| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chang Li. Improvement effects of tanshinone on the impaired cognition and motor function in MCAO mice with ischemic penumbra. Pakistan journal of pharmaceutical sciences. vol 34. issue 3(Special). 2021-10-04. PMID:34602391. |
the tunel apoptosis detection kit was used to detect neuronal apoptosis. |
2021-10-04 |
2023-08-13 |
mouse |
| S Oka, X Li, F Zhang, C Taguchi, N Tewari, I-S Kim, L Zhong, K Arikawa, Y Liu, U K Bhawa. Oral toxicity to high level sodium fluoride causes impairment of autophagy. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 71. issue 5. 2021-10-01. PMID:33571967. |
human cementoblasts (hcem-2) in culture were exposed to 5 mm naf for 5 min, after which cell viability and cell apoptosis were assessed using the mts assay and an annexin v-fitc/pi apoptosis detection kit, respectively. |
2021-10-01 |
2023-08-13 |
mouse |
| Aykut Özgür, Altan Kara, Nazan Gökşen Tosun, Şaban Tekin, İsa Gökç. Debio-0932, a second generation oral Hsp90 inhibitor, induces apoptosis in MCF-7 and MDA-MB-231 cell lines. Molecular biology reports. vol 48. issue 4. 2021-09-29. PMID:33999319. |
apoptosis inducer role of debio-0932 was evaluated in mcf-7 and mda-mb-231 cells with fluorometric apoptosis/necrosis detection kit. |
2021-09-29 |
2023-08-13 |
Not clear |
| Dijun Ou, Wenbin Ding, Changjun Tong, Weihong Y. Knockdown of Long Non-coding RNA LINC00473 Protects CHON-001 Cells against Interleukin-1β-Induced Cell Injury. Biological & pharmaceutical bulletin. vol 44. issue 2. 2021-09-27. PMID:33268698. |
protein expression, cell apoptosis and cell proliferation of chon-001 cells were investigated by western blot, annexin v and propidium iodide (pi) double staining, cell counting-8 kit assay and immunofluorescence staining respectively. |
2021-09-27 |
2023-08-13 |
human |
| Xuelian Gong, Ling Jiang, Wei Li, Qingbin Liang, Zhen L. Curcumin induces apoptosis and autophagy inhuman renal cell carcinoma cells via Akt/mTOR suppression. Bioengineered. vol 12. issue 1. 2021-09-27. PMID:34402718. |
cell proliferation was determined through mtt assays while apoptosis was investigated using annexin v-fitc/pi kit and flow cytometry. |
2021-09-27 |
2023-08-13 |
mouse |
| Bin Sun, Xiaoxian Liu, Han Peng, Xin Xiang, Hua Yan. Circular RNA _NLRP1 targets mouse microRNA-199b-3p to regulate apoptosis and pyroptosis of hippocampal neuron under oxygen-glucose deprivation exposure. Bioengineered. vol 12. issue 1. 2021-09-22. PMID:34227902. |
after the cell model was pre-treated with short hairpin (sh)-circ_nlrp1 or mmu-mir-199b-3p inhibitor, ldh release and cell apoptosis were detected by ldh kit and tunel staining, respectively, while the expression of nlrp3 pyroptosis-related makers was analyzed through immunofluorescence (if) assay and western blot, respectively. |
2021-09-22 |
2023-08-13 |
mouse |
| Deping Sun, Dongsheng Zh. Circular RNA hsa_circ_0001649 suppresses the growth of osteosarcoma cells via sponging multiple miRNAs. Cell cycle (Georgetown, Tex.). vol 19. issue 20. 2021-09-21. PMID:32954926. |
os cells were stably transfected with pex-circ_0001649 or mirnas mimic, cck-8 kit, colony formation, apoptosis and western blot analysis were used to detect the roles of circ_0001649. |
2021-09-21 |
2023-08-13 |
Not clear |
