2 cells was detected by cck-8, the ldh cytotoxicity assay kit (ldh), tunel staining, and protein expression of bax and bcl-2. |
2021-09-14 |
2023-08-13 |
rat |
| Niloufar Targhazeh, Bahman Yousefi, Samira Asghari, Reza Mohammadnejhad, Parinaz Mansouri, Amir Valizade. MiR-622 acts as a tumor suppressor to induce cell apoptosis and inhibit metastasis in human prostate cancer. Andrologia. vol 53. issue 9. 2021-09-13. PMID:34231241. |
apoptosis was detected using an elisa cell death assay kit. |
2021-09-13 |
2023-08-13 |
human |
| Douglas B Snider, Greer K Arthur, Guido H Falduto, Ana Olivera, Lauren C Ehrhardt-Humbert, Emmaline Smith, Cierra Smith, Dean D Metcalfe, Glenn Crus. Targeting KIT by frameshifting mRNA transcripts as a therapeutic strategy for aggressive mast cell neoplasms. Molecular therapy : the journal of the American Society of Gene Therapy. 2021-09-11. PMID:34371183. |
the result of this alternate approach results in marked downregulation of kit expression, diminished kit signaling, inhibition of mc proliferation, and rapid induction of apoptosis in neoplastic hmc-1.2 mcs. |
2021-09-11 |
2023-08-13 |
Not clear |
| Chunlai Shi, Xuan Li, Fei Hong, Xueyan Wang, Tingting Jiang, Bingbing Sun, Shuang L. Latent-transforming growth factor β-binding protein 2 accelerates cardiac fibroblast apoptosis by regulating the expression and activity of caspase-3. Experimental and therapeutic medicine. vol 22. issue 4. 2021-09-11. PMID:34504591. |
caspase-3 activity was therefore determined using a caspase-3 assay kit, cck8 was used to determine the rate of cell proliferation and apoptosis rates were quantified using a cell death detection elisa kit. |
2021-09-11 |
2023-08-13 |
mouse |
| Bum Jun Kim, Yoo Jin Kim, Sung-Hwa Sohn, Bohyun Kim, Hee Jung Sul, Hyeong Su Kim, Dae Young Zan. Tivantinib inhibits the VEGF signaling pathway and induces apoptosis in gastric cancer cells with c-MET or VEGFA amplification. Investigational new drugs. vol 38. issue 6. 2021-09-10. PMID:32361789. |
to examine the inhibitory effect of tivantinib on gc cells, we conducted apoptosis analysis using an annexin v-apc/pi apoptosis detection kit and trans-well migration assay with human gc cell lines. |
2021-09-10 |
2023-08-13 |
human |
| Yanhui Zhu, Chengwei Zou, Yanting Jia, Haizhou Zhang, Xiaochun Ma, Jun Zhan. Knockdown of circular RNA circMAT2B reduces oxygen-glucose deprivation-induced inflammatory injury in H9c2 cells through up-regulating miR-133. Cell cycle (Georgetown, Tex.). vol 19. issue 20. 2021-09-09. PMID:32897801. |
cell activity, apoptosis, ros generation and release of inflammatory factors were assessed by cck-8, flow cytometry, ros species assay kit and elisa, respectively. |
2021-09-09 |
2023-08-13 |
Not clear |
| David C Plachetzki, M Sabrina Pankey, Matthew D MacManes, Michael P Lesser, Charles W Walke. The Genome of the Softshell Clam Mya arenaria and the Evolution of Apoptosis. Genome biology and evolution. vol 12. issue 10. 2021-09-08. PMID:32653903. |
our results challenge the current understanding of the evolution of apoptosis and highlight the ancestral complexity of the bilaterian apoptotic tool kit and its subsequent dismantlement during the ecdysozoan radiation. |
2021-09-08 |
2023-08-13 |
Not clear |
| Shican Zhou, Hang Wu, Wenjuan Ning, Xiao Wu, Xiaoxiao Xu, Yuanqiao Ma, Xingwang Li, Junhong Hu, Chenyu Wang, Junpeng Wan. Ivermectin has New Application in Inhibiting Colorectal Cancer Cell Growth. Frontiers in pharmacology. vol 12. 2021-09-07. PMID:34483925. |
