| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Yang, D Kim, C G Fathma. Regulation of programmed cell death following T cell activation in vivo. International immunology. vol 10. issue 2. 1998-05-06. PMID:9533445. |
cd4+ t cells activated in vivo were resistant to anti-fas-mediated apoptosis until 48 h following staphylococcal enterotoxin b (seb) administration, despite the fact that activated proliferating t cells expressed high levels of fas (cd95) antigen and many 'apoptosis genes' were induced within 24 h of seb administration. |
1998-05-06 |
2023-08-12 |
Not clear |
| Y Kasahara, T Wada, Y Niida, A Yachie, H Seki, Y Ishida, T Sakai, F Koizumi, S Koizumi, T Miyawaki, N Taniguch. Novel Fas (CD95/APO-1) mutations in infants with a lymphoproliferative disorder. International immunology. vol 10. issue 2. 1998-05-06. PMID:9533447. |
in this study, fas-mediated apoptosis and fas mutations were analyzed in three japanese children from two families with a lymphoproliferative disorder characterized by lymphadenopathy, hepatosplenomegaly, pancytopenia, hypergammaglobulinemia and an increase in tcr alphabeta+ cd4- cd8- t cells. |
1998-05-06 |
2023-08-12 |
Not clear |
| M Kitagawa, S Yamaguchi, M Takahashi, T Tanizawa, K Hirokawa, R Kamiyam. Localization of Fas and Fas ligand in bone marrow cells demonstrating myelodysplasia. Leukemia. vol 12. issue 4. 1998-05-04. PMID:9557605. |
to elucidate the mechanism of apoptosis in bone marrow cells of mds, the expression of fas antigen and fas ligand (fasl) was examined by rt-pcr and immunohistochemistry. |
1998-05-04 |
2023-08-12 |
Not clear |
| M Fleck, T Zhou, T Tatsuta, P Yang, Z Wang, J D Mount. Fas/Fas ligand signaling during gestational T cell development. Journal of immunology (Baltimore, Md. : 1950). vol 160. issue 8. 1998-05-04. PMID:9558079. |
most thymocytes express high levels of fas ag (apo-1/cd95); however, the role of fas/fas ligand-mediated apoptosis in thymocyte development remains unclear. |
1998-05-04 |
2023-08-12 |
mouse |
| M Fleck, T Zhou, T Tatsuta, P Yang, Z Wang, J D Mount. Fas/Fas ligand signaling during gestational T cell development. Journal of immunology (Baltimore, Md. : 1950). vol 160. issue 8. 1998-05-04. PMID:9558079. |
thus, early apoptosis correlated with high expression of fas ligand. |
1998-05-04 |
2023-08-12 |
mouse |
| M Fleck, T Zhou, T Tatsuta, P Yang, Z Wang, J D Mount. Fas/Fas ligand signaling during gestational T cell development. Journal of immunology (Baltimore, Md. : 1950). vol 160. issue 8. 1998-05-04. PMID:9558079. |
more mature cd4+cd8+ thymocytes and cd4+ and cd8+ thymocytes became resistant to fas-mediated apoptosis after gd 17, despite high expression of fas. |
1998-05-04 |
2023-08-12 |
mouse |
| M Fleck, T Zhou, T Tatsuta, P Yang, Z Wang, J D Mount. Fas/Fas ligand signaling during gestational T cell development. Journal of immunology (Baltimore, Md. : 1950). vol 160. issue 8. 1998-05-04. PMID:9558079. |
the present results indicate that fas plays a critical role in mediating apoptosis during early gestational thymocyte development and that thymocytes that receive a survival signal through tcr/cd3 become resistant to fas-mediated apoptosis. |
1998-05-04 |
2023-08-12 |
mouse |
| H Fukuyama, M Adachi, S Suematsu, K Miwa, T Suda, N Yoshida, S Nagat. Transgenic expression of Fas in T cells blocks lymphoproliferation but not autoimmune disease in MRL-lpr mice. Journal of immunology (Baltimore, Md. : 1950). vol 160. issue 8. 1998-05-04. PMID:9558084. |
binding of fas ligand to fas induces apoptosis in fas-bearing cells. |
1998-05-04 |
2023-08-12 |
mouse |
| T Suhara, K Fukuo, T Sugimoto, S Morimoto, T Nakahashi, S Hata, M Shimizu, T Ogihar. Hydrogen peroxide induces up-regulation of Fas in human endothelial cells. Journal of immunology (Baltimore, Md. : 1950). vol 160. issue 8. 1998-05-04. PMID:9558114. |
furthermore, a flow cytometric method with propidium iodide staining and electron microscopic analysis showed that incubation with an agonistic ab against fas (anti-fas igm) induced apoptosis in h2o2-treated cells. |
1998-05-04 |
2023-08-12 |
human |
| R Ksontini, D B Colagiovanni, M D Josephs, C K Edwards, C L Tannahill, C C Solorzano, J Norman, W Denham, M Clare-Salzler, S L MacKay, L L Moldawe. Disparate roles for TNF-alpha and Fas ligand in concanavalin A-induced hepatitis. Journal of immunology (Baltimore, Md. : 1950). vol 160. issue 8. 1998-05-04. PMID:9558119. |
in acute inflammation, however, apoptosis triggered by the overproduction of "death factors" such as tnf-alpha or fas ligand (fasl) may contribute to tissue injury. |
1998-05-04 |
2023-08-12 |
mouse |
| F Callera, A B Garcia, R P Falcã. Fas-mediated apoptosis with normal expression of bcl-2 and p53 in lymphocytes from aplastic anaemia. British journal of haematology. vol 100. issue 4. 1998-05-04. PMID:9580207. |