| Qing An, Zipeng Zhou, Yi Xie, Yu Sun, Haixiang Zhang, Yang Ca. Knockdown of long non-coding RNA NEAT1 relieves the inflammatory response of spinal cord injury through targeting miR-211-5p/MAPK1 axis. Bioengineered. vol 12. issue 1. 2021-09-21. PMID:34151707. |
cell counting kit 8 and flow cytometry assays were used to separately determine the cell viability and apoptosis rate. |
2021-09-21 |
2023-08-13 |
Not clear |
| Yong Zheng, Yan Wang, Rongkang Mai, Liang Liu, Zifeng Zhu, Yiyao Ca. Circ_0007534 Silencing Inhibits the Proliferation, Migration and Invasion and Induces the Apoptosis of Glioma Cells Partly Through Down-Regulating PROX1 Via Elevating miR-22-3p Level. Cellular and molecular neurobiology. 2021-09-18. PMID:34536179. |
cell apoptosis was assessed through measuring the activity of caspase-3 using the caspase-3 kit and the apoptosis rate using flow cytometry. |
2021-09-18 |
2023-08-13 |
Not clear |
| Shanshan Wang, Rilu Feng, Ying Shi, Dexi Chen, Honglei Weng, Huiguo Ding, Chenguang Zhan. Intracellular alpha-fetoprotein interferes with all-trans retinoic acid induced ATG7 expression and autophagy in hepatocellular carcinoma cells. Scientific reports. vol 11. issue 1. 2021-09-16. PMID:33495541. |
cell apoptosis and viability were analyzed by caspase-3 activity, tdt-mediated dutp nick end labeling (tunel) assay, and cell counting kit (cck)-8, respectively. |
2021-09-16 |
2023-08-13 |
Not clear |
| Yunxia Fu, Chunyan Qiu, Yanjun Yang, Jianying Lu, Yun Q. CircLPAR3 Acts as an Oncogene in Oral Squamous Cell Carcinoma Through Regulating the miR-643/HMGB2 Network. Biochemical genetics. 2021-09-16. PMID:34528144. |
cell proliferation, apoptosis, metastasis and stemness were assessed using cell counting kit 8 assay, colony-formation assay, flow cytometry, transwell assay and sphere formation assay. |
2021-09-16 |
2023-08-13 |
Not clear |
| Ling Yang, Lijuan Wang, Juan Wang, Ping Li. Long non-coding RNA Gm11974 aggravates oxygen-glucose deprivation-induced injury via miR-122-5p/SEMA3A axis in ischaemic stroke. Metabolic brain disease. vol 36. issue 7. 2021-09-14. PMID:34338972. |
cell viability and apoptosis were determined by 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-h-tetrazolium bromide (mtt) assay, caspase-3 assay kit and flow cytometry. |
2021-09-14 |
2023-08-13 |
mouse |
| Shuqi Meng, Xiaotong Sun, Zhaodong Juan, Mingling Wang, Ruoguo Wang, Lina Sun, Yaozu Li, Anran Xin, Shuping Li, Yao L. Clemastine Fumarate Attenuates Myocardial Ischemia Reperfusion Injury Through Inhibition of Mast Cell Degranulation. Frontiers in pharmacology. vol 12. 2021-09-14. PMID:34512339. |
apoptosis of h9c2 cells was detected by cck-8, the ldh cytotoxicity assay kit (ldh), tunel staining, and protein expression of bax and bcl-2. |
2021-09-14 |
2023-08-13 |
rat |
| Niloufar Targhazeh, Bahman Yousefi, Samira Asghari, Reza Mohammadnejhad, Parinaz Mansouri, Amir Valizade. MiR-622 acts as a tumor suppressor to induce cell apoptosis and inhibit metastasis in human prostate cancer. Andrologia. vol 53. issue 9. 2021-09-13. PMID:34231241. |
apoptosis was detected using an elisa cell death assay kit. |
2021-09-13 |
2023-08-13 |
human |
