| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Sayama, S Yonehara, Y Watanabe, Y Mik. Expression of Fas antigen on keratinocytes in vivo and induction of apoptosis in cultured keratinocytes. The Journal of investigative dermatology. vol 103. issue 3. 1994-10-05. PMID:7521376. |
fas antigen, which belongs to a nerve growth factor/tumor necrosis factor receptor superfamily, is a membrane protein that induces apoptosis. |
1994-10-05 |
2023-08-12 |
Not clear |
| K Sayama, S Yonehara, Y Watanabe, Y Mik. Expression of Fas antigen on keratinocytes in vivo and induction of apoptosis in cultured keratinocytes. The Journal of investigative dermatology. vol 103. issue 3. 1994-10-05. PMID:7521376. |
cultured keratinocytes expressing fas antigen increased from 8.4% to 34.6% after stimulation with interferon gamma for 24 h. treatment of interferon-gamma-stimulated keratinocytes with anti-fas for 48 h resulted in dna fragmentation and death of 32% of cells, suggesting that fas antigen may mediate apoptosis. |
1994-10-05 |
2023-08-12 |
Not clear |
| J F Zagury, H Cantalloube, A Achour, Y Y Cho, L Fall, A Lachgar, V Chams, A Astgen, D Biou, O Picar. Striking similarities between HIV-1 Env protein and the apoptosis mediating cell surface antigen Fas. Role in the pathogenesis of AIDS. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 47. issue 8. 1994-09-21. PMID:7520296. |
striking similarities between hiv-1 env protein and the apoptosis mediating cell surface antigen fas. |
1994-09-21 |
2023-08-12 |
Not clear |
| M Tanaka, H Ito, S Adachi, H Akimoto, T Nishikawa, T Kasajima, F Marumo, M Hiro. Hypoxia induces apoptosis with enhanced expression of Fas antigen messenger RNA in cultured neonatal rat cardiomyocytes. Circulation research. vol 75. issue 3. 1994-09-20. PMID:7520371. |
hypoxia induces apoptosis with enhanced expression of fas antigen messenger rna in cultured neonatal rat cardiomyocytes. |
1994-09-20 |
2023-08-12 |
rat |
| M Tanaka, H Ito, S Adachi, H Akimoto, T Nishikawa, T Kasajima, F Marumo, M Hiro. Hypoxia induces apoptosis with enhanced expression of Fas antigen messenger RNA in cultured neonatal rat cardiomyocytes. Circulation research. vol 75. issue 3. 1994-09-20. PMID:7520371. |
these results indicate that cardiomyocyte death by hypoxia can occur via apoptosis and that fas antigen may be associated with the mechanism of this apoptotic process. |
1994-09-20 |
2023-08-12 |
rat |
| E Kondo, T Yoshino, I Yamadori, Y Matsuo, N Kawasaki, J Minowada, T Akag. Expression of Bcl-2 protein and Fas antigen in non-Hodgkin's lymphomas. The American journal of pathology. vol 145. issue 2. 1994-09-08. PMID:7519826. |
thus, follicular lymphomas may have a growth advantage due to their high expression of bcl-2 protein, which tended to impede apoptosis mediated by fas antigen. |
1994-09-08 |
2023-08-12 |
Not clear |
| E Kondo, T Yoshino, I Yamadori, Y Matsuo, N Kawasaki, J Minowada, T Akag. Expression of Bcl-2 protein and Fas antigen in non-Hodgkin's lymphomas. The American journal of pathology. vol 145. issue 2. 1994-09-08. PMID:7519826. |
cytocidal assay of seven leukemia/lymphoma cell lines using anti-human fas monoclonal antibody revealed that overexpression of bcl-2 protein tended to impede apoptosis mediated by fas antigen. |
1994-09-08 |
2023-08-12 |
Not clear |
| K Iwai, T Miyawaki, T Takizawa, A Konno, K Ohta, A Yachie, H Seki, N Taniguch. Differential expression of bcl-2 and susceptibility to anti-Fas-mediated cell death in peripheral blood lymphocytes, monocytes, and neutrophils. Blood. vol 84. issue 4. 1994-09-07. PMID:7519477. |
the recently identified fas antigen (ag) is a cell surface molecule that can mediate apoptosis. |
1994-09-07 |
2023-08-12 |
Not clear |
| C M Eischen, C J Dick, P J Leibso. Tyrosine kinase activation provides an early and requisite signal for Fas-induced apoptosis. Journal of immunology (Baltimore, Md. : 1950). vol 153. issue 5. 1994-09-06. PMID:7519637. |
the apoptosis induced by ligation of the fas ag, a member of the tnfr/nerve growth factor receptor superfamily, contributes to both of these modes of cell loss. |
1994-09-06 |
2023-08-12 |
Not clear |
| A D Steinber. Systemic lupus erythematosus: theories of pathogenesis and approach to therapy. Clinical immunology and immunopathology. vol 72. issue 2. 1994-09-02. PMID:8050189. |
the normal fas cell surface molecule is important in programmed cell death, apoptosis. |
1994-09-02 |
2023-08-12 |
mouse |
| A D Steinber. Systemic lupus erythematosus: theories of pathogenesis and approach to therapy. Clinical immunology and immunopathology. vol 72. issue 2. 1994-09-02. PMID:8050189. |
