| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Nambu, S J Hughes, A Rehemtulla, D Hamstra, M B Orringer, D G Bee. Lack of cell surface Fas/APO-1 expression in pulmonary adenocarcinomas. The Journal of clinical investigation. vol 101. issue 5. 1998-04-09. PMID:9486981. |
parental a549 cells and a549 cells transfected with a fas expression vector were resistant to fas-mediated apoptosis. |
1998-04-09 |
2023-08-12 |
Not clear |
| Y Nambu, S J Hughes, A Rehemtulla, D Hamstra, M B Orringer, D G Bee. Lack of cell surface Fas/APO-1 expression in pulmonary adenocarcinomas. The Journal of clinical investigation. vol 101. issue 5. 1998-04-09. PMID:9486981. |
these findings suggest that the fas protein is reduced or not present on the cell surface in the primary lung tumors and is sequestered within a549 tumorigenic lung cells, and these alterations directly affect the cells resistance to fas-mediated apoptosis. |
1998-04-09 |
2023-08-12 |
Not clear |
| S M Krams, C K Fox, P R Beatty, S Cao, J C Villanueva, C O Esquivel, O M Martine. Human hepatocytes produce an isoform of FAS that inhibits apoptosis. Transplantation. vol 65. issue 5. 1998-04-09. PMID:9521208. |
human hepatocytes produce an isoform of fas that inhibits apoptosis. |
1998-04-09 |
2023-08-12 |
human |
| S M Krams, C K Fox, P R Beatty, S Cao, J C Villanueva, C O Esquivel, O M Martine. Human hepatocytes produce an isoform of FAS that inhibits apoptosis. Transplantation. vol 65. issue 5. 1998-04-09. PMID:9521208. |
fas (apo-1/cd95), a member of the tumor necrosis factor receptor family, can mediate apoptosis when engaged by its ligand or by anti-fas antibody. |
1998-04-09 |
2023-08-12 |
human |
| S M Krams, C K Fox, P R Beatty, S Cao, J C Villanueva, C O Esquivel, O M Martine. Human hepatocytes produce an isoform of FAS that inhibits apoptosis. Transplantation. vol 65. issue 5. 1998-04-09. PMID:9521208. |
the purpose of this study was to determine if soluble variants of fas are produced in the liver and to determine if blockade of the fas pathway, by liver-derived soluble fas, inhibits fas-mediated apoptosis. |
1998-04-09 |
2023-08-12 |
human |
| Catherine A White, Pamela A McCombe, Michael P Pende. The roles of Fas, Fas ligand and Bcl-2 in T cell apoptosis in the central nervous system in experimental autoimmune encephalomyelitis. Journal of neuroimmunology. vol 82. issue 1. 1998-04-09. PMID:9526845. |
the roles of fas, fas ligand and bcl-2 in t cell apoptosis in the central nervous system in experimental autoimmune encephalomyelitis. |
1998-04-09 |
2023-08-12 |
rat |
| Catherine A White, Pamela A McCombe, Michael P Pende. The roles of Fas, Fas ligand and Bcl-2 in T cell apoptosis in the central nervous system in experimental autoimmune encephalomyelitis. Journal of neuroimmunology. vol 82. issue 1. 1998-04-09. PMID:9526845. |
throughout the course of the disease, which peaked 12-14 days after inoculation and was followed by clinical recovery, we analyzed the dna content of the spinal cord inflammatory cells to assess apoptosis and, simultaneously, we measured the expression of five proteins (fas, fas ligand (fas-l), bcl-2, bcl-x and bax) which modulate the apoptotic process. |
1998-04-09 |
2023-08-12 |
rat |
| Catherine A White, Pamela A McCombe, Michael P Pende. The roles of Fas, Fas ligand and Bcl-2 in T cell apoptosis in the central nervous system in experimental autoimmune encephalomyelitis. Journal of neuroimmunology. vol 82. issue 1. 1998-04-09. PMID:9526845. |
cells expressing the death effector molecules fas and fas-l were particularly prone to undergo apoptosis, and were over-represented in the apoptotic population. |
1998-04-09 |
2023-08-12 |
rat |
| Catherine A White, Pamela A McCombe, Michael P Pende. The roles of Fas, Fas ligand and Bcl-2 in T cell apoptosis in the central nervous system in experimental autoimmune encephalomyelitis. Journal of neuroimmunology. vol 82. issue 1. 1998-04-09. PMID:9526845. |
these findings support the hypothesis that autoreactive t cells are eliminated from the cns during spontaneous recovery from eae by activation-induced apoptosis involving the fas pathway. |
1998-04-09 |
2023-08-12 |
rat |
| D E Gutstein, A R Mark. Role of inositol 1,4,5-trisphosphate receptors in regulating apoptotic signaling and heart failure. Heart and vessels. vol Suppl 12. 1998-04-07. PMID:9476544. |
ip3r-deficient t cells are resistant to apoptosis induced by dexamethasone, t cell receptor stimulation, ionizing radiation, and fas. |
1998-04-07 |
2023-08-12 |
