| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Nagat. Apoptosis regulated by a death factor and its receptor: Fas ligand and Fas. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 345. issue 1313. 1995-03-03. PMID:7531345. |
our recent studies on the fas ligand and fas indicate that they work respectively as a death factor and its receptor and suggest that, in some cases, cell death or apoptosis is regulated by cytokines and their receptors. |
1995-03-03 |
2023-08-12 |
Not clear |
| Y Shima, N Nishimoto, A Ogata, Y Fujii, K Yoshizaki, T Kishimot. Myeloma cells express Fas antigen/APO-1 (CD95) but only some are sensitive to anti-Fas antibody resulting in apoptosis. Blood. vol 85. issue 3. 1995-03-02. PMID:7530506. |
myeloma cells express fas antigen/apo-1 (cd95) but only some are sensitive to anti-fas antibody resulting in apoptosis. |
1995-03-02 |
2023-08-12 |
Not clear |
| Y Shima, N Nishimoto, A Ogata, Y Fujii, K Yoshizaki, T Kishimot. Myeloma cells express Fas antigen/APO-1 (CD95) but only some are sensitive to anti-Fas antibody resulting in apoptosis. Blood. vol 85. issue 3. 1995-03-02. PMID:7530506. |
the data indicate that only some myeloma cells undergo apoptosis in response to the signal mediated by the fas antigen. |
1995-03-02 |
2023-08-12 |
Not clear |
| J Ogasawara, T Suda, S Nagat. Selective apoptosis of CD4+CD8+ thymocytes by the anti-Fas antibody. The Journal of experimental medicine. vol 181. issue 2. 1995-02-24. PMID:7530758. |
fas is a cell surface protein that mediates apoptosis. |
1995-02-24 |
2023-08-12 |
mouse |
| J Ogasawara, T Suda, S Nagat. Selective apoptosis of CD4+CD8+ thymocytes by the anti-Fas antibody. The Journal of experimental medicine. vol 181. issue 2. 1995-02-24. PMID:7530758. |
when the wild-type thymocytes were treated with the agonistic anti-fas antibody, double positive cells from the wild-type mice were selectively killed by apoptosis, whereas, the single positive cells were resistant to its cytolytic activity despite their abundant expression of fas. |
1995-02-24 |
2023-08-12 |
mouse |
| M A Maldonado, R A Eisenberg, E Roper, P L Cohen, B L Kotzi. Greatly reduced lymphoproliferation in lpr mice lacking major histocompatibility complex class I. The Journal of experimental medicine. vol 181. issue 2. 1995-02-24. PMID:7530760. |
mice homozygous for the lpr gene have a defect in fas (cd95), a cell surface receptor that belongs to the tumor necrosis factor receptor family and that mediates apoptosis. |
1995-02-24 |
2023-08-12 |
mouse |
| T Brunner, R J Mogil, D LaFace, N J Yoo, A Mahboubi, F Echeverri, S J Martin, W R Force, D H Lynch, C F War. Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas. Nature. vol 373. issue 6513. 1995-02-22. PMID:7530336. |
cell-autonomous fas (cd95)/fas-ligand interaction mediates activation-induced apoptosis in t-cell hybridomas. |
1995-02-22 |
2023-08-12 |
Not clear |
| T Takahashi, M Tanaka, J Inazawa, T Abe, T Suda, S Nagat. Human Fas ligand: gene structure, chromosomal location and species specificity. International immunology. vol 6. issue 10. 1995-02-22. PMID:7826947. |
fas ligand (fasl) is a 40 kda type ii membrane protein belonging to the tumor necrosis factor family, which induces apoptosis by binding to its receptor, fas. |
1995-02-22 |
2023-08-12 |
mouse |
| T Takahashi, M Tanaka, J Inazawa, T Abe, T Suda, S Nagat. Human Fas ligand: gene structure, chromosomal location and species specificity. International immunology. vol 6. issue 10. 1995-02-22. PMID:7826947. |
both human and mouse recombinant fasl expressed in cos induced apoptosis in the cells expressing either human fas or mouse fas, indicating that fasl fully cross-reacts between human and mouse. |
1995-02-22 |
2023-08-12 |
mouse |
| E S Sobel, V N Kakkanaiah, R G Rapoport, R A Eisenberg, P L Cohe. The abnormal lpr double-negative T cell fails to proliferate in vivo. Clinical immunology and immunopathology. vol 74. issue 2. 1995-02-21. PMID:7828372. |
the identification of the lpr mutation as a defect in the fas apoptosis receptor gene suggests that dnt accumulation may result from abnormal persistence rather than overproliferation. |
