| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P D Arkwright, F Rieux-Laucat, F Le Deist, R F Stevens, B Angus, A J Can. Cytomegalovirus infection in infants with autoimmune lymphoproliferative syndrome (ALPS). Clinical and experimental immunology. vol 121. issue 2. 2000-08-28. PMID:10931153. |
cytomegalovirus (cmv) infection in two brothers with fas deficiency associated with autoimmunity and benign lymphoproliferation (alps) provided a unique opportunity to study the clinical course of cmv infection in children with defective apoptosis. |
2000-08-28 |
2023-08-12 |
Not clear |
| P D Arkwright, F Rieux-Laucat, F Le Deist, R F Stevens, B Angus, A J Can. Cytomegalovirus infection in infants with autoimmune lymphoproliferative syndrome (ALPS). Clinical and experimental immunology. vol 121. issue 2. 2000-08-28. PMID:10931153. |
alps was confirmed by in vitro anti-cd95 moab-induced t lymphocyte apoptosis assay and subsequent sequencing and identification of mutations in the fas gene. |
2000-08-28 |
2023-08-12 |
Not clear |
| J Desbarats, M K Newel. Fas engagement accelerates liver regeneration after partial hepatectomy. Nature medicine. vol 6. issue 8. 2000-08-28. PMID:10932231. |
here we show that partial hepatectomy, which triggers the immediate onset of liver regeneration, protected mice against the lethal effects of fas-specific antibodies and prevented hepatocyte apoptosis in response to fas engagement in vivo. |
2000-08-28 |
2023-08-12 |
mouse |
| M Martínez, E Fernández-Vivancos, A Frank, M De la Fuente, A Hernan. Increased cerebrospinal fluid fas (Apo-1) levels in Alzheimer's disease. Relationship with IL-6 concentrations. Brain research. vol 869. issue 1-2. 2000-08-25. PMID:10865077. |
increasing lines of evidence suggest a role of apoptosis in the neurodegeneration associated with alzheimer's disease, in which it has been implicated in increasing the expression of p53 and fas. |
2000-08-25 |
2023-08-12 |
Not clear |
| S H Gregory, C C Li. CD8+ T-cell-mediated response to Listeria monocytogenes taken up in the liver and replicating within hepatocytes. Immunological reviews. vol 174. 2000-08-24. PMID:10807511. |
evidence demonstrating the perforin- and/or fas ligand-dependent induction of caspase activity and the resultant apoptosis of listeria-infected hepatocytes is discussed. |
2000-08-24 |
2023-08-12 |
mouse |
| H Tsutsui, K Matsui, H Okamura, K Nakanish. Pathophysiological roles of interleukin-18 in inflammatory liver diseases. Immunological reviews. vol 174. 2000-08-24. PMID:10807517. |
propionibacterium acnes-primed lipopolysaccharide (lps)-challenged liver injury is the prototype of il-18-induced tissue injury, in which il-18 acts on natural killer cells to increase fas ligand (fasl) that causes liver injury by induction of fas-dependent hepatocyte apoptosis. |
2000-08-24 |
2023-08-12 |
mouse |
| S M Quirk, R M Harman, S C Huber, R G Cowa. Responsiveness of mouse corpora luteal cells to Fas antigen (CD95)-mediated apoptosis. Biology of reproduction. vol 63. issue 1. 2000-08-24. PMID:10859241. |
responsiveness of mouse corpora luteal cells to fas antigen (cd95)-mediated apoptosis. |
2000-08-24 |
2023-08-12 |
mouse |
| S M Quirk, R M Harman, S C Huber, R G Cowa. Responsiveness of mouse corpora luteal cells to Fas antigen (CD95)-mediated apoptosis. Biology of reproduction. vol 63. issue 1. 2000-08-24. PMID:10859241. |
the fas antigen (fas) is a cell surface receptor that induces apoptosis in sensitive cells when bound to fas ligand or agonistic anti-fas monoclonal antibodies (fas mab). |
2000-08-24 |
2023-08-12 |
mouse |
| S M Quirk, R M Harman, S C Huber, R G Cowa. Responsiveness of mouse corpora luteal cells to Fas antigen (CD95)-mediated apoptosis. Biology of reproduction. vol 63. issue 1. 2000-08-24. PMID:10859241. |
a potential role for fas to induce apoptosis in dispersed cl cell preparations was tested in cells isolated from mice on days 2-4 of pseudopregnancy. |
2000-08-24 |
2023-08-12 |
mouse |
| T Niinobu, K Fukuo, O Yasuda, M Tsubakimoto, M Mogi, H Nishimaki, S Morimoto, T Ogihar. Negative feedback regulation of activated macrophages via Fas-mediated apoptosis. American journal of physiology. Cell physiology. vol 279. issue 2. 2000-08-24. PMID:10913017. |
this no-induced macrophage apoptosis was inhibited by a fas-fc chimeric molecule that binds to fas ligand (fasl) and prevents its interaction with endogenous cell surface fas. |