we used cck-8 assay to determine the cell viability, used an optical microscope to measure cell morphology, used annexin v-fitc/7-aad kit to determine cell apoptosis, used caspase 3/7 activity apoptosis assay kit to evaluate caspase 3/7 activity, used western blot to determine apoptosis-associated protein expression, and used flow cytometry and fluorescence microscope to determine the reactive oxygen species (ros) levels and cell cycle. |
2021-09-07 |
2023-08-13 |
human |
| Jia Liu, Chaoyan Ou, Xiaonian Zhu, Chao Tan, Xuebao Xiang, Yonghua H. Potential role of CFTR in bisphenol A-induced malignant transformation of prostate cells via mitochondrial apoptosis. Toxicology and industrial health. vol 36. issue 8. 2021-09-06. PMID:32729384. |
cell apoptosis was analyzed with annexin v-fitc detection kit by flow cytometry. |
2021-09-06 |
2023-08-13 |
human |
| A Komsky-Elbaz, D Kalo, Z Rot. Carryover effect of atrazine and its metabolite-from treated bovine spermatozoa to the embryo's transcriptome†. Biology of reproduction. vol 104. issue 5. 2021-09-06. PMID:33624745. |
the association between dna fragmentation and apoptosis (annexin v kit) was determined. |
2021-09-06 |
2023-08-13 |
cattle |
| Yanlin Yang, Haixia Shan. Silencing lncRNA-DGCR5 increased trophoblast cell migration, invasion and tube formation, and inhibited cell apoptosis via targeting miR-454-3p/GADD45A axis. Molecular and cellular biochemistry. vol 476. issue 9. 2021-09-06. PMID:33973132. |
the viability, apoptosis, migration, invasiveness and tube formation of htr-8/svneo cell were evaluated using cell counting kit (cck)-8, annexin-v/propidium iodide staining, wound healing, transwell and tube formation assays, respectively. |
2021-09-06 |
2023-08-13 |
Not clear |
| Hui Li, Wen Cao, Xun-Bin Zhang, Xi-Xia Zhang, Chao Gu, Li-Mei Gu, Cheng-Yu Pan, Yao-Zhou Tian, Min L. Atractylenolide‑1 alleviates gastroparesis in diabetic rats by activating the stem cell factor/c‑kit signaling pathway. Molecular medicine reports. vol 24. issue 4. 2021-09-02. PMID:34368880. |
moreover, the stz‑induced group displayed downregulated expression levels of the dgp indicator kit proto‑oncogene, receptor tyrosine kinase (c‑kit), as investigated by immunohistochemistry, and stem cell factor (scf) protein, as assessed using elisa, significantly enhanced rat interstitial cells of cajal (icc) apoptosis, and significantly altered levels of oxidative stress‑related markers (malondialdehyde and superoxide dismutase) in the serum and gastric tissues compared with the vehicle control group. |
2021-09-02 |
2023-08-13 |
rat |
| Lian Zeng, Fuyu Zhang, Zhen Zhang, Min Xu, Yang Xu, Ying Liu, Hongxia Xu, Xiaodong Sun, Ming Sang, Huiyu Lu. P53 inhibitor pifithrin-α inhibits ropivacaine-induced neuronal apoptosis via the mitochondrial apoptosis pathway. Journal of biochemical and molecular toxicology. vol 35. issue 8. 2021-09-01. PMID:34091999. |
cell viability and apoptosis detected by cck-8 and a jc-1 apoptosis detection kit, the changes of spinal cord structure observed after hematoxylin and eosin staining, apoptosis of the spinal cord measured by terminal deoxynucleotidyl transferase dutp nick end labeling staining, behavioral assessment of the nerve injury evaluated by the detection of sciatic nerve conduction velocity (sncv) andmechanical withdrawal threshold (mwt), the expression of p53 and many apoptosis-related genes included bax, bcl-2, and caspase-3 detected by quantitative real-time polymerase chain reaction, western blot analysis, immunofluorescence, and immunohistochemistry. |