1995-02-21 |
2023-08-12 |
mouse |
| D Watanabe, T Suda, H Hashimoto, S Nagat. Constitutive activation of the Fas ligand gene in mouse lymphoproliferative disorders. The EMBO journal. vol 14. issue 1. 1995-02-17. PMID:7530197. |
the lpr mice have a defect in a cell-surface receptor, fas, that mediates apoptosis, while gld mice have a mutation in the fas ligand (fasl). |
1995-02-17 |
2023-08-12 |
mouse |
| J Cheng, C Liu, W J Koopman, J D Mount. Characterization of human Fas gene. Exon/intron organization and promoter region. Journal of immunology (Baltimore, Md. : 1950). vol 154. issue 3. 1995-02-16. PMID:7529798. |
ligation of the fas cell-surface molecule induces apoptosis. |
1995-02-16 |
2023-08-12 |
mouse |
| Y Oshimi, S Miyazak. Fas antigen-mediated DNA fragmentation and apoptotic morphologic changes are regulated by elevated cytosolic Ca2+ level. Journal of immunology (Baltimore, Md. : 1950). vol 154. issue 2. 1995-02-09. PMID:7529280. |
more than 80% of cells of the human b cell line fmo, which expresses the fas ag, underwent apoptosis within 2 h after addition of an anti-fas mab. |
1995-02-09 |
2023-08-12 |
human |
| M Oishi, K Maeda, S Sugiyam. Distribution of apoptosis-mediating Fas antigen in human skin and effects of anti-Fas monoclonal antibody on human epidermal keratinocyte and squamous cell carcinoma cell lines. Archives of dermatological research. vol 286. issue 7. 1995-02-09. PMID:7529480. |
the cell lines kjd and hsc strongly expressed the fas antigen, and crosslinking of the fas antigen by an anti-fas monoclonal antibody induced apoptosis of these cell lines. |
1995-02-09 |
2023-08-12 |
human |
| J D Mountz, T Zhou, H Bluethmann, J Wu, C K Edward. Apoptosis defects analyzed in TcR transgenic and fas transgenic lpr mice. International reviews of immunology. vol 11. issue 4. 1995-01-30. PMID:7528763. |
apoptosis defects analyzed in tcr transgenic and fas transgenic lpr mice. |
1995-01-30 |
2023-08-12 |
mouse |
| J D Mountz, T Zhou, H Bluethmann, J Wu, C K Edward. Apoptosis defects analyzed in TcR transgenic and fas transgenic lpr mice. International reviews of immunology. vol 11. issue 4. 1995-01-30. PMID:7528763. |
defective expression of the fas apoptosis antigen in mrl-lpr/lpr mice results from the insertion of the etn retrotransposon. |
1995-01-30 |
2023-08-12 |
mouse |
| J M Lahti, J Xiang, L S Heath, D Campana, V J Kid. PITSLRE protein kinase activity is associated with apoptosis. Molecular and cellular biology. vol 15. issue 1. 1995-01-24. PMID:7528324. |
finally, induction of apoptosis by glucocorticoids in the same cell line, as well as by fas mab treatment of another t-cell line, led to a similar induction of 50-kda pitslre protein levels over time. |
1995-01-24 |
2023-08-12 |
human |
| R Ni, Y Tomita, K Matsuda, A Ichihara, K Ishimura, J Ogasawara, S Nagat. Fas-mediated apoptosis in primary cultured mouse hepatocytes. Experimental cell research. vol 215. issue 2. 1995-01-03. PMID:7526995. |
these results indicate that the fas antigen expressed in mouse hepatocytes functionally transduces the apoptotic signal and suggest that cultured mouse hepatocytes express protective proteins against apoptosis and that phosphorylation by pkc is also involved in protection of the hepatocytes from fas-mediated apoptosis. |
1995-01-03 |
2023-08-12 |
mouse |
| B C Richardson, N D Lalwani, K J Johnson, R M Mark. Fas ligation triggers apoptosis in macrophages but not endothelial cells. European journal of immunology. vol 24. issue 11. 1994-12-21. PMID:7525299. |
fas ligation triggers apoptosis in macrophages but not endothelial cells. |
1994-12-21 |
2023-08-12 |
Not clear |
| B C Richardson, N D Lalwani, K J Johnson, R M Mark. Fas ligation triggers apoptosis in macrophages but not endothelial cells. European journal of immunology. vol 24. issue 11. 1994-12-21. PMID:7525299. |
one mechanism involved in cellular elimination is apoptosis, which can be triggered in some cells by ligation of the fas molecule. |
1994-12-21 |
2023-08-12 |
Not clear |