| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Hofmann, H M Bla. Death of solid tumor cells induced by Fas ligand expressing primary myoblasts. Somatic cell and molecular genetics. vol 23. issue 4. 1998-04-24. PMID:9542527. |
these findings together with previous findings suggest that primary myoblasts, defective in fas but genetically engineered to express fasl, could function as potent anticancer agents for use in the localized destruction of solid tumors in vivo by three synergistic mechanisms: (1) directly via fas/fasl mediated apoptosis, (2) indirectly via neutrophil infiltration and immunodestruction, and (3) as allogeneic inducers of a bystander effect via b and t cells. |
1998-04-24 |
2023-08-12 |
mouse |
| H Yoshid. [Induction of apoptosis in murine cytomegalovirus infection]. Nihon rinsho. Japanese journal of clinical medicine. vol 56. issue 1. 1998-04-21. PMID:9465669. |
involvement of tumor necrotic factor-alpha, but not of fas, was suggested in the induction of apoptosis of bone marrow cells. |
1998-04-21 |
2023-08-12 |
mouse |
| W G Telford, S Y Nam, E R Podack, R A Mille. CD30-regulated apoptosis in murine CD8 T cells after cessation of TCR signals. Cellular immunology. vol 182. issue 2. 1998-04-21. PMID:9514701. |
apoptosis induced by agonist withdrawal was not blocked by fas antigen fusion protein or by anti-tnf alpha-neutralizing antibodies, suggesting a mechanism independent of fas/fasl and tnf alpha/tnf-r interactions. |
1998-04-21 |
2023-08-12 |
Not clear |
| R A Salmon, I N Foltz, P R Young, J W Schrade. The p38 mitogen-activated protein kinase is activated by ligation of the T or B lymphocyte antigen receptors, Fas or CD40, but suppression of kinase activity does not inhibit apoptosis induced by antigen receptors. Journal of immunology (Baltimore, Md. : 1950). vol 159. issue 11. 1998-04-20. PMID:9548470. |
the p38 mitogen-activated protein kinase is activated by ligation of the t or b lymphocyte antigen receptors, fas or cd40, but suppression of kinase activity does not inhibit apoptosis induced by antigen receptors. |
1998-04-20 |
2023-08-12 |
mouse |
| R A Salmon, I N Foltz, P R Young, J W Schrade. The p38 mitogen-activated protein kinase is activated by ligation of the T or B lymphocyte antigen receptors, Fas or CD40, but suppression of kinase activity does not inhibit apoptosis induced by antigen receptors. Journal of immunology (Baltimore, Md. : 1950). vol 159. issue 11. 1998-04-20. PMID:9548470. |
we conclude that the activation of p38 mapk and mapkap kinase-2 by cross-linking of the tcr, bcr, fas, or cd40 was not correlated with their roles in regulating lymphocyte survival, and that suppression of kinase activity did not inhibit the induction of apoptosis. |
1998-04-20 |
2023-08-12 |
mouse |
| B Bonetti, J Pohl, Y L Gao, C S Rain. Cell death during autoimmune demyelination: effector but not target cells are eliminated by apoptosis. Journal of immunology (Baltimore, Md. : 1950). vol 159. issue 11. 1998-04-20. PMID:9548518. |
infiltrating cd4+ t cells and parenchymal microglia expressed fas, fasl, and bax, and about half of these cells showed dna fragmentation, a combination indicative of ongoing apoptosis. |
1998-04-20 |
2023-08-12 |
Not clear |
| A Takagi, A Imai, S Horibe, T Ohno, T Tamay. Lack of evidence for expression of Fas ligand in Fas-bearing tumors. Oncology reports. vol 5. issue 2. 1998-04-16. PMID:9468561. |
interaction of fas and its ligand plays an important role in the cell death by means of apoptosis in a variety of cell types. |
1998-04-16 |
2023-08-12 |
human |
| A Takagi, A Imai, S Horibe, T Ohno, T Tamay. Lack of evidence for expression of Fas ligand in Fas-bearing tumors. Oncology reports. vol 5. issue 2. 1998-04-16. PMID:9468561. |
the demonstration of absence of fas ligand expression raises the possibility that the stimulated proliferation of the fas ligand-absent tumors may occurs by release of fas-fas ligand system-associated apoptosis. |
1998-04-16 |
2023-08-12 |
human |
| C Widmann, S Gibson, G L Johnso. Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals. The Journal of biological chemistry. vol 273. issue 12. 1998-04-16. PMID:9507028. |
twenty-two of these proteins were not affected in jurkat cells stimulated to undergo apoptosis by fas ligation, exposure to ultraviolet-c or incubation with etoposide. |
1998-04-16 |
2023-08-12 |
Not clear |
| L Genestier, S Fournel, M Flacher, O Assossou, J P Revillard, N Bonnefoy-Berar. Induction of Fas (Apo-1, CD95)-mediated apoptosis of activated lymphocytes by polyclonal antithymocyte globulins. Blood. vol 91. issue 7. 1998-04-15. PMID:9516135. |
