| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Morimoto, H Morimoto, H Okamura, K Nomiyama, N Nakamuta, S Kobayashi, S Kito, T Ohba, T Hanej. Upregulation of the expression of Fas antigen and Fas ligand in a human submandibular gland ductal cell line by okadaic acid. Archives of oral biology. vol 45. issue 8. 2000-08-18. PMID:10869477. |
the results indicate that the expression of fas receptor and ligand is regulated by protein phosphatase(s) sensitive to okadaic acid and is involved in okadaic acid-induced apoptosis in hsg cells. |
2000-08-18 |
2023-08-12 |
human |
| Y Morimoto, H Morimoto, H Okamura, K Nomiyama, N Nakamuta, S Kobayashi, S Kito, T Ohba, T Hanej. Upregulation of the expression of Fas antigen and Fas ligand in a human submandibular gland ductal cell line by okadaic acid. Archives of oral biology. vol 45. issue 8. 2000-08-18. PMID:10869477. |
the results also suggest that the fas receptor-ligand system might regulate apoptosis in hsg cells. |
2000-08-18 |
2023-08-12 |
human |
| M Ahmad, Y Sh. TRAIL-induced apoptosis of thyroid cancer cells: potential for therapeutic intervention. Oncogene. vol 19. issue 30. 2000-08-18. PMID:10918593. |
to determine whether the apoptotic machinery of thyroid cancer cells is functional and could be activated for tumoricidal purposes, we examined the apoptosis induced by the cytokines tnf-alpha, fas and trail in thyroid cancer cell lines, npa and sw579. |
2000-08-18 |
2023-08-12 |
Not clear |
| M Ahmad, Y Sh. TRAIL-induced apoptosis of thyroid cancer cells: potential for therapeutic intervention. Oncogene. vol 19. issue 30. 2000-08-18. PMID:10918593. |
the apoptosis induced by agonistic fas ab could be seen only after a prolonged exposure (24 h) to chx, whereas tnf-alpha had no effect even in the presence of chx. |
2000-08-18 |
2023-08-12 |
Not clear |
| M Ahmad, Y Sh. TRAIL-induced apoptosis of thyroid cancer cells: potential for therapeutic intervention. Oncogene. vol 19. issue 30. 2000-08-18. PMID:10918593. |
again trail was more potent in triggering apoptosis than fas and tnf-alpha. |
2000-08-18 |
2023-08-12 |
Not clear |
| J O'Connell, M W Bennett, K Nally, A Houston, G C O'Sullivan, F Shanaha. Altered mechanisms of apoptosis in colon cancer: Fas resistance and counterattack in the tumor-immune conflict. Annals of the New York Academy of Sciences. vol 910. 2000-08-17. PMID:10911913. |
altered mechanisms of apoptosis in colon cancer: fas resistance and counterattack in the tumor-immune conflict. |
2000-08-17 |
2023-08-12 |
Not clear |
| J O'Connell, M W Bennett, K Nally, A Houston, G C O'Sullivan, F Shanaha. Altered mechanisms of apoptosis in colon cancer: Fas resistance and counterattack in the tumor-immune conflict. Annals of the New York Academy of Sciences. vol 910. 2000-08-17. PMID:10911913. |
fas (cd95/apo-1) is a cell surface "death receptor" that mediates apoptosis upon engagement by its ligand, fasl. |
2000-08-17 |
2023-08-12 |
Not clear |
| J O'Connell, M W Bennett, K Nally, A Houston, G C O'Sullivan, F Shanaha. Altered mechanisms of apoptosis in colon cancer: Fas resistance and counterattack in the tumor-immune conflict. Annals of the New York Academy of Sciences. vol 910. 2000-08-17. PMID:10911913. |
normal colonic epithelial cells express fas and are relatively sensitive to fas-mediated apoptosis. |
2000-08-17 |
2023-08-12 |
Not clear |
| J O'Connell, M W Bennett, K Nally, A Houston, G C O'Sullivan, F Shanaha. Altered mechanisms of apoptosis in colon cancer: Fas resistance and counterattack in the tumor-immune conflict. Annals of the New York Academy of Sciences. vol 910. 2000-08-17. PMID:10911913. |
by contrast, colon tumor-derived cell lines are usually resistant to induction of fas-mediated apoptosis, and colon cancer cells frequently coexpress fas and fasl. |
2000-08-17 |
2023-08-12 |
Not clear |
| J O'Connell, M W Bennett, K Nally, A Houston, G C O'Sullivan, F Shanaha. Altered mechanisms of apoptosis in colon cancer: Fas resistance and counterattack in the tumor-immune conflict. Annals of the New York Academy of Sciences. vol 910. 2000-08-17. PMID:10911913. |
the mechanisms allowing resistance to fas-mediated apoptosis are complex, and defects have been identified at several levels of fas signal transduction. |
