| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fangfang Zhao, Guohe Feng, Junyao Zhu, Zhijun Su, Ruyi Guo, Jiangfu Liu, Huatang Zhang, Yongzhen Zha. 3-Methyladenine-enhanced susceptibility to sorafenib in hepatocellular carcinoma cells by inhibiting autophagy. Anti-cancer drugs. vol 32. issue 4. 2021-06-03. PMID:33395067. |
first, by performing cell counting kit 8 cell viability assay, hoechst 33342 apoptosis staining, and annexin v-fluorescein isothiocyanate/propidium iodide apoptosis kit detection, we found that both sorafenib and 3-ma effectively inhibitted the proliferative activity of hepg2 cells and induced their apoptosis to a certain extent. |
2021-06-03 |
2023-08-13 |
Not clear |
| Weiguo Wang, Jian Xin, Wenming Chen, Lizhong Jing, Peng Zhan. Icariin alleviates hypoxia-induced damage in MC3T3-E1 cells by downregulating TALNEC2. Biotechnology and applied biochemistry. vol 67. issue 6. 2021-06-01. PMID:31845407. |
viability and apoptosis rate were individually tested by cell counting kit-8 and annexin v-fluorescein isothiocyanate/propidium iodide kit untied with flow cytometry. |
2021-06-01 |
2023-08-13 |
Not clear |
| Mohd Firdaus Che Mat, Ezanee Azlina Mohamad Hanif, Nor Azian Abdul Murad, Kamariah Ibrahim, Roslan Harun, Rahman Jama. Silencing of ZFP36L2 increases sensitivity to temozolomide through G2/M cell cycle arrest and BAX mediated apoptosis in GBM cells. Molecular biology reports. vol 48. issue 2. 2021-06-01. PMID:33590411. |
a human apoptosis array kit was used to determine the apoptosis pathway underlying chemosensitisation by sirna against zfp36l2 (sizfp36l2). |
2021-06-01 |
2023-08-13 |
human |
| Jing Wang, Zhichun Dong, Liyin Lou, Lijuan Yang, Jingying Qi. MiR-122 Participates in Oxidative Stress and Apoptosis in STZ-Induced Pancreatic International journal of endocrinology. vol 2021. 2021-06-01. PMID:34054947. |
a tunel cell apoptosis detection kit was used to detect apoptosis. |
2021-06-01 |
2023-08-13 |
cat |
| Yun Liu, Guangquan Zhou, Nenggui X. Effect of Metformin Nanoparticle-Mediated Thioredoxin Interacting Protein Expression on Oxaliplatin-Induced Peripheral Neuralgia. Journal of nanoscience and nanotechnology. vol 20. issue 10. 2021-05-31. PMID:32384961. |
flow cytometry and annexin v-fitc/pi apoptosis detection kit were used to detect the apoptosis of sciatic nerve cells. |
2021-05-31 |
2023-08-13 |
mouse |
| Yidan Yan, Jianmin Xu, Guoxin Ma. Honokiol Suppression of Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Gastric Cancer Cell Biological Activity and Its Mechanism. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2021-05-26. PMID:32862190. |
cell proliferation, apoptosis, and cell cycle were evaluated by cell-counting kit 8 and flow cytometry assays. |
2021-05-26 |
2023-08-13 |
human |
| Taniya Sangtitanu, Papassara Sangtanoo, Piroonporn Srimongkol, Tanatorn Saisavoey, Onrapak Reamtong, Aphichart Karnchanata. Peptides obtained from edible mushrooms: Hericium erinaceus offers the ability to scavenge free radicals and induce apoptosis in lung cancer cells in humans. Food & function. vol 11. issue 6. 2021-05-25. PMID:32432266. |
the f4 sub-fraction was also demonstrated to induce apoptosis, as indicated using the fitc annexin v apoptosis detection kit with pi. |
2021-05-25 |
2023-08-13 |
human |
| Yang Liu, Zhu Yaozu, Huang Zhao, Peng Peng, Zhang Tingbao, Chen Jinca. Inhibition of Glioma Cell Growth and Apoptosis Induction through Targeting Wnt10B Expression by Pyrazolo[4,3-c]pyridine-4-one. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2021-05-21. PMID:33173023. |
