| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R De Maria, M R Rippo, E H Schuchman, R Test. Acidic sphingomyelinase (ASM) is necessary for fas-induced GD3 ganglioside accumulation and efficient apoptosis of lymphoid cells. The Journal of experimental medicine. vol 187. issue 6. 1998-04-02. PMID:9500792. |
277:1652-1655), and display a substantially inefficient apoptosis after fas cross-linking. |
1998-04-02 |
2023-08-12 |
Not clear |
| R De Maria, M R Rippo, E H Schuchman, R Test. Acidic sphingomyelinase (ASM) is necessary for fas-induced GD3 ganglioside accumulation and efficient apoptosis of lymphoid cells. The Journal of experimental medicine. vol 187. issue 6. 1998-04-02. PMID:9500792. |
inefficient apoptosis is due to lack of asm activity, because proximal signaling from fas in npd lymphoblasts is not impaired and apoptosis can be efficiently triggered by passing the asm defect with exogenous ceramides. |
1998-04-02 |
2023-08-12 |
Not clear |
| R De Maria, M R Rippo, E H Schuchman, R Test. Acidic sphingomyelinase (ASM) is necessary for fas-induced GD3 ganglioside accumulation and efficient apoptosis of lymphoid cells. The Journal of experimental medicine. vol 187. issue 6. 1998-04-02. PMID:9500792. |
moreover, mannose receptor-mediated transfer of asm into npd lymphoblasts rescues their ability to transiently activate asm, accumulate gd3, and rapidly undergo apoptosis after fas cross-linking. |
1998-04-02 |
2023-08-12 |
Not clear |
| J D Mountz, J Wu, T Zhou, H C Hs. Cell death and longevity: implications of Fas-mediated apoptosis in T-cell senescence. Immunological reviews. vol 160. 1998-04-01. PMID:9476662. |
we have previously shown that t-cell senescence is greatly reduced in cd2-fas transgenic mice, in which the fas apoptosis molecule is constantly expressed on t cells. |
1998-04-01 |
2023-08-12 |
mouse |
| D S Richardson, S A Johnso. Anthracyclines in haematology: preclinical studies, toxicity and delivery systems. Blood reviews. vol 11. issue 4. 1998-03-31. PMID:9481450. |
more recently, workers have focused on induction of apoptosis and have shown that daunorubicin stimulates production of the apoptotic mediator, ceramide and that the activity of doxorubicin can be blocked by inhibitors of cd95 (fas). |
1998-03-31 |
2023-08-12 |
Not clear |
| S Andjelic, H C Lio. Antigen receptor-induced B lymphocyte apoptosis mediated via a protease of the caspase family. European journal of immunology. vol 28. issue 2. 1998-03-31. PMID:9521067. |
it is well established that the caspases are essential for the apoptosis mediated by fas (cd95) and tnf receptor p55, molecules that contain the "death domain" in the cytoplasmic tail. |
1998-03-31 |
2023-08-12 |
Not clear |
| C L Yu, M H Huang, C Y Tsai, Y Y Tsai, S T Tsai, K H Sun, S H Han, H S Y. The effect of human polyclonal anti-dsDNA autoantibodies on apoptotic gene expression in cultured rat glomerular mesangial cells. Scandinavian journal of rheumatology. vol 27. issue 1. 1998-03-30. PMID:9506879. |
the results suggest that anti-dsdna induce rmc apoptosis via an unidentified mechanism different from fas, c-myc or p53 pathway. |
1998-03-30 |
2023-08-12 |
mouse |
| C W Benjamin, R R Hiebsch, D A Jone. Caspase activation in MCF7 cells responding to etoposide treatment. Molecular pharmacology. vol 53. issue 3. 1998-03-27. PMID:9495810. |
although the pathways through which chemotherapeutics promote cell death remain largely unknown, caspase proteases play a central role in the induction of apoptosis in response to a variety of stimuli including tumor necrosis factor, fas ligand, and growth factor deprivation. |
1998-03-27 |
2023-08-12 |
human |
| T H Holmström, S C Chow, I Elo, E T Coffey, S Orrenius, L Sistonen, J E Eriksso. Suppression of Fas/APO-1-mediated apoptosis by mitogen-activated kinase signaling. Journal of immunology (Baltimore, Md. : 1950). vol 160. issue 6. 1998-03-26. PMID:9510160. |
the role of mapk in modulation of fas-mediated apoptosis was further corroborated by transient transfection with constitutively active mapk kinase, resulting in complete inhibition of the fas response, whereas transfection with a dominant negative form of mapk kinase had no effect. |
1998-03-26 |
2023-08-12 |
Not clear |
| L Genestier, A F Prigent, R Paillot, L Quemeneur, I Durand, J Banchereau, J P Revillard, N Bonnefoy-Bérar. Caspase-dependent ceramide production in Fas- and HLA class I-mediated peripheral T cell apoptosis. The Journal of biological chemistry. vol 273. issue 9. 1998-03-25. PMID:9478956. |