induction of fas (apo-1, cd95)-mediated apoptosis of activated lymphocytes by polyclonal antithymocyte globulins. |
1998-04-15 |
2023-08-12 |
human |
| R E Shadd. Apoptosis in heart transplantation. Coronary artery disease. vol 8. issue 10. 1998-04-14. PMID:9457443. |
the interaction of the cell membrance protein, fas, with its ligand, fas ligand, induces apoptosis in fas-bearing cells. |
1998-04-14 |
2023-08-12 |
Not clear |
| R E Shadd. Apoptosis in heart transplantation. Coronary artery disease. vol 8. issue 10. 1998-04-14. PMID:9457443. |
although studies in the transplanted hearts of rodents and humans have shown the presence of fas, fas ligand, and apoptosis in the myocardium, there is controversy regarding which cells in the myocardium are actually undergoing apoptosis after heart transplantation. |
1998-04-14 |
2023-08-12 |
Not clear |
| K Suzuki, M Nakamura, Y Hatanaka, Y Kayanoki, H Tatsumi, N Taniguch. Induction of apoptotic cell death in human endothelial cells treated with snake venom: implication of intracellular reactive oxygen species and protective effects of glutathione and superoxide dismutases. Journal of biochemistry. vol 122. issue 6. 1998-04-14. PMID:9498574. |
human vascular endothelial cells play a pivotal role in atherosclerotic changes but are resistant to apoptotic inducers such as fas ligand and it has been difficult to induce apoptosis. |
1998-04-14 |
2023-08-12 |
human |
| T Nakashima, H Sasaki, M Tsuboi, A Kawakami, K Fujiyama, T Kiriyama, K Eguchi, M Ichikawa, S Nagatak. Inhibitory effect of glucocorticoid for osteoblast apoptosis induced by activated peripheral blood mononuclear cells. Endocrinology. vol 139. issue 4. 1998-04-14. PMID:9528991. |
fas was functionally expressed on mg63 and primary osteoblast-like cells, and treatment of these cells with dexamethasone affected neither fas expression nor anti-fas igm-induced apoptosis. |
1998-04-14 |
2023-08-12 |
human |
| T Nakashima, H Sasaki, M Tsuboi, A Kawakami, K Fujiyama, T Kiriyama, K Eguchi, M Ichikawa, S Nagatak. Inhibitory effect of glucocorticoid for osteoblast apoptosis induced by activated peripheral blood mononuclear cells. Endocrinology. vol 139. issue 4. 1998-04-14. PMID:9528991. |
activated pbmc expressing membrane-type fas ligand (mfasl) efficiently killed both mg63 and primary osteoblasts-like cells, and the addition of human fas chimeric protein (hfas-fc) significantly diminished the cytotoxicity, indicating that interactions between mfasl of activated pbmc and fas on human osteoblasts induce apoptosis of the latter. |
1998-04-14 |
2023-08-12 |
human |
| A Foghi, A Ravandi, K J Teerds, H Van Der Donk, A Kuksis, J Dorringto. Fas-induced apoptosis in rat thecal/interstitial cells signals through sphingomyelin-ceramide pathway. Endocrinology. vol 139. issue 4. 1998-04-14. PMID:9528992. |
the objective of this study was to determine if activation of the fas receptor could enact apoptosis of thecal cells, and to explore the signal transduction pathway involved. |
1998-04-14 |
2023-08-12 |
rat |
| A Foghi, A Ravandi, K J Teerds, H Van Der Donk, A Kuksis, J Dorringto. Fas-induced apoptosis in rat thecal/interstitial cells signals through sphingomyelin-ceramide pathway. Endocrinology. vol 139. issue 4. 1998-04-14. PMID:9528992. |
in conclusion, the sphingomyelin-ceramide cycle that can lead to cell suicide by apoptosis is functional and activated through the fas ligand/receptor signal transduction pathway, not only in the immune system, but also in thecal/interstitial cells of the ovarian follicle. |
1998-04-14 |
2023-08-12 |
rat |
| D R Meldru. Tumor necrosis factor in the heart. The American journal of physiology. vol 274. issue 3. 1998-04-14. PMID:9530222. |
tnf activation of tnf receptor 1 or fas may induce cardiac myocyte apoptosis. |
1998-04-14 |
2023-08-12 |
Not clear |
| S Hashimoto, R L Ochs, F Rosen, J Quach, G McCabe, J Solan, J E Seegmiller, R Terkeltaub, M Lot. Chondrocyte-derived apoptotic bodies and calcification of articular cartilage. Proceedings of the National Academy of Sciences of the United States of America. vol 95. issue 6. 1998-04-10. PMID:9501221. |
chondrocytes exposed to nitric oxide (no) or antibody to fas undergo cell death by apoptosis. |
1998-04-10 |
2023-08-12 |
Not clear |
| A P Arrig. Small stress proteins: chaperones that act as regulators of intracellular redox state and programmed cell death. Biological chemistry. vol 379. issue 1. 1998-04-10. PMID:9504712. |
(2) shsp protect against apoptosis mediated by different agents including staurosporine, etoposide and the fas ligand. |
1998-04-10 |
2023-08-12 |
Not clear |