| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N Taya, Y Torimoto, M Shindo, K Hirai, C Hasebe, Y Kohg. Fas-mediated apoptosis of peripheral blood mononuclear cells in patients with hepatitis C. British journal of haematology. vol 110. issue 1. 2000-09-13. PMID:10930983. |
these results suggest that hcv infection of pbmcs might induce fas expression and additional stimulation such as sfasl might induce apoptosis in these fas-expressing cells. |
2000-09-13 |
2023-08-12 |
human |
| M Raitakari, R D Brown, D Sze, E Yuen, L Barrow, M Nelson, B Pope, W Esdale, J Gibson, D E Joshu. T-cell expansions in patients with multiple myeloma have a phenotype of cytotoxic T cells. British journal of haematology. vol 110. issue 1. 2000-09-13. PMID:10930999. |
the expression of the apoptosis markers fas (cd95) and bcl-2 were similar between the expanded and non-expanded vbeta populations. |
2000-09-13 |
2023-08-12 |
Not clear |
| T Hara, H Tsurumi, M Takemura, H Goto, T Yamada, M Sawada, T Takahashi, H Moriwak. Serum-soluble fas level determines clinical symptoms and outcome of patients with aggressive non-Hodgkin's lymphoma. American journal of hematology. vol 64. issue 4. 2000-09-12. PMID:10911377. |
soluble fas (sfas) blocks apoptosis induced by fas ligand in vitro. |
2000-09-12 |
2023-08-12 |
Not clear |
| A Gutiérrez del Arroyo, C Gil-Lamagniere, I Lazaro, M C de Marco, I Layunta, A Silv. Involvement of p53 and interleukin 3 in the up-regulation of CD95 (APO-1/Fas) by X-ray irradiation. Oncogene. vol 19. issue 32. 2000-09-12. PMID:10951571. |
therefore, in il-3-dependent cells, il-3 regulates the rate of fas expression, which is correlated with the degree of apoptosis observed in x-irradiated cells. |
2000-09-12 |
2023-08-12 |
mouse |
| J Gil, M Esteba. The interferon-induced protein kinase (PKR), triggers apoptosis through FADD-mediated activation of caspase 8 in a manner independent of Fas and TNF-alpha receptors. Oncogene. vol 19. issue 32. 2000-09-12. PMID:10951573. |
the interferon-induced protein kinase (pkr), triggers apoptosis through fadd-mediated activation of caspase 8 in a manner independent of fas and tnf-alpha receptors. |
2000-09-12 |
2023-08-12 |
Not clear |
| J Gil, M Esteba. The interferon-induced protein kinase (PKR), triggers apoptosis through FADD-mediated activation of caspase 8 in a manner independent of Fas and TNF-alpha receptors. Oncogene. vol 19. issue 32. 2000-09-12. PMID:10951573. |
upregulation of fas mrna by pkr has been suggested to play a role in pkr-induced apoptosis. |
2000-09-12 |
2023-08-12 |
Not clear |
| J Gil, M Esteba. The interferon-induced protein kinase (PKR), triggers apoptosis through FADD-mediated activation of caspase 8 in a manner independent of Fas and TNF-alpha receptors. Oncogene. vol 19. issue 32. 2000-09-12. PMID:10951573. |
significantly, despite the pkr-mediated upregulation of fas mrna expression, the fas receptor-ligand pathway is not needed for pkr-induced apoptosis. |
2000-09-12 |
2023-08-12 |
Not clear |
| J Gil, M Esteba. The interferon-induced protein kinase (PKR), triggers apoptosis through FADD-mediated activation of caspase 8 in a manner independent of Fas and TNF-alpha receptors. Oncogene. vol 19. issue 32. 2000-09-12. PMID:10951573. |
taken together, our observations establish the involvement of caspase 8 in pkr-induced apoptosis and suggest that death receptors other than fas or tnfr1 or, alternatively, a novel mechanism involving fadd independently of death receptors, are responsible for pkr-induced apoptosis. |
2000-09-12 |
2023-08-12 |
Not clear |
| P M Yao, I Taba. Free cholesterol loading of macrophages induces apoptosis involving the fas pathway. The Journal of biological chemistry. vol 275. issue 31. 2000-09-07. PMID:10791964. |
free cholesterol loading of macrophages induces apoptosis involving the fas pathway. |
2000-09-07 |
2023-08-12 |
mouse |
| P M Yao, I Taba. Free cholesterol loading of macrophages induces apoptosis involving the fas pathway. The Journal of biological chemistry. vol 275. issue 31. 2000-09-07. PMID:10791964. |
macrophages from mice with mutations in either fas or fas ligand (fasl) demonstrated substantial resistance to fc-induced apoptosis, and fc-induced death in wild-type macrophages was blocked by an anti-fasl antibody. |
2000-09-07 |
2023-08-12 |
mouse |
| Q R Huang, N Manolio. Investigation of the -1377 polymorphism on the Apo-1/Fas promoter in systemic lupus erythematosus patients using allele-specific amplification. Pathology. vol 32. issue 2. 2000-09-07. PMID:10840834. |
