| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B C Richardson, N D Lalwani, K J Johnson, R M Mark. Fas ligation triggers apoptosis in macrophages but not endothelial cells. European journal of immunology. vol 24. issue 11. 1994-12-21. PMID:7525299. |
we demonstrate that macrophages express fas and readily undergo apoptosis when cultured with anti-fas. |
1994-12-21 |
2023-08-12 |
Not clear |
| B C Richardson, N D Lalwani, K J Johnson, R M Mark. Fas ligation triggers apoptosis in macrophages but not endothelial cells. European journal of immunology. vol 24. issue 11. 1994-12-21. PMID:7525299. |
in contrast, while endothelial cells can express the fas molecule, fas ligation is insufficient to induce apoptosis. |
1994-12-21 |
2023-08-12 |
Not clear |
| P Musette, C Pannetier, G Gachelin, P Kourilsk. The expansion of a CD4+ T cell population bearing a distinctive beta chain in MRL lpr/lpr mice suggests a role for the fas protein in peripheral T cell selection. European journal of immunology. vol 24. issue 11. 1994-12-21. PMID:7525303. |
the lpr mutation impairs the normal transcription of the fas message, the product of which mediates apoptosis and presumably the proper selection of t cells. |
1994-12-21 |
2023-08-12 |
mouse |
| L M Rose, D S Latchman, D A Isenber. Bcl-2 and Fas, molecules which influence apoptosis. A possible role in systemic lupus erythematosus? Autoimmunity. vol 17. issue 4. 1994-12-13. PMID:7524704. |
bcl-2 and fas, molecules which influence apoptosis. |
1994-12-13 |
2023-08-12 |
mouse |
| L M Rose, D S Latchman, D A Isenber. Bcl-2 and Fas, molecules which influence apoptosis. A possible role in systemic lupus erythematosus? Autoimmunity. vol 17. issue 4. 1994-12-13. PMID:7524704. |
these are bcl-2 which enhances cell survival by inhibiting or delaying apoptosis and fas, a cell surface molecule involved in the induction of apoptosis. |
1994-12-13 |
2023-08-12 |
mouse |
| E Mita, N Hayashi, S Iio, T Takehara, T Hijioka, A Kasahara, H Fusamoto, T Kamad. Role of Fas ligand in apoptosis induced by hepatitis C virus infection. Biochemical and biophysical research communications. vol 204. issue 2. 1994-11-30. PMID:7980502. |
role of fas ligand in apoptosis induced by hepatitis c virus infection. |
1994-11-30 |
2023-08-12 |
mouse |
| E Mita, N Hayashi, S Iio, T Takehara, T Hijioka, A Kasahara, H Fusamoto, T Kamad. Role of Fas ligand in apoptosis induced by hepatitis C virus infection. Biochemical and biophysical research communications. vol 204. issue 2. 1994-11-30. PMID:7980502. |
to investigate the role that fas ligand plays in the apoptosis of hepatocytes induced by hepatitis c virus infection, we isolated a cdna clone for human fas ligand and examined the expression of fas ligand in liver-infiltrating mononuclear cells obtained from patients with chronic hepatitis c. the amino acid sequence of human fas ligand showed 76% and 77% identity with those of rat and mouse fas ligand, respectively. |
1994-11-30 |
2023-08-12 |
mouse |
| J D Mountz, J Wu, J Cheng, T Zho. Autoimmune disease. A problem of defective apoptosis. Arthritis and rheumatism. vol 37. issue 10. 1994-11-14. PMID:7524507. |
patients with sle have increased levels of soluble fas that inhibit proper apoptosis of lymphocytes. |
1994-11-14 |
2023-08-12 |
human |
| J D Mountz, J Wu, J Cheng, T Zho. Autoimmune disease. A problem of defective apoptosis. Arthritis and rheumatism. vol 37. issue 10. 1994-11-14. PMID:7524507. |
in animal models of autoimmune diseases, mutations of genes involved in apoptosis including fas, fas ligand, and the hematopoietic cell phosphatase gene have been identified. |
1994-11-14 |
2023-08-12 |
human |
| Y Aoki, K Hiromatsu, J Usami, M Makino, H Igarashi, J Ogasawara, S Nagata, Y Yoshika. Clonal expansion but lack of subsequent clonal deletion of bacterial superantigen-reactive T cells in murine retroviral infection. Journal of immunology (Baltimore, Md. : 1950). vol 153. issue 8. 1994-11-10. PMID:7523498. |
these findings suggest that activation-induced apoptosis of superantigen-reactive cd4+ t cells is interfered with in vivo during the course of maids, which is not attributable to underexpression of the fas ag by the cd4+ t cells. |
1994-11-10 |
2023-08-12 |
mouse |
| N Oyaizu, T W McCloskey, S Than, R Hu, V S Kalyanaraman, S Pahw. Cross-linking of CD4 molecules upregulates Fas antigen expression in lymphocytes by inducing interferon-gamma and tumor necrosis factor-alpha secretion. Blood. vol 84. issue 8. 1994-11-09. PMID:7522637. |