2000-08-17 |
2023-08-12 |
Not clear |
| S O'Neill, A J O'Neill, E Conroy, H R Brady, J M Fitzpatrick, R W Watso. Altered caspase expression results in delayed neutrophil apoptosis in acute pancreatitis. Journal of leukocyte biology. vol 68. issue 1. 2000-08-17. PMID:10914485. |
isolated neutrophils were resistant to fas antibody-induced apoptosis. |
2000-08-17 |
2023-08-12 |
Not clear |
| S O'Neill, A J O'Neill, E Conroy, H R Brady, J M Fitzpatrick, R W Watso. Altered caspase expression results in delayed neutrophil apoptosis in acute pancreatitis. Journal of leukocyte biology. vol 68. issue 1. 2000-08-17. PMID:10914485. |
caspases represent a central mechanism for spontaneous and fas antibody-induced neutrophil apoptosis. |
2000-08-17 |
2023-08-12 |
Not clear |
| M Volm, R Koomäg. Hypoxia-inducible factor (HIF-1) and its relationship to apoptosis and proliferation in lung cancer. Anticancer research. vol 20. issue 3A. 2000-08-17. PMID:10928066. |
however, a significant correlation between hif-1 expression, apoptosis and the pro-apoptotic factors caspase-3, fas, and fas ligand could be detected. |
2000-08-17 |
2023-08-12 |
Not clear |
| Y Ito, T Takeda, M Sakon, M Tsujimoto, N Matsuur. Fas-Fas ligand pathway does not actively work in extrahepatic bile duct carcinoma. Anticancer research. vol 20. issue 3B. 2000-08-17. PMID:10928141. |
these results suggest that, although bdc and ac very frequently express fas, fas-mediated apoptosis is only occasionally induced in carcinoma cells because of the lack of fas ligand expression in infiltrating mononuclear cells in these carcinomas. |
2000-08-17 |
2023-08-12 |
Not clear |
| N Shinoura, M Ohashi, Y Yoshida, T Kirino, A Asai, M Hashimoto, H Hamad. Adenovirus-mediated overexpression of Fas induces apoptosis of gliomas. Cancer gene therapy. vol 7. issue 2. 2000-08-10. PMID:10770630. |
adenovirus-mediated overexpression of fas induces apoptosis of gliomas. |
2000-08-10 |
2023-08-12 |
Not clear |
| N Shinoura, M Ohashi, Y Yoshida, T Kirino, A Asai, M Hashimoto, H Hamad. Adenovirus-mediated overexpression of Fas induces apoptosis of gliomas. Cancer gene therapy. vol 7. issue 2. 2000-08-10. PMID:10770630. |
in u251 cells and a-172 cells that express the same level of fas as a result of infection with adeno-fas, a much higher percentage of u251 cells underwent apoptosis than did a-172 cells. |
2000-08-10 |
2023-08-12 |
Not clear |
| N Shinoura, M Ohashi, Y Yoshida, T Kirino, A Asai, M Hashimoto, H Hamad. Adenovirus-mediated overexpression of Fas induces apoptosis of gliomas. Cancer gene therapy. vol 7. issue 2. 2000-08-10. PMID:10770630. |
this suggests that each glioma cell line has its own threshold of fas expression, above which apoptosis is induced, and that the constitutive expression of fas is below the level of this threshold. |
2000-08-10 |
2023-08-12 |
Not clear |
| N Shinoura, M Ohashi, Y Yoshida, T Kirino, A Asai, M Hashimoto, H Hamad. Adenovirus-mediated overexpression of Fas induces apoptosis of gliomas. Cancer gene therapy. vol 7. issue 2. 2000-08-10. PMID:10770630. |
when u251 and u-373 mg cells were transduced with the fas gene controlled by the myelin basic protein promoter, which had been shown to be active in gliomas but not in neural tissues, the cells underwent markedly enhanced apoptosis. |
2000-08-10 |
2023-08-12 |
Not clear |
| N Shinoura, M Ohashi, Y Yoshida, T Kirino, A Asai, M Hashimoto, H Hamad. Adenovirus-mediated overexpression of Fas induces apoptosis of gliomas. Cancer gene therapy. vol 7. issue 2. 2000-08-10. PMID:10770630. |
taken together, these results indicate that the overexpression of fas alone induced apoptosis in each glioma cell line. |
2000-08-10 |
2023-08-12 |
Not clear |
| I Choi, K Muta, A Wickrema, S B Krantz, J Nishimura, H Nawat. Interferon gamma delays apoptosis of mature erythroid progenitor cells in the absence of erythropoietin. Blood. vol 95. issue 12. 2000-08-10. PMID:10845905. |
we propose that ifn-gamma produces a stimulating signal for the survival of mature erythroid progenitor cells by reducing apoptosis through a mechanism other than modulating fas and one related to the expression of bcl-x. |
2000-08-10 |
2023-08-12 |
human |