human |
| P Chen, J Tian, I Kovesdi, J T Brude. Interaction of the adenovirus 14.7-kDa protein with FLICE inhibits Fas ligand-induced apoptosis. The Journal of biological chemistry. vol 273. issue 10. 1998-04-07. PMID:9488717. |
interaction of the adenovirus 14.7-kda protein with flice inhibits fas ligand-induced apoptosis. |
1998-04-07 |
2023-08-12 |
Not clear |
| P Chen, J Tian, I Kovesdi, J T Brude. Interaction of the adenovirus 14.7-kDa protein with FLICE inhibits Fas ligand-induced apoptosis. The Journal of biological chemistry. vol 273. issue 10. 1998-04-07. PMID:9488717. |
in this report, we demonstrate that infection of cells with an adenovirus vector expressing fas ligand induced rapid apoptosis that was blocked by coinfection with a virus expressing 14. |
1998-04-07 |
2023-08-12 |
Not clear |
| J Zhang, D Cado, A Chen, N H Kabra, A Winot. Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1. Nature. vol 392. issue 6673. 1998-04-06. PMID:9521326. |
a dominant-negative mutant of fadd inhibits apoptosis initiated by fas and other tnfr family members. |
1998-04-06 |
2023-08-12 |
mouse |
| J Zhang, D Cado, A Chen, N H Kabra, A Winot. Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1. Nature. vol 392. issue 6673. 1998-04-06. PMID:9521326. |
fas-induced apoptosis was completely blocked, indicating that there are no redundant fas apoptotic pathways. |
1998-04-06 |
2023-08-12 |
mouse |
| Y Ito, T Takeda, K Umeshita, M Sakon, K Wakasa, N Matsuura, M Monde. Fas antigen expression in hepatocellular carcinoma tissues. Oncology reports. vol 5. issue 1. 1998-04-02. PMID:9458289. |
fas antigen belongs to the tumor necrosis factor receptor family and is known to induce apoptosis. |
1998-04-02 |
2023-08-12 |
Not clear |
| Y Shimaoka, Y Hidaka, M Okumura, K Takeoka, H Tada, N Amin. Serum concentration of soluble Fas in patients with autoimmune thyroid diseases. Thyroid : official journal of the American Thyroid Association. vol 8. issue 1. 1998-04-02. PMID:9492152. |
soluble fas (sfas) molecule lacks the transmembrane domain due to alternative splicing and blocks fas-mediated apoptosis. |
1998-04-02 |
2023-08-12 |
human |
| Y Shimaoka, Y Hidaka, M Okumura, K Takeoka, H Tada, N Amin. Serum concentration of soluble Fas in patients with autoimmune thyroid diseases. Thyroid : official journal of the American Thyroid Association. vol 8. issue 1. 1998-04-02. PMID:9492152. |
increased sfas in graves' disease suggests increased expression of alternatively spliced fas mrna variant that produces sfas protein and decreased of cell surface expression of fas, and may induce thyroid cell growth and production of tsh receptor antibody by protecting against apoptosis of thyroid cells and autoreactive b cells. |
1998-04-02 |
2023-08-12 |
human |
| Y Shimaoka, Y Hidaka, M Okumura, K Takeoka, H Tada, N Amin. Serum concentration of soluble Fas in patients with autoimmune thyroid diseases. Thyroid : official journal of the American Thyroid Association. vol 8. issue 1. 1998-04-02. PMID:9492152. |
decreased sfas in hashimoto's thyroiditis suggests decreased fas mrna variant and increased full-length fas mrna and membrane fas, and may induce destruction of thyroid cells by promoting apoptosis of thyroid cells. |
1998-04-02 |
2023-08-12 |
human |
| L C Foote, A Marshak-Rothstein, T L Rothstei. Tolerant B lymphocytes acquire resistance to Fas-mediated apoptosis after treatment with interleukin 4 but not after treatment with specific antigen unless a surface immunoglobulin threshold is exceeded. The Journal of experimental medicine. vol 187. issue 6. 1998-04-02. PMID:9500787. |
engagement of cd40 led to enhanced fas expression and acquisition of sensitivity to fas-mediated apoptosis in tolerant b cells, similar to that observed in nontolerant, receptor transgenic b cells. |
1998-04-02 |
2023-08-12 |
mouse |
| L C Foote, A Marshak-Rothstein, T L Rothstei. Tolerant B lymphocytes acquire resistance to Fas-mediated apoptosis after treatment with interleukin 4 but not after treatment with specific antigen unless a surface immunoglobulin threshold is exceeded. The Journal of experimental medicine. vol 187. issue 6. 1998-04-02. PMID:9500787. |
thus, tolerant b cells differ from nontolerant b cells in the diminished capacity of surface immunoglobulin engagement to produce fas resistance; however, tolerant b cells can be induced to become resistant to fas-mediated apoptosis by il-4 or by higher order cross-linking of sig receptors. |
1998-04-02 |
2023-08-12 |
mouse |