| Douglas B Snider, Greer K Arthur, Guido H Falduto, Ana Olivera, Lauren C Ehrhardt-Humbert, Emmaline Smith, Cierra Smith, Dean D Metcalfe, Glenn Crus. Targeting KIT by frameshifting mRNA transcripts as a therapeutic strategy for aggressive mast cell neoplasms. Molecular therapy : the journal of the American Society of Gene Therapy. 2021-09-11. PMID:34371183. |
the result of this alternate approach results in marked downregulation of kit expression, diminished kit signaling, inhibition of mc proliferation, and rapid induction of apoptosis in neoplastic hmc-1.2 mcs. |
2021-09-11 |
2023-08-13 |
Not clear |
| Chunlai Shi, Xuan Li, Fei Hong, Xueyan Wang, Tingting Jiang, Bingbing Sun, Shuang L. Latent-transforming growth factor β-binding protein 2 accelerates cardiac fibroblast apoptosis by regulating the expression and activity of caspase-3. Experimental and therapeutic medicine. vol 22. issue 4. 2021-09-11. PMID:34504591. |
caspase-3 activity was therefore determined using a caspase-3 assay kit, cck8 was used to determine the rate of cell proliferation and apoptosis rates were quantified using a cell death detection elisa kit. |
2021-09-11 |
2023-08-13 |
mouse |
| Bum Jun Kim, Yoo Jin Kim, Sung-Hwa Sohn, Bohyun Kim, Hee Jung Sul, Hyeong Su Kim, Dae Young Zan. Tivantinib inhibits the VEGF signaling pathway and induces apoptosis in gastric cancer cells with c-MET or VEGFA amplification. Investigational new drugs. vol 38. issue 6. 2021-09-10. PMID:32361789. |
to examine the inhibitory effect of tivantinib on gc cells, we conducted apoptosis analysis using an annexin v-apc/pi apoptosis detection kit and trans-well migration assay with human gc cell lines. |
2021-09-10 |
2023-08-13 |
human |
| Yanhui Zhu, Chengwei Zou, Yanting Jia, Haizhou Zhang, Xiaochun Ma, Jun Zhan. Knockdown of circular RNA circMAT2B reduces oxygen-glucose deprivation-induced inflammatory injury in H9c2 cells through up-regulating miR-133. Cell cycle (Georgetown, Tex.). vol 19. issue 20. 2021-09-09. PMID:32897801. |
cell activity, apoptosis, ros generation and release of inflammatory factors were assessed by cck-8, flow cytometry, ros species assay kit and elisa, respectively. |
2021-09-09 |
2023-08-13 |
Not clear |
| David C Plachetzki, M Sabrina Pankey, Matthew D MacManes, Michael P Lesser, Charles W Walke. The Genome of the Softshell Clam Mya arenaria and the Evolution of Apoptosis. Genome biology and evolution. vol 12. issue 10. 2021-09-08. PMID:32653903. |
our results challenge the current understanding of the evolution of apoptosis and highlight the ancestral complexity of the bilaterian apoptotic tool kit and its subsequent dismantlement during the ecdysozoan radiation. |
2021-09-08 |
2023-08-13 |
Not clear |
| Shican Zhou, Hang Wu, Wenjuan Ning, Xiao Wu, Xiaoxiao Xu, Yuanqiao Ma, Xingwang Li, Junhong Hu, Chenyu Wang, Junpeng Wan. Ivermectin has New Application in Inhibiting Colorectal Cancer Cell Growth. Frontiers in pharmacology. vol 12. 2021-09-07. PMID:34483925. |
we used cck-8 assay to determine the cell viability, used an optical microscope to measure cell morphology, used annexin v-fitc/7-aad kit to determine cell apoptosis, used caspase 3/7 activity apoptosis assay kit to evaluate caspase 3/7 activity, used western blot to determine apoptosis-associated protein expression, and used flow cytometry and fluorescence microscope to determine the reactive oxygen species (ros) levels and cell cycle. |
2021-09-07 |
2023-08-13 |
human |