| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Li Wu, Xiao Liu, Ke Xin Cao, Zi Hui Ni, Wei Dong Li, Zhi Peng Che. Synergistic antitumor effects of rhein and doxorubicin in hepatocellular carcinoma cells. Journal of cellular biochemistry. vol 121. issue 10. 2021-07-12. PMID:30378155. |
cell apoptosis was detected by the annexin v-fitc/pi apoptosis kit. |
2021-07-12 |
2023-08-13 |
Not clear |
| Bao-Li Xiang, Jing Su, Yang Li. [Circ_0001666 promotes the proliferation and inhibits apoptosis of non-small cell lung cancer cells by targeting the miR-330-5p/HMGA2 axis]. Sheng li xue bao : [Acta physiologica Sinica]. vol 73. issue 3. 2021-07-08. PMID:34230950. |
cell counting kit-8 (cck-8) and annexin v-fitc apoptosis detection kit were respectively used to assess the cell proliferation and apoptosis, where circ_0001666 was knockdown in nsclc cells. |
2021-07-08 |
2023-08-13 |
Not clear |
| Chao Yue, Chen Yu, Rui Peng, Jian Wang, Gang Li, Lin X. LINC00665/miR-379-5p/GRP78 regulates cisplatin sensitivity in gastric cancer by modulating endoplasmic reticulum stress. Cytotechnology. vol 73. issue 3. 2021-06-22. PMID:34149174. |
cell counting kit 8 (cck-8) assay and flow cytometry assay respectively determine the proliferative ability and apoptosis of gc cells. |
2021-06-22 |
2023-08-13 |
Not clear |
| Roghayeh Kamran Samani, Mohamad Bagher Tavakoli, Fatemeh Maghsoudinia, Hasan Motaghi, Seyed Hossein Hejazi, Masoud A Mehrgard. Trastuzumab and folic acid functionalized gold nanoclusters as a dual-targeted radiosensitizer for megavoltage radiation therapy of human breast cancer. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. vol 153. 2021-06-21. PMID:32707173. |
also, apoptosis was evaluated using an annexin v-fitc/propidium iodide (pi) kit in flow cytometry. |
2021-06-21 |
2023-08-13 |
human |
| Yue Zhou, Lian-Jun Cai, Li-Hui Xu, Yu Guo, Nuo Chen, Qing Ya. The role of sirt1 in the retinal ganglion cells cultured by high glucose. International ophthalmology. vol 41. issue 3. 2021-06-18. PMID:33174070. |
after 48 h of infection, the viability of rgc was detected by cck8 kit, the apoptosis rate was detected by fcm analysis, and the protein expression of p53, foxo3a, nf-κ b, caspase-3 was detected by western blot. |
2021-06-18 |
2023-08-13 |
Not clear |
| Zhuoqun Huang, Xiafei Yu, Xingyu Liu, Kang Ma, Minghua Huang, Fangfang Li, Wei Yang, Jianguo Ni. Protective effect of transient receptor potential melastatin 2 inhibitor A10 on oxygen glucose deprivation/reperfusion model. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences. vol 50. issue 1. 2021-06-15. PMID:34117854. |
the cell survival rate was detected by cell counting kit 8 （cck-8）; the level of cellular reactive oxygen species （ros） was detected by reactive oxygen detection kit; the mitochondrial membrane potential was detected by tetramethylrhodamine （tmrm） method; the number of apoptotic cells was detected by tunel apoptosis assay kit; the protein expression level of cleaved caspase 3 was detected by western blot．:compared with 3，20，30，50， has lower cytotoxicity and better inhibition effect on channel activity. |
2021-06-15 |
2023-08-13 |
human |
| Jianmin Liu, Ying Gu. Study on mechanism of down-regulating ikca1 molecule affecting the increment of oral squamous cell carcinoma. Cellular and molecular biology (Noisy-le-Grand, France). vol 66. issue 5. 2021-06-03. PMID:33040815. |