apoptosis mediated by the apo-1/fas and fas ligand pathways has been implicated in many disorders, including autoimmunity and tumorigenesis. |
2000-09-07 |
2023-08-12 |
human |
| M Sato, T Konuma, N Yanagisawa, H Haizuka, H Asakura, Y Nakashim. Fas-Fas ligand system in the peripheral blood of patients with renal diseases. Nephron. vol 85. issue 2. 2000-09-06. PMID:10867515. |
these results indicate that fas expression on mncs is activated in accordance with the deterioration in renal function without disease specificity, corresponding to the elevation of serum sfas levels to protect against fas-mediated apoptosis. |
2000-09-06 |
2023-08-12 |
Not clear |
| N Mitsiades, V Poulaki, S Tseleni-Balafouta, D A Koutras, I Stamenkovi. Thyroid carcinoma cells are resistant to FAS-mediated apoptosis but sensitive to tumor necrosis factor-related apoptosis-inducing ligand. Cancer research. vol 60. issue 15. 2000-08-31. PMID:10945619. |
fas (apo-1/cd95) is a transmembrane protein of the tumor necrosis factor (tnf)/nerve growth factor receptor superfamily that induces apoptosis in susceptible normal and neoplastic cells upon cross-linking by its ligand (fasl). |
2000-08-31 |
2023-08-12 |
Not clear |
| N Mitsiades, V Poulaki, S Tseleni-Balafouta, D A Koutras, I Stamenkovi. Thyroid carcinoma cells are resistant to FAS-mediated apoptosis but sensitive to tumor necrosis factor-related apoptosis-inducing ligand. Cancer research. vol 60. issue 15. 2000-08-31. PMID:10945619. |
we addressed the expression of fas, dr4, and dr5 in thyroid carcinoma cell lines and in 31 thyroid carcinoma specimens by western blot analysis and immunohistochemistry, respectively, and tested the sensitivity of thyroid carcinoma cell lines to fas- and trail-induced apoptosis. |
2000-08-31 |
2023-08-12 |
Not clear |
| N Mitsiades, V Poulaki, S Tseleni-Balafouta, D A Koutras, I Stamenkovi. Thyroid carcinoma cells are resistant to FAS-mediated apoptosis but sensitive to tumor necrosis factor-related apoptosis-inducing ligand. Cancer research. vol 60. issue 15. 2000-08-31. PMID:10945619. |
although cross-linking of fas did not induce apoptosis in thyroid carcinoma cell lines, fas-mediated apoptosis did occur in the presence of the protein synthesis inhibitor cycloheximide, suggesting the presence of a short-lived inhibitor of the fas pathway in these cells. |
2000-08-31 |
2023-08-12 |
Not clear |
| M Kakizo. Apoptosis in giant cell tumors of bone. The Kurume medical journal. vol 47. issue 2. 2000-08-31. PMID:10948650. |
we focused on fas that is a major trigger of apoptosis. |
2000-08-31 |
2023-08-12 |
Not clear |
| P Fiorina, E Astorri, R Albertini, A Secchi, A Mello, M Lanfredini, A Craveri, G Olivetti, F Quain. Soluble antiapoptotic molecules and immune activation in chronic heart failure and unstable angina pectoris. Journal of clinical immunology. vol 20. issue 2. 2000-08-30. PMID:10821461. |
our aim was to evaluate the role of changes in circulating levels of soluble fas (sfas), suggestive of an enhanced inhibitory response to ongoing apoptosis, and soluble il2 receptor (sil2-r), indicative of t-lymphocyte activation, in chronic heart failure and unstable angina pectoris. |
2000-08-30 |
2023-08-12 |
Not clear |
| K Tokushige, N Yamaguchi, I Ikeda, E Hashimoto, K Yamauchi, N Hayash. Significance of soluble TNF receptor-I in acute-type fulminant hepatitis. The American journal of gastroenterology. vol 95. issue 8. 2000-08-30. PMID:10950055. |
fulminant hepatitis is associated with apoptosis of hepatocytes, which is mediated via fas and tumor necrosis factor (tnf) receptors. |
2000-08-30 |
2023-08-12 |
Not clear |
| K Ryo, Y Kamogawa, I Ikeda, K Yamauchi, S Yonehara, S Nagata, N Hayash. Significance of Fas antigen-mediated apoptosis in human fulminant hepatic failure. The American journal of gastroenterology. vol 95. issue 8. 2000-08-30. PMID:10950056. |
significance of fas antigen-mediated apoptosis in human fulminant hepatic failure. |
2000-08-30 |
2023-08-12 |
human |
| M C Mutomba, H Yuan, M Konyavko, S Adachi, C B Yokoyama, V Esser, J D McGarry, B M Babior, R A Gottlie. Regulation of the activity of caspases by L-carnitine and palmitoylcarnitine. FEBS letters. vol 478. issue 1-2. 2000-08-29. PMID:10922462. |
in the present study, we found that in jurkat cells, l-carnitine inhibited apoptosis induced by fas ligation. |
2000-08-29 |
2023-08-12 |
Not clear |