we analyzed the signaling pathway involved in hla class i-mediated apoptosis in comparison with fas (apo-1, cd95)-dependent apoptosis. |
1998-03-25 |
2023-08-12 |
mouse |
| A Algeciras, D H Dockrell, D H Lynch, C V Pay. CD4 regulates susceptibility to Fas ligand- and tumor necrosis factor-mediated apoptosis. The Journal of experimental medicine. vol 187. issue 5. 1998-03-24. PMID:9480981. |
cd4 regulates susceptibility to fas ligand- and tumor necrosis factor-mediated apoptosis. |
1998-03-24 |
2023-08-12 |
human |
| J H Gill, N H James, R A Roberts, C Div. The non-genotoxic hepatocarcinogen nafenopin suppresses rodent hepatocyte apoptosis induced by TGFbeta1, DNA damage and Fas. Carcinogenesis. vol 19. issue 2. 1998-03-24. PMID:9498280. |
the non-genotoxic hepatocarcinogen nafenopin suppresses rodent hepatocyte apoptosis induced by tgfbeta1, dna damage and fas. |
1998-03-24 |
2023-08-12 |
mouse |
| T Fan, H Lu, H Hu, L Shi, G A McClarty, D M Nance, A H Greenberg, G Zhon. Inhibition of apoptosis in chlamydia-infected cells: blockade of mitochondrial cytochrome c release and caspase activation. The Journal of experimental medicine. vol 187. issue 4. 1998-03-23. PMID:9463399. |
chlamydia-infected host cells are profoundly resistant to apoptosis induced by a wide spectrum of proapoptotic stimuli including the kinase inhibitor staurosporine, the dna-damaging agent etoposide, and several immunological apoptosis-inducing molecules such as tumor necrosis factor-alpha, fas antibody, and granzyme b/perforin. |
1998-03-23 |
2023-08-12 |
Not clear |
| A Srinivasan, F Li, A Wong, L Kodandapani, R Smidt, J F Krebs, L C Fritz, J C Wu, K J Tomasell. Bcl-xL functions downstream of caspase-8 to inhibit Fas- and tumor necrosis factor receptor 1-induced apoptosis of MCF7 breast carcinoma cells. The Journal of biological chemistry. vol 273. issue 8. 1998-03-19. PMID:9468507. |
stimulation of the fas or tumor necrosis factor receptor 1 (tnfr1) cell surface receptors leads to the activation of the death effector protease, caspase-8, and subsequent apoptosis. |
1998-03-19 |
2023-08-12 |
human |
| A Srinivasan, F Li, A Wong, L Kodandapani, R Smidt, J F Krebs, L C Fritz, J C Wu, K J Tomasell. Bcl-xL functions downstream of caspase-8 to inhibit Fas- and tumor necrosis factor receptor 1-induced apoptosis of MCF7 breast carcinoma cells. The Journal of biological chemistry. vol 273. issue 8. 1998-03-19. PMID:9468507. |
to address the effect of bcl-xl on caspase-8 processing, fas- and tnfr1-mediated apoptosis were studied in the mcf7 breast carcinoma cell line stably transfected with human fas cdna (mcf7/f) or double transfected with fas and human bcl-xl cdnas (mcf7/fb). |
1998-03-19 |
2023-08-12 |
human |
| Y Li, J Kang, M S Horwit. Interaction of an adenovirus E3 14.7-kilodalton protein with a novel tumor necrosis factor alpha-inducible cellular protein containing leucine zipper domains. Molecular and cellular biology. vol 18. issue 3. 1998-03-19. PMID:9488477. |
fip-2 by itself does not cause cell death; however, it can reverse the protective effect of e3-14.7k on cell killing induced by overexpression of the intracellular domain of the 55-kda tnf receptor or by rip, a death protein involved in the tnf-alpha and fas apoptosis pathways. |
1998-03-19 |
2023-08-12 |
human |
| H Okada, R Takei, M Tashir. Inhibition of HIV-1 Nef-induced apoptosis of uninfected human blood cells by serine/threonine protein kinase inhibitors, fasudil hydrochloride and M3. FEBS letters. vol 422. issue 3. 1998-03-19. PMID:9498817. |
the nef-induced apoptosis also occurs with blood cells not expressing cd95 (fas). |
1998-03-19 |
2023-08-12 |
human |
| H Hu. Fas-mediated apoptosis in tumor formation and defense. Biological chemistry. vol 378. issue 12. 1998-03-18. PMID:9461339. |
fas ligand is a specific death factor that induces apoptosis by binding to its receptor fas. |
1998-03-18 |
2023-08-12 |
Not clear |
| H Hu. Fas-mediated apoptosis in tumor formation and defense. Biological chemistry. vol 378. issue 12. 1998-03-18. PMID:9461339. |
expression of fas ligand in tumor cells resistant to fas-mediated apoptosis helps the tumor to escape surveillance by the immune system. |
1998-03-18 |
2023-08-12 |
Not clear |
| H Hu. Fas-mediated apoptosis in tumor formation and defense. Biological chemistry. vol 378. issue 12. 1998-03-18. PMID:9461339. |
inducing apoptosis in the attacking lymphocytes resembles the mechanism of how fas ligand contributes to the maintenance of immune privilege. |
1998-03-18 |
2023-08-12 |
Not clear |