2021-09-01 |
2023-08-13 |
Not clear |
| Adam Wawrzynkiewicz, Wioletta Rozpedek-Kaminska, Grzegorz Galita, Monika Lukomska-Szymanska, Barbara Lapinska, Jerzy Sokolowski, Ireneusz Majstere. The Toxicity of Universal Dental Adhesives: An In Vitro Study. Polymers. vol 13. issue 16. 2021-08-31. PMID:34451192. |
furthermore, flow cytometry (fc) apoptosis detection was performed using the fitc annexin v apoptosis detection kit i. fc cell-cycle arrest assessment was performed using propidium iodide staining. |
2021-08-31 |
2023-08-13 |
Not clear |
| Yujie Su, Guoqing Chen, Faqiang Zhang, Long Wang, Zeguo Feng, Xiangmei Ga. Isoflurane Alleviates Myocardial Injury Induced by Hypoxia/Reoxygenation by Regulating miR-18a-5p. Cardiovascular toxicology. vol 21. issue 10. 2021-08-30. PMID:34181233. |
cck-8 kit and flow cytometry were performed to evaluate cell proliferation and apoptosis. |
2021-08-30 |
2023-08-13 |
Not clear |
| Bin Shen, Lan Wang, Yuejun Xu, Hongwei Wang, Shiyi H. Knockdown of lncRNA SNHG15 Ameliorates Oxygen and Glucose Deprivation (OGD)-Induced Neuronal Injury via Regulating the miR-9-5p/TIPARP Axis. Biochemical genetics. 2021-08-28. PMID:34453220. |
cell-counting kit 8 assay and flow cytometry were used to detect cell viability and apoptosis, respectively. |
2021-08-28 |
2023-08-13 |
mouse |
| Monika E Grabowska, Bryan Chun, Raquel Moya, Jeffrey J Saucerma. Computational model of cardiomyocyte apoptosis identifies mechanisms of tyrosine kinase inhibitor-induced cardiotoxicity. Journal of molecular and cellular cardiology. vol 155. 2021-08-25. PMID:33667419. |
a combinatorial screen of the positive and negative regulators of sorafenib-induced apoptosis revealed ros knockdown coupled with overexpression of flt3, fgfr, pdgfr, vegfr, or kit as a particularly potent combination in reducing sorafenib-induced apoptosis. |
2021-08-25 |
2023-08-13 |
Not clear |
| Donglin Zheng, Mengmeng Li, Guofei Li, Jing Hu, Xin Jiang, Yabo Wang, Yuhua Su. Circular RNA circ_DROSHA alleviates the neural damage in a cell model of temporal lobe epilepsy through regulating miR-106b-5p/MEF2C axis. Cellular signalling. vol 80. 2021-08-23. PMID:33370579. |
cell proliferation was detected by the cell counting-8 kit (cck-8) assay, and cell apoptosis was measured by flow cytometry. |
2021-08-23 |
2023-08-13 |
Not clear |
| Lin Jiang, Jiangwei Shen, Ning Zhang, Yongchao He, Zhenghua Wa. Association of RGS20 expression with the progression and prognosis of renal cell carcinoma. Oncology letters. vol 22. issue 3. 2021-08-14. PMID:34386065. |
after rgs20 inhibition, the proliferation, apoptosis, migration and invasiveness of a-498 cells were tested using mtt assay, edu assay, propidium iodide staining, annexin v-fitc/pi kit, wound healing assay and transwell assay. |
2021-08-14 |
2023-08-13 |
Not clear |
| Qiuwang Zhang, Chenxi Wang, Anthony Cannavicci, Marie E Faughnan, Michael J B Kutry. Endoglin deficiency impairs VEGFR2 but not FGFR1 or TIE2 activation and alters VEGF-mediated cellular responses in human primary endothelial cells. Translational research : the journal of laboratory and clinical medicine. vol 235. 2021-08-13. PMID:33894400. |
cell migration and apoptosis were assessed using the boyden chamber assay and the cck-8 kit, respectively. |
2021-08-13 |
2023-08-13 |
human |