apoptosis was detected by membrane linked protein v-fitc/propidium iodide (pi) double-staining apoptosis detection kit. |
2021-06-03 |
2023-08-13 |
human |
| Wen Jin, Liang Chen, Fengyun Gao, Mei Yang, Yan Liu, Bo Wan. Down-regulation of miR-556-3p inhibits hemangioma cell proliferation and promotes apoptosis by targeting VEGFC. Cellular and molecular biology (Noisy-le-Grand, France). vol 66. issue 5. 2021-06-03. PMID:33040837. |
apoptosis was assayed with fitc annexin v apoptosis assay kit. |
2021-06-03 |
2023-08-13 |
Not clear |
| Fangfang Zhao, Guohe Feng, Junyao Zhu, Zhijun Su, Ruyi Guo, Jiangfu Liu, Huatang Zhang, Yongzhen Zha. 3-Methyladenine-enhanced susceptibility to sorafenib in hepatocellular carcinoma cells by inhibiting autophagy. Anti-cancer drugs. vol 32. issue 4. 2021-06-03. PMID:33395067. |
first, by performing cell counting kit 8 cell viability assay, hoechst 33342 apoptosis staining, and annexin v-fluorescein isothiocyanate/propidium iodide apoptosis kit detection, we found that both sorafenib and 3-ma effectively inhibitted the proliferative activity of hepg2 cells and induced their apoptosis to a certain extent. |
2021-06-03 |
2023-08-13 |
Not clear |
| Weiguo Wang, Jian Xin, Wenming Chen, Lizhong Jing, Peng Zhan. Icariin alleviates hypoxia-induced damage in MC3T3-E1 cells by downregulating TALNEC2. Biotechnology and applied biochemistry. vol 67. issue 6. 2021-06-01. PMID:31845407. |
viability and apoptosis rate were individually tested by cell counting kit-8 and annexin v-fluorescein isothiocyanate/propidium iodide kit untied with flow cytometry. |
2021-06-01 |
2023-08-13 |
Not clear |
| Mohd Firdaus Che Mat, Ezanee Azlina Mohamad Hanif, Nor Azian Abdul Murad, Kamariah Ibrahim, Roslan Harun, Rahman Jama. Silencing of ZFP36L2 increases sensitivity to temozolomide through G2/M cell cycle arrest and BAX mediated apoptosis in GBM cells. Molecular biology reports. vol 48. issue 2. 2021-06-01. PMID:33590411. |
a human apoptosis array kit was used to determine the apoptosis pathway underlying chemosensitisation by sirna against zfp36l2 (sizfp36l2). |
2021-06-01 |
2023-08-13 |
human |
| Jing Wang, Zhichun Dong, Liyin Lou, Lijuan Yang, Jingying Qi. MiR-122 Participates in Oxidative Stress and Apoptosis in STZ-Induced Pancreatic International journal of endocrinology. vol 2021. 2021-06-01. PMID:34054947. |
a tunel cell apoptosis detection kit was used to detect apoptosis. |
2021-06-01 |
2023-08-13 |
cat |
| Yun Liu, Guangquan Zhou, Nenggui X. Effect of Metformin Nanoparticle-Mediated Thioredoxin Interacting Protein Expression on Oxaliplatin-Induced Peripheral Neuralgia. Journal of nanoscience and nanotechnology. vol 20. issue 10. 2021-05-31. PMID:32384961. |
flow cytometry and annexin v-fitc/pi apoptosis detection kit were used to detect the apoptosis of sciatic nerve cells. |
2021-05-31 |
2023-08-13 |
mouse |
| Yidan Yan, Jianmin Xu, Guoxin Ma. Honokiol Suppression of Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Gastric Cancer Cell Biological Activity and Its Mechanism. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2021-05-26. PMID:32862190. |
cell proliferation, apoptosis, and cell cycle were evaluated by cell-counting kit 8 and flow cytometry assays. |
2021-05-26 |
2023-08-13 |
human |