the lpr-associated defect in fas interferes with normal apoptosis, allowing persistence of self-reactive lymphocytes. |
1994-09-02 |
2023-08-12 |
mouse |
| b' H Arase, N Arase, Y Kobayashi, Y Nishimura, S Yonehara, K Ono\\xc3\\xa. Cytotoxicity of fresh NK1.1+ T cell receptor alpha/beta+ thymocytes against a CD4+8+ thymocyte population associated with intact Fas antigen expression on the target. The Journal of experimental medicine. vol 180. issue 2. 1994-08-30. PMID:7519236.' |
however, only weak cytotoxicity was detected against thymocytes from lpr mice on which the fas antigen that transduces signals for apoptosis into the cells is not expressed. |
1994-08-30 |
2023-08-12 |
mouse |
| Z Q Wang, A Dudhane, T Orlikowsky, K Clarke, X Li, Z Darzynkiewicz, M K Hoffman. CD4 engagement induces Fas antigen-dependent apoptosis of T cells in vivo. European journal of immunology. vol 24. issue 7. 1994-08-09. PMID:7517874. |
cd4 engagement induces fas antigen-dependent apoptosis of t cells in vivo. |
1994-08-09 |
2023-08-12 |
mouse |
| N Hiramatsu, N Hayashi, K Katayama, K Mochizuki, Y Kawanishi, A Kasahara, H Fusamoto, T Kamad. Immunohistochemical detection of Fas antigen in liver tissue of patients with chronic hepatitis C. Hepatology (Baltimore, Md.). vol 19. issue 6. 1994-06-22. PMID:7514559. |
immunohistochemical detection of fas antigen in liver tissue of patients with chronic hepatitis c. apoptosis is a type of cell death that occurs in acute or chronic hepatitis. |
1994-06-22 |
2023-08-12 |
Not clear |
| N Hiramatsu, N Hayashi, K Katayama, K Mochizuki, Y Kawanishi, A Kasahara, H Fusamoto, T Kamad. Immunohistochemical detection of Fas antigen in liver tissue of patients with chronic hepatitis C. Hepatology (Baltimore, Md.). vol 19. issue 6. 1994-06-22. PMID:7514559. |
to evaluate the role of apoptosis on liver injury of chronic hepatitis c, we studied the expressions of fas antigen and hepatitis c virus antigen (core antigen) immunohistochemically. |
1994-06-22 |
2023-08-12 |
Not clear |
| N Hiramatsu, N Hayashi, K Katayama, K Mochizuki, Y Kawanishi, A Kasahara, H Fusamoto, T Kamad. Immunohistochemical detection of Fas antigen in liver tissue of patients with chronic hepatitis C. Hepatology (Baltimore, Md.). vol 19. issue 6. 1994-06-22. PMID:7514559. |
our findings suggest that fas antigen expression (apoptosis) plays an important role in inflammation in the hepatitis c virus-infected liver, particularly in the active inflammation of chronic hepatitis c. |
1994-06-22 |
2023-08-12 |
Not clear |
| S T Ju, H Cui, D J Panka, R Ettinger, A Marshak-Rothstei. Participation of target Fas protein in apoptosis pathway induced by CD4+ Th1 and CD8+ cytotoxic T cells. Proceedings of the National Academy of Sciences of the United States of America. vol 91. issue 10. 1994-06-16. PMID:7514297. |
participation of target fas protein in apoptosis pathway induced by cd4+ th1 and cd8+ cytotoxic t cells. |
1994-06-16 |
2023-08-12 |
mouse |
| S T Ju, H Cui, D J Panka, R Ettinger, A Marshak-Rothstei. Participation of target Fas protein in apoptosis pathway induced by CD4+ Th1 and CD8+ cytotoxic T cells. Proceedings of the National Academy of Sciences of the United States of America. vol 91. issue 10. 1994-06-16. PMID:7514297. |
the results presented here provide evidence that the presence of fas protein in target cells is essential to permit cytotoxicity (resulting in apoptosis) mediated by cloned cd4+ th1 cells. |
1994-06-16 |
2023-08-12 |
mouse |
| S T Ju, H Cui, D J Panka, R Ettinger, A Marshak-Rothstei. Participation of target Fas protein in apoptosis pathway induced by CD4+ Th1 and CD8+ cytotoxic T cells. Proceedings of the National Academy of Sciences of the United States of America. vol 91. issue 10. 1994-06-16. PMID:7514297. |
our study demonstrates that cd4+ th1 cells and cd8+ ctls differ in their (ca2+)ext-dependent cytotoxicity but share a (ca2+)ext-independent cytotoxicity that requires participation of fas molecules for cytotoxic signal transduction leading to target apoptosis. |
1994-06-16 |
2023-08-12 |
mouse |
| J A Gonzalo, R Tarazona, H J Schuurman, F Uytdehaag, G Wick, C Martínez, G Kroeme. A single injection of Staphylococcus aureus enterotoxin B reduces autoimmunity in MRL/lpr mice. Clinical immunology and immunopathology. vol 71. issue 2. 1994-06-16. PMID:8181186. |
mrl/mp-lpr/lpr (mrl/lpr) mice carry a mutation in the fas gene whose product is involved in the regulation of lymphocyte apoptosis. |
1994-06-16 |
2023-08-12 |
mouse |