both inf-gamma and tnf-alpha were found to contribute to fas ag upregulation and both anti-ifn-gamma and anti-tnf-alpha antibodies blocked cd4xl-induced fas ag upregulation and lymphocyte apoptosis. |
1994-11-09 |
2023-08-12 |
human |
| N Oyaizu, T W McCloskey, S Than, R Hu, V S Kalyanaraman, S Pahw. Cross-linking of CD4 molecules upregulates Fas antigen expression in lymphocytes by inducing interferon-gamma and tumor necrosis factor-alpha secretion. Blood. vol 84. issue 8. 1994-11-09. PMID:7522637. |
these findings strongly suggest that aberrant cytokine secretion induced by cd4xl and consequent upregulation of fas ag expression might play a critical role in triggering peripheral t-cell apoptosis and thereby contribute to hiv disease pathogenesis. |
1994-11-09 |
2023-08-12 |
human |
| K Hiromatsu, Y Aoki, M Makino, Y Matsumoto, T Mizuochi, Y Gotoh, K Nomoto, J Ogasawara, S Nagata, Y Yoshika. Increased Fas antigen expression in murine retrovirus-induced immunodeficiency syndrome, MAIDS. European journal of immunology. vol 24. issue 10. 1994-11-07. PMID:7523140. |
the fas antigen (fas), which is a cell surface protein belonging to the tumor necrosis factor receptor family, mediates apoptosis. |
1994-11-07 |
2023-08-12 |
mouse |
| A Anel, M Buferne, C Boyer, A M Schmitt-Verhulst, P Golstei. T cell receptor-induced Fas ligand expression in cytotoxic T lymphocyte clones is blocked by protein tyrosine kinase inhibitors and cyclosporin A. European journal of immunology. vol 24. issue 10. 1994-11-07. PMID:7523141. |
t cell receptor-induced fas ligand expression in cytotoxic t lymphocyte clones is blocked by protein tyrosine kinase inhibitors and cyclosporin a. fas/apo-1 is a member of the tumor necrosis factor receptor family of proteins that induces apoptosis when cross-linked with monoclonal antibody (mab) or with its physiological ligand. |
1994-11-07 |
2023-08-12 |
Not clear |
| M W Guo, E Mori, J P Xu, T Mor. Identification of Fas antigen associated with apoptotic cell death in murine ovary. Biochemical and biophysical research communications. vol 203. issue 3. 1994-10-31. PMID:7524484. |
in the present study, we detected the expression of the fas antigen (fas), which is a cell-surface protein to modulate apoptosis, in murine ovarian oocytes and hyperovulated eggs as well as in several control tissues. |
1994-10-31 |
2023-08-12 |
Not clear |
| S Izui, R Merino, L Fossati, M Iwamot. The role of the Yaa gene in lupus syndrome. International reviews of immunology. vol 11. issue 3. 1994-10-31. PMID:7930846. |
it is significant that unlike the lpr mutation, whose abnormality is associated with the capacity of the fas antigen to mediate apoptosis, the yaa gene by itself is unable to induce significant autoimmune responses in mice without apparent sle background. |
1994-10-31 |
2023-08-12 |
mouse |
| M Nakanish. [Analysis of Fas antigen gene expression in human thymocytes fractionated with discontinuous gradients using bovine serum albumin]. [Hokkaido igaku zasshi] The Hokkaido journal of medical science. vol 69. issue 3. 1994-10-26. PMID:7523263. |
isolated cdnas encoding fas antigen which mediate apoptosis and is expressed on mouse thymocytes. |
1994-10-26 |
2023-08-12 |
mouse |
| H Hug, M Enari, S Nagat. No requirement of reactive oxygen intermediates in Fas-mediated apoptosis. FEBS letters. vol 351. issue 3. 1994-10-13. PMID:7521851. |
fas is a cell surface molecule that mediates apoptosis, but the intracellular mechanisms leading to apoptosis are not well understood. |
1994-10-13 |
2023-08-12 |
Not clear |
| S K Chiou, C C Tseng, L Rao, E Whit. Functional complementation of the adenovirus E1B 19-kilodalton protein with Bcl-2 in the inhibition of apoptosis in infected cells. Journal of virology. vol 68. issue 10. 1994-10-13. PMID:8083992. |
expression of bcl-2 in hela cells also conferred resistance to apoptosis mediated by tumor necrosis factor alpha and fas antigen, which is also an established function of the e1b 19k protein. |
1994-10-13 |
2023-08-12 |
human |
| K Sayama, S Yonehara, Y Watanabe, Y Mik. Expression of Fas antigen on keratinocytes in vivo and induction of apoptosis in cultured keratinocytes. The Journal of investigative dermatology. vol 103. issue 3. 1994-10-05. PMID:7521376. |
expression of fas antigen on keratinocytes in vivo and induction of apoptosis in cultured keratinocytes. |
1994-10-05 |
2023-08-12 |
Not clear |