| Taniya Sangtitanu, Papassara Sangtanoo, Piroonporn Srimongkol, Tanatorn Saisavoey, Onrapak Reamtong, Aphichart Karnchanata. Peptides obtained from edible mushrooms: Hericium erinaceus offers the ability to scavenge free radicals and induce apoptosis in lung cancer cells in humans. Food & function. vol 11. issue 6. 2021-05-25. PMID:32432266. |
the f4 sub-fraction was also demonstrated to induce apoptosis, as indicated using the fitc annexin v apoptosis detection kit with pi. |
2021-05-25 |
2023-08-13 |
human |
| Yang Liu, Zhu Yaozu, Huang Zhao, Peng Peng, Zhang Tingbao, Chen Jinca. Inhibition of Glioma Cell Growth and Apoptosis Induction through Targeting Wnt10B Expression by Pyrazolo[4,3-c]pyridine-4-one. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2021-05-21. PMID:33173023. |
material and methods the changes in cell growth were analyzed by cell counting kit-8 (cck-8) and apoptosis by flow cytometry using annexin v-fitc staining kit. |
2021-05-21 |
2023-08-13 |
Not clear |
| Xiumei Chen, Yanfang Wang, Lianjun Zhang, Yujun Ga. Hydroxysafflor Yellow A of Carthamus Tinctorius L., Represses the Malignant Development of Esophageal Cancer Cells via Regulating NF-κB Signaling Pathway. Cell biochemistry and biophysics. vol 78. issue 4. 2021-05-19. PMID:32705535. |
then we estimated the actions of hsya on proliferation, invasion and migration, and apoptosis of ec cells using cell counting kit 8, transwell and flow cytometry assays, respectively. |
2021-05-19 |
2023-08-13 |
Not clear |
| Lei Jiao, Yingchun Shao, Qi Yu, Mengmeng Li, Yanying Wang, Manyu Gong, Xuewen Yang, Tianyi Liu, Zhange Li, Heng Liu, Yuanyuan Zhang, Zhongyue Tan, Lihua Sun, Lina Xuan, Hongli Yin, Yong Zhang, Benzhi Cai, Ying Zhang, Baofeng Yan. GDF11 replenishment protects against hypoxia-mediated apoptosis in cardiomyocytes by regulating autophagy. European journal of pharmacology. vol 885. 2021-05-18. PMID:32861661. |
by using the mtt assay, flow cytometry assay, live/dead® viability/cytotoxicity kit stains and tunel assay, we found that exogenous gdf11 decreased apoptosis caused by prolonged hypoxia in cardiomyocytes. |
2021-05-18 |
2023-08-13 |
mouse |
| Xianlan Duan, Lian Zhao, Wancun Jin, Qinxin Xiao, Yani Peng, Gan Huang, Xia Li, Sonia DaSilva-Arnold, Haibo Yu, Zhiguang Zho. MicroRNA-203a regulates pancreatic β cell proliferation and apoptosis by targeting IRS2. Molecular biology reports. vol 47. issue 10. 2021-05-18. PMID:32929654. |
cell proliferation was measured by cell counting kit eight and cell apoptosis was detected using flow cytometry. |
2021-05-18 |
2023-08-13 |
mouse |
| Jie Yang, Wen-Wen Mu, Guo-Yun Li. Synthesis and evaluation of the anticancer activity of bischalcone analogs in human lung carcinoma (A549) cell line. European journal of pharmacology. vol 888. 2021-05-17. PMID:32798508. |
in this study, we synthesized a series of bischalcone analogs via aldol condensation reaction; mtt method was used to evaluate the antiproliferation effects; the 2',7'-dichlorofluorescein fluorescence assay was used to determine the intracellular reactive oxygen species levels; the glutathione reductase-dtnb recycling assay was used to detect the redox imbalance; determination of thiobarbituric acid-reactive substance was used to evaluate the lipid peroxidation; rhodamine 123 was used to test the mitochondrial membrane potential (mmp); the fitc/pi kit was used to detect the apoptosis; western blotting was used to detect the expression of bax and caspase 3. |
2021-05-17 |
2023-08-13 |
human |