2000-08-24 |
2023-08-12 |
mouse |
| M S Sheikh, A J Fornac. Death and decoy receptors and p53-mediated apoptosis. Leukemia. vol 14. issue 8. 2000-08-24. PMID:10942251. |
recent evidence suggests that p53 upregulates the expression of death receptors fas and dr5, and thus, may mediate apoptosis in part via fas and/or dr5. |
2000-08-24 |
2023-08-12 |
Not clear |
| M R Verneris, M Kornacker, V Mailänder, R S Negri. Resistance of ex vivo expanded CD3+CD56+ T cells to Fas-mediated apoptosis. Cancer immunology, immunotherapy : CII. vol 49. issue 6. 2000-08-24. PMID:10946816. |
a variety of malignancies express fas ligand (fasl), which can induce apoptosis in effector lymphocytes and may limit the success of cellular immunotherapy. |
2000-08-24 |
2023-08-12 |
Not clear |
| M R Verneris, M Kornacker, V Mailänder, R S Negri. Resistance of ex vivo expanded CD3+CD56+ T cells to Fas-mediated apoptosis. Cancer immunology, immunotherapy : CII. vol 49. issue 6. 2000-08-24. PMID:10946816. |
fas engagement leads to apoptosis in small numbers of cik cells and does not significantly influence antitumor cytotoxicity. |
2000-08-24 |
2023-08-12 |
Not clear |
| M R Verneris, M Kornacker, V Mailänder, R S Negri. Resistance of ex vivo expanded CD3+CD56+ T cells to Fas-mediated apoptosis. Cancer immunology, immunotherapy : CII. vol 49. issue 6. 2000-08-24. PMID:10946816. |
cik cells will undergo apoptosis following fas engagement when protein synthesis is inhibited, suggesting the expression of antiapoptotic genes. |
2000-08-24 |
2023-08-12 |
Not clear |
| M R Verneris, M Kornacker, V Mailänder, R S Negri. Resistance of ex vivo expanded CD3+CD56+ T cells to Fas-mediated apoptosis. Cancer immunology, immunotherapy : CII. vol 49. issue 6. 2000-08-24. PMID:10946816. |
resistance to fas-mediated apoptosis may come about through an in vitro selection for fas resistance, since cik cells synthesize fasl and supernatant from cik cultures contains biologically active soluble fasl, which can be inhibited with fas:fc. |
2000-08-24 |
2023-08-12 |
Not clear |
| A Villunger, D C Huang, N Holler, J Tschopp, A Strasse. Fas ligand-induced c-Jun kinase activation in lymphoid cells requires extensive receptor aggregation but is independent of DAXX, and Fas-mediated cell death does not involve DAXX, RIP, or RAIDD. Journal of immunology (Baltimore, Md. : 1950). vol 165. issue 3. 2000-08-22. PMID:10903735. |
daxx and other death receptor-associated proteins, which have been reported to bind directly or indirectly to fas, such as receptor interacting protein (rip) and rip-associated ich-1/ced-3-homologous protein with a death domain (raidd), were shown to be dispensable for fas ligand-induced apoptosis. |
2000-08-22 |
2023-08-12 |
Not clear |
| T Reya, M O'Riordan, R Okamura, E Devaney, K Willert, R Nusse, R Grossched. Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism. Immunity. vol 13. issue 1. 2000-08-22. PMID:10933391. |
we further show that lef1-/- pro-b cells display elevated levels of fas and c-myc transcription, providing a potential mechanism for their increased sensitivity to apoptosis. |
2000-08-22 |
2023-08-12 |
mouse |
| E O'Flaherty, W K Wong, S J Pettit, K Seymour, S Ali, J A Kirb. Regulation of T-cell apoptosis: a mixed lymphocyte reaction model. Immunology. vol 100. issue 3. 2000-08-21. PMID:10929050. |
however, these t cells were resistant for up to 5 days to apoptosis following the stimulation of fas; a maximal apoptotic response was observed after 7 days. |
2000-08-21 |
2023-08-12 |
Not clear |
| E O'Flaherty, W K Wong, S J Pettit, K Seymour, S Ali, J A Kirb. Regulation of T-cell apoptosis: a mixed lymphocyte reaction model. Immunology. vol 100. issue 3. 2000-08-21. PMID:10929050. |
in this study, it is shown that t cells are resistant to apoptosis for the first 5 days after activation as a consequence of insensitivity of the fas pathway and the presence of intracellular bcl-2. |
2000-08-21 |
2023-08-12 |
Not clear |
| E O'Flaherty, W K Wong, S J Pettit, K Seymour, S Ali, J A Kirb. Regulation of T-cell apoptosis: a mixed lymphocyte reaction model. Immunology. vol 100. issue 3. 2000-08-21. PMID:10929050. |
at later time points, fas ligation is reduced but the cells respond to a decreased availability of il-2 by reducing bcl-2 expression; this encourages further apoptosis by allowing the direct activation of caspase enzymes. |
2000-08-21 |
2023-08-12 |
Not clear |