material and methods the changes in cell growth were analyzed by cell counting kit-8 (cck-8) and apoptosis by flow cytometry using annexin v-fitc staining kit. |
2021-05-21 |
2023-08-13 |
Not clear |
| Xiumei Chen, Yanfang Wang, Lianjun Zhang, Yujun Ga. Hydroxysafflor Yellow A of Carthamus Tinctorius L., Represses the Malignant Development of Esophageal Cancer Cells via Regulating NF-κB Signaling Pathway. Cell biochemistry and biophysics. vol 78. issue 4. 2021-05-19. PMID:32705535. |
then we estimated the actions of hsya on proliferation, invasion and migration, and apoptosis of ec cells using cell counting kit 8, transwell and flow cytometry assays, respectively. |
2021-05-19 |
2023-08-13 |
Not clear |
| Lei Jiao, Yingchun Shao, Qi Yu, Mengmeng Li, Yanying Wang, Manyu Gong, Xuewen Yang, Tianyi Liu, Zhange Li, Heng Liu, Yuanyuan Zhang, Zhongyue Tan, Lihua Sun, Lina Xuan, Hongli Yin, Yong Zhang, Benzhi Cai, Ying Zhang, Baofeng Yan. GDF11 replenishment protects against hypoxia-mediated apoptosis in cardiomyocytes by regulating autophagy. European journal of pharmacology. vol 885. 2021-05-18. PMID:32861661. |
by using the mtt assay, flow cytometry assay, live/dead® viability/cytotoxicity kit stains and tunel assay, we found that exogenous gdf11 decreased apoptosis caused by prolonged hypoxia in cardiomyocytes. |
2021-05-18 |
2023-08-13 |
mouse |
| Xianlan Duan, Lian Zhao, Wancun Jin, Qinxin Xiao, Yani Peng, Gan Huang, Xia Li, Sonia DaSilva-Arnold, Haibo Yu, Zhiguang Zho. MicroRNA-203a regulates pancreatic β cell proliferation and apoptosis by targeting IRS2. Molecular biology reports. vol 47. issue 10. 2021-05-18. PMID:32929654. |
cell proliferation was measured by cell counting kit eight and cell apoptosis was detected using flow cytometry. |
2021-05-18 |
2023-08-13 |
mouse |
| Jie Yang, Wen-Wen Mu, Guo-Yun Li. Synthesis and evaluation of the anticancer activity of bischalcone analogs in human lung carcinoma (A549) cell line. European journal of pharmacology. vol 888. 2021-05-17. PMID:32798508. |
in this study, we synthesized a series of bischalcone analogs via aldol condensation reaction; mtt method was used to evaluate the antiproliferation effects; the 2',7'-dichlorofluorescein fluorescence assay was used to determine the intracellular reactive oxygen species levels; the glutathione reductase-dtnb recycling assay was used to detect the redox imbalance; determination of thiobarbituric acid-reactive substance was used to evaluate the lipid peroxidation; rhodamine 123 was used to test the mitochondrial membrane potential (mmp); the fitc/pi kit was used to detect the apoptosis; western blotting was used to detect the expression of bax and caspase 3. |
2021-05-17 |
2023-08-13 |
human |
| Xinhui Fang, Yangqiu Bai, Lida Zhang, Songze Din. MicroRNA-665 regulates the proliferation, apoptosis and adhesion of gastric cancer cells by binding to cadherin 3. Oncology letters. vol 21. issue 6. 2021-05-13. PMID:33968210. |
finally, caspase-3 activity assay kit and fitc apoptosis detection kit were used for the determination of apoptosis of gc cells. |
2021-05-13 |
2023-08-13 |
Not clear |
| Lei Zhao, BaoHua Wang, WeiJia Zhang, LiXia Su. Effect of miR-499a-5p on damage of cardiomyocyte induced by hypoxia-reoxygenation via downregulating CD38 protein. Journal of cellular biochemistry. vol 121. issue 2. 2021-05-10. PMID:31452254. |