in order to investigate the involvement of apoptosis in the pathogenesis of aplastic anaemia (aa) we measured the expression of the fas receptor (membrane protein that triggers apoptosis), fas ligand (fasl), bcl-2 (cytoplasmatic protein that blocks apoptosis) and p53 (nuclear protein that induces apoptosis) in cd3 and cd19 lymphocytes from the peripheral blood or bone marrow of controls, patients with aa, aplastic anaemia in complete remission (aa-cr) and multiply transfused patients without aplastic anaemia. |
1998-05-04 |
2023-08-12 |
Not clear |
| F Callera, A B Garcia, R P Falcã. Fas-mediated apoptosis with normal expression of bcl-2 and p53 in lymphocytes from aplastic anaemia. British journal of haematology. vol 100. issue 4. 1998-05-04. PMID:9580207. |
to further characterize the functional activity of the fas receptor we performed a fas-induced apoptosis assay in peripheral blood lymphocytes using an anti-fas monoclonal antibody. |
1998-05-04 |
2023-08-12 |
Not clear |
| V Galvan, B Roizma. Herpes simplex virus 1 induces and blocks apoptosis at multiple steps during infection and protects cells from exogenous inducers in a cell-type-dependent manner. Proceedings of the National Academy of Sciences of the United States of America. vol 95. issue 7. 1998-05-01. PMID:9520470. |
we investigated the ability of the virus to protect cells in continuous cultivation from apoptosis induced by the virus itself, and by other known inducers such as exposure to the tumor necrosis factor alpha (tnfalpha), antibody to fas, c2-ceramide, osmotic shock (sorbitol), and thermal shock. |
1998-05-01 |
2023-08-12 |
Not clear |
| A Noble, G A Pestano, H Canto. Suppression of immune responses by CD8 cells. I. Superantigen-activated CD8 cells induce unidirectional Fas-mediated apoptosis of antigen-activated CD4 cells. Journal of immunology (Baltimore, Md. : 1950). vol 160. issue 2. 1998-04-30. PMID:9551888. |
suppression by cd8 cells reflects their ability to induce cd4 cell apoptosis via ligation of fas. |
1998-04-30 |
2023-08-12 |
Not clear |
| A Noble, G A Pestano, H Canto. Suppression of immune responses by CD8 cells. I. Superantigen-activated CD8 cells induce unidirectional Fas-mediated apoptosis of antigen-activated CD4 cells. Journal of immunology (Baltimore, Md. : 1950). vol 160. issue 2. 1998-04-30. PMID:9551888. |
moreover, although activated cd8 cells that express fas ligand and fas eliminate cd4 cells through a fas-dependent mechanism, they are themselves resistant to fas-dependent apoptosis. |
1998-04-30 |
2023-08-12 |
Not clear |
| A Noble, G A Pestano, H Canto. Suppression of immune responses by CD8 cells. I. Superantigen-activated CD8 cells induce unidirectional Fas-mediated apoptosis of antigen-activated CD4 cells. Journal of immunology (Baltimore, Md. : 1950). vol 160. issue 2. 1998-04-30. PMID:9551888. |
these findings indicate a fundamental difference between the two major t cell subsets with regard to sensitivity to fas-dependent apoptosis, expression of fas ligand, and mediation of suppressive activity following immunization with superantigen. |
1998-04-30 |
2023-08-12 |
Not clear |
| J M Lahti, J Xiang, V J Kid. The PITSLRE protein kinase family. Progress in cell cycle research. vol 1. 1998-04-30. PMID:9552375. |
pitslre mrna, protein, and enzyme activity are induced during fas receptor- and glucocorticoid-mediated apoptosis of human t cells. |
1998-04-30 |
2023-08-12 |
human |
| S Spiegel, O Cuvillier, L Edsall, T Kohama, R Menzeleev, A Olivera, D Thomas, Z Tu, J Van Brocklyn, F Wan. Roles of sphingosine-1-phosphate in cell growth, differentiation, and death. Biochemistry. Biokhimiia. vol 63. issue 1. 1998-04-28. PMID:9526097. |
while ceramide has been shown to be an important regulatory component of apoptosis induced by tumor necrosis factor alpha and the fas ligand, sphingosine-1-phosphate (spp), a further metabolite of ceramide, has been implicated as a second messenger in cellular proliferation and survival induced by platelet-derived growth factor, neuronal growth factor, and serum. |
1998-04-28 |
2023-08-12 |
Not clear |
| S C Kim, Y H Min, S Lee, S Y Chung, N C Yoo, J W Lee, J S Hahn, Y W K. Delayed activation-induced T lymphocytes death in aplastic anemia: related with abnormal Fas system. The Korean journal of internal medicine. vol 13. issue 1. 1998-04-28. PMID:9538630. |
to quantitate apoptosis and fas antigen expression of t lymphocytes by activation in aplastic anemia (aa) and compare with that of normal controls and completely-recovered aa, and to investigate the apoptotic sensitivity to anti-fas antibody of activated t lymphocytes in aa. |
1998-04-28 |
2023-08-12 |
Not clear |
| A Hofmann, H M Bla. Death of solid tumor cells induced by Fas ligand expressing primary myoblasts. Somatic cell and molecular genetics. vol 23. issue 4. 1998-04-24. PMID:9542527. |
to test whether the lpr myoblasts expressing fasl could be used in anticancer therapy, human rhabdomyosarcoma derived cell lines were assayed for fas and then tested in the apoptosis coculture assay. |
1998-04-24 |
2023-08-12 |
mouse |