| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S T Eichhorst, M Müller, M Li-Weber, H Schulze-Bergkamen, P Angel, P H Kramme. A novel AP-1 element in the CD95 ligand promoter is required for induction of apoptosis in hepatocellular carcinoma cells upon treatment with anticancer drugs. Molecular and cellular biology. vol 20. issue 20. 2000-10-30. PMID:11003676. |
the cd95 (also called apo-1 or fas) system plays a major role in the induction of apoptosis in lymphoid and nonlymphoid tissues in response to a variety of extracellular signals, including chemotherapeutic drugs. |
2000-10-30 |
2023-08-12 |
Not clear |
| J L Hall, C M Matter, X Wang, G H Gibbon. Hyperglycemia inhibits vascular smooth muscle cell apoptosis through a protein kinase C-dependent pathway. Circulation research. vol 87. issue 7. 2000-10-30. PMID:11009562. |
high glucose also inhibited apoptosis induced by fas ligand (100 ng/ml) (normal 23+/-2%, high d-glucose 13+/-2%; p:<0.006). |
2000-10-30 |
2023-08-12 |
mouse |
| R Wang, G Alam, A Zagariya, C Gidea, H Pinillos, O Lalude, G Choudhary, D Oezatalay, B D Uha. Apoptosis of lung epithelial cells in response to TNF-alpha requires angiotensin II generation de novo. Journal of cellular physiology. vol 185. issue 2. 2000-10-30. PMID:11025447. |
recent work from this laboratory demonstrated that apoptosis of pulmonary alveolar epithelial cells (aec) in response to fas requires angiotensin ii (angii) generation de novo and binding to its receptor (wang et al., 1999b, am j physiol lung cell mol physiol 277:l1245-l1250). |
2000-10-30 |
2023-08-12 |
human |
| Y Li, A M McCormack, N J Brand, M H Yacou. A strategy for inducing immune tolerance to valve endothelial cells through gene transfer. The Journal of heart valve disease. vol 9. issue 3. 2000-10-27. PMID:10888103. |
fasl is an inducer of apoptosis; it binds fas and results in programmed cell death (apoptosis) of fas-bearing cells such as t lymphocytes. |
2000-10-27 |
2023-08-12 |
human |
| M C Perianayagam, S L Murray, V S Balakrishnan, D Guo, A J King, B J Pereira, B L Jabe. Serum soluble Fas (CD95) and Fas ligand profiles in chronic kidney failure. The Journal of laboratory and clinical medicine. vol 136. issue 4. 2000-10-27. PMID:11039853. |
membrane-bound fas is a cell-surface receptor that transduces apoptosis after interaction with membrane-bound or soluble fasl (sfasl). |
2000-10-27 |
2023-08-12 |
human |
| K Kawahito, Y Misawa, K Fus. Transient rise in serum soluble Fas (APO-1/CD95) in patients undergoing cardiac surgery. Artificial organs. vol 24. issue 8. 2000-10-26. PMID:10971250. |
a soluble form of fas (sfas) is produced either through the proteolytic cleavage of membrane-bound receptors or by alternative splicing, and sfas is thought to be implicated in apoptosis. |
2000-10-26 |
2023-08-12 |
Not clear |
| D M Matteson, D F Shen, C C Cha. Inhibition of experimental melanin protein-induced uveitis (EMIU) by targeting nitric oxide via phosphatidylcholine-specific phospholipase C. Journal of autoimmunity. vol 13. issue 2. 2000-10-19. PMID:10479388. |
the eyes and draining lymph nodes were collected for histology, analyses of nitrite, peroxide, and superoxide dismutase, fas and fasl immunochemistry, in situ hybridization for inos mrna and in situ apoptosis detection at the peak of the disease. |
2000-10-19 |
2023-08-12 |
rat |
| T H Holmström, J E Eriksso. Phosphorylation-Based signaling in Fas receptor-mediated apoptosis. Critical reviews in immunology. vol 20. issue 2. 2000-10-19. PMID:10872894. |
phosphorylation-based signaling in fas receptor-mediated apoptosis. |
2000-10-19 |
2023-08-12 |
Not clear |
| E Rojas Ramos, N E Martínez Jiménez, N E Martínez Aguilar, J Garfias Becerr. [Apoptosis in allergic disease]. Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993). vol 47. issue 4. 2000-10-19. PMID:10957879. |
fas (apo-1; cd95) system is one of the most important cellular responsible via to induce apoptosis on different tissues. |
2000-10-19 |
2023-08-12 |
Not clear |
| Y Nakanuma, K Tsuneyama, M Sasaki, K Harad. Destruction of bile ducts in primary biliary cirrhosis. Bailliere's best practice & research. Clinical gastroenterology. vol 14. issue 4. 2000-10-18. PMID:10976014. |
multiple factors, particularly the fas system, are stimuli of apoptosis. |
2000-10-18 |
2023-08-12 |
Not clear |
| J Crespo, M Rivero, M Mayorga, E Fabrega, F Casafont, M Gomez-Fleitas, F Pons-Romer. Involvement of the fas system in hepatitis C virus recurrence after liver transplantation. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. vol 6. issue 5. 2000-10-18. PMID:10980054. |