the activity of lactate dehydrogenase (ldh), apoptosis rate and the expression of mir-499a-5p and cluster of differentiation 38 (cd38) in hypoxia-reoxygenation model cells were detected by ldh cytotoxicity assay kit, flow cytometry, real-time polymerase chain reaction, and western blot analysis, respectively. |
2021-05-10 |
2023-08-13 |
Not clear |
| Yuan Zhou, Yao Ge, Qi Liu, Yun-Xiao Li, Xu Chao, Jian-Jun Guan, Yong-Chang Diwu, Qi Zhan. LncRNA BACE1-AS Promotes Autophagy-Mediated Neuronal Damage Through The miR-214-3p/ATG5 Signalling Axis In Alzheimer's Disease. Neuroscience. vol 455. 2021-05-10. PMID:33197504. |
cell apoptosis, cytotoxicity and ros levels were estimated using flow cytometry, an ldh kit and a dcfh-da assay, respectively. |
2021-05-10 |
2023-08-13 |
mouse |
| Quanxin Wu, Cheng Xu, Xianghua Zeng, Zhimin Zhang, Bo Yang, Zhiguo Ra. Tumor suppressor role of sFRP‑4 in hepatocellular carcinoma via the Wnt/β‑catenin signaling pathway. Molecular medicine reports. vol 23. issue 5. 2021-05-10. PMID:33760186. |
moreover, hcclm3 and huh7 cell proliferation were assessed using the brdu elisa assay kit, and cell apoptosis was measured via flow cytometry. |
2021-05-10 |
2023-08-13 |
Not clear |
| Hao Zhang, Fang Liang, Junmin Yue, Peng Liu, Junyong Wang, Zhaoyang Wang, Hongxing Li, Duo Cheng, Jie Du, Kai Zhang, Peng D. MicroRNA‑137 regulates hypoxia‑mediated migration and epithelial‑mesenchymal transition in prostate cancer by targeting LGR4 via the EGFR/ERK signaling pathway. International journal of oncology. vol 57. issue 2. 2021-05-05. PMID:32626928. |
further results from the cell counting kit‑8, cell death detection elisa plus kit, transwell assay, rt‑qpcr and western blotting assays revealed that the mir‑137 mimic prevented cell proliferation, facilitated apoptosis and repressed cell migration, invasiveness, and expression of n‑cadherin, vimentin and matrix metalloproteinase 2; the mir‑137 inhibitor exerted the opposite effects. |
2021-05-05 |
2023-08-13 |
Not clear |
| Jinwei Wang, Sha Wang, Lu Chen, Jia Ta. SCARA5 suppresses the proliferation and migration, and promotes the apoptosis of human retinoblastoma cells by inhibiting the PI3K/AKT pathway. Molecular medicine reports. vol 23. issue 3. 2021-05-04. PMID:33495818. |
the proliferation, migration and apoptosis of rb cells was then measured by cell counting kit 8 assay, 5‑ethynyl‑2'‑deoxyuridine assay, clone formation assay, transwell assay, hoechst staining and tunel staining, respectively. |
2021-05-04 |
2023-08-13 |
human |
| Yanxia Zhao, Jun Shi, Yankun Zhao, Zhifang L. SNHG1/miR-186/FUT8 regulates cell migration and invasion in oral squamous cell carcinoma. Oral diseases. 2021-05-04. PMID:33872442. |
cell proliferation, apoptosis, migration, and invasion were detected by cck-8 assay, flow cytometry, cell death detection elisa plus kit, and transwell assays. |
2021-05-04 |
2023-08-13 |
Not clear |
| Hongying Xu, Xiaowei Sun, Ying Huang, Qin Si, Maokun L. Long non‑coding RNA NEAT1 modifies cell proliferation, colony formation, apoptosis, migration and invasion via the miR‑4500/BZW1 axis in ovarian cancer. Molecular medicine reports. vol 22. issue 4. 2021-04-30. PMID:32945505. |
furthermore, cell proliferation, colony formation, apoptosis, migration and invasion were assessed using cell‑counting kit 8, colony formation, flow cytometry and transwell assays, respectively. |
2021-04-30 |
2023-08-13 |
Not clear |