we conclude that (1) fas expression is up-regulated in recurrent hcv after olt and is related to the grading of liver disease; likewise, levels of sfas were greater in the patients with recurrent hcv hepatitis; and (2) the demonstration of hepatocytes with fasag expression and the labeling of the nuclei by tunel assay suggest that hepatic apoptosis mediated by the fas system may have a role in the pathogenesis of recurrent hcv hepatitis after olt. |
2000-10-18 |
2023-08-12 |
Not clear |
| J W Kim, E J Choi, C O Jo. Activation of death-inducing signaling complex (DISC) by pro-apoptotic C-terminal fragment of RIP. Oncogene. vol 19. issue 39. 2000-10-17. PMID:11002422. |
the c-terminal fragment of rip also enhanced the association between tnfr1 and death domain proteins including tnfr1 associated death domain (tradd) and fas associated death domain (fadd), resulting in the activation of caspase-8 and stimulation of apoptosis. |
2000-10-17 |
2023-08-12 |
Not clear |
| A Shanker, S M Singh, A Sodh. Ascitic growth of a spontaneous transplantable T cell lymphoma induces thymic involution. 2. Induction of apoptosis in thymocytes. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 21. issue 6. 2000-10-17. PMID:11006572. |
further, elucidation of the mechanism of apoptosis induction in thymocytes with respect to the involvement of apoptosis-related genes revealed that the death pathway followed an interleukin-1 beta-converting-enzyme-dependent, fas-mediated apoptotic cascade, with a concomitant increase in the protein products of the bax, bad, p53, fas and fasl genes and cleavage of the 23-kd n-terminal fragment of bcl-2 that exhibited bax-like death effector properties. |
2000-10-17 |
2023-08-12 |
mouse |
| L Zhuang, B Wang, D N Saude. Molecular mechanism of ultraviolet-induced keratinocyte apoptosis. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research. vol 20. issue 5. 2000-10-13. PMID:10841072. |
this article reviews advances in the study of the molecular mechanisms for ultraviolet (uv)-induced keratinocyte apoptosis, with particular reference to the cytokines tumor necrosis factor-alpha (tnf-alpha) and fas ligand (fasl). |
2000-10-13 |
2023-08-12 |
mouse |
| L Zhuang, B Wang, D N Saude. Molecular mechanism of ultraviolet-induced keratinocyte apoptosis. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research. vol 20. issue 5. 2000-10-13. PMID:10841072. |
moreover, signaling of p53 contributes to the induction of apoptosis by regulating bcl-2 family expression and increasing surface fas expression. |
2000-10-13 |
2023-08-12 |
mouse |
| G Le'Negrate, E Selva, P Auberger, B Rossi, P Hofma. Sustained polymorphonuclear leukocyte transmigration induces apoptosis in T84 intestinal epithelial cells. The Journal of cell biology. vol 150. issue 6. 2000-10-12. PMID:10995451. |
although fas and fas ligand were expressed on t84 cells and pmnls, treatment of epithelial cells with an antagonistic anti-fas antibody failed to prevent apoptosis induced by migrating pmnls. |
2000-10-12 |
2023-08-12 |
Not clear |
| M K Sharie. Impaired Fas-independent apoptosis of T lymphocytes in patients with multiple sclerosis. Journal of neuroimmunology. vol 109. issue 2. 2000-10-12. PMID:10996226. |
there is emerging evidence that apoptosis mediated by the cell death receptor fas is impaired in activated lymphocytes from patients with multiple sclerosis (ms), but other forms of apoptosis have not yet been fully evaluated. |
2000-10-12 |
2023-08-12 |
Not clear |
| Q Yao, J C Glorioso, C H Evans, P D Robbins, I Kovesdi, T J Oligino, S C Ghivizzan. Adenoviral mediated delivery of FAS ligand to arthritic joints causes extensive apoptosis in the synovial lining. The journal of gene medicine. vol 2. issue 3. 2000-10-10. PMID:10894267. |
adenoviral mediated delivery of fas ligand to arthritic joints causes extensive apoptosis in the synovial lining. |
2000-10-10 |
2023-08-12 |
Not clear |
| Q Yao, J C Glorioso, C H Evans, P D Robbins, I Kovesdi, T J Oligino, S C Ghivizzan. Adenoviral mediated delivery of FAS ligand to arthritic joints causes extensive apoptosis in the synovial lining. The journal of gene medicine. vol 2. issue 3. 2000-10-10. PMID:10894267. |
fasl, a cell-surface molecule on activated t-cells interacts with its receptor, fas, to induce apoptosis in target cells. |
2000-10-10 |
2023-08-12 |
Not clear |
| N A Cataldo, D A Dumesic, P C Goldsmith, R B Jaff. Immunolocalization of Fas and Fas ligand in the ovaries of women with polycystic ovary syndrome: relationship to apoptosis. Human reproduction (Oxford, England). vol 15. issue 9. 2000-10-10. PMID:10966981. |
immunolocalization of fas and fas ligand in the ovaries of women with polycystic ovary syndrome: relationship to apoptosis. |
2000-10-10 |
2023-08-12 |
Not clear |